[go: up one dir, main page]

BR112013015503A2 - formulação localizada tópica, uso de uma formulação, e, método para tratamento ou profilaxia de infestação de parasita de um animal - Google Patents

formulação localizada tópica, uso de uma formulação, e, método para tratamento ou profilaxia de infestação de parasita de um animal

Info

Publication number
BR112013015503A2
BR112013015503A2 BR112013015503A BR112013015503A BR112013015503A2 BR 112013015503 A2 BR112013015503 A2 BR 112013015503A2 BR 112013015503 A BR112013015503 A BR 112013015503A BR 112013015503 A BR112013015503 A BR 112013015503A BR 112013015503 A2 BR112013015503 A2 BR 112013015503A2
Authority
BR
Brazil
Prior art keywords
formulation
prophylaxing
animal
treating
parasite infestation
Prior art date
Application number
BR112013015503A
Other languages
English (en)
Inventor
Regina Heckeroth Anja
Zoller Hartmut
Williams Heike
Müller Ramona
Fuchs Stefan
Original Assignee
Intervet Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43971048&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112013015503(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Intervet Int Bv filed Critical Intervet Int Bv
Publication of BR112013015503A2 publication Critical patent/BR112013015503A2/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/80—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/366—Lactones having six-membered rings, e.g. delta-lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A61K9/0017—Non-human animal skin, e.g. pour-on, spot-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/14—Ectoparasiticides, e.g. scabicides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Environmental Sciences (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
BR112013015503A 2010-12-27 2011-12-22 formulação localizada tópica, uso de uma formulação, e, método para tratamento ou profilaxia de infestação de parasita de um animal BR112013015503A2 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10197089 2010-12-27
US201161430240P 2011-01-06 2011-01-06
PCT/EP2011/073828 WO2012089622A2 (en) 2010-12-27 2011-12-22 Topical localized isoxazoline formulation

Publications (1)

Publication Number Publication Date
BR112013015503A2 true BR112013015503A2 (pt) 2017-06-27

Family

ID=43971048

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112013015503A BR112013015503A2 (pt) 2010-12-27 2011-12-22 formulação localizada tópica, uso de uma formulação, e, método para tratamento ou profilaxia de infestação de parasita de um animal

Country Status (18)

