ATE151815T1
(de)
*
|
1990-09-21 |
1997-05-15 |
Amgen Inc |
Enzymatische synthese von oligonukleotiden
|
US5645987A
(en)
*
|
1990-09-21 |
1997-07-08 |
Amgen Inc. |
Enzymatic synthesis of oligonucleotides
|
US5683874A
(en)
*
|
1991-03-27 |
1997-11-04 |
Research Corporation Technologies, Inc. |
Single-stranded circular oligonucleotides capable of forming a triplex with a target sequence
|
WO1994003624A1
(fr)
|
1992-08-04 |
1994-02-17 |
Auerbach Jeffrey I |
Procedes d'amplification isothermique de molecules d'acide nucleique
|
US6261808B1
(en)
|
1992-08-04 |
2001-07-17 |
Replicon, Inc. |
Amplification of nucleic acid molecules via circular replicons
|
US6077668A
(en)
*
|
1993-04-15 |
2000-06-20 |
University Of Rochester |
Highly sensitive multimeric nucleic acid probes
|
US7135312B2
(en)
|
1993-04-15 |
2006-11-14 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
US6096880A
(en)
|
1993-04-15 |
2000-08-01 |
University Of Rochester |
Circular DNA vectors for synthesis of RNA and DNA
|
US5648211A
(en)
*
|
1994-04-18 |
1997-07-15 |
Becton, Dickinson And Company |
Strand displacement amplification using thermophilic enzymes
|
US5854033A
(en)
|
1995-11-21 |
1998-12-29 |
Yale University |
Rolling circle replication reporter systems
|
WO1997019193A2
(fr)
*
|
1995-11-21 |
1997-05-29 |
Yale University |
Amplication et detection de segments unimoleculaires
|
WO1997020948A1
(fr)
*
|
1995-12-05 |
1997-06-12 |
Koch Joern Erland |
Reaction d'amplification en cascade d'acide nucleique
|
GB9609213D0
(en)
*
|
1996-05-02 |
1996-07-03 |
Tepnel Medical Ltd |
Amplification of nucleic acids
|
JP3415995B2
(ja)
*
|
1996-06-10 |
2003-06-09 |
科学技術振興事業団 |
高分子マイクロ遺伝子重合体の作成方法
|
GB9626074D0
(en)
*
|
1996-12-16 |
1997-02-05 |
Cytocell Ltd |
Nucleic acids amplification assay
|
CA2325468C
(fr)
*
|
1998-03-25 |
2008-11-18 |
Ulf Landegren |
Replication en cercle roulant destinee a des sondes cadenas
|
US6316229B1
(en)
|
1998-07-20 |
2001-11-13 |
Yale University |
Single molecule analysis target-mediated ligation of bipartite primers
|
US6255082B1
(en)
|
1998-09-15 |
2001-07-03 |
Yale University |
Artificial long terminal repeat vectors
|
EP1114184A2
(fr)
*
|
1998-09-15 |
2001-07-11 |
Yale University |
Clonage moleculaire a amplification selon le modele du cercle roulant
|
AU6471399A
(en)
*
|
1998-10-12 |
2000-05-01 |
Attomol Gmbh Molekulare Diagnostika |
Method and kit for directly detecting nucleotide sequences, amino acid sequencesor antigens
|
GB9822777D0
(en)
*
|
1998-10-20 |
1998-12-16 |
Tepnel Medical Ltd |
Template chain reaction
|
US6830884B1
(en)
|
1998-12-15 |
2004-12-14 |
Molecular Staging Inc. |
Method of amplification
|
US20020025519A1
(en)
|
1999-06-17 |
2002-02-28 |
David J. Wright |
Methods and oligonucleotides for detecting nucleic acid sequence variations
|
ATE456575T1
(de)
|
1999-10-18 |
2010-02-15 |
Prince Henrys Inst Med Res |
