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BR9808016A - Composições e métodos para redução da hipertensão ocular - Google Patents

Composições e métodos para redução da hipertensão ocular

Info

Publication number
BR9808016A
BR9808016A BR9808016-4A BR9808016A BR9808016A BR 9808016 A BR9808016 A BR 9808016A BR 9808016 A BR9808016 A BR 9808016A BR 9808016 A BR9808016 A BR 9808016A
Authority
BR
Brazil
Prior art keywords
compositions
prostaglandin
methods
ocular hypertension
reducing
Prior art date
Application number
BR9808016-4A
Other languages
English (en)
Inventor
Kenneth Warren Reed
Shau-Fong Yen
Mary Sou
Regina Flinn Peacock
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=38729083&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9808016(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Priority to BRPI9816218A priority Critical patent/BRPI9816218B1/pt
Publication of BR9808016A publication Critical patent/BR9808016A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

Patente de Invenção: <B>"COMPOSIçõES E MéTODOS PARA REDUçãO DA HIPERTENSãO OCULAR"<D>. Composição oftálmica aperfeiçoada, incluindo agentes ativos de prostaglandina, que é particularmente útil na redução da pressão intraocular associada a glaucoma. Aperfeiçoamentos na eficácia da redução da PIO, eficácia conservante e concentrações reduzidas de aditivos são conseguido utilizando-se as composições apresentadas, que incluem um agente ativo de prostaglandina (por exemplo, isopropil unoprostona, um metabólito de uma prostaglandina da série F,) juntamente com tensoativos não-iónicos, conservantes e agentes de ajuste de tonicidade não-iónicos selecionados.
BR9808016-4A 1997-03-17 1998-03-13 Composições e métodos para redução da hipertensão ocular BR9808016A (pt)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BRPI9816218A BRPI9816218B1 (pt) 1997-03-17 1998-03-13 "composições para redução da hipertensão ocular, e seu uso na preparação de composições oftálmicas"

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US81922197A 1997-03-17 1997-03-17
PCT/EP1998/001483 WO1998041208A1 (en) 1997-03-17 1998-03-13 Compositions and methods for reducing ocular hypertension

Publications (1)

Publication Number Publication Date
BR9808016A true BR9808016A (pt) 2000-03-08

Family

ID=38729083

Family Applications (2)

Application Number Title Priority Date Filing Date
BRPI9816218A BRPI9816218B1 (pt) 1997-03-17 1998-03-13 "composições para redução da hipertensão ocular, e seu uso na preparação de composições oftálmicas"
BR9808016-4A BR9808016A (pt) 1997-03-17 1998-03-13 Composições e métodos para redução da hipertensão ocular

Family Applications Before (1)

Application Number Title Priority Date Filing Date
BRPI9816218A BRPI9816218B1 (pt) 1997-03-17 1998-03-13 "composições para redução da hipertensão ocular, e seu uso na preparação de composições oftálmicas"

Country Status (33)

