BRPI0510315A - integração de vacinação com conjugado meningocócico - Google Patents
integração de vacinação com conjugado meningocócicoInfo
- Publication number
- BRPI0510315A BRPI0510315A BRPI0510315-0A BRPI0510315A BRPI0510315A BR PI0510315 A BRPI0510315 A BR PI0510315A BR PI0510315 A BRPI0510315 A BR PI0510315A BR PI0510315 A BRPI0510315 A BR PI0510315A
- Authority
- BR
- Brazil
- Prior art keywords
- carrier protein
- patient
- diphtheria toxoid
- meningococcal
- conjugates
- Prior art date
Links
- 230000010354 integration Effects 0.000 title 1
- 238000002255 vaccination Methods 0.000 title 1
- 102000014914 Carrier Proteins Human genes 0.000 abstract 4
- 108010078791 Carrier Proteins Proteins 0.000 abstract 4
- 150000001720 carbohydrates Chemical class 0.000 abstract 3
- 229960003983 diphtheria toxoid Drugs 0.000 abstract 3
- 108010071134 CRM197 (non-toxic variant of diphtheria toxin) Proteins 0.000 abstract 1
- 229940032024 DPT vaccine Drugs 0.000 abstract 1
- 229960004443 hemophilus influenzae b vaccines Drugs 0.000 abstract 1
- 238000002649 immunization Methods 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229940031999 pneumococcal conjugate vaccine Drugs 0.000 abstract 1
- 230000001629 suppression Effects 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/646—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the entire peptide or protein drug conjugate elicits an immune response, e.g. conjugate vaccines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
INTEGRAçãO DE VACINAçãO COM CONJUGADO MENINGOCóCICO. A invenção proporciona um método para imunização de um paciente compreendendo administração de conjugados múltiplos de sacarídeos capsulares meningocócicos, em que cada conjugado compreende uma proteína veículo de toxóide de difteria (ou derivado do mesmo) e o sacarídeo capsular e em que o paciente foi pré-imunizado com um toxóide de difteria (ou derivado do mesmo).
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0409750A GB0409750D0 (en) | 2004-04-30 | 2004-04-30 | Integration of meningococcal conjugate vaccination |
GBGB0500787.7A GB0500787D0 (en) | 2005-01-14 | 2005-01-14 | Integration of meningococcal conjugate vaccination |
PCT/GB2005/001653 WO2005105140A2 (en) | 2004-04-30 | 2005-04-29 | Meningococcal conjugate vaccination |
Publications (1)
Publication Number | Publication Date |
---|---|
BRPI0510315A true BRPI0510315A (pt) | 2007-10-16 |
Family
ID=35057184
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0510315-0A BRPI0510315A (pt) | 2004-04-30 | 2005-04-29 | integração de vacinação com conjugado meningocócico |
Country Status (15)
Country | Link |
---|---|
US (2) | US9402915B2 (pt) |
EP (2) | EP2272531A3 (pt) |
JP (2) | JP5718545B2 (pt) |
AT (1) | ATE512670T1 (pt) |
AU (1) | AU2005237289B2 (pt) |
BR (1) | BRPI0510315A (pt) |
CY (1) | CY1111814T1 (pt) |
DK (1) | DK1740217T3 (pt) |
MX (1) | MXPA06011994A (pt) |
NZ (1) | NZ550533A (pt) |
PL (1) | PL1740217T3 (pt) |
PT (1) | PT1740217E (pt) |
RU (1) | RU2379052C2 (pt) |
SI (1) | SI1740217T1 (pt) |
WO (1) | WO2005105140A2 (pt) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MX339524B (es) | 2001-10-11 | 2016-05-30 | Wyeth Corp | Composiciones inmunogenicas novedosas para la prevencion y tratamiento de enfermedad meningococica. |
DK1740217T3 (da) | 2004-04-30 | 2011-09-26 | Novartis Ag | Meningokok-konjugat-vaccination |
GB0500787D0 (en) * | 2005-01-14 | 2005-02-23 | Chiron Srl | Integration of meningococcal conjugate vaccination |
US9789179B2 (en) | 2005-06-27 | 2017-10-17 | Glaxosmithkline Biologicals S.A. | Immunogenic composition |
MX2008008140A (es) | 2005-12-22 | 2008-09-24 | Glaxosmithkline Biolog Sa | Vacuna que comprende conjugados de polisacarido capsular de streptococcus pneumonia. |
TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
ATE554788T1 (de) | 2006-03-22 | 2012-05-15 | Novartis Ag | Schemata zur immunisierung mit meningokokken- konjugaten |
AR064642A1 (es) | 2006-12-22 | 2009-04-15 | Wyeth Corp | Polinucleotido vector que lo comprende celula recombinante que comprende el vector polipeptido , anticuerpo , composicion que comprende el polinucleotido , vector , celula recombinante polipeptido o anticuerpo , uso de la composicion y metodo para preparar la composicion misma y preparar una composi |