Immun-interaktive fragmente der alpha-c- untereinheit von inhibin
|
CA2360342A1
(fr)
|
1999-12-02 |
2001-06-07 |
Molecular Staging Inc. |
Generation d'adn circulaire a un seul brin a partir de segments lineaires de renaturation automatique
|
KR100698561B1
(ko)
|
2000-01-25 |
2007-03-21 |
더 유니버서티 어브 퀸슬랜드 |
Neisseria Meningitidis 표면 항원ΝhhΑ의 보존 부위를 포함하는 단백질
|
US6221603B1
(en)
*
|
2000-02-04 |
2001-04-24 |
Molecular Dynamics, Inc. |
Rolling circle amplification assay for nucleic acid analysis
|
US20020004592A1
(en)
*
|
2000-02-10 |
2002-01-10 |
Connor James R. |
Method for amplifying full length single strand polynucleotide sequences
|
US6291187B1
(en)
*
|
2000-05-12 |
2001-09-18 |
Molecular Staging, Inc. |
Poly-primed amplification of nucleic acid sequences
|
US6323009B1
(en)
|
2000-06-28 |
2001-11-27 |
Molecular Staging, Inc. |
Multiply-primed amplification of nucleic acid sequences
|
AU2001271722B2
(en)
|
2000-06-30 |
2006-04-13 |
Qiagen, Gmbh |
Signal amplification with lollipop probes
|
US6312913B1
(en)
*
|
2000-07-21 |
2001-11-06 |
Incyte Genomics, Inc. |
Method for isolating and characterizing nucleic acid sequences
|
AUPR030900A0
(en)
|
2000-09-22 |
2000-10-12 |
Queensland University Of Technology |
Growth factor complex
|
US6573051B2
(en)
|
2001-03-09 |
2003-06-03 |
Molecular Staging, Inc. |
Open circle probes with intramolecular stem structures
|
AUPR446701A0
(en)
|
2001-04-18 |
2001-05-17 |
Gene Stream Pty Ltd |
Transgenic mammals for pharmacological and toxicological studies
|
WO2004059289A2
(fr)
|
2001-05-22 |
2004-07-15 |
Epicentre Technologies |
Transcription fonction d'une cible utilisant des mutants de deletion d'arn polymerase n4
|
GB2378245A
(en)
|
2001-08-03 |
2003-02-05 |
Mats Nilsson |
Nucleic acid amplification method
|
US7553619B2
(en)
|
2002-02-08 |
2009-06-30 |
Qiagen Gmbh |
Detection method using dissociated rolling circle amplification
|
CA2490261A1
(fr)
|
2002-06-27 |
2004-01-08 |
The University Of Queensland |
Agents de modulation de la differenciation et utilisations associees
|
US9487823B2
(en)
|
2002-12-20 |
2016-11-08 |
Qiagen Gmbh |
Nucleic acid amplification
|
US6977153B2
(en)
|
2002-12-31 |
2005-12-20 |
Qiagen Gmbh |
Rolling circle amplification of RNA
|
US20100143442A1
(en)
|
2003-02-05 |
2010-06-10 |
Queensland University Of Technology |
Growth factor complexes and modulation of cell migration and growth
|
AU2003900481A0
(en)
|
2003-02-05 |
2003-02-20 |
Queensland University Of Technology |
Synthetic modulators of cell migration and growth
|
US8043834B2
(en)
|
2003-03-31 |
2011-10-25 |
Qiagen Gmbh |
Universal reagents for rolling circle amplification and methods of use
|
AU2003902253A0
(en)
|
2003-05-12 |
2003-05-29 |
The University Of Queensland |
Method for increasing product yield
|
WO2005108608A1
(fr)
*
|
2004-05-10 |
2005-11-17 |
Kabushiki Kaisha Dnaform |
Procédé d'isolation d'isoformes d'acide nucléique
|
CA2591659A1
(fr)
|
2004-12-17 |