Country Link
EP (1) EP0969846B2 (pt)
JP (2) JP4920124B2 (pt)
KR (1) KR100555818B1 (pt)
CN (1) CN1236775C (pt)
AR (2) AR002194A1 (pt)
AT (1) ATE257385T1 (pt)
AU (1) AU738781B2 (pt)
BR (2) BRPI9816218B1 (pt)
CA (1) CA2280089C (pt)
CL (1) CL2009001870A1 (pt)
CO (1) CO4940427A1 (pt)
CY (1) CY2526B1 (pt)
CZ (1) CZ299833B6 (pt)
DE (1) DE69820997T3 (pt)
DK (1) DK0969846T4 (pt)
EE (1) EE04091B1 (pt)
ES (1) ES2214706T5 (pt)
HK (1) HK1026841A1 (pt)
HU (1) HU228896B1 (pt)
ID (1) ID22389A (pt)
IL (1) IL131041A0 (pt)
MY (1) MY122237A (pt)
NO (1) NO327713B1 (pt)
NZ (1) NZ337322A (pt)
PE (1) PE61899A1 (pt)
PL (1) PL197509B1 (pt)
PT (1) PT969846E (pt)
RU (1) RU2197970C2 (pt)
SI (1) SI0969846T2 (pt)
TW (1) TW527187B (pt)
UA (1) UA63938C2 (pt)
WO (1) WO1998041208A1 (pt)
ZA (1) ZA982188B (pt)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6011062A (en) * 1994-12-22 2000-01-04 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.
US6187818B1 (en) * 1998-06-17 2001-02-13 Pharmacia & Upjohn Company Prostaglandins formulation and process
JP4880808B2 (ja) * 1999-11-15 2012-02-22 久光製薬株式会社 人工涙液型点眼剤組成物
JP4000505B2 (ja) 1999-12-01 2007-10-31 第一三共株式会社 緑内障を治療するための併用剤
ES2357551T3 (es) * 2000-09-13 2011-04-27 Santen Pharmaceutical Co., Ltd. Colirio.
WO2002045748A1 (fr) * 2000-12-05 2002-06-13 Sankyo Company, Limited Compositions d'abaissement de la tension oculaire pour administration topique
US20020198209A1 (en) * 2001-05-03 2002-12-26 Allergan Sales Inc. Compositions having enhanced pharmacokinetic characteristics
US7074827B2 (en) * 2002-10-24 2006-07-11 Sucampo Ag (Usa) Inc. Method for treating ocular hypertension and glaucoma
CN1933833B (zh) * 2004-03-18 2011-09-07 株式会社·R-技术上野 含有噻唑衍生物的含水组合物
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
GB0501192D0 (en) * 2005-01-20 2005-03-02 Resolution Chemicals Ltd Stable prostaglandin-containing compositions
US7851504B2 (en) * 2005-03-16 2010-12-14 Allergan, Inc. Enhanced bimatoprost ophthalmic solution
US8030349B2 (en) * 2005-08-02 2011-10-04 Santen Pharmaceutical Co., Ltd. Method for prevention of degradation of thermally unstable medicament
JP5252787B2 (ja) * 2005-08-02 2013-07-31 参天製薬株式会社 熱的に不安定な薬物の分解抑制方法
JP2007099647A (ja) * 2005-09-30 2007-04-19 Kobayashi Pharmaceut Co Ltd 粘膜適用組成物
US8168206B1 (en) 2005-10-06 2012-05-01 Allergan, Inc. Animal protein-free pharmaceutical compositions
CN101400354B (zh) * 2006-03-13 2014-10-22 株式会社·R-技术上野 水性组合物
AR059927A1 (es) * 2006-03-17 2008-05-07 Johnson & Johnson Vision Care Metodos para la estabilizacion de composiciones inestables a la oxidacion y composiciones oftalmicas estabilizadas
RU2465898C2 (ru) * 2006-10-31 2012-11-10 Алькон Рисерч, Лтд. Модуляторы связывания pai-1 для лечения глазных болезней
US20100120908A1 (en) * 2007-02-07 2010-05-13 Teika Pharmaceutical Co., Ltd Eye drop preparation comprising latanoprost
JP2009073788A (ja) * 2007-09-21 2009-04-09 Teika Seiyaku Kk イソプロピルウノプロストン含有眼用組成物
NZ584275A (en) * 2007-10-08 2012-06-29 Fovea Pharmaceuticals Aqueous cyclosporine ophthalmic formulations
WO2009117242A2 (en) * 2008-03-17 2009-09-24 Alcon Research, Ltd. Aqueous pharmaceutical compositions containing borate-polyol complexes
TWI544927B (zh) * 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
EP2127638A1 (en) 2008-05-30 2009-12-02 Santen Pharmaceutical Co., Ltd Method and composition for treating ocular hypertension and glaucoma
US8952051B2 (en) * 2009-11-05 2015-02-10 Allergan, Inc. Ophthalmic formulations containing substituted gamma lactams and methods for use thereof
WO2012141334A1 (en) * 2011-04-12 2012-10-18 R-Tech Ueno, Ltd. Aqueous ophthalmic composition
US20130029919A1 (en) 2011-07-26 2013-01-31 Allergan, Inc. Two part formulation system for opthalmic delivery
EP2567689A1 (en) 2011-09-12 2013-03-13 Visiotact Pharma Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid
US8957048B2 (en) 2011-10-06 2015-02-17 Allergan, Inc. Compositions for the treatment of dry eye
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
PT2787969T (pt) 2011-12-07 2021-11-09 Allergan Inc Entrega eficiente de lípidos para o filme lacrimal humano utilizando um sistema de emulsão sensível ao sal
JP6768653B2 (ja) 2014-11-25 2020-10-14 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 安定したオメガ−３眼科用組成物
CN113164043B (zh) * 2018-09-21 2024-10-22 奥夫博医疗创新有限公司 用于青光眼的组合物和方法
MX2021012399A (es) 2019-04-12 2021-12-10 Ecolab Usa Inc Limpiador antimicrobiano multiuso y métodos de fabricación y uso de este.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0458587B1 (en) * 1990-05-22 1993-07-14 R-Tech Ueno Ltd. Synergistic combination for ophthalmic use
US5767154A (en) * 1991-02-07 1998-06-16 Allergan 5-trans-prostaglandins of the F series and their use as ocular hypotensives
WO1992013836A1 (en) * 1991-02-07 1992-08-20 Allergan, Inc. 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives
CN1129400A (zh) * 1994-05-06 1996-08-21 阿尔康实验室公司 维生素e生育酚衍生物在眼科组合物中的应用
US5631287A (en) † 1994-12-22 1997-05-20 Alcon Laboratories, Inc. Storage-stable prostaglandin compositions
US5558876A (en) * 1995-03-29 1996-09-24 Alcon Laboratories, Inc. Topical ophthalmic acidic drug formulations
AR002194A1 (es) * 1997-03-17 1998-01-07 Sanchez Reynaldo Alemany Instrumento computarizado para el analisis del movimiento.

