PE61899A1 - Composicion farmaceutica para reducir la hipertension ocular que comprende una prostaglandina y un agente de ajuste de tonicidad no ionico - Google Patents
Composicion farmaceutica para reducir la hipertension ocular que comprende una prostaglandina y un agente de ajuste de tonicidad no ionicoInfo
- Publication number
- PE61899A1 PE61899A1 PE1998000177A PE00017798A PE61899A1 PE 61899 A1 PE61899 A1 PE 61899A1 PE 1998000177 A PE1998000177 A PE 1998000177A PE 00017798 A PE00017798 A PE 00017798A PE 61899 A1 PE61899 A1 PE 61899A1
- Authority
- PE
- Peru
- Prior art keywords
- composition
- mixtures
- conservative
- ionic
- prostaglandine
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
- A61K31/5575—Eicosanoids, e.g. leukotrienes or prostaglandins having a cyclopentane, e.g. prostaglandin E2, prostaglandin F2-alpha
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Ophthalmology & Optometry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
Abstract
SE REFIERE A UNA COMPOSICION OFTALMICA QUE COMPRENDE a)PROSTAGLANDINA , SUS METABOLITOS, DERIVADOS, SALES Y MEZCLAS; b) CONSERVADOR OFTALMICO, SELECCIONADO ENTRE SULFATO DE POLIMIXINA B, COMPUESTOS DE AMONIO CUATERNARIO; CONSERVADOR DEBIL COMO PEROXIDOS, GENERADORES DE PEROXIDOS Y SUS MEZCLAS; ENTRE OTROS c) UN AGENTE DE AJUSTE DE TONICIDAD NO IONICO PRESENTE EN UNA CONCENTRACION SUFICIENTE PARA i)AJUSTAR LA TONICIDAD DE LA COMPOSICION; ii)INCREMENTAR LA EFECTIVIDAD DEL CONSERVADOR, SELECCIONADO ENTRE MANITOL, SORBITOL, GLICEROL, ENTRE OTROS; d)UN VEHICULO OFTALMICAMENTE ACEPTABLE; COMPRENDE ADEMAS UN AGENTE DE QUELACION COMO EDTA O SU SAL; UN TENSOACTIVO NO IONICO SELECCIONADO DE ESTERES DE ACIDO GRASO DE SORBITAN DE POLIOXIETILENO, ETERES ALQUILICOS DE POLIOEXIETILENO, POLISORBATO 80 Y SUS MEZCLAS, ENTRE OTROS. EL AGENTE ACTIVO ES UN 13,14-DIHIDRO-15-CETO-20-ETIL-PROSTAGLANDINA F2O-ESTER ISOPROPILICO. TAMBIEN COMPRENDE UN REGULADOR DE pH COMO EDTA, BORATOS Y FOSFONATOS, QUE MANTIENE LA COMPOSICION EN UN pH DE 5,5 A 8,5 DURANTE UN ANO. UNA COMPOSICION PREFERIDA ES UN AGENTE ACTIVO DE PROSTAGLANDINA, UN PRIMER TENSOACTIVO NO IONICO COMO POLISORBATO Y UN SEGUNDO TENSOACTIVO NO IONICO COMO COMPUESTO BRIJ Y UN VEHICULO OFTALMICAMENTE ACEPTABLE. LA COMPOSICION PUEDE SER UTIL PARA LA HIPERTENSION OCULAR
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US81922197A | 1997-03-17 | 1997-03-17 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PE61899A1 true PE61899A1 (es) | 1999-06-30 |
Family
ID=38729083
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PE1998000177A PE61899A1 (es) | 1997-03-17 | 1998-03-13 | Composicion farmaceutica para reducir la hipertension ocular que comprende una prostaglandina y un agente de ajuste de tonicidad no ionico |
Country Status (33)
| Country | Link |
|---|---|
| EP (1) | EP0969846B2 (es) |
| JP (2) | JP4920124B2 (es) |
| KR (1) | KR100555818B1 (es) |