2006-06-22 |
Monash University |
Regulation du clivage par des metalloproteases de proteines de surface d'une cellule
|
EP2319940A1
(fr)
*
|
2005-01-04 |
2011-05-11 |
Hitachi Chemical Company, Ltd. |
Amplification de cercle de roulement de génération d'apprêt
|
GB0504774D0
(en)
*
|
2005-03-08 |
2005-04-13 |
Lingvitae As |
Method
|
US8309303B2
(en)
|
2005-04-01 |
2012-11-13 |
Qiagen Gmbh |
Reverse transcription and amplification of RNA with simultaneous degradation of DNA
|
US8080393B2
(en)
|
2005-04-12 |
2011-12-20 |
Olink Ab |
Methods for production of oligonucleotides
|
US7989166B2
(en)
|
2005-04-12 |
2011-08-02 |
In Situ Rcp A/S |
Circle probes and their use in the identification of biomolecules
|
EP3492602A1
(fr)
|
2005-06-15 |
2019-06-05 |
Complete Genomics, Inc. |
Réseaux de molécules simples pour l'analyse génétique et chimique
|
US20090264299A1
(en)
*
|
2006-02-24 |
2009-10-22 |
Complete Genomics, Inc. |
High throughput genome sequencing on DNA arrays
|
EP1762627A1
(fr)
|
2005-09-09 |
2007-03-14 |
Qiagen GmbH |
Procédé pour l'activation d'acides nucléiques pour effectuer une réaction d'une polymérase
|
CA2624324A1
(fr)
|
2005-10-06 |
2007-04-19 |
Lucigen Corporation |
Polymerases virales thermostables, et leurs methodes d'utilisation
|
US7960104B2
(en)
*
|
2005-10-07 |
2011-06-14 |
Callida Genomics, Inc. |
Self-assembled single molecule arrays and uses thereof
|
US7501254B2
(en)
|
2006-07-20 |
2009-03-10 |
Ghc Technologies, Inc. |
Methods and compositions for amplification and capture of nucleic acid sequences
|
KR20090046876A
(ko)
|
2006-08-31 |
2009-05-11 |
도요 세이칸 가부시키가이샤 |
핵산의 증폭방법
|
US7910354B2
(en)
|
2006-10-27 |
2011-03-22 |
Complete Genomics, Inc. |
Efficient arrays of amplified polynucleotides
|
EP2162554A4
(fr)
|
2007-05-31 |
2010-07-28 |
Univ Queensland |
Marqueurs de diagnostic pour une spondylarthrite ankylosante et leurs utilisations
|
GB0901593D0
(en)
|
2009-01-30 |
2009-03-11 |
Touchlight Genetics Ltd |
Production of closed linear DNA
|
RU2012127364A
(ru)
|
2009-11-30 |
2014-01-10 |
Квинсленд Юниверсити Оф Текнолоджи |
Химеры фибронектин: фактор роста
|
GB201013153D0
(en)
|
2010-08-04 |
2010-09-22 |
Touchlight Genetics Ltd |
Primer for production of closed linear DNA
|
WO2012019168A2
(fr)
|
2010-08-06 |
2012-02-09 |
Moderna Therapeutics, Inc. |
Acides nucléiques modifiés et leurs procédés d'utilisation
|
SG10201508149TA
(en)
|
2010-10-01 |
2015-10-29 |
Moderna Therapeutics Inc |
Engineered nucleic acids and methods of use thereof
|
DE12722942T1
(de)
|
2011-03-31 |
2021-09-30 |
Modernatx, Inc. |
Freisetzung und formulierung von manipulierten nukleinsäuren
|
US9464124B2
(en)
|
2011-09-12 |
2016-10-11 |
Moderna Therapeutics, Inc. |
Engineered nucleic acids and methods of use thereof
|
DK3682905T3
(da)
|
2011-10-03 |
2022-02-28 |
Modernatx Inc |
Modificerede nukleosider, nukleotider og nukleinsyrer og anvendelser deraf