Country Link
US (4) US9173870B2 (pt)
EP (1) EP2658542B1 (pt)
JP (3) JP6002148B2 (pt)
KR (2) KR20130130761A (pt)
CN (2) CN103260621B (pt)
AU (2) AU2016201954B2 (pt)
BR (1) BR112013015503A2 (pt)
CA (1) CA2822839C (pt)
DK (1) DK2658542T3 (pt)
ES (1) ES2908094T3 (pt)
HU (1) HUE058291T2 (pt)
MX (2) MX356926B (pt)
NZ (1) NZ611476A (pt)
PL (1) PL2658542T3 (pt)
PT (1) PT2658542T (pt)
RU (2) RU2749733C2 (pt)
WO (1) WO2012089622A2 (pt)
ZA (1) ZA201304514B (pt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2011351579B2 (en) * 2010-12-27 2016-04-21 Intervet International B.V. Topical localized isoxazoline formulation comprising glycofurol
WO2012089622A2 (en) 2010-12-27 2012-07-05 Intervet International B.V. Topical localized isoxazoline formulation
EA026947B1 (ru) 2011-09-12 2017-06-30 Мериал, Инк. Пестицидные композиции, содержащие изоксазолиновый активный ингредиент, и способы их применения
MX351702B (es) 2012-02-06 2017-10-25 Merial Inc Composiciones veterinarias orales parasiticidas que comprenden agentes activos de accion sistemica, metodos y usos de las mismas.
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
EP2833866B2 (en) * 2012-04-04 2024-11-27 Intervet International B.V. Soft chewable pharmaceutical products
KR102341193B1 (ko) 2013-11-01 2021-12-17 뵈링거 잉겔하임 애니멀 헬스 유에스에이 인코포레이티드 구충 및 살충성의 이속사졸린 화합물
JP6506763B2 (ja) 2013-12-20 2019-04-24 インターベット インターナショナル ベー． フェー． 家禽類における節足動物侵襲の処置または予防のためのイソオキサゾリン誘導体の使用
CN105813651B (zh) 2013-12-20 2021-11-23 英特维特国际股份有限公司 异噁唑啉组合物及其在预防或治疗动物的寄生虫侵袭中的用途
EP3131398B1 (en) 2014-04-17 2019-10-23 Boehringer Ingelheim Animal Health USA Inc. Use of malononitrile compounds for protecting animals from parasites
WO2016022066A1 (en) 2014-08-04 2016-02-11 Jerry Tan Eye Surgery Pte Ltd Pharmaceutical compositions for demodex related blepharitis and eyelid crusting
BR112017013286A2 (pt) 2014-12-22 2018-03-06 Intervet International B.V. composto de isoxazolina, e, uso de um composto de isoxazolina.
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
WO2016187534A1 (en) 2015-05-20 2016-11-24 Merial, Inc. Anthelmintic depsipeptide compounds
US20170333305A1 (en) * 2016-05-23 2017-11-23 Microban Products Company Topical skin product having retention property
BR112019007605A2 (pt) 2016-10-14 2019-09-17 Boehringer Ingelheim Animal Health Usa Inc compostos pesticidas e parasiticidas de vinil isoxazolina
US11382949B2 (en) 2016-11-16 2022-07-12 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic depsipeptide compounds
WO2019036407A1 (en) 2017-08-14 2019-02-21 Merial, Inc. PYRAZOLE-ISOXAZOLINE COMPOUNDS WITH PESTICIDE AND PARASITICIDE ACTIVITY
EP3713567A1 (en) * 2017-11-23 2020-09-30 Ceva Sante Animale Composition containing moxidectin for treating parasites infestations
CN119174758A (zh) 2017-12-15 2024-12-24 塔苏斯制药有限公司 用于治疗睑炎的异恶唑啉驱虫剂制剂和方法
AR113997A1 (es) 2017-12-21 2020-07-08 Intervet Int Bv Composiciones antiparasitarias para unción dorsal continua
BR112021000257A2 (pt) 2018-07-09 2021-04-06 Boehringer Ingelheim Animal Health USA Inc. Compostos heterocíclicos anti-helmínticos
EP3883648A1 (en) 2018-11-20 2021-09-29 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
KR102079347B1 (ko) * 2018-11-30 2020-02-19 문현규 치과용 유닛 체어
AR118435A1 (es) 2019-03-19 2021-10-06 Boehringer Ingelheim Animal Health Usa Inc Compuestos de aza-benzotiofeno y aza-benzofurano como antihelmínticos
US20220296564A1 (en) 2019-05-03 2022-09-22 Intervet Inc. Injectable pharmaceutical compositions and uses thereof
FR3107531B1 (fr) * 2020-02-20 2022-02-25 Rl Innovation .composition liquide ou en gel, ecologique permettant l’enlevement des graffittis, chewing-gums, colles, resines sur tous supports poreux ou non ainsi que tous marquages routier
CN116249704A (zh) 2020-05-29 2023-06-09 勃林格殷格翰动物保健美国公司 驱虫用杂环化合物
CH717763A2 (de) 2020-08-18 2022-02-28 Swibox Ag Abzweigsystem für elektrische Leiter.
BR112023015168A2 (pt) 2021-01-27 2023-10-03 Corteva Agriscience Llc Compostos de ciclopropilamida contra parasitas em peixes
US20240116854A1 (en) 2021-01-27 2024-04-11 Intervet Inc. Cyclopropylamide compounds against parasites in fish
EP4479317A1 (en) 2022-02-17 2024-12-25 Boehringer Ingelheim Vetmedica GmbH Method and system for providing a fluid product mailer
NO20240925A1 (en) 2023-09-15 2025-03-17 Evah Atlantic Inc Dihydroisoxazole compound for use in reducing ectoparasite infestations on fish

