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BR9708654A - Derivados de 3-[(1,2,3,4-tetrahidroisoquinolein-2-il)metil]-8-azabici clo [3.2.1]octano sua preparacão e sua aplicacão em terapia - Google Patents

Derivados de 3-[(1,2,3,4-tetrahidroisoquinolein-2-il)metil]-8-azabici clo [3.2.1]octano sua preparacão e sua aplicacão em terapia

Info

Publication number
BR9708654A
BR9708654A BR9708654A BR9708654A BR9708654A BR 9708654 A BR9708654 A BR 9708654A BR 9708654 A BR9708654 A BR 9708654A BR 9708654 A BR9708654 A BR 9708654A BR 9708654 A BR9708654 A BR 9708654A
Authority
BR
Brazil
Prior art keywords
tetrahydroisoquinolein
azabici
clo
octane
therapy
Prior art date
Application number
BR9708654A
Other languages
English (en)
Inventor
Mireille Sevrin
Benoit Marabout
Pascal George
Jean-Pierre Merly
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of BR9708654A publication Critical patent/BR9708654A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BR9708654A 1996-04-12 1997-04-10 Derivados de 3-[(1,2,3,4-tetrahidroisoquinolein-2-il)metil]-8-azabici clo [3.2.1]octano sua preparacão e sua aplicacão em terapia BR9708654A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9604565A FR2747386B1 (fr) 1996-04-12 1996-04-12 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
PCT/FR1997/000634 WO1997038998A1 (fr) 1996-04-12 1997-04-10 Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
BR9708654A true BR9708654A (pt) 1999-08-03

Family

ID=9491132

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9708654A BR9708654A (pt) 1996-04-12 1997-04-10 Derivados de 3-[(1,2,3,4-tetrahidroisoquinolein-2-il)metil]-8-azabici clo [3.2.1]octano sua preparacão e sua aplicacão em terapia

Country Status (22)

Country Link
EP (1) EP0892800A1 (pt)
JP (1) JP2000512620A (pt)
KR (1) KR20000005392A (pt)
CN (1) CN1216046A (pt)
AR (1) AR008587A1 (pt)
AU (1) AU2640997A (pt)
BG (1) BG102779A (pt)
BR (1) BR9708654A (pt)
CA (1) CA2251335A1 (pt)
CO (1) CO4900067A1 (pt)
CZ (1) CZ326898A3 (pt)
EE (1) EE9800396A (pt)
FR (1) FR2747386B1 (pt)
IL (1) IL126473A0 (pt)
NO (1) NO984736L (pt)
NZ (1) NZ332257A (pt)
PL (1) PL329243A1 (pt)
SK (1) SK141598A3 (pt)
TR (1) TR199801839T2 (pt)
TW (1) TW407158B (pt)
WO (1) WO1997038998A1 (pt)
ZA (1) ZA973124B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2303851A1 (en) * 2008-06-27 2011-04-06 H. Lundbeck A/S Novel phenolic and catecholic amines and prodrugs thereof
US10870660B2 (en) 2016-07-28 2020-12-22 Shionogi & Co., Ltd. Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect
JPWO2019146739A1 (ja) 2018-01-26 2021-01-07 塩野義製薬株式会社 ドーパミンｄ３受容体拮抗作用を有する縮環化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8701682A (nl) * 1986-07-30 1988-02-16 Sandoz Ag Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
EP0306375A1 (fr) * 1987-08-07 1989-03-08 Synthelabo Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) * 1988-07-12 1993-05-13 Synthelabo Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) * 1990-04-24 1993-03-12 Synthelabo Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

Also Published As

Publication number Publication date
NO984736D0 (no) 1998-10-09
CZ326898A3 (cs) 1999-01-13
EE9800396A (et) 1999-06-15
SK141598A3 (en) 1999-03-12
KR20000005392A (ko) 2000-01-25
ZA973124B (en) 1997-11-05
FR2747386B1 (fr) 1998-05-15
CA2251335A1 (en) 1997-10-23
AR008587A1 (es) 2000-02-09
JP2000512620A (ja) 2000-09-26
IL126473A0 (en) 1999-08-17
WO1997038998A1 (fr) 1997-10-23
NZ332257A (en) 1999-03-29
TR199801839T2 (pt) 1998-12-21
PL329243A1 (en) 1999-03-15
TW407158B (en) 2000-10-01
FR2747386A1 (fr) 1997-10-17
CN1216046A (zh) 1999-05-05
NO984736L (no) 1998-11-23
CO4900067A1 (es) 2000-03-27
AU2640997A (en) 1997-11-07
EP0892800A1 (fr) 1999-01-27
BG102779A (en) 1999-09-30

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]