BRPI0708640A8 - composição farmacêutica, e, métodos para tratar um paciente com dor de cabeça de enxaqueca, para tratar um paciente com dor e para tratar um paciente com enxaqueca - Google Patents
composição farmacêutica, e, métodos para tratar um paciente com dor de cabeça de enxaqueca, para tratar um paciente com dor e para tratar um paciente com enxaquecaInfo
- Publication number
- BRPI0708640A8 BRPI0708640A8 BRPI0708640A BRPI0708640A BRPI0708640A8 BR PI0708640 A8 BRPI0708640 A8 BR PI0708640A8 BR PI0708640 A BRPI0708640 A BR PI0708640A BR PI0708640 A BRPI0708640 A BR PI0708640A BR PI0708640 A8 BRPI0708640 A8 BR PI0708640A8
- Authority
- BR
- Brazil
- Prior art keywords
- patient
- treating
- migraine
- pain
- pharmaceutical composition
- Prior art date
Links
- 208000019695 Migraine disease Diseases 0.000 title abstract 5
- 206010027599 migraine Diseases 0.000 title abstract 5
- 208000002193 Pain Diseases 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 238000010521 absorption reaction Methods 0.000 abstract 3
- 239000003814 drug Substances 0.000 abstract 3
- 239000002552 dosage form Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 abstract 2
- 238000011260 co-administration Methods 0.000 abstract 1
- 230000002496 gastric effect Effects 0.000 abstract 1
- 210000001035 gastrointestinal tract Anatomy 0.000 abstract 1
- 239000000014 opioid analgesic Substances 0.000 abstract 1
- 229940005483 opioid analgesics Drugs 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
composição farmacêutica, e, metodos para tratar um paciente com dor de cabeça de enxaqueca, para tratar um paciente com dor e para tratar um paciente com enxaqueca. a presente invenção diz respeito a formas de dosagem que podem ser usadas em métodos terapêuticos que envolvem a co-administração oral de uma combinação de pelo menos dois medicamentos, um dos quais prejudica a absorção gastrintestinal e um dos quais não prejudica. as formas de dosagem são projetadas de maneira tal que o medicamento que prejudica a absorção não é liberado no trato gastrintestinal de um paciente até que os medicamentos que não prejudicam a absorção tenham sido liberados e substancialmente absorvidos. a invenção pode ser usada no tratamento de enxaqueca usando uma combinação de triptanos e nsaids ou no tratamento de dor usando uma combinação de nsaids e analgésicos opióides.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US77937306P | 2006-03-06 | 2006-03-06 | |
US60/779373 | 2006-03-06 | ||
PCT/US2007/005266 WO2007103113A2 (en) | 2006-03-06 | 2007-03-02 | Dosage forms for administering combinations of drugs |
US11/712969 | 2007-03-02 | ||
US11/712,969 US20070207200A1 (en) | 2006-03-06 | 2007-03-02 | Dosage forms for administering combinations of drugs |
Publications (2)
Publication Number | Publication Date |
---|---|
BRPI0708640A2 BRPI0708640A2 (pt) | 2011-06-07 |
BRPI0708640A8 true BRPI0708640A8 (pt) | 2018-04-24 |
Family
ID=38471739
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0708640A BRPI0708640A8 (pt) | 2006-03-06 | 2007-03-02 | composição farmacêutica, e, métodos para tratar um paciente com dor de cabeça de enxaqueca, para tratar um paciente com dor e para tratar um paciente com enxaqueca |
Country Status (12)
Country | Link |
---|---|
US (1) | US20070207200A1 (pt) |
EP (1) | EP1993518A4 (pt) |
JP (1) | JP5349059B2 (pt) |
CN (1) | CN101410095B (pt) |
AU (1) | AU2007224229B2 (pt) |
