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BR112015005056A2 - vacinas de combinação com sorogrupo b meningococcus e d/t/p - Google Patents

vacinas de combinação com sorogrupo b meningococcus e d/t/p

Info

Publication number
BR112015005056A2
BR112015005056A2 BR112015005056A BR112015005056A BR112015005056A2 BR 112015005056 A2 BR112015005056 A2 BR 112015005056A2 BR 112015005056 A BR112015005056 A BR 112015005056A BR 112015005056 A BR112015005056 A BR 112015005056A BR 112015005056 A2 BR112015005056 A2 BR 112015005056A2
Authority
BR
Brazil
Prior art keywords
combination vaccines
adjuvant
meningococcus
serogroup
dtp
Prior art date
Application number
BR112015005056A
Other languages
English (en)
Inventor
Baudner Barbara
O'hagan Derek
Singh Manmohan
Bufali Simone
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of BR112015005056A2 publication Critical patent/BR112015005056A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/095—Neisseria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6031—Proteins
    • A61K2039/6037—Bacterial toxins, e.g. diphteria toxoid [DT], tetanus toxoid [TT]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

resumo “vacinas de combinação com sorogrupo b meningococcus e d/t/p”. antígenos de sorogrupo b meningococcus podem, com sucesso, ser combinados com difteria, tétano e toxóide de tosse convulsa ("dtp") para proporcionar vacinas de combinação eficazes para proteger contra múltiplos patógenos. estas combinações são eficazes com uma faixa de diferentes adjuvantes, e com ambas as relações de dtp do tipo pediátrico e tipo de reforço. o adjuvante pode aumentar a resposta imune que provoca a composição; alternativamente, através da inclusão de um adjuvante que é possível para as composições para ter uma quantidade relativamente menor de antígeno, enquanto, no entanto, tendo imunogenicidade que é comparável às vacinas de combinação sem adjuvante.
BR112015005056A 2012-09-06 2013-09-06 vacinas de combinação com sorogrupo b meningococcus e d/t/p BR112015005056A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261697756P 2012-09-06 2012-09-06
PCT/EP2013/068414 WO2014037472A1 (en) 2012-09-06 2013-09-06 Combination vaccines with serogroup b meningococcus and d/t/p

Publications (1)

Publication Number Publication Date
BR112015005056A2 true BR112015005056A2 (pt) 2017-11-21

Family

ID=49117859

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015005056A BR112015005056A2 (pt) 2012-09-06 2013-09-06 vacinas de combinação com sorogrupo b meningococcus e d/t/p

Country Status (10)

Country Link
US (3) US9526776B2 (pt)
EP (1) EP2892553A1 (pt)
JP (1) JP6324961B2 (pt)
CN (1) CN104602705A (pt)
AU (1) AU2013311702A1 (pt)
BR (1) BR112015005056A2 (pt)
CA (1) CA2882619A1 (pt)
MX (1) MX2015002717A (pt)
RU (1) RU2015106930A (pt)
WO (1) WO2014037472A1 (pt)

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BR112012004806B8 (pt) 2009-09-02 2022-10-04 Novartis Ag composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso
US9315530B2 (en) 2010-09-01 2016-04-19 Novartis Ag Adsorption of immunopotentiators to insoluble metal salts
CA2828844C (en) 2011-03-02 2020-07-14 Novartis Ag Combination vaccines with lower doses of antigen and/or adjuvant
JP2014525429A (ja) * 2011-09-01 2014-09-29 ノバルティス アーゲー Ｓｔａｐｈｙｌｏｃｏｃｃｕｓａｕｒｅｕｓ抗原のアジュバント添加処方物
CA2866406A1 (en) 2012-03-08 2013-09-12 Novartis Ag Adjuvanted formulations of booster vaccines
RU2644340C2 (ru) 2012-06-14 2018-02-08 Новартис Аг Вакцины для менингококка серогруппы х
CN104602705A (zh) * 2012-09-06 2015-05-06 诺华股份有限公司 血清组b脑膜炎球菌和d/t/p的联合疫苗
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CN113395977A (zh) * 2018-12-05 2021-09-14 圣诺菲·帕斯图尔公司 百日咳加强疫苗

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US20150190493A1 (en) 2015-07-09
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AU2013311702A1 (en) 2015-02-19
JP2015529212A (ja) 2015-10-05
JP6324961B2 (ja) 2018-05-16
US20170100472A1 (en) 2017-04-13
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MX2015002717A (es) 2015-05-15
CN104602705A (zh) 2015-05-06

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