| CN (1) | CN1236775C (es) |
| AR (2) | AR002194A1 (es) |
| AT (1) | ATE257385T1 (es) |
| AU (1) | AU738781B2 (es) |
| BR (2) | BRPI9816218B1 (es) |
| CA (1) | CA2280089C (es) |
| CL (1) | CL2009001870A1 (es) |
| CO (1) | CO4940427A1 (es) |
| CY (1) | CY2526B1 (es) |
| CZ (1) | CZ299833B6 (es) |
| DE (1) | DE69820997T3 (es) |
| DK (1) | DK0969846T4 (es) |
| EE (1) | EE04091B1 (es) |
| ES (1) | ES2214706T5 (es) |
| HK (1) | HK1026841A1 (es) |
| HU (1) | HU228896B1 (es) |
| ID (1) | ID22389A (es) |
| IL (1) | IL131041A0 (es) |
| MY (1) | MY122237A (es) |
| NO (1) | NO327713B1 (es) |
| NZ (1) | NZ337322A (es) |
| PE (1) | PE61899A1 (es) |
| PL (1) | PL197509B1 (es) |
| PT (1) | PT969846E (es) |
| RU (1) | RU2197970C2 (es) |
| SI (1) | SI0969846T2 (es) |
| TW (1) | TW527187B (es) |
| UA (1) | UA63938C2 (es) |
| WO (1) | WO1998041208A1 (es) |
| ZA (1) | ZA982188B (es) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6011062A (en) * | 1994-12-22 | 2000-01-04 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
| AR002194A1 (es) * | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
| US6187818B1 (en) * | 1998-06-17 | 2001-02-13 | Pharmacia & Upjohn Company | Prostaglandins formulation and process |
| JP4880808B2 (ja) * | 1999-11-15 | 2012-02-22 | 久光製薬株式会社 | 人工涙液型点眼剤組成物 |
| JP4000505B2 (ja) | 1999-12-01 | 2007-10-31 | 第一三共株式会社 | 緑内障を治療するための併用剤 |
| ES2357551T3 (es) * | 2000-09-13 | 2011-04-27 | Santen Pharmaceutical Co., Ltd. | Colirio. |
| WO2002045748A1 (fr) * | 2000-12-05 | 2002-06-13 | Sankyo Company, Limited | Compositions d'abaissement de la tension oculaire pour administration topique |
| US20020198209A1 (en) * | 2001-05-03 | 2002-12-26 | Allergan Sales Inc. | Compositions having enhanced pharmacokinetic characteristics |
| US7074827B2 (en) * | 2002-10-24 | 2006-07-11 | Sucampo Ag (Usa) Inc. | Method for treating ocular hypertension and glaucoma |
| CN1933833B (zh) * | 2004-03-18 | 2011-09-07 | 株式会社·R-技术上野 | 含有噻唑衍生物的含水组合物 |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| GB0501192D0 (en) * | 2005-01-20 | 2005-03-02 | Resolution Chemicals Ltd | Stable prostaglandin-containing compositions |
| US7851504B2 (en) * | 2005-03-16 | 2010-12-14 | Allergan, Inc. | Enhanced bimatoprost ophthalmic solution |
| US8030349B2 (en) * | 2005-08-02 | 2011-10-04 | Santen Pharmaceutical Co., Ltd. | Method for prevention of degradation of thermally unstable medicament |
| JP5252787B2 (ja) * | 2005-08-02 | 2013-07-31 | 参天製薬株式会社 | 熱的に不安定な薬物の分解抑制方法 |
| JP2007099647A (ja) * | 2005-09-30 | 2007-04-19 | Kobayashi Pharmaceut Co Ltd | 粘膜適用組成物 |
| US8168206B1 (en) | 2005-10-06 | 2012-05-01 | Allergan, Inc. | Animal protein-free pharmaceutical compositions |
| CN101400354B (zh) * | 2006-03-13 | 2014-10-22 | 株式会社·R-技术上野 | 水性组合物 |
| AR059927A1 (es) * | 2006-03-17 | 2008-05-07 | Johnson & Johnson Vision Care | Metodos para la estabilizacion de composiciones inestables a la oxidacion y composiciones oftalmicas estabilizadas |
| RU2465898C2 (ru) * | 2006-10-31 | 2012-11-10 | Алькон Рисерч, Лтд. | Модуляторы связывания pai-1 для лечения глазных болезней |
| US20100120908A1 (en) * | 2007-02-07 | 2010-05-13 | Teika Pharmaceutical Co., Ltd | Eye drop preparation comprising latanoprost |
| JP2009073788A (ja) * | 2007-09-21 | 2009-04-09 | Teika Seiyaku Kk | イソプロピルウノプロストン含有眼用組成物 |
| NZ584275A (en) * | 2007-10-08 | 2012-06-29 | Fovea Pharmaceuticals | Aqueous cyclosporine ophthalmic formulations |
| WO2009117242A2 (en) * | 2008-03-17 | 2009-09-24 | Alcon Research, Ltd. | Aqueous pharmaceutical compositions containing borate-polyol complexes |
| TWI544927B (zh) * | 2008-03-17 | 2016-08-11 | 愛爾康研究有限公司 | 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物 |
| EP2127638A1 (en) | 2008-05-30 | 2009-12-02 | Santen Pharmaceutical Co., Ltd | Method and composition for treating ocular hypertension and glaucoma |
| US8952051B2 (en) * | 2009-11-05 | 2015-02-10 | Allergan, Inc. | Ophthalmic formulations containing substituted gamma lactams and methods for use thereof |
| WO2012141334A1 (en) * | 2011-04-12 | 2012-10-18 | R-Tech Ueno, Ltd. | Aqueous ophthalmic composition |
| US20130029919A1 (en) | 2011-07-26 | 2013-01-31 | Allergan, Inc. | Two part formulation system for opthalmic delivery |
| EP2567689A1 (en) | 2011-09-12 | 2013-03-13 | Visiotact Pharma | Ophthtalmic compositions comprising prostaglandin F2 alpha derivatives and hyaluronic acid |
| US8957048B2 (en) | 2011-10-06 | 2015-02-17 | Allergan, Inc. | Compositions for the treatment of dry eye |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| PT2787969T (pt) | 2011-12-07 | 2021-11-09 | Allergan Inc | Entrega eficiente de lípidos para o filme lacrimal humano utilizando um sistema de emulsão sensível ao sal |
| JP6768653B2 (ja) | 2014-11-25 | 2020-10-14 | アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ | 安定したオメガ−３眼科用組成物 |
| CN113164043B (zh) * | 2018-09-21 | 2024-10-22 | 奥夫博医疗创新有限公司 | 用于青光眼的组合物和方法 |
| MX2021012399A (es) | 2019-04-12 | 2021-12-10 | Ecolab Usa Inc | Limpiador antimicrobiano multiuso y métodos de fabricación y uso de este. |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0458587B1 (en) * | 1990-05-22 | 1993-07-14 | R-Tech Ueno Ltd. | Synergistic combination for ophthalmic use |
| US5767154A (en) * | 1991-02-07 | 1998-06-16 | Allergan | 5-trans-prostaglandins of the F series and their use as ocular hypotensives |
| WO1992013836A1 (en) * | 1991-02-07 | 1992-08-20 | Allergan, Inc. | 2-decarboxyl-2-hydroxyalkyl-5-trans prostaglandin f derivatives |
| CN1129400A (zh) * | 1994-05-06 | 1996-08-21 | 阿尔康实验室公司 | 维生素e生育酚衍生物在眼科组合物中的应用 |
| US5631287A (en) † | 1994-12-22 | 1997-05-20 | Alcon Laboratories, Inc. | Storage-stable prostaglandin compositions |
| US5558876A (en) * | 1995-03-29 | 1996-09-24 | Alcon Laboratories, Inc. | Topical ophthalmic acidic drug formulations |
| AR002194A1 (es) * | 1997-03-17 | 1998-01-07 | Sanchez Reynaldo Alemany | Instrumento computarizado para el analisis del movimiento. |
-
1996
- 1996-06-03 AR ARP960102868A patent/AR002194A1/es unknown
-
1998
- 1998-03-09 MY MYPI98001017A patent/MY122237A/en unknown
- 1998-03-13 RU RU99121641/14A patent/RU2197970C2/ru not_active IP Right Cessation
- 1998-03-13 IL IL13104198A patent/IL131041A0/xx not_active IP Right Cessation
- 1998-03-13 CZ CZ0325799A patent/CZ299833B6/cs not_active IP Right Cessation
- 1998-03-13 DK DK98916948.7T patent/DK0969846T4/da active
- 1998-03-13 KR KR1019997008431A patent/KR100555818B1/ko not_active IP Right Cessation
- 1998-03-13 DE DE69820997T patent/DE69820997T3/de not_active Expired - Lifetime
- 1998-03-13 ES ES98916948T patent/ES2214706T5/es not_active Expired - Lifetime
- 1998-03-13 EP EP98916948A patent/EP0969846B2/en not_active Expired - Lifetime
- 1998-03-13 EE EEP199900410A patent/EE04091B1/xx not_active IP Right Cessation
- 1998-03-13 CN CNB988030195A patent/CN1236775C/zh not_active Expired - Fee Related
- 1998-03-13 HU HU0002194A patent/HU228896B1/hu not_active IP Right Cessation
- 1998-03-13 NZ NZ337322A patent/NZ337322A/en not_active IP Right Cessation
- 1998-03-13 WO PCT/EP1998/001483 patent/WO1998041208A1/en active IP Right Grant
- 1998-03-13 PT PT98916948T patent/PT969846E/pt unknown
- 1998-03-13 ID IDW991029A patent/ID22389A/id unknown
- 1998-03-13 JP JP54012698A patent/JP4920124B2/ja not_active Expired - Lifetime
- 1998-03-13 PL PL335168A patent/PL197509B1/pl unknown
- 1998-03-13 AU AU70353/98A patent/AU738781B2/en not_active Ceased
- 1998-03-13 CO CO98014184A patent/CO4940427A1/es unknown
- 1998-03-13 AT AT98916948T patent/ATE257385T1/de active
- 1998-03-13 BR BRPI9816218A patent/BRPI9816218B1/pt not_active IP Right Cessation
- 1998-03-13 AR ARP980101150A patent/AR011192A1/es not_active Application Discontinuation
- 1998-03-13 SI SI9830616T patent/SI0969846T2/sl unknown
- 1998-03-13 PE PE1998000177A patent/PE61899A1/es not_active Application Discontinuation
- 1998-03-13 UA UA99095110A patent/UA63938C2/uk unknown
- 1998-03-13 CA CA002280089A patent/CA2280089C/en not_active Expired - Fee Related
- 1998-03-13 BR BR9808016-4A patent/BR9808016A/pt not_active Application Discontinuation
- 1998-03-16 ZA ZA982188A patent/ZA982188B/xx unknown
- 1998-03-16 TW TW087103809A patent/TW527187B/zh not_active IP Right Cessation
-
1999
- 1999-09-16 NO NO19994481A patent/NO327713B1/no not_active IP Right Cessation
-
2000
- 2000-07-11 HK HK00104263A patent/HK1026841A1/xx not_active IP Right Cessation
-
2005
- 2005-05-26 CY CY0500033A patent/CY2526B1/xx unknown
-
2009
- 2009-09-16 CL CL2009001870A patent/CL2009001870A1/es unknown
- 2009-10-09 JP JP2009235214A patent/JP2010043110A/ja active Pending
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Grant, registration | ||
| FD | Application declared void or lapsed |