BR9504456A - Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao - Google Patents
Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçaoInfo
- Publication number
- BR9504456A BR9504456A BR9504456A BR9504456A BR9504456A BR 9504456 A BR9504456 A BR 9504456A BR 9504456 A BR9504456 A BR 9504456A BR 9504456 A BR9504456 A BR 9504456A BR 9504456 A BR9504456 A BR 9504456A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- medicine
- compounds
- alkoxy
- formula
- Prior art date
Links
- 238000000034 method Methods 0.000 title 2
- 150000001875 compounds Chemical class 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- XSCHRSMBECNVNS-UHFFFAOYSA-N quinoxaline Chemical compound N1=CC=NC2=CC=CC=C21 XSCHRSMBECNVNS-UHFFFAOYSA-N 0.000 abstract 2
- 125000005092 alkenyloxycarbonyl group Chemical group 0.000 abstract 1
- 125000004453 alkoxycarbonyl group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004414 alkyl thio group Chemical group 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/38—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
- C07D241/40—Benzopyrazines
- C07D241/44—Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Dental Preparations (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4437406A DE4437406A1 (de) | 1994-10-19 | 1994-10-19 | Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9504456A true BR9504456A (pt) | 1997-05-20 |
Family
ID=6531202
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9504456A BR9504456A (pt) | 1994-10-19 | 1995-10-19 | Compostos e processo para sua preparaçao seu uso e medicamento e processo para sua preparaçao |
Country Status (28)
Country | Link |
---|---|
US (1) | US5723461A (pt) |
EP (1) | EP0708093B1 (pt) |
JP (1) | JPH08225544A (pt) |
KR (1) | KR960014108A (pt) |
CN (1) | CN1094930C (pt) |
AT (1) | ATE198747T1 (pt) |
AU (1) | AU708293B2 (pt) |
BR (1) | BR9504456A (pt) |
CA (1) | CA2160859A1 (pt) |
CZ (1) | CZ271295A3 (pt) |
DE (2) | DE4437406A1 (pt) |
DK (1) | DK0708093T3 (pt) |
ES (1) | ES2154311T3 (pt) |
FI (1) | FI954946L (pt) |
GR (1) | GR3035673T3 (pt) |
HK (1) | HK1011988A1 (pt) |
HR (1) | HRP950524B1 (pt) |
HU (1) | HUT73485A (pt) |
IL (1) | IL115641A0 (pt) |
MY (1) | MY132057A (pt) |
NO (1) | NO306615B1 (pt) |
NZ (1) | NZ280258A (pt) |
PL (1) | PL184860B1 (pt) |
PT (1) | PT708093E (pt) |
SI (1) | SI9500329A (pt) |
SK (1) | SK128495A3 (pt) |
TW (1) | TW328954B (pt) |
ZA (1) | ZA958783B (pt) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6369057B1 (en) * | 1991-04-15 | 2002-04-09 | Aventis Pharma Deutschland Gmbh | Quinoxalines, processes for their preparation and their use |
US6015800A (en) * | 1997-09-03 | 2000-01-18 | Warner-Lambert Company | Substituted quinoxaline-2-ones as glutamate receptor antagonists |
WO1999025327A2 (en) * | 1997-11-14 | 1999-05-27 | Warner-Lambert Company | Small molecule intervention in hiv-1 replication |
GB9901795D0 (en) * | 1999-01-28 | 1999-03-17 | Glaxo Group Ltd | Chemical compounds |
GB9911887D0 (en) * | 1999-05-21 | 1999-07-21 | Glaxo Group Ltd | Methods and medicaments for post exposure prophylaxis of an hiv infection |
WO2002087500A2 (en) * | 2001-04-27 | 2002-11-07 | Newbiotics, Inc. | Viral enzyme activated prototoxophores and use of same to treat viral infections |
WO2005018531A2 (fr) * | 2003-08-26 | 2005-03-03 | 'chemical Diversity Research Institute', Ltd. | Compositions pharmaceutiques, composes azo-heterocycliques et procedes de fabrication et d'utilisation correspondants |
US7351709B2 (en) * | 2004-06-09 | 2008-04-01 | Wyeth | Estrogen receptor ligands |
