BRPI0914555A2 - derivados de triazol bicíclicos para o tratamento de tumores - Google Patents

derivados de triazol bicíclicos para o tratamento de tumores

Info

Publication number: BRPI0914555A2
Authority: BR; Brazil
Prior art keywords: tumors; treatment; triazole derivatives; bicyclic triazole; bicyclic
Prior art date: 2008-08-14

Application number

BRPI0914555A

Other languages

English (en)

Inventor

Andree Blaukat

Frank Stieber

Oliver Schadt

Original Assignee

Merck Patent Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2008-08-14

Filing date

2009-07-16

Publication date

2015-12-15

2009-07-16 Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh

2015-12-15 Publication of BRPI0914555A2 publication Critical patent/BRPI0914555A2/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Oncology (AREA)
Hematology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

BRPI0914555A 2008-08-14 2009-07-16 derivados de triazol bicíclicos para o tratamento de tumores BRPI0914555A2 (pt)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE102008037790A DE102008037790A1 (de)	2008-08-14	2008-08-14	Bicyclische Triazolderivate
PCT/EP2009/005172 WO2010017870A1 (de)	2008-08-14	2009-07-16	Bicyclische triazolderivate zur behandlung von tumoren

Publications (1)

Publication Number	Publication Date
BRPI0914555A2 true BRPI0914555A2 (pt)	2015-12-15

Family

ID=41138729

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BRPI0914555A BRPI0914555A2 (pt)	2008-08-14	2009-07-16	derivados de triazol bicíclicos para o tratamento de tumores

Country Status (16)

Country	Link
US (1)	US8435986B2 (pt)
EP (1)	EP2310013B1 (pt)
JP (1)	JP5475778B2 (pt)
KR (1)	KR20110051243A (pt)
CN (1)	CN102123710B (pt)
AR (1)	AR073055A1 (pt)
AU (1)	AU2009281491B2 (pt)
BR (1)	BRPI0914555A2 (pt)
CA (1)	CA2733941C (pt)
DE (1)	DE102008037790A1 (pt)
EA (1)	EA201100334A1 (pt)
ES (1)	ES2648233T3 (pt)
IL (1)	IL211193A0 (pt)
MX (1)	MX2011001511A (pt)
WO (1)	WO2010017870A1 (pt)
ZA (1)	ZA201101899B (pt)

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2008
- 2008-08-14 DE DE102008037790A patent/DE102008037790A1/de not_active Withdrawn
2009
- 2009-07-16 BR BRPI0914555A patent/BRPI0914555A2/pt not_active IP Right Cessation
- 2009-07-16 CA CA2733941A patent/CA2733941C/en active Active
- 2009-07-16 EP EP09777234.7A patent/EP2310013B1/de active Active
- 2009-07-16 JP JP2011522392A patent/JP5475778B2/ja active Active
- 2009-07-16 WO PCT/EP2009/005172 patent/WO2010017870A1/de active Application Filing
- 2009-07-16 CN CN2009801314380A patent/CN102123710B/zh not_active Expired - Fee Related
- 2009-07-16 ES ES09777234.7T patent/ES2648233T3/es active Active
- 2009-07-16 EA EA201100334A patent/EA201100334A1/ru unknown
- 2009-07-16 KR KR1020117005525A patent/KR20110051243A/ko not_active Withdrawn
- 2009-07-16 US US13/059,016 patent/US8435986B2/en not_active Expired - Fee Related
- 2009-07-16 MX MX2011001511A patent/MX2011001511A/es not_active Application Discontinuation
- 2009-07-16 AU AU2009281491A patent/AU2009281491B2/en not_active Ceased
- 2009-08-14 AR ARP090103142A patent/AR073055A1/es unknown
2011
- 2011-02-10 IL IL211193A patent/IL211193A0/en active IP Right Grant
- 2011-03-11 ZA ZA2011/01899A patent/ZA201101899B/en unknown

