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BRPI0417992B8 - métodos para purificar fsh humano recombinante ou uma variante de fsh - Google Patents

métodos para purificar fsh humano recombinante ou uma variante de fsh

Info

Publication number
BRPI0417992B8
BRPI0417992B8 BRPI0417992A BRPI0417992A BRPI0417992B8 BR PI0417992 B8 BRPI0417992 B8 BR PI0417992B8 BR PI0417992 A BRPI0417992 A BR PI0417992A BR PI0417992 A BRPI0417992 A BR PI0417992A BR PI0417992 B8 BRPI0417992 B8 BR PI0417992B8
Authority
BR
Brazil
Prior art keywords
fsh
methods
recombinant human
purifying recombinant
variant
Prior art date
Application number
BRPI0417992A
Other languages
English (en)
Inventor
Rossi Mara
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of BRPI0417992A publication Critical patent/BRPI0417992A/pt
Publication of BRPI0417992B1 publication Critical patent/BRPI0417992B1/pt
Publication of BRPI0417992B8 publication Critical patent/BRPI0417992B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Reproductive Health (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Fats And Perfumes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Fluid-Pressure Circuits (AREA)
  • Manufacturing Of Electric Cables (AREA)

Abstract

método para purificar fsh. a presente invenção refere-se a um método para purificar fsh recombinante.
BRPI0417992A 2003-12-22 2004-12-16 métodos para purificar fsh humano recombinante ou uma variante de fsh BRPI0417992B8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP03104925 2003-12-22
PCT/EP2004/014347 WO2005063811A1 (en) 2003-12-22 2004-12-16 Method for purifying fsh

Publications (3)

Publication Number Publication Date
BRPI0417992A BRPI0417992A (pt) 2007-04-27
BRPI0417992B1 BRPI0417992B1 (pt) 2019-01-02
BRPI0417992B8 true BRPI0417992B8 (pt) 2021-05-25

Family

ID=34717242

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0417992A BRPI0417992B8 (pt) 2003-12-22 2004-12-16 métodos para purificar fsh humano recombinante ou uma variante de fsh

Country Status (17)