|
CN110201187A
(zh)
|
2011-12-16 |
2019-09-06 |
现代泰克斯公司 |
经修饰的核苷、核苷酸和核酸组合物
|
EP3978030A1
(fr)
|
2012-04-02 |
2022-04-06 |
ModernaTX, Inc. |
Polynucléotides modifiés pour la production de protéines associées à une maladie humaine
|
US9572897B2
(en)
|
2012-04-02 |
2017-02-21 |
Modernatx, Inc. |
Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
|
US9254311B2
(en)
|
2012-04-02 |
2016-02-09 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of proteins
|
US9283287B2
(en)
|
2012-04-02 |
2016-03-15 |
Moderna Therapeutics, Inc. |
Modified polynucleotides for the production of nuclear proteins
|
US10174366B2
(en)
|
2012-11-14 |
2019-01-08 |
Olink Bioscience Ab |
Localised RCA-based amplification method
|
ES2921623T3
(es)
|
2012-11-26 |
2022-08-30 |
Modernatx Inc |
ARN modificado terminalmente
|
SG11201507261WA
(en)
|
2013-03-15 |
2015-10-29 |
Theranos Inc |
Nucleic acid amplification
|
US10450595B2
(en)
|
2013-03-15 |
2019-10-22 |
Theranos Ip Company, Llc |
Nucleic acid amplification
|
MX365323B
(es)
|
2013-03-15 |
2019-05-29 |
Theranos Ip Co Llc |
Amplificación de ácidos nucléicos.
|
WO2014145291A1
(fr)
*
|
2013-03-15 |
2014-09-18 |
Theranos, Inc. |
Amplification d'acide nucléique
|
US8980864B2
(en)
|
2013-03-15 |
2015-03-17 |
Moderna Therapeutics, Inc. |
Compositions and methods of altering cholesterol levels
|
WO2015034925A1
(fr)
|
2013-09-03 |
2015-03-12 |
Moderna Therapeutics, Inc. |
Polynucléotides circulaires
|
MX2018005873A
(es)
|
2013-09-06 |
2022-11-17 |
Labrador Diagnostics Llc |
Sistemas y metodos para detectar enfermedades infecciosas.
|
WO2015048744A2
(fr)
|
2013-09-30 |
2015-04-02 |
Moderna Therapeutics, Inc. |
Polynucléotides codant des polypeptides de modulation immunitaire
|
BR112016007255A2
(pt)
|
2013-10-03 |
2017-09-12 |
Moderna Therapeutics Inc |
polinucleotídeos que codificam receptor de lipoproteína de baixa densidade
|
GB201321123D0
(en)
|
2013-11-29 |
2014-01-15 |
Linea Ab Q |
Amplification of circular molecules
|
EP3256591A4
(fr)
|
2015-02-13 |
2018-08-08 |
Translate Bio Ma, Inc. |
Oligonucléotides hybrides et leurs utilisations
|
US20170151281A1
(en)
|
2015-02-19 |
2017-06-01 |
Batu Biologics, Inc. |
Chimeric antigen receptor dendritic cell (car-dc) for treatment of cancer
|
DE112016003948T5
(de)
|
2015-08-31 |
2018-05-09 |
City Of Sapporo |
Molekulare verfahren zum beurteilen einer urothelialen erkrankung
|
GB201614023D0
(en)
|
2016-08-16 |
2016-09-28 |
Olink Bioscience Ab |
Double-stranded circle probes
|
EP3558355A2
(fr)
|
2016-12-23 |
2019-10-30 |
CureVac AG |
Vaccin contre l'hénipavirus
|
EP3558354A1
(fr)
|
2016-12-23 |
2019-10-30 |
CureVac AG |
Vaccin contre le virus de lassa
|
EP3558356A2
(fr)
|
2016-12-23 |
2019-10-30 |
CureVac AG |
Vaccin contre le coronavirus du syndrome respiratoire du moyen-orient
|
CN110392577A
(zh)
|
2017-03-17 |
2019-10-29 |
库尔维科公司 |
用于组合抗癌疗法的rna疫苗和免疫检查点抑制剂
|
KR102640361B1
(ko)
|
2017-05-17 |
