BR9500380A - Composto composição farmacêutica método para bloquear sítios do receptor de NMDA e método de tratamento de uma doença ou estado num manífero - Google Patents

Composto composição farmacêutica método para bloquear sítios do receptor de NMDA e método de tratamento de uma doença ou estado num manífero

Info

Publication number: BR9500380A
Authority: BR; Brazil
Prior art keywords: treating; manifer; disease; pct; condition
Prior art date: 1994-01-31

Application number

BR9500380A

Other languages

English (en)

Inventor

Todd W Butler

Bertrand L Chenard

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-31

Filing date

1995-01-30

Publication date

1995-10-17

1995-01-30 Application filed by Pfizer filed Critical Pfizer

1995-10-17 Publication of BR9500380A publication Critical patent/BR9500380A/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Diabetes (AREA)
Toxicology (AREA)
Hospice & Palliative Care (AREA)
Hematology (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Emergency Medicine (AREA)
Psychology (AREA)
Anesthesiology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Cosmetics (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines Containing Plant Substances (AREA)
Hydrogenated Pyridines (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

BR9500380A 1994-01-31 1995-01-30 Composto composição farmacêutica método para bloquear sítios do receptor de NMDA e método de tratamento de uma doença ou estado num manífero BR9500380A (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US18947994A	1994-01-31	1994-01-31

Publications (1)

Publication Number	Publication Date
BR9500380A true BR9500380A (pt)	1995-10-17

Family

ID=22697514

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
BR9408506A BR9408506A (pt)	1994-01-31	1994-11-21	Compostos neuroprotetores
BR9500380A BR9500380A (pt)	1994-01-31	1995-01-30	Composto composição farmacêutica método para bloquear sítios do receptor de NMDA e método de tratamento de uma doença ou estado num manífero

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
BR9408506A BR9408506A (pt)	1994-01-31	1994-11-21	Compostos neuroprotetores

Country Status (27)

Country	Link
US (1)	US5744483A (pt)
EP (1)	EP0741724B1 (pt)
JP (1)	JP2866743B2 (pt)
CN (1)	CN1048247C (pt)
AT (1)	ATE183184T1 (pt)
AU (1)	AU684568B2 (pt)
BR (2)	BR9408506A (pt)
CA (1)	CA2182101C (pt)
CO (1)	CO4230161A1 (pt)
CZ (1)	CZ286757B6 (pt)
DE (1)	DE69420053T2 (pt)
DK (1)	DK0741724T3 (pt)
EG (1)	EG20672A (pt)
ES (1)	ES2134361T3 (pt)
FI (1)	FI113769B (pt)
GR (1)	GR3031356T3 (pt)
HU (1)	HU221633B1 (pt)
IL (1)	IL112415A (pt)
MY (1)	MY111623A (pt)
NO (1)	NO309190B1 (pt)
NZ (1)	NZ275151A (pt)
PE (1)	PE43795A1 (pt)
PL (1)	PL179448B1 (pt)
RU (1)	RU2126404C1 (pt)
TW (1)	TW449591B (pt)
WO (1)	WO1995020587A1 (pt)
ZA (1)	ZA95692B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPH11509839A (ja) *	1995-09-15	1999-08-31	ファイザー・インコーポレーテッド	薬剤活性を有するフェノール誘導体
TW498067B (en) *	1996-07-19	2002-08-11	Hoffmann La Roche	4-hydroxy-piperidine derivatives
EP1674087A1 (en)	2000-10-02	2006-06-28	Pfizer Products Inc.	Prophylactic use of n-methyl-d-aspartate (NMDA) antagonists
ZA200108038B (en) *	2000-10-02	2003-04-01	Pfizer Prod Inc	Prophylactic use of n-methyl-d-asparrate (NMDA) antagonists.
SE0100902D0 (sv)	2001-03-15	2001-03-15	Astrazeneca Ab	Compounds
JP4864719B2 (ja) *	2003-11-26	2012-02-01	ファイザー・プロダクツ・インク	Ｇｓｋ−３インヒビターとしてのアミノピラゾール誘導体
RU2008115032A (ru)	2005-11-03	2009-12-10	Ф. Хоффманн-Ля Рош Аг (Ch)	Арилсульфонилхроманы в качестве ингибиторов 5-нт6
RU2448964C2 (ru) *	2006-01-20	2012-04-27	Шеринг Корпорейшн	КАРБОЦИКЛИЧЕСКИЕ И ГЕТЕРОЦИКЛИЧЕСКИЕ АРИЛСУЛЬФОНЫ, ИХ ПРИМЕНЕНИЕ И ФАРМАЦЕВТИЧЕСКАЯ КОМПОЗИЦИЯ НА ИХ ОСНОВЕ, ОБЛАДАЮЩАЯ СВОЙСТВАМИ ИНГИБИТОРА γ-СЕКРЕТАЗЫ
EP2522647B1 (en) *	2011-05-10	2014-04-30	DSM IP Assets B.V.	Process of separating chiral isomers of chroman compounds and their derivatives and precursors

