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BR9610347A - Bioconjugados de complexos de manganés de ligantes macrocíclicos contendo nitrogénio efetivos como catalisadores para a dismutação de superóxido - Google Patents

Bioconjugados de complexos de manganés de ligantes macrocíclicos contendo nitrogénio efetivos como catalisadores para a dismutação de superóxido

Info

Publication number
BR9610347A
BR9610347A BR9610347A BR9610347A BR9610347A BR 9610347 A BR9610347 A BR 9610347A BR 9610347 A BR9610347 A BR 9610347A BR 9610347 A BR9610347 A BR 9610347A BR 9610347 A BR9610347 A BR 9610347A
Authority
BR
Brazil
Prior art keywords
bioconjugates
catalysts
nitrogen
manganese complexes
containing macrocyclic
Prior art date
Application number
BR9610347A
Other languages
English (en)
Portuguese (pt)
Inventor
William L Neumann
Dennis P Riley
Randy H Weiss
Susan L Henke
Patrick J Lennon
Karl W Aston
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of BR9610347A publication Critical patent/BR9610347A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D259/00—Heterocyclic compounds containing rings having more than four nitrogen atoms as the only ring hetero atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicinal Preparation (AREA)
BR9610347A 1995-08-17 1996-08-14 Bioconjugados de complexos de manganés de ligantes macrocíclicos contendo nitrogénio efetivos como catalisadores para a dismutação de superóxido BR9610347A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US242195P 1995-08-17 1995-08-17
PCT/US1996/012767 WO1997006824A2 (en) 1995-08-17 1996-08-14 Bioconjugates of manganese complexes and their application as catalysts

Publications (1)

Publication Number Publication Date
BR9610347A true BR9610347A (pt) 1999-06-01

Family

ID=21700675

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610347A BR9610347A (pt) 1995-08-17 1996-08-14 Bioconjugados de complexos de manganés de ligantes macrocíclicos contendo nitrogénio efetivos como catalisadores para a dismutação de superóxido

Country Status (12)

Country Link
EP (1) EP0844886A2 (zh)
JP (1) JP2000513322A (zh)
KR (1) KR19990037647A (zh)
CN (1) CN1200039A (zh)
AU (1) AU700958B2 (zh)
BR (1) BR9610347A (zh)
CA (1) CA2229799A1 (zh)
CZ (1) CZ39898A3 (zh)
IL (1) IL123040A0 (zh)
NO (1) NO980649L (zh)
PL (1) PL324993A1 (zh)
WO (1) WO1997006824A2 (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL144503A0 (en) 1999-01-25 2002-05-23 Nat Jewish Med & Res Center Substituted porphyrins
CA2394959A1 (en) 1999-12-23 2001-07-05 Amersham Plc Labelled ascorbic acid derivatives
US20050176790A1 (en) 2001-02-28 2005-08-11 Johannes Bartholomaus Pharmaceutical salts
EP1439842A4 (en) 2001-06-01 2009-09-02 Nat Jewish Med & Res Center OXIDANT CAPTAIN FOR THE TREATMENT OF DIABETES OR FOR THE USE IN THE TRANSPLANTATION OR INDUCTION OF IMMUNOTOLERANE
CN102088991A (zh) 2008-05-13 2011-06-08 堪萨斯大学 金属提取肽标签和相关方法
ES2464728T3 (es) 2008-05-23 2014-06-03 National Jewish Health Compuestos para su uso en el tratamiento de lesiones asociadas con la exposición a una especie química alquilante
CA2849456C (en) * 2011-09-26 2021-12-07 Galera Therapeutics, Llc Methods for treatment of diseases
WO2013181461A2 (en) 2012-06-01 2013-12-05 University Of Kansas Metal abstraction peptide with superoxide dismutase activity
CN110520107A (zh) * 2017-02-15 2019-11-29 加莱拉实验室有限责任公司 用于局部肠递送的五氮杂大环状环配合物
CN108752383B (zh) * 2018-05-02 2020-10-30 江苏理工学院 一种具有sod活性的吡唑羧酸酯锰配合物及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4880832A (en) * 1987-03-06 1989-11-14 Sumitomo Pharmaceuticals Company, Ltd. Liposoluble platinum (II) complex and preparation thereof
DE69224839T2 (de) * 1991-07-19 1998-10-08 Monsanto Co Mangan-Komplexe mit Stickstoff enthaltenden makrozyklischen Liganden, wirksam als Superoxiddismutasekatalysatoren.
US6204259B1 (en) * 1993-01-14 2001-03-20 Monsanto Company Manganese complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
WO1995028968A1 (en) * 1994-04-22 1995-11-02 Monsanto Company Diagnostic image analysis with metal complexes
US6525041B1 (en) * 1995-06-06 2003-02-25 Pharmacia Corporation Manganese or iron complexes of nitrogen-containing macrocyclic ligands effective as catalysts for dismutating superoxide
EP0830351A1 (en) * 1995-06-07 1998-03-25 Monsanto Company Process for preparing substituted polyazamacrocycles

Also Published As

Publication number Publication date
CN1200039A (zh) 1998-11-25
EP0844886A2 (en) 1998-06-03
KR19990037647A (ko) 1999-05-25
WO1997006824A3 (en) 1997-07-03
NO980649L (no) 1998-04-02
JP2000513322A (ja) 2000-10-10
PL324993A1 (en) 1998-07-06
NO980649D0 (no) 1998-02-16
MX9801322A (es) 1998-05-31
CA2229799A1 (en) 1997-02-27
AU6765596A (en) 1997-03-12
CZ39898A3 (cs) 1998-07-15
AU700958B2 (en) 1999-01-14
WO1997006824A2 (en) 1997-02-27
IL123040A0 (en) 1998-09-24

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Legal Events

Date Code Title Description
FA10 Dismissal: dismissal - article 33 of industrial property law
B15K Others concerning applications: alteration of classification

Ipc: C07F 13/00 (2006.01), A61K 49/06 (2006.0