[go: up one dir, main page]

BR9504456A - Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao - Google Patents

Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao

Info

Publication number
BR9504456A
BR9504456A BR9504456A BR9504456A BR9504456A BR 9504456 A BR9504456 A BR 9504456A BR 9504456 A BR9504456 A BR 9504456A BR 9504456 A BR9504456 A BR 9504456A BR 9504456 A BR9504456 A BR 9504456A
Authority
BR
Brazil
Prior art keywords
preparation
medicine
compounds
alkoxy
formula
Prior art date
Application number
BR9504456A
Other languages
English (en)
Inventor
Manfred Dr Roesner
Uta-Maria Billhardt-Troughton
Reinhard Dr Kirsch
Joerg-Peter Dr Kleim
Christoph Dr Meichsner
Guenther Dr Ries
Irvin Dr Winkler
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of BR9504456A publication Critical patent/BR9504456A/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Dental Preparations (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Compounds Of Unknown Constitution (AREA)
BR9504456A 1994-10-19 1995-10-19 Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao BR9504456A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4437406A DE4437406A1 (de) 1994-10-19 1994-10-19 Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung

Publications (1)

Publication Number Publication Date
BR9504456A true BR9504456A (pt) 1997-05-20

Family

ID=6531202

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9504456A BR9504456A (pt) 1994-10-19 1995-10-19 Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao

Country Status (28)

Country Link
US (1) US5723461A (pt)
EP (1) EP0708093B1 (pt)
JP (1) JPH08225544A (pt)
KR (1) KR960014108A (pt)
CN (1) CN1094930C (pt)
AT (1) ATE198747T1 (pt)
AU (1) AU708293B2 (pt)
BR (1) BR9504456A (pt)
CA (1) CA2160859A1 (pt)
CZ (1) CZ271295A3 (pt)
DE (2) DE4437406A1 (pt)
DK (1) DK0708093T3 (pt)
ES (1) ES2154311T3 (pt)
FI (1) FI954946L (pt)
GR (1) GR3035673T3 (pt)
HK (1) HK1011988A1 (pt)
HR (1) HRP950524B1 (pt)
HU (1) HUT73485A (pt)
IL (1) IL115641A0 (pt)
MY (1) MY132057A (pt)
NO (1) NO306615B1 (pt)
NZ (1) NZ280258A (pt)
PL (1) PL184860B1 (pt)
PT (1) PT708093E (pt)
SI (1) SI9500329A (pt)
SK (1) SK128495A3 (pt)
TW (1) TW328954B (pt)
ZA (1) ZA958783B (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6369057B1 (en) * 1991-04-15 2002-04-09 Aventis Pharma Deutschland Gmbh Quinoxalines, processes for their preparation and their use
US6015800A (en) * 1997-09-03 2000-01-18 Warner-Lambert Company Substituted quinoxaline-2-ones as glutamate receptor antagonists
WO1999025327A2 (en) * 1997-11-14 1999-05-27 Warner-Lambert Company Small molecule intervention in hiv-1 replication
GB9901795D0 (en) * 1999-01-28 1999-03-17 Glaxo Group Ltd Chemical compounds
GB9911887D0 (en) * 1999-05-21 1999-07-21 Glaxo Group Ltd Methods and medicaments for post exposure prophylaxis of an hiv infection
WO2002087500A2 (en) * 2001-04-27 2002-11-07 Newbiotics, Inc. Viral enzyme activated prototoxophores and use of same to treat viral infections
WO2005018531A2 (fr) * 2003-08-26 2005-03-03 'chemical Diversity Research Institute', Ltd. Compositions pharmaceutiques, composes azo-heterocycliques et procedes de fabrication et d'utilisation correspondants
US7351709B2 (en) * 2004-06-09 2008-04-01 Wyeth Estrogen receptor ligands
BR112014026703B1 (pt) 2012-04-24 2022-10-25 Vertex Pharmaceuticals Incorporated Inibidores de dna-pk e seus usos, composição farmacêutica e seus usos, e método de sensibilização de uma célula
HRP20211855T1 (hr) 2013-03-12 2022-03-04 Vertex Pharmaceuticals Incorporated Inhibitori dnk-pk
LT3424920T (lt) 2013-10-17 2020-08-10 Vertex Pharmaceuticals Incorporated (s)-n-metil-8-(1-((2`-metil-[4,5`-bipirimidin]-6-il)amino)propan-2-il)chinolin-4-karboksamido ir jo deuterintų darinių, kaip dnr-pk inhibitorių, bendri kristalai
KR20190062485A (ko) 2016-09-27 2019-06-05 버텍스 파마슈티칼스 인코포레이티드 Dna-손상제 및 dna-pk 저해제의 조합을 사용한 암 치료 방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0509398B1 (de) * 1991-04-15 2001-09-19 Aventis Pharma Deutschland GmbH Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung
DE4342024A1 (de) * 1993-12-09 1995-06-14 Hoechst Ag Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid

Also Published As

Publication number Publication date
IL115641A0 (en) 1996-01-19
AU708293B2 (en) 1999-07-29
ZA958783B (en) 1996-05-09
MY132057A (en) 2007-09-28
TW328954B (en) 1998-04-01
HRP950524B1 (en) 2002-06-30
SI9500329A (en) 1996-04-30
CZ271295A3 (en) 1996-08-14
HK1011988A1 (en) 1999-07-23
JPH08225544A (ja) 1996-09-03
PT708093E (pt) 2001-06-29
FI954946L (fi) 1996-04-20
GR3035673T3 (en) 2001-06-29
NZ280258A (en) 1997-09-22
NO954139D0 (no) 1995-10-18
PL311016A1 (en) 1996-04-29
CN1094930C (zh) 2002-11-27
HRP950524A2 (en) 1997-10-31
CA2160859A1 (en) 1996-04-20
SK128495A3 (en) 1996-06-05
NO306615B1 (no) 1999-11-29
PL184860B1 (pl) 2003-01-31
EP0708093B1 (de) 2001-01-17
CN1135483A (zh) 1996-11-13
NO954139L (no) 1996-04-22
EP0708093A1 (de) 1996-04-24
ES2154311T3 (es) 2001-04-01
DE59508969D1 (de) 2001-02-22
FI954946A0 (fi) 1995-10-17
HU9503005D0 (en) 1995-12-28
HUT73485A (en) 1996-08-28
DK0708093T3 (da) 2001-04-30
ATE198747T1 (de) 2001-02-15
AU3431695A (en) 1996-05-02
KR960014108A (ko) 1996-05-22
US5723461A (en) 1998-03-03
DE4437406A1 (de) 1996-04-25

Similar Documents

Publication Publication Date Title
BR9504456A (pt) Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao
ZA918331B (en) Antimicrobial agents as well as substituted 2-cyclohexan-1-yl-amine derivatives and their preparation
KR890701566A (ko) 헤테로사이클릭 화합물
BR9503536A (pt) Composto processo para sua preparação seu uso e composição farmacêutica
DE3882544D1 (de) Substituierte 3,4-dihydro-2h-benzopyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
HRP960077B1 (en) Substituted benzenesulfonylureas and -thioureas, process for their preparation, their use as medicinal or diagnostic agent as well as medicaments containing them
PT99468A (pt) Processo para a preparacao de compostos cefem 7-actil-3-(carbamoiloxi substituido) com propriedades antibacterianas
FI923458A0 (fi) 4,5-cykloalkano-3-benzazepin-7-ol- derivat och deras anvaendning.
TW216795B (en) 3-substituted methyl-2,3-dihydroimidazo[1,2-c]quinazoline derivatives, the preparation and use thereof
DE3869144D1 (de) 5-(3-alkyl-5-tert.butyl-4-hydroxyphenyl)-2-amino-6h-1,3,4-thiadiazine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung.
ATE15045T1 (de) Cephalosporinderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate.
EP0487996B1 (de) 3-substituierte Cephalosporine, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
HUT76480A (en) Alkyl-5-methyl-sulphonyl-benzoyl-guanidine derivatives, process for the preparation thereof and pharmaceutical compositions containing them
AU683148B2 (en) Cyclohexane derivatives, process for their preparation, and the use of the compounds for the treatment of diseases
DE69002340D1 (de) Pyrimidin-derivate, 2-(4-(alpha-heteroaryl-alpha-aryl-(alpha-alkyl)-methoxy)-butyl)-1-piperazinyl) mit serotoninergischer wirkung.
ES8602797A1 (es) Procedimiento para preparar 11-piperazinil-5h-imidazo(2, 1-c) (1, 4) benzodiazepinas
DE69403896D1 (de) 4-amino-2-(hetero)aryl-butanamide verwenbar als 5-ht1a-antagonisten
ES2063328T3 (es) Nuevo uso de naftoxazinas.
ES464729A1 (es) Un procedimiento para la preparacion de benzisotiazolonas amino-alquil sustituidas.
DE59104473D1 (de) Arzneimittel welche substituierte 2-Cyclohexen-1yl-amin-Derivate enthalten und ihre Verwendung zur Bekämpfung von Krankheiten.
ES459475A1 (es) Procedimiento para la preparacion de nuevas 9-alcohilamino- eritromicina.

Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
PC Transfer

Free format text: AVENTIS PHARMA DEUTSCHLAND GMBH (DE)

HJEG Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
FG9A Patent or certificate of addition granted
B24C Patent annual fee: request for for restoration

Free format text: REFERENTE 9A., 10A., 11A., 12A., 13A., E 14A. ANUIDADES.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2049 DE 13/04/2010 E COMPROVAR RECOLHIMENTO DA 15A , 16A , 17A E 18A ANUIDADES.