BR9708654A - Derivatives of 3 - [(1,2,3,4-tetrahydroisoquinolein-2-yl) methyl] -8-azabici clo [3.2.1] octane its preparation and its application in therapy - Google Patents

Derivatives of 3 - [(1,2,3,4-tetrahydroisoquinolein-2-yl) methyl] -8-azabici clo [3.2.1] octane its preparation and its application in therapy

Info

Publication number: BR9708654A
Authority: BR; Brazil
Prior art keywords: tetrahydroisoquinolein; azabici; clo; octane; therapy
Prior art date: 1996-04-12

Application number

BR9708654A

Other languages

Portuguese (pt)

Inventor

Mireille Sevrin

Benoit Marabout

Pascal George

Jean-Pierre Merly

Original Assignee

Synthelabo

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-04-12

Filing date

1997-04-10

Publication date

1999-08-03

1997-04-10 Application filed by Synthelabo filed Critical Synthelabo

1999-08-03 Publication of BR9708654A publication Critical patent/BR9708654A/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

BR9708654A 1996-04-12 1997-04-10 Derivatives of 3 - [(1,2,3,4-tetrahydroisoquinolein-2-yl) methyl] -8-azabici clo [3.2.1] octane its preparation and its application in therapy BR9708654A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9604565A FR2747386B1 (en)	1996-04-12	1996-04-12	DERIVATIVES OF 3 - [(1,2,3,4-TETRAHYDROISOQUINOLEIN-2-YL) METHYL] -8-AZABICYCLO [3.2.1] OCTANE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
PCT/FR1997/000634 WO1997038998A1 (en)	1996-04-12	1997-04-10	3-[(1,2,3,4-tetrahydroisoquinoline-2-yl)methyl]-8-azabicyclo[3.2.1]octane derivatives, their preparation and their application in therapeutics

Publications (1)

Publication Number	Publication Date
BR9708654A true BR9708654A (en)	1999-08-03

Family

ID=9491132

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BR9708654A BR9708654A (en)	1996-04-12	1997-04-10	Derivatives of 3 - [(1,2,3,4-tetrahydroisoquinolein-2-yl) methyl] -8-azabici clo [3.2.1] octane its preparation and its application in therapy

Country Status (22)

Country	Link
EP (1)	EP0892800A1 (en)
JP (1)	JP2000512620A (en)
KR (1)	KR20000005392A (en)
CN (1)	CN1216046A (en)
AR (1)	AR008587A1 (en)
AU (1)	AU2640997A (en)
BG (1)	BG102779A (en)
BR (1)	BR9708654A (en)
CA (1)	CA2251335A1 (en)
CO (1)	CO4900067A1 (en)
CZ (1)	CZ326898A3 (en)
EE (1)	EE9800396A (en)
FR (1)	FR2747386B1 (en)
IL (1)	IL126473A0 (en)
NO (1)	NO984736L (en)
NZ (1)	NZ332257A (en)
PL (1)	PL329243A1 (en)
SK (1)	SK141598A3 (en)
TR (1)	TR199801839T2 (en)
TW (1)	TW407158B (en)
WO (1)	WO1997038998A1 (en)
ZA (1)	ZA973124B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP2303851A1 (en) *	2008-06-27	2011-04-06	H. Lundbeck A/S	Novel phenolic and catecholic amines and prodrugs thereof
US10870660B2 (en)	2016-07-28	2020-12-22	Shionogi & Co., Ltd.	Nitrogen-containing condensed ring compounds having dopamine D3 antagonistic effect
JPWO2019146739A1 (en)	2018-01-26	2021-01-07	塩野義製薬株式会社	Fused ring compound with dopamine D3 receptor antagonistic activity