Country Link
US (1) US7754860B2 (pt)
EP (1) EP1697412B1 (pt)
JP (1) JP4763616B2 (pt)
KR (1) KR101160985B1 (pt)
CN (1) CN100554277C (pt)
AT (1) ATE446314T1 (pt)
AU (1) AU2004309040B2 (pt)
BR (1) BRPI0417992B8 (pt)
CA (1) CA2544333A1 (pt)
DE (1) DE602004023757D1 (pt)
EA (1) EA008924B1 (pt)
ES (1) ES2333128T3 (pt)
HK (1) HK1099031A1 (pt)
IL (1) IL176328A (pt)
NO (1) NO330774B1 (pt)
UA (1) UA90664C2 (pt)
WO (1) WO2005063811A1 (pt)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2005303818B2 (en) 2004-11-09 2011-06-23 Ares Trading S.A. Method for purifying FSH
DK1917276T3 (en) * 2005-08-26 2018-05-07 Ares Trading Sa Process for Preparation of Glycosylated Interferon Beta
CA2625978A1 (en) * 2005-12-09 2007-06-14 Ares Trading S.A. Method for purifying fsh or a fsh mutant
DK2170942T3 (da) 2007-06-28 2013-11-04 Biogenerix Ag Fsh-producerende celleklon
AU2008314687A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying Fc-fusion proteins
CA2701221A1 (en) * 2007-10-22 2009-04-30 Merck Serono S.A. Method for purifying an fc-containing protein
CA2711375C (en) 2008-01-18 2019-04-16 F. Hoffmann-La Roche Ag Purification of not-glycosylated polypeptides
PL2249869T3 (pl) 2008-02-08 2012-02-29 Theramex Hq Uk Ltd Ciekły preparat FSH
JP2009273427A (ja) 2008-05-16 2009-11-26 Jcr Pharmaceuticals Co Ltd 組換え体ヒトｆｓｈの製造方法
HUE025959T2 (en) 2009-04-01 2016-05-30 Ratiopharm Gmbh A method for purifying recombinant FSH
CN101555279B (zh) * 2009-05-19 2013-03-27 上海天伟生物制药有限公司 一种高纯度尿促卵泡刺激素及其制备方法
EP2325194A1 (en) * 2009-11-24 2011-05-25 Glycotope GmbH Process for the purification of glycoproteins
CN101948529B (zh) * 2010-08-13 2013-05-01 中国科学院过程工程研究所 一种高效纯化金属离子结合蛋白的疏水层析分离纯化方法
CN103570820B (zh) * 2012-08-06 2015-11-18 齐鲁制药有限公司 一种重组人促卵泡激素的纯化方法
US20160024181A1 (en) 2013-03-13 2016-01-28 Moderna Therapeutics, Inc. Long-lived polynucleotide molecules
BR112015028737B1 (pt) * 2013-05-16 2022-05-10 Universidade De São Paulo - Usp Métodos para a produção e/ou purificação de hormônios
MX2016013416A (es) * 2014-04-18 2017-01-18 Cadila Healthcare Ltd Nuevo proceso de purificacion de gonadotropina.
CN104961821A (zh) * 2014-07-28 2015-10-07 厦门欧瑞捷生物科技有限公司 一种从人尿中提取促性腺激素的方法
KR102752764B1 (ko) * 2019-12-26 2025-01-14 주식회사 엘지화학 여포 자극 호르몬의 정제 방법
CN116143901B (zh) * 2022-11-28 2024-08-02 景泽生物医药(合肥)股份有限公司 一种促卵泡激素的纯化方法
KR20240106989A (ko) * 2022-12-29 2024-07-08 주식회사 엘지화학 난포자극호르몬(fsh)의 단일 글리코실화된 형태의 함량 분석 방법
CN118063586A (zh) * 2024-04-03 2024-05-24 独步吾奇生物医疗科技(江苏)有限公司 一种人碱性成纤维细胞生长因子的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1206302B (it) * 1987-06-26 1989-04-14 Serono Cesare Ist Ricerca Ormone follicolo-stimolante urinario
CA2044717A1 (en) * 1990-06-18 1991-12-19 Candadai S. Ramadoss Process for the separation of proteins, polypeptides or metals
EP0475779A1 (en) * 1990-09-14 1992-03-18 Vittal Mallya Scientific Research Foundation Process for the separation of proteins, polypeptides or metals using immobilized, optionally modified, phosvitin
US6162905A (en) * 1996-11-07 2000-12-19 Ibsa Institut Biochimique S.A. FSH and LH separation and purification process
US6414123B1 (en) * 1997-10-21 2002-07-02 Vitro Diagnostics, Inc. Method for purifying FSH
ES2284494T3 (es) * 1999-04-16 2007-11-16 Instituto Massone S.A. Procedimiento para preparar composiciones de gonadotropina.
KR100808149B1 (ko) * 2000-02-22 2008-02-29 라보라토리스 세로노 에스.에이. 정제된 ｌｈ
AU2005303818B2 (en) 2004-11-09 2011-06-23 Ares Trading S.A. Method for purifying FSH

Also Published As

Publication number Publication date
CN100554277C (zh) 2009-10-28
DE602004023757D1 (de) 2009-12-03
JP2008500273A (ja) 2008-01-10
US7754860B2 (en) 2010-07-13
BRPI0417992A (pt) 2007-04-27
ATE446314T1 (de) 2009-11-15
CA2544333A1 (en) 2005-07-14
CN1890265A (zh) 2007-01-03
EA200601029A1 (ru) 2006-10-27
EA008924B1 (ru) 2007-08-31
US20070129295A1 (en) 2007-06-07
IL176328A0 (en) 2006-10-05
JP4763616B2 (ja) 2011-08-31
WO2005063811A1 (en) 2005-07-14
AU2004309040B2 (en) 2010-12-16
NO330774B1 (no) 2011-07-11
ES2333128T3 (es) 2010-02-17
BRPI0417992B1 (pt) 2019-01-02
NO20063304L (no) 2006-07-17
KR101160985B1 (ko) 2012-06-29
IL176328A (en) 2013-04-30
AU2004309040A1 (en) 2005-07-14
HK1099031A1 (en) 2007-08-03
KR20060135656A (ko) 2006-12-29
EP1697412A1 (en) 2006-09-06
EP1697412B1 (en) 2009-10-21
UA90664C2 (ru) 2010-05-25

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 02/01/2019, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 16/12/2004 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF