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CA1204774A - Therapeutically useful alkylbenzylidene derivatives - Google Patents

Therapeutically useful alkylbenzylidene derivatives

Info

Publication number
CA1204774A
CA1204774A CA000442044A CA442044A CA1204774A CA 1204774 A CA1204774 A CA 1204774A CA 000442044 A CA000442044 A CA 000442044A CA 442044 A CA442044 A CA 442044A CA 1204774 A CA1204774 A CA 1204774A
Authority
CA
Canada
Prior art keywords
radical
general formula
hydroxy
chloro
alkaline earth
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
CA000442044A
Other languages
English (en)
French (fr)
Inventor
Jean-Pierre Kaplan
Bernard Raizon
Michel Peynot
Michel Mangane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Application granted granted Critical
Publication of CA1204774A publication Critical patent/CA1204774A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/835—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups having unsaturation outside an aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/51—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition
    • C07C45/54—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by pyrolysis, rearrangement or decomposition of compounds containing doubly bound oxygen atoms, e.g. esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/82—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups
    • C07C49/83—Ketones containing a keto group bound to a six-membered aromatic ring containing hydroxy groups polycyclic

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Anesthesiology (AREA)
  • Rheumatology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA000442044A 1982-11-29 1983-11-28 Therapeutically useful alkylbenzylidene derivatives Expired CA1204774A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8219981A FR2536746A1 (fr) 1982-11-29 1982-11-29 Derives benzylideniques alkyles, leur preparation et leur application en therapeutique
FR8219981 1982-11-29

Publications (1)

Publication Number Publication Date
CA1204774A true CA1204774A (en) 1986-05-20

Family

ID=9279618

Family Applications (1)

Application Number Title Priority Date Filing Date
CA000442044A Expired CA1204774A (en) 1982-11-29 1983-11-28 Therapeutically useful alkylbenzylidene derivatives

Country Status (22)

Country Link
JP (1) JPS59116253A (fi)
AU (1) AU2174583A (fi)
BE (1) BE898323A (fi)
CA (1) CA1204774A (fi)
CH (1) CH656876A5 (fi)
DE (1) DE3343000A1 (fi)
DK (1) DK544283D0 (fi)
ES (1) ES8406420A1 (fi)
FI (1) FI834339A (fi)
FR (1) FR2536746A1 (fi)
GB (1) GB2131024B (fi)
GR (1) GR81258B (fi)
HU (1) HU190636B (fi)
IL (1) IL70334A0 (fi)
IT (1) IT1167029B (fi)
LU (1) LU85106A1 (fi)
NL (1) NL8304070A (fi)
NO (1) NO834361L (fi)
NZ (1) NZ206409A (fi)
PT (1) PT77752B (fi)
SE (1) SE8305306L (fi)
ZA (1) ZA838862B (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2577923B1 (fr) * 1985-02-26 1988-09-09 Synthelabo Diphenylazomethines carboxylees, leur preparation et leur application

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2319338A1 (fr) * 1975-08-01 1977-02-25 Synthelabo Nouveaux derives de a- phenyl benzylideniques des acides amines, leur preparation et les medicaments qui en contiennent
FR2516509B1 (fr) * 1981-11-18 1985-07-26 Synthelabo Derives benzylideniques, leur preparation et leur application en therapeutique
PT69288A (fr) * 1978-02-27 1979-03-01 Synthelabo Procede de preparation de derives benzylideniques
FR2422628A1 (fr) * 1978-04-14 1979-11-09 Synthelabo Esters benzylideniques et leur application en therapeutique

Also Published As

Publication number Publication date
GB8331714D0 (en) 1984-01-04
HU190636B (en) 1986-09-29
DE3343000A1 (de) 1984-05-30
NL8304070A (nl) 1984-06-18
LU85106A1 (fr) 1985-07-17
SE8305306D0 (sv) 1983-09-29
IL70334A0 (en) 1984-02-29
FI834339A (fi) 1984-05-30
GB2131024B (en) 1986-02-19
AU2174583A (en) 1984-06-07
ZA838862B (en) 1984-07-25
GR81258B (fi) 1984-12-11
GB2131024A (en) 1984-06-13
FR2536746B1 (fi) 1985-03-08
NZ206409A (en) 1986-07-11
DK544283D0 (da) 1983-11-28
PT77752B (fr) 1986-06-02
IT1167029B (it) 1987-05-06
FI834339A0 (fi) 1983-11-28
FR2536746A1 (fr) 1984-06-01
BE898323A (fr) 1984-05-28
ES527584A0 (es) 1984-08-01
CH656876A5 (fr) 1986-07-31
SE8305306L (sv) 1984-05-30
ES8406420A1 (es) 1984-08-01
IT8323927A0 (it) 1983-11-28
PT77752A (fr) 1983-12-01
NO834361L (no) 1984-05-30
JPS59116253A (ja) 1984-07-05

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Legal Events

Date Code Title Description
MKEX Expiry