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BRPI0414781A - aminoácidos com afinidade para a proteìna (alfa)2(delta) - Google Patents

aminoácidos com afinidade para a proteìna (alfa)2(delta)

Info

Publication number
BRPI0414781A
BRPI0414781A BRPI0414781-2A BRPI0414781A BRPI0414781A BR PI0414781 A BRPI0414781 A BR PI0414781A BR PI0414781 A BRPI0414781 A BR PI0414781A BR PI0414781 A BRPI0414781 A BR PI0414781A
Authority
BR
Brazil
Prior art keywords
amino acids
delta
alpha
protein
affinity amino
Prior art date
Application number
BRPI0414781-2A
Other languages
English (en)
Inventor
Christopher James Deur
Christine Nylund Kolz
Augustine Tobi Osuma
Mark Stephen Plummer
Jacob Bradley Schwarz
Andrew John Thorpe
David Juergen Wustrow
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34396281&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0414781(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of BRPI0414781A publication Critical patent/BRPI0414781A/pt

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    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/06—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton
    • C07C229/08—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one amino and one carboxyl group bound to the carbon skeleton the nitrogen atom of the amino group being further bound to hydrogen atoms
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • C07C229/20—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups
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    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/34—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton containing six-membered aromatic rings
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    • C07D263/18—Oxygen atoms
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Abstract

"AMINOáCIDOS COM AFINIDADE PARA A PROTEìNA <244>2<SYM>". São revelados certos <225>-aminoácidos que se ligam à subunidade alfa-2-delta (<244>2S) de um canal de cálcio. Estes compostos e os seus sais farmaceuticamente aceitáveis são úteis no tratamento de uma variedade de distúrbios psiquiátricos, de dor e outros.
BRPI0414781-2A 2003-09-25 2004-09-13 aminoácidos com afinidade para a proteìna (alfa)2(delta) BRPI0414781A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US50595303P 2003-09-25 2003-09-25
US50744303P 2003-09-30 2003-09-30
PCT/IB2004/002985 WO2005030700A2 (en) 2003-09-25 2004-09-13 Amino acids with affinity for the alpha2delta-protein

Publications (1)

Publication Number Publication Date
BRPI0414781A true BRPI0414781A (pt) 2006-11-21

Family

ID=34396281

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0414781-2A BRPI0414781A (pt) 2003-09-25 2004-09-13 aminoácidos com afinidade para a proteìna (alfa)2(delta)

Country Status (27)

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US (3) US20050124668A1 (pt)
EP (1) EP1667957A2 (pt)
JP (2) JP4001349B2 (pt)
KR (2) KR100768974B1 (pt)
AP (1) AP2006003544A0 (pt)
AR (1) AR046022A1 (pt)
AU (1) AU2004276072A1 (pt)
BR (1) BRPI0414781A (pt)
CA (1) CA2540208A1 (pt)
CO (1) CO5680413A2 (pt)
CR (1) CR8290A (pt)
EA (1) EA200600467A1 (pt)
EC (1) ECSP066450A (pt)
IL (1) IL173764A0 (pt)
IS (1) IS8308A (pt)
MA (1) MA28048A1 (pt)
MX (1) MXPA06003395A (pt)
NL (2) NL1027115C2 (pt)
NO (1) NO20061812L (pt)
OA (1) OA13258A (pt)
PA (1) PA8613101A1 (pt)
PE (1) PE20050434A1 (pt)
RS (1) RS20060210A (pt)
TN (1) TNSN06095A1 (pt)
TW (1) TW200528420A (pt)
UY (1) UY28533A1 (pt)
WO (1) WO2005030700A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA06014662A (es) * 2004-07-09 2007-02-12 Warner Lambert Co Preparacion de beta-amino acidos que tienen afinidad por la proteina alfa-2-delta.
US20080194841A1 (en) * 2005-03-24 2008-08-14 Pfizer Inc. Preparation of Optically Pure Beta-Amino Acids Having Affinity for the Alpha-Delta Protein
EP1954260A2 (en) * 2005-11-17 2008-08-13 Pfizer Limited Isocystene derivatives for the treatment of pain
CA2640402C (en) * 2006-03-06 2012-01-03 Pfizer Products Inc. Alpha-2-delta ligands for non-restorative sleep
AR061728A1 (es) * 2006-06-30 2008-09-17 Pfizer Prod Inc Composicion para tratamiento usando compuestos selectivos alfa-2-delta-1
EP1903027A1 (en) 2006-09-13 2008-03-26 Novartis AG Process for preparing biaryl substituted 4-amino-butyric acid or derivatives thereof and their use in the production of NEP inhibitors
US20110130454A1 (en) * 2009-11-24 2011-06-02 Xenoport, Inc. Prodrugs of gamma-amino acid, alpha-2-delta ligands, pharmaceutical compositions and uses thereof
US20110124705A1 (en) * 2009-11-24 2011-05-26 Xenoport, Inc. Prodrugs of alpha-2-delta ligands, pharmaceutical compositions and uses thereof
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