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL8701682A (en) *	1986-07-30	1988-02-16	Sandoz Ag	METHOD FOR THE THERAPEUTIC USE OF SEROTONIN ANTAGONISTS, ACTIVE COMPOUNDS AND PHARMACEUTICAL PREPARATIONS CONTAINING THESE COMPOUNDS
EP0306375A1 (en) *	1987-08-07	1989-03-08	Synthelabo	2-[(4-Piperidinyl)methyl]-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their use in therapy
IL89156A (en) *	1988-07-12	1993-05-13	Synthelabo	Derivatives of 2-((4-piperidinyl) methyl)- 1,2,3,4- tetrahydroisoquinoline, their preparation and their application in therapeutics
FR2661178B1 (en) *	1990-04-24	1993-03-12	Synthelabo	DERIVATIVES OF [(TETRAHYDRO-1,2,3,4 ISOQUINOLEINYL-2) METHYL] -4 PIPERIDINECARBOXYLATES-1 OF ALKYL, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION.

1996
- 1996-04-12 FR FR9604565A patent/FR2747386B1/en not_active Expired - Fee Related
1997
- 1997-04-10 AR ARP970101421A patent/AR008587A1/en unknown
- 1997-04-10 EE EE9800396A patent/EE9800396A/en unknown
- 1997-04-10 PL PL97329243A patent/PL329243A1/en unknown
- 1997-04-10 NZ NZ332257A patent/NZ332257A/en unknown
- 1997-04-10 TW TW086104625A patent/TW407158B/en active
- 1997-04-10 JP JP09536794A patent/JP2000512620A/en active Pending
- 1997-04-10 TR TR1998/01839T patent/TR199801839T2/xx unknown
- 1997-04-10 CZ CZ983268A patent/CZ326898A3/en unknown
- 1997-04-10 IL IL12647397A patent/IL126473A0/en unknown
- 1997-04-10 KR KR1019980708123A patent/KR20000005392A/en not_active Application Discontinuation
- 1997-04-10 CA CA002251335A patent/CA2251335A1/en not_active Abandoned
- 1997-04-10 WO PCT/FR1997/000634 patent/WO1997038998A1/en not_active Application Discontinuation
- 1997-04-10 AU AU26409/97A patent/AU2640997A/en not_active Abandoned
- 1997-04-10 BR BR9708654A patent/BR9708654A/en not_active Application Discontinuation
- 1997-04-10 EP EP97918195A patent/EP0892800A1/en not_active Withdrawn
- 1997-04-10 CN CN97193750A patent/CN1216046A/en active Pending
- 1997-04-10 SK SK1415-98A patent/SK141598A3/en unknown
- 1997-04-11 ZA ZA9703124A patent/ZA973124B/en unknown
- 1997-04-11 CO CO97018806A patent/CO4900067A1/en unknown
1998
- 1998-09-18 BG BG102779A patent/BG102779A/en unknown
- 1998-10-09 NO NO984736A patent/NO984736L/en not_active Application Discontinuation

Also Published As

Publication number	Publication date
NO984736D0 (en)	1998-10-09
CZ326898A3 (en)	1999-01-13
EE9800396A (en)	1999-06-15
SK141598A3 (en)	1999-03-12
KR20000005392A (en)	2000-01-25
ZA973124B (en)	1997-11-05
FR2747386B1 (en)	1998-05-15
CA2251335A1 (en)	1997-10-23
AR008587A1 (en)	2000-02-09
JP2000512620A (en)	2000-09-26
IL126473A0 (en)	1999-08-17
WO1997038998A1 (en)	1997-10-23
NZ332257A (en)	1999-03-29
TR199801839T2 (en)	1998-12-21
PL329243A1 (en)	1999-03-15
TW407158B (en)	2000-10-01
FR2747386A1 (en)	1997-10-17
CN1216046A (en)	1999-05-05
NO984736L (en)	1998-11-23
CO4900067A1 (en)	2000-03-27
AU2640997A (en)	1997-11-07
EP0892800A1 (en)	1999-01-27
BG102779A (en)	1999-09-30

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Legal Events

Date	Code	Title	Description
2003-10-21	FA10	Dismissal: dismissal - article 33 of industrial property law
2004-06-08	B11Y	Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]