2024-02-23 |
마이크로바이오 피티와이 엘티디 |
바이오마커 및 그의 용도
|
EP3424524B1
(fr)
|
2017-07-04 |
2024-12-11 |
CureVac SE |
Vaccin à arn contre le cancer
|
EP3724208A4
(fr)
|
2017-12-15 |
2021-09-01 |
Flagship Pioneering Innovations VI, LLC |
Compositions comprenant des polyribonucléotides circulaires et leurs utilisations
|
EP3773702A2
(fr)
|
2018-04-05 |
2021-02-17 |
CureVac AG |
Nouvelles molécules d'acide nucléique de fièvre jaune pour la vaccination
|
WO2019202035A1
(fr)
|
2018-04-17 |
2019-10-24 |
Curevac Ag |
Nouvelles molécules d'arn rsv et compositions pour vaccination
|
US20210260178A1
(en)
|
2018-06-27 |
2021-08-26 |
Curevac Ag |
Novel lassa virus rna molecules and compositions for vaccination
|
AU2019410737A1
(en)
|
2018-12-21 |
2021-06-10 |
CureVac SE |
RNA for malaria vaccines
|
CA3125511A1
(fr)
|
2019-02-08 |
2020-08-13 |
Curevac Ag |
Arn codant administre dans l'espace suprachoroidien pour le traitement de maladies ophtalmiques
|
MA55082A
(fr)
|
2019-03-01 |
2022-01-05 |
Flagship Pioneering Innovations Vi Llc |
Compositions, procédés, et kits pour l'administration de polyribonucléotides
|
ES2928724T3
(es)
|
2019-03-01 |
2022-11-22 |
Flagship Pioneering Innovations Vi Llc |
Polirribonucleótidos y usos cosméticos de los mismos
|
KR20210135265A
(ko)
|
2019-03-04 |
2021-11-12 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
원형 폴리리보뉴클레오티드 및 그의 약제학적 조성물
|
AU2020245548A1
(en)
|
2019-03-25 |
2021-10-21 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising modified circular polyribonucleotides and uses thereof
|
JP2022537154A
(ja)
|
2019-06-14 |
2022-08-24 |
フラッグシップ パイオニアリング イノベーションズ シックス,エルエルシー |
細胞治療のための環状rna
|
US20220305128A1
(en)
|
2019-06-19 |
2022-09-29 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprising circular polyribonucleotides for protein modulation and uses thereof
|
CN114096674A
(zh)
|
2019-06-19 |
2022-02-25 |
旗舰创业创新第六有限责任公司 |
环状多核糖核苷酸的给药方法
|
AU2020328855A1
(en)
|
2019-08-14 |
2022-03-03 |
CureVac SE |
RNA combinations and compositions with decreased immunostimulatory properties
|
US10980836B1
(en)
|
2019-12-11 |
2021-04-20 |
Myeloid Therapeutics, Inc. |
Therapeutic cell compositions and methods of manufacturing and use thereof
|
TW202142239A
(zh)
|
2020-01-29 |
2021-11-16 |
美商旗艦先鋒創新有限責任公司 |
包含環狀多核糖核苷酸之組合物之遞送
|
CN115361954A
(zh)
|
2020-01-29 |
2022-11-18 |
旗舰创业创新第六有限责任公司 |
用于翻译的组合物及其使用方法
|
CA3179444A1
(fr)
|
2020-05-20 |
2021-11-25 |
Avak Kahvejian |
Compositions immunogenes et leurs utilisations
|
EP4153152A1
(fr)
|
2020-05-20 |
2023-03-29 |
Flagship Pioneering Innovations VI, LLC |
Compositions et procédés de production d'anticorps polyclonaux humains
|
CA3179420A1
(fr)
|
2020-05-20 |
2021-11-25 |
Avak Kahvejian |
Compositions d'antigenes de coronavirus et leurs utilisations
|
MX2023002439A
(es)
|
2020-09-03 |
2023-05-09 |
Flagship Pioneering Innovations Vi Llc |
Composiciones immunogénicas y usos de las mismas.