Family Cites Families (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950360A (en) 1972-06-08 1976-04-13 Sankyo Company Limited Antibiotic substances
US3984564A (en) 1972-06-08 1976-10-05 Sankyo Company Limited Antibiotic substances B-41, their production and their use as insecticides and acaricides
JPS60218303A (ja) * 1984-04-13 1985-11-01 Mitsubishi Chem Ind Ltd 忌避剤組成物
US4916154A (en) 1986-09-12 1990-04-10 American Cyanamid Company 23-Imino derivatives of LL-F28249 compounds
IL98599A (en) 1990-06-28 1995-06-29 Merck & Co Inc Stable salts of 4"-deoxy-4"-epi-methylamino avermectin b1a/b1b and insecticidal compositions containing them
JPH04217606A (ja) * 1990-11-30 1992-08-07 Mitsubishi Gas Chem Co Inc 吸血害虫の吸血阻害剤
US5874479A (en) 1991-03-01 1999-02-23 Warner-Lambert Company Therapeutic permeation enhanced-wound healing compositions and methods for preparing and using same
US5399717A (en) 1993-09-29 1995-03-21 Merck & Co., Inc. Glycosidation route to 4"-epi-methylamino-4"-deoxyavermectin B1
GB0115996D0 (en) 2001-06-29 2001-08-22 Nokia Corp Circuit-switched and packet-switched communications
US7906128B2 (en) * 2002-10-21 2011-03-15 Wyeth Llc Use of neuronal sodium channel antagonists for the control of ectoparasites in homeothermic animals
US8119150B2 (en) * 2002-10-25 2012-02-21 Foamix Ltd. Non-flammable insecticide composition and uses thereof
KR101137785B1 (ko) 2003-07-18 2012-04-25 백스터 인터내셔널 인코포레이티드 제어된 상 분리에 의해 제조된 작은 구형 입자의 제조방법, 이용 방법 및 조성물
US7422215B2 (en) 2003-10-08 2008-09-09 Seven Generations, Inc. Biased card deal
AU2005219788B2 (en) 2004-03-05 2010-06-03 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and noxious organism control agent
PE20060785A1 (es) * 2004-10-08 2006-09-19 Wyeth Corp Composiciones de amitraz
UA86649C2 (ru) * 2004-10-08 2009-05-12 Уайет Протипаразитарная композиция, способ ее получения и способ лечения
US7749527B2 (en) 2005-05-24 2010-07-06 Wyeth Llc Gel compositions for control of ecto-parasites
US20060293260A1 (en) 2005-05-24 2006-12-28 Wyeth Useful high load concentrate compositions for control of ecto-and endo-parasites
TWI368505B (en) 2005-05-24 2012-07-21 Wyeth Corp Versatile high load concentrate compositions for control of ecto-parasites
TWI412322B (zh) 2005-12-30 2013-10-21 Du Pont 控制無脊椎害蟲之異唑啉
US8093429B2 (en) 2006-05-31 2012-01-10 National University Corporation Hokkaido University Fluoroamine having perfluoroalkyl group, process for producing the same, method of fluorination therewith, and method of recovering amide having perfluoroalkyl group
TW200846029A (en) 2007-02-09 2008-12-01 Wyeth Corp High dose, long-acting ectoparasiticide for extended control
CL2008001614A1 (es) 2007-06-05 2008-08-08 Wyeth Corp Composicion parasiticida veterinaria que comprende un disolvente que no contiene hidroxilo, un estabilizador, amitraz y opcionalmente una lactona macrociclica y miristato de isopropilo; y su uso para tratar o controlar una infestacion o infeccion par
TWI430995B (zh) 2007-06-26 2014-03-21 Du Pont 萘異唑啉無脊椎有害動物控制劑
MX361762B (es) 2007-06-27 2018-12-17 Du Pont Metodo de control de plagas en animales.
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
EP2379544B1 (en) 2008-12-18 2013-10-16 Novartis AG Isoxazolines derivatives and their use as pesticide
TWI454472B (zh) 2008-12-19 2014-10-01 Novartis Ag 有機化合物
BRPI1008403A2 (pt) * 2009-02-23 2015-08-25 Wyeth Llc Formulação ectoparasiticida de odor melhorado
SI2513104T1 (sl) 2009-12-17 2016-07-29 Merial, Inc. Antiparazitske dihidroazolne spojine in sestavki, ki jih obsegajo
CN101780020B (zh) * 2010-02-09 2011-12-28 广东名臣有限公司 一种清凉、止痒、驱蚊的花露水
EP2556060A1 (en) 2010-04-08 2013-02-13 Ah Usa 42 Llc Substituted 3,5- diphenyl-isoxazoline derivatives as insecticides and acaricides
WO2012089622A2 (en) * 2010-12-27 2012-07-05 Intervet International B.V. Topical localized isoxazoline formulation
AU2011351579B2 (en) 2010-12-27 2016-04-21 Intervet International B.V. Topical localized isoxazoline formulation comprising glycofurol
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments

Also Published As

Publication number Publication date
US20180085352A1 (en) 2018-03-29
CN103260621B (zh) 2016-08-24
US9532978B2 (en) 2017-01-03
ZA201304514B (en) 2014-03-26
US20170071914A1 (en) 2017-03-16
MX2013007500A (es) 2013-08-01
US20160015689A1 (en) 2016-01-21
WO2012089622A3 (en) 2012-11-15
NZ611476A (en) 2015-10-30
AU2016201954A1 (en) 2016-04-21
EP2658542A2 (en) 2013-11-06
JP2016222691A (ja) 2016-12-28
AU2011351578A1 (en) 2013-06-20
HUE058291T2 (hu) 2022-07-28
JP6246864B2 (ja) 2017-12-13
AU2016201954B2 (en) 2017-11-23
CN105616406A (zh) 2016-06-01
AU2017254818A1 (en) 2017-11-16
KR102027723B1 (ko) 2019-10-01
RU2017118161A3 (pt) 2020-07-30
MX356926B (es) 2018-06-19
US20130281501A1 (en) 2013-10-24
US9173870B2 (en) 2015-11-03
CN103260621A (zh) 2013-08-21
CA2822839C (en) 2020-12-29
US10864195B2 (en) 2020-12-15
RU2013135280A (ru) 2015-02-10
CN105616406B (zh) 2019-12-13
CA2822839A1 (en) 2012-07-05
KR20180125037A (ko) 2018-11-21
WO2012089622A2 (en) 2012-07-05
DK2658542T3 (da) 2022-03-28
JP2014504586A (ja) 2014-02-24
PL2658542T3 (pl) 2022-06-20
KR20130130761A (ko) 2013-12-02
JP6514754B2 (ja) 2019-05-15
RU2633061C2 (ru) 2017-10-11
AU2017254818B2 (en) 2019-08-01
MX383895B (es) 2025-03-14
RU2749733C2 (ru) 2021-06-16
RU2017118161A (ru) 2018-10-30
ES2908094T3 (es) 2022-04-27
EP2658542B1 (en) 2022-01-26
JP6002148B2 (ja) 2016-10-05
PT2658542T (pt) 2022-03-10
JP2018048194A (ja) 2018-03-29