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3294804A (en) *	1961-01-27	1966-12-27	Sterling Drug Inc	1-(3-hydroxy-3-phenylpropyl)-4-phenyl-4-propionoxy-piperidine
FR5733M (pt) *	1966-09-27	1968-01-22
GB1495526A (en) *	1974-05-31	1977-12-21	Beecham Group Ltd	Chroman derivatives
US4016281A (en) *	1975-02-22	1977-04-05	Merck Patent Gesellschaft Mit Beschrankter Haftung	Tetralone and indanone compounds
US4082755A (en) *	1977-02-14	1978-04-04	Janssen Pharmaceutica N.V.	1-[(Diarylmethyl)aminoalkyl]piperidimes
WO1980000152A1 (en) *	1978-07-03	1980-02-07	Sandoz Ag	3-aminopropoxy-aryl derivates,preparation and use thereof
US4358456A (en) *	1980-05-03	1982-11-09	John Wyeth & Brother Limited	Antipsychotic piperidinomethyl-indole derivatives
DE3045688A1 (de) *	1980-12-04	1982-07-08	C.H. Boehringer Sohn, 6507 Ingelheim	Neue 8-arylalkyl-3-phenyl-3-nortropanole, deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zu ihrer herstellung
ATE23718T1 (de) *	1981-09-25	1986-12-15	Beecham Group Plc	Benzopyran-verbindungen mit pharmazeutischer wirkung.
EP0093534A1 (en) *	1982-04-28	1983-11-09	Beecham Group Plc	Novel chromanols
GB8308064D0 (en) *	1983-03-24	1983-05-05	Beecham Group Plc	Active compounds
FR2581993B1 (fr) *	1985-05-14	1988-03-18	Synthelabo	Derives de (benzoyl-4 piperidino)-2 phenyl-1 alcanols, leur preparation et leur application en therapeutique
US4957928A (en) *	1986-06-26	1990-09-18	Ciba-Geigy Corporation	Hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds
US4968678A (en) *	1988-02-19	1990-11-06	Eli Lilly And Company	Tetrazole excitatory amino acid receptor antagonists
FR2640266B2 (fr) *	1988-07-12	1992-07-10	Synthelabo	Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
US4968878A (en) *	1989-02-07	1990-11-06	Transitions Research Corporation	Dual bumper-light curtain obstacle detection sensor
US4902695A (en) *	1989-02-13	1990-02-20	Eli Lilly And Company	Excitatory amino acid receptor antagonists
SK279476B6 (sk) *	1989-05-17	1998-11-04	Pfizer	Deriváty 2-piperidino a 2-pyrolidino-1-alkanolov a
HU222726B1 (hu) *	1990-02-06	2003-09-29	Pfizer, Inc.,	Piperidinszármazékok, eljárás elżállításukra és az ezeket tartalmazó gyógyszerkészítmények
US5192751A (en) *	1992-07-24	1993-03-09	Eli Lilly And Company	Use of competitive NMDA receptor antagonists in the treatment of urinary incontinence