|
WO2022066757A1
(fr)
|
2020-09-23 |
2022-03-31 |
Myeloid Therapeutics, Inc. |
Procédés et compositions améliorés pour l'expression d'acides nucléiques dans des cellules
|
JP2023549140A
(ja)
|
2020-11-04 |
2023-11-22 |
マイエロイド・セラピューティクス,インコーポレーテッド |
操作されたキメラ融合タンパク質組成物およびその使用方法
|
CA3212398A1
(fr)
|
2021-03-17 |
2022-09-22 |
Daniel Getts |
Compositions de proteines de fusion chimeriques modifiees et leurs methodes d'utilisation
|
KR20240122785A
(ko)
|
2021-11-24 |
2024-08-13 |
플래그쉽 파이어니어링 이노베이션스 브이아이, 엘엘씨 |
면역원성 조성물 및 이의 용도
|
MX2024006407A
(es)
|
2021-11-24 |
2024-08-19 |
Flagship Pioneering Innovations Vi Llc |
Composiciones de inmunogenos del virus varicela-zoster y sus usos.
|
CA3239266A1
(fr)
|
2021-11-24 |
2023-06-01 |
Flagship Pioneering Innovations Vi, Llc |
Compositions immunogenes de coronavirus et leurs utilisations
|
WO2023115013A1
(fr)
|
2021-12-17 |
2023-06-22 |
Flagship Pioneering Innovations Vi, Llc |
Procédés d'enrichissement en arn circulaire dans des conditions de dénaturation
|
WO2023122745A1
(fr)
|
2021-12-22 |
2023-06-29 |
Flagship Pioneering Innovations Vi, Llc |
Compositions et procédés de purification de polyribonucléotides
|
CN118922211A
(zh)
|
2021-12-23 |
2024-11-08 |
旗舰创业创新六公司 |
编码抗融合多肽的环状多核糖核苷酸
|
WO2024097664A1
(fr)
|
2022-10-31 |
2024-05-10 |
Flagship Pioneering Innovations Vi, Llc |
Compositions et procédés de purification de polyribonucléotides
|
WO2024192422A1
(fr)
|
2023-03-15 |
2024-09-19 |
Flagship Pioneering Innovations Vi, Llc |
Compositions immunogènes et leurs utilisations
|
WO2024192420A1
(fr)
|
2023-03-15 |
2024-09-19 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprenant des polyribonucléotides et leurs utilisations
|
WO2024220712A2
(fr)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Compositions vaccinales
|
WO2024220752A2
(fr)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Compositions thérapeutiques à arn
|
WO2024220625A1
(fr)
|
2023-04-19 |
2024-10-24 |
Sail Biomedicines, Inc. |
Administration de polynucléotides à partir de nanoparticules lipidiques comprenant de l'arn et des lipides ionisables
|
WO2024226621A1
(fr)
|
2023-04-25 |
2024-10-31 |
Ginkgo Bioworks, Inc. |
Nouveau site d'entrée ribosomique interne (ires) et séquences d'introns
|
WO2024230934A1
(fr)
|
2023-05-11 |
2024-11-14 |
CureVac SE |
Acide nucléique thérapeutique pour le traitement de maladies ophtalmiques
|
WO2025006684A1
(fr)
|
2023-06-28 |
2025-01-02 |
Flagship Pioneering Innovations Vi, Llc |
Polyribonucléotides circulaires codant pour des polypeptides antifusogènes
|
WO2025042786A1
(fr)
|
2023-08-18 |
2025-02-27 |
Flagship Pioneering Innovations Vi, Llc |
Compositions comprenant des polyribonucléotides circulaires et leurs utilisations
|