Similar Documents

Publication Publication Date Title
BR112013015503A2 (pt) formulação localizada tópica, uso de uma formulação, e, método para tratamento ou profilaxia de infestação de parasita de um animal
BR112013015498A2 (pt) formulação localizada tópica, uso da formulação, e, método para tratamento ou profilaxia de infestação de parasita de um animal
BR112014010186A2 (pt) formulação farmacêutica estável, kit, composição farmacêutica, método para preparar uma formulação farmacêutica, e, método para tratar um humano ou animal
BR112015010772A2 (pt) composição de enxágue tópica, uso de uma composição e método para tratar ou melhorar a pele de um indivíduo contra a acne
BR112014011671A2 (pt) composto, composição farmacêutica, método para o tratamento de uma doença ou condição, e, uso de um composto
BR112014010206A2 (pt) composto, composição farmacêutica, uso de composto, e, método para a profilaxia ou tratamento de um estado ou condição de doença
BR112014003681A2 (pt) composto, composição farmacêutica, produto de combinação farmacêutica, uso de um composto, e, método para tratar doenças ou condições
BR112013020352A2 (pt) composto, composição farmacêutica, uso de um composto e método para tratar doença ou condição mediana por rorgamat num indivíduo
BR112015003332A2 (pt) composto, composição farmacêutica, uso do composto e método para tratar uma doença ou condição mediada por rorgammat em um paciente
BR112015003398A2 (pt) composto, composição farmacêutica, uso do composto e método para tratar uma doença ou condição mediada por rorgammat em um paciente
BR112014010179A2 (pt) composto, composição farmacêutica, uso de um composto, e, método para a profilaxia ou tratamento de um estado ou condição
BR112012022878A2 (pt) composto, composição farmacêutica, uso do compostos e método de tratamento
BR112014010177A2 (pt) composto, composição farmacêutica, uso do composto, e, método para a profilaxia ou tratamento de um estado ou uma condição de doença
BR112012026570A2 (pt) composto, composição farmacêutica, uso de um composto, método para o tratamento de um indíviduo e produto combinado
BRPI0820568A2 (pt) Composto, composição farmacêutica, uso de um composto ou uma composição farmacêutica, e, método de tratamento de um humano ou animal
BR112012022879A2 (pt) composto, composição farmacêutica, uso do composto e método de tratamento
BRPI0907977A2 (pt) Composto, composição farmacêutica, uso de um composto, e, método para tratar ou prevenir doenças
BR112012029746A2 (pt) composição para tratamento da pele, método para fornecer um efeito microbicida para pele e uso de uma combinação
BR112012010859A2 (pt) ''composto,formulação farmacêutica,processo de preparação de um composto,uso de um composto e método de tratamento ou profilaxia de distúrbio proliferativos celulares''
BR112013003529A2 (pt) "composição aerada, composição de tratamento capilar método para o tratamento capilar"
BR112014010162A8 (pt) uso de composição, método para melhorar o reconhecimento e/ou tratar ou prevenir função de reconhecimento prejudicada em um indivíduo, e composição
BR112012028719A2 (pt) composição de tratamento de superfície dura, método para fornecer um efeito antimicrobiano a uma superfície dura e uso de uma combinação
BR112012020719A2 (pt) formulação herbicida método de tratamento de plantas com herbicida método de aumento da eficácia de uma formulação herbicida, e, uso de uma composição
BR112012026707A2 (pt) uso de um anticorpo anti-cd20 afucosilado, composição que compreende um anticorpo anti-cd20 afucosilado e método de tratamento de pacientes que sofrem de câncer por meio da administração de um anticorpo anti-cd20 afucosilado
BRPI0907974A2 (pt) Composto, composição farmacêutica, uso de um composto, e, método para tratar ou prevenir doenças

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]