1994
- 1994-11-21 AT AT94931668T patent/ATE183184T1/de not_active IP Right Cessation
- 1994-11-21 CA CA002182101A patent/CA2182101C/en not_active Expired - Fee Related
- 1994-11-21 EP EP94931668A patent/EP0741724B1/en not_active Expired - Lifetime
- 1994-11-21 US US08/687,542 patent/US5744483A/en not_active Expired - Fee Related
- 1994-11-21 DK DK94931668T patent/DK0741724T3/da active
- 1994-11-21 WO PCT/IB1994/000365 patent/WO1995020587A1/en active IP Right Grant
- 1994-11-21 JP JP7519959A patent/JP2866743B2/ja not_active Expired - Lifetime
- 1994-11-21 CZ CZ19962256A patent/CZ286757B6/cs not_active IP Right Cessation
- 1994-11-21 ES ES94931668T patent/ES2134361T3/es not_active Expired - Lifetime
- 1994-11-21 AU AU80663/94A patent/AU684568B2/en not_active Ceased
- 1994-11-21 CN CN94194940A patent/CN1048247C/zh not_active Expired - Fee Related
- 1994-11-21 PL PL94315681A patent/PL179448B1/pl unknown
- 1994-11-21 HU HU9602100A patent/HU221633B1/hu not_active IP Right Cessation
- 1994-11-21 DE DE69420053T patent/DE69420053T2/de not_active Expired - Fee Related
- 1994-11-21 BR BR9408506A patent/BR9408506A/pt not_active Application Discontinuation
- 1994-11-21 RU RU96117381A patent/RU2126404C1/ru not_active IP Right Cessation
- 1994-11-21 NZ NZ275151A patent/NZ275151A/en unknown
- 1994-11-22 TW TW083110873A patent/TW449591B/zh active
1995
- 1995-01-18 PE PE1995259688A patent/PE43795A1/es not_active Application Discontinuation
- 1995-01-23 IL IL11241595A patent/IL112415A/xx not_active IP Right Cessation
- 1995-01-27 MY MYPI95000224A patent/MY111623A/en unknown
- 1995-01-27 CO CO95003001A patent/CO4230161A1/es unknown
- 1995-01-28 EG EG6795A patent/EG20672A/xx active
- 1995-01-30 FI FI950403A patent/FI113769B/fi not_active IP Right Cessation
- 1995-01-30 BR BR9500380A patent/BR9500380A/pt not_active IP Right Cessation
- 1995-01-30 ZA ZA95692A patent/ZA95692B/xx unknown
1996
- 1996-07-30 NO NO963186A patent/NO309190B1/no unknown
1999
- 1999-09-29 GR GR990402449T patent/GR3031356T3/el unknown

Also Published As

Publication number	Publication date
CA2182101C (en)	1999-08-03
ZA95692B (en)	1996-07-30
IL112415A (en)	1999-07-14
RU2126404C1 (ru)	1999-02-20
FI113769B (fi)	2004-06-15
CO4230161A1 (es)	1995-10-19
TW449591B (en)	2001-08-11
CZ286757B6 (en)	2000-06-14
EP0741724A1 (en)	1996-11-13
DK0741724T3 (da)	1999-12-20
NO963186D0 (no)	1996-07-30
NO963186L (no)	1996-07-30
MY111623A (en)	2000-09-27
EG20672A (en)	1999-11-30
CN1142825A (zh)	1997-02-12
CZ225696A3 (en)	1997-01-15
ATE183184T1 (de)	1999-08-15
JP2866743B2 (ja)	1999-03-08
JPH09501698A (ja)	1997-02-18
CA2182101A1 (en)	1995-08-03
DE69420053D1 (de)	1999-09-16
ES2134361T3 (es)	1999-10-01
HUT75942A (en)	1997-05-28
PE43795A1 (es)	1995-12-09
FI950403A0 (fi)	1995-01-30
CN1048247C (zh)	2000-01-12
DE69420053T2 (de)	1999-11-25
IL112415A0 (en)	1995-03-30
HU221633B1 (hu)	2002-12-28
PL315681A1 (en)	1996-11-25
BR9408506A (pt)	1997-08-05
NZ275151A (en)	1998-02-26
WO1995020587A1 (en)	1995-08-03
FI950403A (fi)	1995-08-01
AU8066394A (en)	1995-08-15
GR3031356T3 (en)	2000-01-31
EP0741724B1 (en)	1999-08-11
PL179448B1 (pl)	2000-09-29
NO309190B1 (no)	2000-12-27
US5744483A (en)	1998-04-28
HU9602100D0 (en)	1996-09-30
AU684568B2 (en)	1997-12-18