BR (1) | BRPI0708640A8 (pt) |
CA (1) | CA2644435C (pt) |
EA (1) | EA020867B1 (pt) |
IL (1) | IL193727A (pt) |
MX (1) | MX2008011441A (pt) |
NO (1) | NO20083876L (pt) |
WO (1) | WO2007103113A2 (pt) |
Families Citing this family (47)
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US8206741B2 (en) | 2001-06-01 | 2012-06-26 | Pozen Inc. | Pharmaceutical compositions for the coordinated delivery of NSAIDs |
US20060178349A1 (en) * | 2005-01-24 | 2006-08-10 | Pozen Inc. | Compositions and therapeutic methods utilizing a combination of a 5-HT1F inhibitor and an NSAID |
WO2008074153A1 (en) | 2006-12-18 | 2008-06-26 | Electronic Dietary Foods Inc. | Device for delivery of a substance |
GB0625646D0 (en) * | 2006-12-21 | 2007-01-31 | Jagotec Ag | Improvements in or relating to organic compounds |
BRPI0700133A (pt) * | 2007-01-29 | 2008-09-16 | Incrementha P D & I Pesquisa D | composição farmacêutica compreendendo tramadol e cetoprofeno em combinação |
US20090068262A1 (en) * | 2007-04-04 | 2009-03-12 | Ilan Zalit | Rapid dissolution of combination products |
KR20100055431A (ko) * | 2007-07-20 | 2010-05-26 | 애보트 게엠베하 운트 콤파니 카게 | 비오피오이드 및 한정된 오피오이드 진통제의 제형 |
GB0714790D0 (en) * | 2007-07-30 | 2007-09-12 | Jagotec Ag | Improvements in or relating to organic compounds |
EP2203166B1 (en) * | 2007-10-16 | 2015-05-06 | Paladin Labs Inc. | Bilayer composition for the sustained release of acetaminophen and tramadol |
EP2057984B1 (de) * | 2007-11-09 | 2010-01-20 | Acino Pharma AG | Retardtabletten mit Hydromorphon |
US20090186086A1 (en) * | 2008-01-17 | 2009-07-23 | Par Pharmaceutical, Inc. | Solid multilayer oral dosage forms |
JP2011511782A (ja) | 2008-02-12 | 2011-04-14 | アボット・ラボラトリーズ | 長期放出性ヒドロコドンアセトアミノフェンならびにその関連方法および用途 |
US8372432B2 (en) | 2008-03-11 | 2013-02-12 | Depomed, Inc. | Gastric retentive extended-release dosage forms comprising combinations of a non-opioid analgesic and an opioid analgesic |
CN102105136B (zh) | 2008-03-11 | 2014-11-26 | 蒂宝制药公司 | 包含非-阿片类止痛剂和阿片类止痛剂的组合的胃滞留型缓释剂型 |
US20090252791A1 (en) * | 2008-04-02 | 2009-10-08 | Venkata Nookaraju Sreedharala | Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug |
AU2013202680C1 (en) * | 2008-04-28 | 2016-06-23 | Zogenix, Inc. | Novel formulations for treatment of migraine |
EP3000462A1 (en) | 2008-04-28 | 2016-03-30 | Zogenix, Inc. | Novel formulations for treatment of migraine |
CA2765866C (en) * | 2008-06-20 | 2016-06-21 | Alphapharm Pty Ltd | Single phase pharmaceutical composition of a 5-ht1 inhibitor and an nsaid |
US20100008986A1 (en) * | 2008-07-14 | 2010-01-14 | Glenmark Generics, Ltd. | Pharmaceutical compositions comprising sumatriptan and naproxen |
MX2011002515A (es) | 2008-09-09 | 2011-04-07 | Astrazeneca Ab | Metodo de administracion de una composicion farmaceutica a un paciente que lo necesita. |
SG176724A1 (en) | 2009-06-25 | 2012-01-30 | Astrazeneca Ab | Method for treating a patient at risk for developing an nsaid-associated ulcer |
WO2011087765A2 (en) * | 2009-12-22 | 2011-07-21 | Mallinckrodt Inc. | Methods of producing stabilized solid pharmaceutical compositions containing morphinans |
US9198861B2 (en) | 2009-12-22 | 2015-12-01 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
US20110150989A1 (en) * | 2009-12-22 | 2011-06-23 | Mallinkckrodt Inc. | Methods of Producing Stabilized Solid Dosage Pharmaceutical Compositions Containing Morphinans |
US8597681B2 (en) | 2009-12-22 | 2013-12-03 | Mallinckrodt Llc | Methods of producing stabilized solid dosage pharmaceutical compositions containing morphinans |
AR082167A1 (es) * | 2010-07-14 | 2012-11-14 | Gruenenthal Gmbh | Formas de dosificacion gastrorretentivas |
CN101987092A (zh) * | 2010-09-27 | 2011-03-23 | 苏州世林医药技术发展有限公司 | 含有镇痛剂的新型药学组成物 |
US8741885B1 (en) | 2011-05-17 | 2014-06-03 | Mallinckrodt Llc | Gastric retentive extended release pharmaceutical compositions |
US8858963B1 (en) | 2011-05-17 | 2014-10-14 | Mallinckrodt Llc | Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia |
US8658631B1 (en) | 2011-05-17 | 2014-02-25 | Mallinckrodt Llc | Combination composition comprising oxycodone and acetaminophen for rapid onset and extended duration of analgesia |
US10525054B2 (en) | 2011-11-07 | 2020-01-07 | Inheris Biopharma, Inc. | Compositions, dosage forms, and co-administration of an opioid agonist compound and an analgesic compound |
JP6593993B2 (ja) * | 2011-11-07 | 2019-10-23 | ネクター セラピューティクス | オピオイドアゴニスト化合物と鎮痛性化合物との組成物、剤形、および同時投与 |
UA115139C2 (uk) | 2011-12-28 | 2017-09-25 | Поузен Інк. | Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту |
CN103385876B (zh) * | 2012-05-08 | 2016-01-13 | 四川滇虹医药开发有限公司 | 一种夫罗曲坦的药物组合物及其制备方法 |
MX2013008995A (es) * | 2013-08-02 | 2014-03-24 | Raam De Sahuayo S A De C V Lab | Composicion farmaceutica para el tratamiento del dolor. |
MX362435B (es) * | 2013-08-02 | 2019-01-17 | Laboratorio Raam De Sahuayo S A De C V | Novedoso sistema farmaceutico de entrega bifasica para el tratamiento del dolor y la inflamacion. |
WO2015023675A2 (en) | 2013-08-12 | 2015-02-19 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded immediate release abuse deterrent pill |
CN104434918A (zh) * | 2013-09-16 | 2015-03-25 | 江苏恩华药业股份有限公司 | 盐酸羟考酮与布洛芬复方多层片及其制备方法 |
US9492444B2 (en) | 2013-12-17 | 2016-11-15 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US10172797B2 (en) | 2013-12-17 | 2019-01-08 | Pharmaceutical Manufacturing Research Services, Inc. | Extruded extended release abuse deterrent pill |
US20150209360A1 (en) * | 2014-01-30 | 2015-07-30 | Orbz, Llc | Oral caffeine delivery composition |
AU2015290098B2 (en) | 2014-07-17 | 2018-11-01 | Pharmaceutical Manufacturing Research Services, Inc. | Immediate release abuse deterrent liquid fill dosage form |
ES2806426T3 (es) * | 2014-10-08 | 2021-02-17 | Synthetic Biologics Inc | Formulaciones de betalactamasas y usos de las mismas |
JP2017531026A (ja) | 2014-10-20 | 2017-10-19 | ファーマシューティカル マニュファクチュアリング リサーチ サービシズ,インコーポレーテッド | 徐放性乱用抑止性液体充填剤形 |
CN104523709A (zh) * | 2014-12-22 | 2015-04-22 | 青岛正大海尔制药有限公司 | 一种含有琥珀酸夫罗曲坦的复方缓释制剂 |
KR101710792B1 (ko) * | 2015-07-14 | 2017-02-28 | 주식회사 유영제약 | 세레콕시브 및 트라마돌을 함유하는 약제학적 조성물 |
CN109700816B (zh) * | 2018-12-29 | 2020-10-16 | 南通励成生物工程有限公司 | 磷脂酰丝氨酸肠溶包衣制剂及其制备方法 |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8521350D0 (en) * | 1985-08-28 | 1985-10-02 | Euro Celtique Sa | Analgesic composition |
ES2106818T3 (es) * | 1991-10-30 | 1997-11-16 | Glaxo Group Ltd | Composicion multicapa que contiene antagonistas de histamina o secotina. |
GB9407386D0 (en) * | 1994-04-14 | 1994-06-08 | Smithkline Beecham Plc | Pharmaceutical formulation |
DE19601477C2 (de) * | 1996-01-17 | 1999-12-16 | Axel Kirsch | Befestigungsnagel |
US6077539A (en) * | 1996-11-12 | 2000-06-20 | Pozen, Inc. | Treatment of migraine headache |
DE19710008A1 (de) * | 1997-03-12 | 1998-09-17 | Basf Ag | Feste, mindestens zweiphasige Zubereitungsformen eines Opioid-Analgeticums mit verzögerter Freisetzung |
EA002806B1 (ru) * | 1997-09-11 | 2002-10-31 | Нюкомед Данмарк А/С | Многоединичные композиции с модифицированным высвобождением нестероидных противовоспалительных лекарственных веществ (nsaid) |
DE19901687B4 (de) * | 1999-01-18 | 2006-06-01 | Grünenthal GmbH | Opioide Analgetika mit kontrollierter Wirkstofffreisetzung |
WO2004039361A1 (en) * | 2002-10-25 | 2004-05-13 | Collegium Pharmaceutical, Inc. | Pulsatile release compositions of milnacipran |
WO2004060355A1 (en) * | 2002-12-26 | 2004-07-22 | Pozen Inc. | Multilayer Dosage Forms Containing NSAIDs and Triptans |
AU2004247076A1 (en) * | 2003-06-06 | 2004-12-23 | Glaxo Group Limited | Composition comprising triptans and NSAIDs |
AU2004246837B2 (en) * | 2003-06-06 | 2009-07-16 | Ethypharm | Orally-dispersible multilayer tablet |
FR2855756B1 (fr) * | 2003-06-06 | 2005-08-26 | Ethypharm Sa | Comprime orodispersible multicouche |
CA2575006A1 (en) * | 2004-07-26 | 2006-02-02 | E. Itzhak Lerner | Dosage forms with an enterically coated core tablet |
-
2007
- 2007-03-02 JP JP2008558308A patent/JP5349059B2/ja not_active Expired - Fee Related
- 2007-03-02 CA CA2644435A patent/CA2644435C/en not_active Expired - Fee Related
- 2007-03-02 MX MX2008011441A patent/MX2008011441A/es active IP Right Grant
- 2007-03-02 EA EA200870325A patent/EA020867B1/ru not_active IP Right Cessation
- 2007-03-02 WO PCT/US2007/005266 patent/WO2007103113A2/en active Application Filing
- 2007-03-02 BR BRPI0708640A patent/BRPI0708640A8/pt not_active Application Discontinuation
- 2007-03-02 CN CN200780011121.4A patent/CN101410095B/zh not_active Expired - Fee Related
- 2007-03-02 AU AU2007224229A patent/AU2007224229B2/en not_active Ceased
- 2007-03-02 EP EP07751994A patent/EP1993518A4/en not_active Withdrawn
- 2007-03-02 US US11/712,969 patent/US20070207200A1/en not_active Abandoned
-
2008
- 2008-08-27 IL IL193727A patent/IL193727A/en not_active IP Right Cessation
- 2008-09-10 NO NO20083876A patent/NO20083876L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
US20070207200A1 (en) | 2007-09-06 |
CN101410095B (zh) | 2015-07-01 |
EA020867B1 (ru) | 2015-02-27 |
BRPI0708640A2 (pt) | 2011-06-07 |
AU2007224229A1 (en) | 2007-09-13 |
WO2007103113A3 (en) | 2007-11-01 |
NO20083876L (no) | 2008-12-02 |
HK1128230A1 (en) | 2009-10-23 |
JP2009539761A (ja) | 2009-11-19 |
EA200870325A1 (ru) | 2009-02-27 |
IL193727A (en) | 2015-07-30 |
EP1993518A2 (en) | 2008-11-26 |
CN101410095A (zh) | 2009-04-15 |
IL193727A0 (en) | 2009-05-04 |
WO2007103113A2 (en) | 2007-09-13 |
CA2644435A1 (en) | 2007-09-13 |
EP1993518A4 (en) | 2012-12-12 |
CA2644435C (en) | 2015-04-07 |
AU2007224229B2 (en) | 2012-10-11 |
JP5349059B2 (ja) | 2013-11-20 |
MX2008011441A (es) | 2008-11-18 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B07D | Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette] | ||
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B07E | Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette] |
Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI |
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B06T | Formal requirements before examination [chapter 6.20 patent gazette] | ||
B11E | Dismissal acc. art. 34 of ipl - requirements for examination incomplete | ||
B11T | Dismissal of application maintained [chapter 11.20 patent gazette] |