Also Published As

Publication number	Publication date
JP5475778B2 (ja)	2014-04-16
US8435986B2 (en)	2013-05-07
ES2648233T3 (es)	2017-12-29
AU2009281491A1 (en)	2010-02-18
WO2010017870A1 (de)	2010-02-18
US20110135600A1 (en)	2011-06-09
EA201100334A1 (ru)	2011-08-30
CA2733941A1 (en)	2010-02-18
AU2009281491B2 (en)	2014-02-20
CN102123710A (zh)	2011-07-13
HK1159989A1 (en)	2012-08-10
CA2733941C (en)	2016-10-04
MX2011001511A (es)	2011-03-15
ZA201101899B (en)	2011-11-30
EP2310013A1 (de)	2011-04-20
DE102008037790A1 (de)	2010-02-18
JP2011530545A (ja)	2011-12-22
EP2310013B1 (de)	2017-08-23
IL211193A0 (en)	2011-04-28
AR073055A1 (es)	2010-10-13
KR20110051243A (ko)	2011-05-17
CN102123710B (zh)	2012-11-07

Publication	Publication Date	Title
BRPI0914555A2 (pt)	2015-12-15	derivados de triazol bicíclicos para o tratamento de tumores
ZA201100534B (en)	2011-10-26	Triazole derivatives useful for the treatment of diseases
PL2303021T3 (pl)	2019-10-31	Związki do leczenia nowotworu
AP2960A (en)	2014-08-31	Substituted pyrimidines for the treatment of diseases such as cancer
IL202505A0 (en)	2010-06-30	2-oxo-3-benzyl-benzoxazol-2-one derivatives and related compounds as met kinase inhibitors for the treatment of tumors
HUE054495T2 (hu)	2021-09-28	Rák kezelésére szolgáló készítmény
SMAP200900085A (it)	2010-01-19	3-imidazolil-indoli per il trattamento di malattieproliferative
BRPI0921321A2 (pt)	2018-10-16	métodos para o tratamento de indwcções e tumores
BRPI0915105A2 (pt)	2019-09-24	composto de 2,4'-biripidinila como inibidores da proteína cinase d úteis para o tratamento de ia insuficiência cardíaca e cancer
ZA201003425B (en)	2011-04-28	5-cyano-thienopyridines for the treatment of tumors
BRPI1007995A2 (pt)	2019-09-24	orto-aminoamidas para o tratamento de cãncer.
BRPI0811103A2 (pt)	2014-12-09	Compostos triazol para tratamento de formação de biopelícula
BRPI0922884A2 (pt)	2018-11-06	compostos para tratamento de câncer
BRPI0924107A2 (pt)	2019-09-24	inibidores de hsp90 para tratamento terapêutico
IL210066A0 (en)	2011-02-28	Novel ortho-aminoanilides for the treatment of cancer
IL206189A0 (en)	2010-12-30	Compound for use in the treatment of cancer
ZA201101821B (en)	2012-01-25	1-amino-alkylcyclohexane derivatives for the treatment of inflammatory skin deases
ZA201001546B (en)	2010-10-27	Isoxazole compounds for the treatment of cancer
IL209005A0 (en)	2011-01-31	Use of corticotropin-releasing factor for the treatment of cancer
IL205339A0 (en)	2010-12-30	Compounds and methods for the treatment of cancer
HK1162949A (zh)	2012-09-07	治療癌症的組合療法
GB0604114D0 (en)	2006-04-12	Combinations for the treatment of cancer
HK1149475A (en)	2011-10-07	Use of corticotropin-releasing factor for the treatment of cancer

Legal Events

Date	Code	Title	Description
2016-09-06	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE AS 5A, 6A E 7A ANUIDADES.
2017-01-10	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: EM VIRTUDE DO ARQUIVAMENTO PUBLICADO NA RPI 2383 DE 06-09-2016 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDO O ARQUIVAMENTO DO PEDIDO DE PATENTE, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.