AU2640997A - 3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics - Google Patents

3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics

Info

Publication number: AU2640997A
Authority: AU; Australia
Prior art keywords: tetrahydroisoquinoline; azabicyclo; therapeutics; methyl; preparation
Prior art date: 1996-04-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Abandoned

Application number

AU26409/97A

Other languages

English (en)

Inventor

Pascal George

Benoit Marabout

Jean-Pierre Merly

Mireille Sevrin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Synthelabo SA

Original Assignee

Synthelabo SA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-12

Filing date

1997-04-10

Publication date

1997-11-07

1997-04-10 Application filed by Synthelabo SA filed Critical Synthelabo SA

1997-11-07 Publication of AU2640997A publication Critical patent/AU2640997A/en

Status Abandoned legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

AU26409/97A 1996-04-12 1997-04-10 3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics Abandoned AU2640997A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
FR9604565A FR2747386B1 (fr)	1996-04-12	1996-04-12	Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl] -8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique
FR9604565		1996-04-12
PCT/FR1997/000634 WO1997038998A1 (fr)	1996-04-12	1997-04-10	Derives de 3-[(1,2,3,4-tetrahydroisoquinolein-2-yl)methyl]-8-azabicyclo [3.2.1] octane, leur preparation et leur application en therapeutique

Publications (1)

Publication Number	Publication Date
AU2640997A true AU2640997A (en)	1997-11-07

Family

ID=9491132

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU26409/97A Abandoned AU2640997A (en)	1996-04-12	1997-04-10	3-{(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl}-8-azabicyclo {3.2.1}octane derivatives, their preparation and their application in therapeutics

Country Status (22)

Country	Link
EP (1)	EP0892800A1 (pt)
JP (1)	JP2000512620A (pt)
KR (1)	KR20000005392A (pt)
CN (1)	CN1216046A (pt)
AR (1)	AR008587A1 (pt)
AU (1)	AU2640997A (pt)
BG (1)	BG102779A (pt)
BR (1)	BR9708654A (pt)
CA (1)	CA2251335A1 (pt)
CO (1)	CO4900067A1 (pt)
CZ (1)	CZ326898A3 (pt)
EE (1)	EE9800396A (pt)
FR (1)	FR2747386B1 (pt)
IL (1)	IL126473A0 (pt)
NO (1)	NO984736L (pt)
NZ (1)	NZ332257A (pt)
PL (1)	PL329243A1 (pt)
SK (1)	SK141598A3 (pt)
TR (1)	TR199801839T2 (pt)
TW (1)	TW407158B (pt)
WO (1)	WO1997038998A1 (pt)
ZA (1)	ZA973124B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2303851A1 (en) *	2008-06-27	2011-04-06	H. Lundbeck A/S	Novel phenolic and catecholic amines and prodrugs thereof
US10870660B2 (en)	2016-07-28	2020-12-22	Shionogi & Co., Ltd.	Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect
JPWO2019146739A1 (ja)	2018-01-26	2021-01-07	塩野義製薬株式会社	ドーパミンｄ３受容体拮抗作用を有する縮環化合物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8701682A (nl) *	1986-07-30	1988-02-16	Sandoz Ag	Werkwijze voor het therapeutisch toepassen van serotonine antagonisten, aktieve verbindingen en farmaceutische preparaten die deze verbindingen bevatten.
EP0306375A1 (fr) *	1987-08-07	1989-03-08	Synthelabo	Dérivés de[(pipéridinyl-4)méthyl]-2 tétrahydro-1,2,3,4 isoquinoléine, leur préparation et leur application en thérapeutique
IL89156A (en) *	1988-07-12	1993-05-13	Synthelabo	Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (fr) *	1990-04-24	1993-03-12	Synthelabo	Derives de [(tetrahydro-1,2,3,4 isoquinoleinyl-2)methyl]-4 piperidinecarboxylates-1 d'alkyle, leur preparation et leur application en therapeutique.

1996
- 1996-04-12 FR FR9604565A patent/FR2747386B1/fr not_active Expired - Fee Related
1997
- 1997-04-10 AR ARP970101421A patent/AR008587A1/es unknown
- 1997-04-10 EE EE9800396A patent/EE9800396A/xx unknown
- 1997-04-10 PL PL97329243A patent/PL329243A1/xx unknown
- 1997-04-10 NZ NZ332257A patent/NZ332257A/xx unknown
- 1997-04-10 TW TW086104625A patent/TW407158B/zh active
- 1997-04-10 JP JP09536794A patent/JP2000512620A/ja active Pending
- 1997-04-10 TR TR1998/01839T patent/TR199801839T2/xx unknown
- 1997-04-10 CZ CZ983268A patent/CZ326898A3/cs unknown
- 1997-04-10 IL IL12647397A patent/IL126473A0/xx unknown
- 1997-04-10 KR KR1019980708123A patent/KR20000005392A/ko not_active Application Discontinuation
- 1997-04-10 CA CA002251335A patent/CA2251335A1/en not_active Abandoned
- 1997-04-10 WO PCT/FR1997/000634 patent/WO1997038998A1/fr not_active Application Discontinuation
- 1997-04-10 AU AU26409/97A patent/AU2640997A/en not_active Abandoned
- 1997-04-10 BR BR9708654A patent/BR9708654A/pt not_active Application Discontinuation
- 1997-04-10 EP EP97918195A patent/EP0892800A1/fr not_active Withdrawn
- 1997-04-10 CN CN97193750A patent/CN1216046A/zh active Pending
- 1997-04-10 SK SK1415-98A patent/SK141598A3/sk unknown
- 1997-04-11 ZA ZA9703124A patent/ZA973124B/xx unknown
- 1997-04-11 CO CO97018806A patent/CO4900067A1/es unknown
1998
- 1998-09-18 BG BG102779A patent/BG102779A/xx unknown
- 1998-10-09 NO NO984736A patent/NO984736L/no not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO984736D0 (no)	1998-10-09
CZ326898A3 (cs)	1999-01-13
EE9800396A (et)	1999-06-15
SK141598A3 (en)	1999-03-12
KR20000005392A (ko)	2000-01-25
ZA973124B (en)	1997-11-05
FR2747386B1 (fr)	1998-05-15
CA2251335A1 (en)	1997-10-23
AR008587A1 (es)	2000-02-09
JP2000512620A (ja)	2000-09-26
IL126473A0 (en)	1999-08-17
WO1997038998A1 (fr)	1997-10-23
NZ332257A (en)	1999-03-29
TR199801839T2 (pt)	1998-12-21
PL329243A1 (en)	1999-03-15
TW407158B (en)	2000-10-01
FR2747386A1 (fr)	1997-10-17
CN1216046A (zh)	1999-05-05
NO984736L (no)	1998-11-23
CO4900067A1 (es)	2000-03-27
EP0892800A1 (fr)	1999-01-27
BG102779A (en)	1999-09-30
BR9708654A (pt)	1999-08-03

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Legal Events

Date	Code	Title	Description
2001-03-22	MK5	Application lapsed section 142(2)(e) - patent request and compl. specification not accepted