Also Published As

Publication number Publication date
AU7035398A (en) 1998-10-12
CN1236775C (zh) 2006-01-18
ATE257385T1 (de) 2004-01-15
AR011192A1 (es) 2000-08-02
CO4940427A1 (es) 2000-07-24
SI0969846T1 (en) 2004-06-30
CN1249687A (zh) 2000-04-05
PT969846E (pt) 2004-05-31
HUP0002194A2 (hu) 2000-12-28
JP4920124B2 (ja) 2012-04-18
NO994481D0 (no) 1999-09-16
KR100555818B1 (ko) 2006-03-03
CL2009001870A1 (es) 2010-01-22
EP0969846B2 (en) 2010-08-25
WO1998041208A1 (en) 1998-09-24
DK0969846T4 (da) 2010-12-20
ES2214706T3 (es) 2004-09-16
CY2526B1 (en) 2006-02-08
BRPI9816218B1 (pt) 2016-04-12
RU2197970C2 (ru) 2003-02-10
JP2010043110A (ja) 2010-02-25
CA2280089A1 (en) 1998-09-24
DE69820997D1 (de) 2004-02-12
DE69820997T2 (de) 2004-12-09
AU738781B2 (en) 2001-09-27
EP0969846B1 (en) 2004-01-07
CZ325799A3 (cs) 2000-01-12
DK0969846T3 (da) 2004-04-13
PE61899A1 (es) 1999-06-30
AR002194A1 (es) 1998-01-07
PL197509B1 (pl) 2008-04-30
TW527187B (en) 2003-04-11
NO994481L (no) 1999-09-16
NZ337322A (en) 2001-05-25
ES2214706T5 (es) 2011-02-02
NO327713B1 (no) 2009-09-14
ID22389A (id) 1999-10-07
MY122237A (en) 2006-04-29
SI0969846T2 (sl) 2010-12-31
ZA982188B (en) 1998-09-17
IL131041A0 (en) 2001-01-28
JP2001515502A (ja) 2001-09-18
PL335168A1 (en) 2000-04-10
UA63938C2 (uk) 2004-02-16
HU228896B1 (en) 2013-06-28
HK1026841A1 (en) 2000-12-29
EE04091B1 (et) 2003-08-15
HUP0002194A3 (en) 2012-08-28
EE9900410A (et) 2000-04-17
CZ299833B6 (cs) 2008-12-10
DE69820997T3 (de) 2011-10-06
EP0969846A1 (en) 2000-01-12
CA2280089C (en) 2009-03-03
KR20000076330A (ko) 2000-12-26

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Legal Events

Date Code Title Description
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO DISPOSTO NOS ARTIGOS 8O, 11 E 25 DA LPI

B12B Appeal against refusal [chapter 12.2 patent gazette]
B15K Others concerning applications: alteration of classification

Free format text: ALTERADA DA INT.CL: A61K 31/557, A61K 9/00, AO1B 1/00

Ipc: A61K 31/557 (2010.01), A61K 9/00 (2010.01), A61P 2