CA1140051A - Boric acid complexes and their use as functional preservation agents - Google Patents
Boric acid complexes and their use as functional preservation agentsInfo
- Publication number
- CA1140051A CA1140051A CA000321844A CA321844A CA1140051A CA 1140051 A CA1140051 A CA 1140051A CA 000321844 A CA000321844 A CA 000321844A CA 321844 A CA321844 A CA 321844A CA 1140051 A CA1140051 A CA 1140051A
- Authority
- CA
- Canada
- Prior art keywords
- boric acid
- complex
- urine
- samples
- bacteria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- KGBXLFKZBHKPEV-UHFFFAOYSA-N boric acid Chemical class OB(O)O KGBXLFKZBHKPEV-UHFFFAOYSA-N 0.000 title claims abstract description 95
- 238000004321 preservation Methods 0.000 title claims description 14
- 239000003795 chemical substances by application Substances 0.000 title description 7
- 239000004327 boric acid Substances 0.000 claims abstract description 85
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 54
- 238000000034 method Methods 0.000 claims abstract description 36
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 claims abstract description 21
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 19
- 239000007795 chemical reaction product Substances 0.000 claims abstract description 17
- 239000000203 mixture Substances 0.000 claims abstract description 16
- -1 polyoxy Polymers 0.000 claims abstract description 10
- 239000005715 Fructose Substances 0.000 claims abstract description 9
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 claims abstract description 9
- 229930091371 Fructose Natural products 0.000 claims abstract description 9
- FBPFZTCFMRRESA-KVTDHHQDSA-N D-Mannitol Chemical compound OC[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-KVTDHHQDSA-N 0.000 claims abstract description 8
- 229930195725 Mannitol Natural products 0.000 claims abstract description 8
- 239000000594 mannitol Substances 0.000 claims abstract description 8
- 235000010355 mannitol Nutrition 0.000 claims abstract description 8
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims abstract description 7
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims abstract description 7
- 239000000600 sorbitol Substances 0.000 claims abstract description 7
- DNIAPMSPPWPWGF-GSVOUGTGSA-N (R)-(-)-Propylene glycol Chemical compound C[C@@H](O)CO DNIAPMSPPWPWGF-GSVOUGTGSA-N 0.000 claims abstract description 4
- DNIAPMSPPWPWGF-UHFFFAOYSA-N monopropylene glycol Natural products CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 4
- 235000013772 propylene glycol Nutrition 0.000 claims abstract description 4
- 230000000087 stabilizing effect Effects 0.000 claims abstract description 4
- 239000003381 stabilizer Substances 0.000 claims abstract 2
- 210000002700 urine Anatomy 0.000 claims description 58
- 239000000654 additive Substances 0.000 claims description 15
- RBTBFTRPCNLSDE-UHFFFAOYSA-N 3,7-bis(dimethylamino)phenothiazin-5-ium Chemical compound C1=CC(N(C)C)=CC2=[S+]C3=CC(N(C)C)=CC=C3N=C21 RBTBFTRPCNLSDE-UHFFFAOYSA-N 0.000 claims description 12
- 229960000907 methylthioninium chloride Drugs 0.000 claims description 12
- 238000006243 chemical reaction Methods 0.000 claims description 11
- 230000000996 additive effect Effects 0.000 claims description 7
- 238000004040 coloring Methods 0.000 claims 3
- 239000000126 substance Substances 0.000 claims 2
- 241000894006 Bacteria Species 0.000 abstract description 42
- 150000001875 compounds Chemical class 0.000 abstract description 17
- 238000002360 preparation method Methods 0.000 abstract description 2
- 229960002645 boric acid Drugs 0.000 description 65
- 235000010338 boric acid Nutrition 0.000 description 65
- 238000012360 testing method Methods 0.000 description 23
- 239000000523 sample Substances 0.000 description 14
- 239000000243 solution Substances 0.000 description 14
- 230000032258 transport Effects 0.000 description 13
- 230000000721 bacterilogical effect Effects 0.000 description 9
- 239000000047 product Substances 0.000 description 9
- 238000005057 refrigeration Methods 0.000 description 9
- 239000003755 preservative agent Substances 0.000 description 8
- 230000002335 preservative effect Effects 0.000 description 7
- 241000588748 Klebsiella Species 0.000 description 6
- 239000002253 acid Substances 0.000 description 6
- 241000588769 Proteus <enterobacteria> Species 0.000 description 5
- PEEKVIHQOHJITP-UHFFFAOYSA-N boric acid;propane-1,2,3-triol Chemical compound OB(O)O.OCC(O)CO PEEKVIHQOHJITP-UHFFFAOYSA-N 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 239000000843 powder Substances 0.000 description 5
- 241000589516 Pseudomonas Species 0.000 description 4
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- 239000003086 colorant Substances 0.000 description 4
- 229940093476 ethylene glycol Drugs 0.000 description 4
- 238000011002 quantification Methods 0.000 description 4
- 238000005070 sampling Methods 0.000 description 4
- 230000006641 stabilisation Effects 0.000 description 4
- 238000011105 stabilization Methods 0.000 description 4
- 229920001817 Agar Polymers 0.000 description 3
- 241000588724 Escherichia coli Species 0.000 description 3
- 239000008272 agar Substances 0.000 description 3
- 239000007864 aqueous solution Substances 0.000 description 3
- 238000010438 heat treatment Methods 0.000 description 3
- 239000000376 reactant Substances 0.000 description 3
- 241000790917 Dioxys <bee> Species 0.000 description 2
- 241000219470 Mirabilis Species 0.000 description 2
- 241000589517 Pseudomonas aeruginosa Species 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- 238000013100 final test Methods 0.000 description 2
- 230000008014 freezing Effects 0.000 description 2
- 238000007710 freezing Methods 0.000 description 2
- 208000015181 infectious disease Diseases 0.000 description 2
- 238000009533 lab test Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 244000293889 Bombax malabaricum Species 0.000 description 1
- ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 description 1
- 241000375722 Cyperus eriocauloides Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 208000012868 Overgrowth Diseases 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 241000191963 Staphylococcus epidermidis Species 0.000 description 1
- 230000006978 adaptation Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000005576 amination reaction Methods 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 239000006161 blood agar Substances 0.000 description 1
- 125000005619 boric acid group Chemical group 0.000 description 1
- RERVRRLGFUNERS-UHFFFAOYSA-N boron;propane-1,2,3-triol Chemical compound [B].OCC(O)CO RERVRRLGFUNERS-UHFFFAOYSA-N 0.000 description 1
- 208000037516 chromosome inversion disease Diseases 0.000 description 1
- 229940000425 combination drug Drugs 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000000875 corresponding effect Effects 0.000 description 1
- 238000002425 crystallisation Methods 0.000 description 1
- 230000008025 crystallization Effects 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000002939 deleterious effect Effects 0.000 description 1
- 230000000881 depressing effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000004615 ingredient Substances 0.000 description 1
- 230000000977 initiatory effect Effects 0.000 description 1
- 238000011081 inoculation Methods 0.000 description 1
- 230000002452 interceptive effect Effects 0.000 description 1
- 239000002609 medium Substances 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 235000020200 pasteurised milk Nutrition 0.000 description 1
- 239000013610 patient sample Substances 0.000 description 1
- 229920005862 polyol Polymers 0.000 description 1
- 150000003077 polyols Chemical class 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000008279 sol Substances 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000004448 titration Methods 0.000 description 1
- 208000019206 urinary tract infection Diseases 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/04—Esters of boric acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Amplifiers (AREA)
- Chemical And Physical Treatments For Wood And The Like (AREA)
- Ceramic Products (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE7802147A SE419346B (sv) | 1978-02-24 | 1978-02-24 | Forfarande for stabilisering av bakteriologiska prover |
| SE7802147-4 | 1978-02-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA1140051A true CA1140051A (en) | 1983-01-25 |
Family
ID=20334100
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA000321844A Expired CA1140051A (en) | 1978-02-24 | 1979-02-16 | Boric acid complexes and their use as functional preservation agents |
Country Status (7)
| Country | Link |
|---|---|
| CA (1) | CA1140051A (no) |
| DE (1) | DE2906730C2 (no) |
| DK (1) | DK80479A (no) |
| FI (1) | FI63595C (no) |
| GB (1) | GB2016446B (no) |
| NO (1) | NO147054C (no) |
| SE (1) | SE419346B (no) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8800502D0 (en) * | 1988-01-11 | 1988-02-10 | Cerestar Holding Bv | Method of adding borax/boric acid to mixing/reaction-zone |
| US5505953A (en) | 1992-05-06 | 1996-04-09 | Alcon Laboratories, Inc. | Use of borate-polyol complexes in ophthalmic compositions |
| FR2731008B1 (fr) * | 1995-02-24 | 1999-05-07 | Dev Activites Chimiques Distri | Solution aqueuse boree, notamment pour l'adjuvantation de colle amylacee |
| WO2008131499A1 (fr) * | 2007-04-26 | 2008-11-06 | Realco Sa | Procédé de traitement de la cercosporiose du bananier et composition de traitement |
| US9102700B1 (en) * | 2014-08-29 | 2015-08-11 | Vdf Futureceuticals, Inc. | Compositions and methods for borocarbohydrate complexes |
-
1978
- 1978-02-24 SE SE7802147A patent/SE419346B/sv unknown
-
1979
- 1979-02-16 NO NO790518A patent/NO147054C/no unknown
- 1979-02-16 CA CA000321844A patent/CA1140051A/en not_active Expired
- 1979-02-19 FI FI790541A patent/FI63595C/fi not_active IP Right Cessation
- 1979-02-21 DE DE2906730A patent/DE2906730C2/de not_active Expired
- 1979-02-21 GB GB7906062A patent/GB2016446B/en not_active Expired
- 1979-02-23 DK DK80479A patent/DK80479A/da not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| DK80479A (da) | 1979-08-25 |
| SE7802147L (sv) | 1979-08-25 |
| NO147054C (no) | 1983-01-26 |
| FI63595B (fi) | 1983-03-31 |
| FI63595C (fi) | 1983-07-11 |
| GB2016446A (en) | 1979-09-26 |
| GB2016446B (en) | 1982-12-01 |
| SE419346B (sv) | 1981-07-27 |
| DE2906730A1 (de) | 1979-09-06 |
| FI790541A (fi) | 1979-08-25 |
| DE2906730C2 (de) | 1982-04-22 |
| NO790518L (no) | 1979-08-27 |
| NO147054B (no) | 1982-10-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MKEX | Expiry |