BR112014026703B1 (pt) | 2012-04-24 | 2022-10-25 | Vertex Pharmaceuticals Incorporated | Inibidores de dna-pk e seus usos, composição farmacêutica e seus usos, e método de sensibilização de uma célula |
HRP20211855T1 (hr) | 2013-03-12 | 2022-03-04 | Vertex Pharmaceuticals Incorporated | Inhibitori dnk-pk |
LT3424920T (lt) | 2013-10-17 | 2020-08-10 | Vertex Pharmaceuticals Incorporated | (s)-n-metil-8-(1-((2`-metil-[4,5`-bipirimidin]-6-il)amino)propan-2-il)chinolin-4-karboksamido ir jo deuterintų darinių, kaip dnr-pk inhibitorių, bendri kristalai |
KR20190062485A (ko) | 2016-09-27 | 2019-06-05 | 버텍스 파마슈티칼스 인코포레이티드 | Dna-손상제 및 dna-pk 저해제의 조합을 사용한 암 치료 방법 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0509398B1 (de) * | 1991-04-15 | 2001-09-19 | Aventis Pharma Deutschland GmbH | Chinoxaline, Verfahren zu ihrer Herstellung und ihre Verwendung |
DE4342024A1 (de) * | 1993-12-09 | 1995-06-14 | Hoechst Ag | Kombinationspräparate, enthaltend ein Chinoxalin und ein Nukleosid |
-
1994
- 1994-10-19 DE DE4437406A patent/DE4437406A1/de not_active Withdrawn
-
1995
- 1995-10-12 DK DK95116094T patent/DK0708093T3/da active
- 1995-10-12 DE DE59508969T patent/DE59508969D1/de not_active Expired - Fee Related
- 1995-10-12 ES ES95116094T patent/ES2154311T3/es not_active Expired - Lifetime
- 1995-10-12 PT PT95116094T patent/PT708093E/pt unknown
- 1995-10-12 AT AT95116094T patent/ATE198747T1/de not_active IP Right Cessation
- 1995-10-12 EP EP95116094A patent/EP0708093B1/de not_active Expired - Lifetime
- 1995-10-15 IL IL11564195A patent/IL115641A0/xx unknown
- 1995-10-16 TW TW084110841A patent/TW328954B/zh active
- 1995-10-17 MY MYPI95003112A patent/MY132057A/en unknown
- 1995-10-17 CZ CZ952712A patent/CZ271295A3/cs unknown
- 1995-10-17 AU AU34316/95A patent/AU708293B2/en not_active Ceased
- 1995-10-17 FI FI954946A patent/FI954946L/fi unknown
- 1995-10-17 NZ NZ280258A patent/NZ280258A/en unknown
- 1995-10-17 SK SK1284-95A patent/SK128495A3/sk unknown
- 1995-10-17 US US08/544,290 patent/US5723461A/en not_active Expired - Fee Related
- 1995-10-18 HU HU9503005A patent/HUT73485A/hu unknown
- 1995-10-18 CN CN95120372A patent/CN1094930C/zh not_active Expired - Fee Related
- 1995-10-18 ZA ZA958783A patent/ZA958783B/xx unknown
- 1995-10-18 CA CA002160859A patent/CA2160859A1/en not_active Abandoned
- 1995-10-18 HR HR950524A patent/HRP950524B1/xx not_active IP Right Cessation
- 1995-10-18 KR KR1019950035876A patent/KR960014108A/ko not_active Abandoned
- 1995-10-18 NO NO954139A patent/NO306615B1/no not_active IP Right Cessation
- 1995-10-18 PL PL95311016A patent/PL184860B1/pl unknown
- 1995-10-19 SI SI9500329A patent/SI9500329A/sl unknown
- 1995-10-19 BR BR9504456A patent/BR9504456A/pt not_active IP Right Cessation
- 1995-10-19 JP JP7271019A patent/JPH08225544A/ja active Pending
-
1998
- 1998-12-12 HK HK98113241A patent/HK1011988A1/xx not_active IP Right Cessation
-
2001
- 2001-03-30 GR GR20010400523T patent/GR3035673T3/el not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FB36 | Technical and formal requirements: requirement - article 36 of industrial property law | ||
PC | Transfer |
Free format text: AVENTIS PHARMA DEUTSCHLAND GMBH (DE) |
|
HJEG | Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law | ||
FG9A | Patent or certificate of addition granted | ||
B24C | Patent annual fee: request for for restoration |
Free format text: REFERENTE 9A., 10A., 11A., 12A., 13A., E 14A. ANUIDADES. |
|
B21F | Lapse acc. art. 78, item iv - on non-payment of the annual fees in time |
Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 2049 DE 13/04/2010 E COMPROVAR RECOLHIMENTO DA 15A , 16A , 17A E 18A ANUIDADES. |