Publication	Publication Date	Title
DE60316779D1 (de)	2007-11-22	Thiadiazolylpiperazinderivate geeignet für die behandlung bzw. prävention von schmerzen
DK0503440T3 (da)	1999-01-18	Sumatriptanholdige lægemidler
BR0110420A (pt)	2003-07-01	Agonistas muscarìnicos
BR9908510A (pt)	2000-11-21	Uso de um composto, composto, processo para a preparação de um composto, composição farmacêutica, e, processo de tratar um paciente que sofre de, ou em risco de, uma doença micobacteriana
BR9500380A (pt)	1995-10-17	Composto composição farmacêutica método para bloquear sítios do receptor de NMDA e método de tratamento de uma doença ou estado num manífero
IT1282736B1 (it)	1998-03-31	Uso di derivati del p-amminofenolo per preparare composizioni farmaceutiche utili nel trattamento di malattie neurodegenerative
HUP9902135A2 (hu)	1999-11-29	(+)-alfa-(2,3-Dimetoxi-fenil)-1-[2-(4-fluor-fenil)-etil]-4-piperidin-metanol alkalmazása depresszív és bipoláris rendellenességek kezelésére alkalmas gyógyszerkészítmény előállítására
BR9502072A (pt)	1996-04-09	Composto metodo para o tratamento de uma condiçao médica e composiçao farmaceutica
CA2473694A1 (en)	2003-07-31	Use of calmodulin to promote bone regeneration
DE60306503D1 (de)	2006-08-10	Statin-therapie zur verbesserung der aufrechterhaltung der kognitiven funktion
ES2105643T3 (es)	1997-10-16	Uso de la 2-(4-(4-clorofenil)ciclohexil)-3-hidroxi-1,4-naftoquinona para el tratamiento del cancer.
HUT57040A (en)	1991-11-28	Process for producing pharmaceutical compositions comprising 2-brackets open 4-(4-chlorophenyl)-cyclohexyl brackets closed-3-hydroxy-1,4-naphthoquinone suitable for treating toxoplasmosis
NO20091111L (no)	2001-04-25	Anvendelse av R(+)-alfa-(2,3-dimetoksyfenyl)-l-[2-(4-fluorfenyl)etyl]-4-piperidin-metanol for behandling av sovnforstyrrelser
FR2718965B1 (fr)	1996-05-24	Nouvelle application thérapeutique de la spiramycine.
RU97113692A (ru)	1999-07-20	Применение 3,4-дифенилхроманов для получения фармацевтической композиции для лечения или профилактики церебральных дегенеративных расстройств

Legal Events

Date	Code	Title	Description
2000-12-19	EG	Technical examination (opinion): publication of technical examination (opinion)
2001-05-29	FB36	Technical and formal requirements: requirement - article 36 of industrial property law
2001-09-18	HJEG	Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
2008-10-14	B08F	Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]	Free format text: REFERENTE A 11A,12A,13A E 14A ANUIDADES.
2009-04-22	B08K	Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]	Free format text: REFERENTE AO DESPACHO PUBLICADO NA RPI 1971 DE 14/10/2008.