CN101265288B (zh) * | 2007-03-13 | 2012-03-21 | 齐鲁制药有限公司 | Crm197突变体的纯化方法 |
CN101314619B (zh) * | 2007-06-01 | 2010-12-22 | 齐鲁制药有限公司 | 肿瘤治疗性疫苗ctp37crm197免疫原及其制备方法与应用 |
JP2010531330A (ja) | 2007-06-26 | 2010-09-24 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | 肺炎連鎖球菌莢膜多糖コンジュゲートを含むワクチン |
SI2608805T1 (sl) | 2010-08-23 | 2017-08-31 | Wyeth Llc | Stabilne formulacije antigenov rLP2086 neisserie meningitidis |
BR112013005329A2 (pt) | 2010-09-10 | 2017-05-02 | Wyeth Llc | variantes não lipidadas de antígenos orf2086 de neisseria meningitidis |
KR101895768B1 (ko) | 2011-06-01 | 2018-09-07 | 시아먼 유니버시티 | 디프테리아 독소 무독성 돌연변이 씨알엠197 또는 그의 단편을 포함하는 융합 단백질 |
CA2960030C (en) | 2012-03-09 | 2020-02-25 | Pfizer Inc. | Neisseria meningitidis compositions and methods thereof |
SA115360586B1 (ar) | 2012-03-09 | 2017-04-12 | فايزر انك | تركيبات لعلاج الالتهاب السحائي البكتيري وطرق لتحضيرها |
US20150273036A1 (en) * | 2012-10-12 | 2015-10-01 | Glaxosmithkline Biologicals Sa | Non-cross-linked acellular pertussis antigens for use in combination vaccines |
EP2964665B1 (en) | 2013-03-08 | 2018-08-01 | Pfizer Inc | Immunogenic fusion polypeptides |
RU2662968C2 (ru) | 2013-09-08 | 2018-07-31 | Пфайзер Инк. | Иммуногенная композиция против neisseria meningitidis (варианты) |
CN107249626A (zh) | 2015-02-19 | 2017-10-13 | 辉瑞大药厂 | 脑膜炎奈瑟球菌组合物及其方法 |
HRP20240433T1 (hr) | 2016-09-02 | 2024-07-05 | Sanofi Pasteur, Inc. | Cjepivo protiv neisseria meningitidis |
MX372587B (es) | 2017-01-31 | 2020-04-17 | Pfizer | Composiciones de neisseria meningitidis y metodos respectivos |
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EP1490409B1 (en) | 2002-03-26 | 2008-12-31 | Novartis Vaccines and Diagnostics S.r.l. | Modified saccharides having improved stability in water |
ATE513560T1 (de) | 2002-05-14 | 2011-07-15 | Novartis Vaccines & Diagnostic | Kombinationsimpfstoff gegen bakterielle meningitis, der über die schleimhaut appliziert wird |
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-
2005
- 2005-04-29 DK DK05738559.3T patent/DK1740217T3/da active
- 2005-04-29 JP JP2007510120A patent/JP5718545B2/ja not_active Expired - Lifetime
- 2005-04-29 EP EP10179765A patent/EP2272531A3/en not_active Withdrawn
- 2005-04-29 EP EP05738559A patent/EP1740217B1/en not_active Revoked
- 2005-04-29 AU AU2005237289A patent/AU2005237289B2/en not_active Expired
- 2005-04-29 RU RU2006142158/14A patent/RU2379052C2/ru active
- 2005-04-29 BR BRPI0510315-0A patent/BRPI0510315A/pt not_active Application Discontinuation
- 2005-04-29 SI SI200531349T patent/SI1740217T1/sl unknown
- 2005-04-29 US US11/587,170 patent/US9402915B2/en active Active
- 2005-04-29 MX MXPA06011994A patent/MXPA06011994A/es active IP Right Grant
- 2005-04-29 PT PT05738559T patent/PT1740217E/pt unknown
- 2005-04-29 NZ NZ550533A patent/NZ550533A/en not_active IP Right Cessation
- 2005-04-29 AT AT05738559T patent/ATE512670T1/de active
- 2005-04-29 WO PCT/GB2005/001653 patent/WO2005105140A2/en active Application Filing
- 2005-04-29 PL PL05738559T patent/PL1740217T3/pl unknown
-
2011
- 2011-09-08 CY CY20111100866T patent/CY1111814T1/el unknown
-
2013
- 2013-03-15 JP JP2013052745A patent/JP2013116915A/ja active Pending
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2016
- 2016-06-29 US US15/197,376 patent/US10064932B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1740217B1 (en) | 2011-06-15 |
NZ550533A (en) | 2010-02-26 |
EP2272531A2 (en) | 2011-01-12 |
SI1740217T1 (sl) | 2011-10-28 |
EP2272531A3 (en) | 2011-04-13 |
US9402915B2 (en) | 2016-08-02 |
AU2005237289B2 (en) | 2011-08-04 |
AU2005237289A1 (en) | 2005-11-10 |
PL1740217T3 (pl) | 2012-03-30 |
US20160303215A1 (en) | 2016-10-20 |
JP5718545B2 (ja) | 2015-05-13 |
ATE512670T1 (de) | 2011-07-15 |
DK1740217T3 (da) | 2011-09-26 |
JP2007535527A (ja) | 2007-12-06 |
PT1740217E (pt) | 2011-08-02 |
MXPA06011994A (es) | 2007-01-25 |
WO2005105140A3 (en) | 2006-01-19 |
US20090060945A1 (en) | 2009-03-05 |
WO2005105140A2 (en) | 2005-11-10 |
JP2013116915A (ja) | 2013-06-13 |
RU2379052C2 (ru) | 2010-01-20 |
EP1740217A2 (en) | 2007-01-10 |
CY1111814T1 (el) | 2015-10-07 |
US10064932B2 (en) | 2018-09-04 |
RU2006142158A (ru) | 2008-06-20 |
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