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BR9612752A - Neutrocina - Google Patents

Neutrocina

Info

Publication number
BR9612752A
BR9612752A BR9612752-0A BR9612752A BR9612752A BR 9612752 A BR9612752 A BR 9612752A BR 9612752 A BR9612752 A BR 9612752A BR 9612752 A BR9612752 A BR 9612752A
Authority
BR
Brazil
Prior art keywords
neutrokine alpha
methods
immune system
related disorders
protein
Prior art date
Application number
BR9612752-0A
Other languages
English (en)
Inventor
Guo-Liang Yu
Reinhard Ebner
Jian Ni
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22256104&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9612752(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of BR9612752A publication Critical patent/BR9612752A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Wood Science & Technology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Pain & Pain Management (AREA)
  • Physics & Mathematics (AREA)
  • Transplantation (AREA)
  • Rheumatology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

"NEUTROCINA <244>". A presente invenção refere-se a uma nova proteína de Neutrocina <244>, a qual é um membro da família da proteína de TNF. Em particular, as moléculas de ácidos nucleicos isoladas são proporcionadas, codificando a proteína de Neutrocina <244> humana, incluindo as formas solúveis do domínio extracelular. Os polipetídeos de Neutrocina <244> são também proporcionados, como são os vetores, as células hospedeiras e os métodos recombinantes para a produção dos memos. A invenção adicionalmente refere-se aos métodos de exame para identificar os agonistas e os antagonistas de atividade de Neutrocina <244>. Também proporcionados são os métodos diagnósticos para a detecção de distúrbios relacionados ao sistema imune, e os métodos terapêuticos para o tratamento de distúrbios relacionados ao sistema imune.
BR9612752-0A 1996-10-25 1996-10-25 Neutrocina BR9612752A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1996/017957 WO1998018921A1 (en) 1996-10-25 1996-10-25 NEUTROKINE $g(a)

Publications (1)

Publication Number Publication Date
BR9612752A true BR9612752A (pt) 2000-01-18

Family

ID=22256104

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9612752-0A BR9612752A (pt) 1996-10-25 1996-10-25 Neutrocina

Country Status (14)

Country Link
EP (3) EP2230307A1 (pt)
JP (1) JP2001503263A (pt)
KR (2) KR20000052796A (pt)
CN (1) CN1539970A (pt)
AT (1) ATE302272T1 (pt)
AU (1) AU731553B2 (pt)
BR (1) BR9612752A (pt)
CA (2) CA2665133A1 (pt)
DE (1) DE69635088T3 (pt)
DK (1) DK0939804T4 (pt)
ES (1) ES2248823T5 (pt)
NZ (1) NZ334309A (pt)
PT (1) PT939804E (pt)
WO (1) WO1998018921A1 (pt)

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DE69635088T3 (de) 2012-01-26
ES2248823T5 (es) 2011-11-03
EP0939804B2 (en) 2011-06-15
ES2248823T3 (es) 2006-03-16
CN1539970A (zh) 2004-10-27
KR20000052796A (ko) 2000-08-25
AU731553B2 (en) 2001-04-05
EP1577391A1 (en) 2005-09-21
CA2266439C (en) 2009-06-16
EP2230307A1 (en) 2010-09-22
WO1998018921A1 (en) 1998-05-07
EP0939804A1 (en) 1999-09-08
AU7674596A (en) 1998-05-22
DK0939804T4 (da) 2011-07-18
NZ334309A (en) 2000-08-25
CA2665133A1 (en) 1998-05-07
EP0939804B1 (en) 2005-08-17
ATE302272T1 (de) 2005-09-15
CA2266439A1 (en) 1998-05-07
DE69635088D1 (de) 2005-09-22
KR20050004269A (ko) 2005-01-12
PT939804E (pt) 2005-11-30
DK0939804T3 (da) 2005-12-19
DE69635088T2 (de) 2006-06-14
JP2001503263A (ja) 2001-03-13

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