BR112012026112A2 - método de tratar obesidade usando moduladores de inflamação antioxidantes - Google Patents
método de tratar obesidade usando moduladores de inflamação antioxidantesInfo
- Publication number
- BR112012026112A2 BR112012026112A2 BR112012026112A BR112012026112A BR112012026112A2 BR 112012026112 A2 BR112012026112 A2 BR 112012026112A2 BR 112012026112 A BR112012026112 A BR 112012026112A BR 112012026112 A BR112012026112 A BR 112012026112A BR 112012026112 A2 BR112012026112 A2 BR 112012026112A2
- Authority
- BR
- Brazil
- Prior art keywords
- antioxidant inflammation
- inflammation modulators
- treating obesity
- treating
- antioxidant
- Prior art date
Links
- 206010061218 Inflammation Diseases 0.000 title abstract 3
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 239000003963 antioxidant agent Substances 0.000 title abstract 3
- 230000003078 antioxidant effect Effects 0.000 title abstract 3
- 230000004054 inflammatory process Effects 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 229950002483 bardoxolone Drugs 0.000 abstract 1
- -1 methyl bardoxolone Chemical compound 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/275—Nitriles; Isonitriles
- A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Child & Adolescent Psychology (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
Abstract
método de tratar obesidade usando moduladores de inflamação antioxidantes. a presente invenção refere-se a métodos de tratar e/ou previnir obesidade compreendendo a administração de moduladores de inflamação antioxidantes descritos aqui, incluindo, por exemplo, bardoxolona metila.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32327610P | 2010-04-12 | 2010-04-12 | |
US61/323,276 | 2010-04-12 | ||
US38909010P | 2010-10-01 | 2010-10-01 | |
US61/389,090 | 2010-10-01 | ||
PCT/US2011/032156 WO2011130302A2 (en) | 2010-04-12 | 2011-04-12 | Method of treating obesity using antioxidant inflammation modulators |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112012026112A2 true BR112012026112A2 (pt) | 2016-06-28 |
BR112012026112B1 BR112012026112B1 (pt) | 2020-03-17 |
Family
ID=44259866
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112012026112-6A BR112012026112B1 (pt) | 2010-04-12 | 2011-04-12 | Uso de compostos moduladores de inflamação antioxidantes e composição farmacêutica |
Country Status (31)
Country | Link |
---|---|
US (3) | US10105372B2 (pt) |
EP (1) | EP2558105B1 (pt) |
JP (1) | JP5990160B2 (pt) |
KR (1) | KR101819699B1 (pt) |
CN (1) | CN102939089B (pt) |
AU (1) | AU2011240690C1 (pt) |
BR (1) | BR112012026112B1 (pt) |
CA (1) | CA2795320C (pt) |
CL (1) | CL2012002859A1 (pt) |
CY (1) | CY1122480T1 (pt) |
DK (1) | DK2558105T3 (pt) |
EA (1) | EA026567B1 (pt) |
ES (1) | ES2768204T3 (pt) |
HR (1) | HRP20192291T1 (pt) |
HU (1) | HUE047994T2 (pt) |
IL (1) | IL222273B (pt) |
LT (1) | LT2558105T (pt) |
ME (1) | ME03713B (pt) |
MX (1) | MX357596B (pt) |
MY (1) | MY163031A (pt) |
NZ (1) | NZ602826A (pt) |
PH (1) | PH12012502041B1 (pt) |
PL (1) | PL2558105T3 (pt) |
PT (1) | PT2558105T (pt) |
RS (1) | RS59850B1 (pt) |
SG (2) | SG10201808661XA (pt) |
SI (1) | SI2558105T1 (pt) |
SM (1) | SMT202000086T1 (pt) |
TW (1) | TWI558724B (pt) |
WO (1) | WO2011130302A2 (pt) |
ZA (1) | ZA201207518B (pt) |
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CN108290922B (zh) | 2015-09-23 | 2021-12-07 | 里亚塔医药公司 | 用于抑制il-17和其它用途的c4-改性的齐墩果酸衍生物 |
KR20190050800A (ko) * | 2016-09-08 | 2019-05-13 | 레제네라 파마 리미티드 | 트리테르페노이드를 포함하는 조성물 및 시신경병증을 치료하기 위한 이의 용도 |
BR112019009256A2 (pt) | 2016-11-08 | 2019-07-16 | Reata Pharmaceuticals Inc | métodos para tratar síndrome de alport usando bardoxolona metil ou análogos do mesmo |
TWI831738B (zh) | 2016-12-16 | 2024-02-11 | 美商瑞塔醫藥有限責任公司 | 用於抑制RORγ及其他用途的嘧啶三環烯酮衍生物 |
US11993574B2 (en) | 2018-06-15 | 2024-05-28 | Reata Pharmaceuticals, Inc | Pyrazole and imidazole compounds for inhibition of IL-17 and RORgamma |
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2011
- 2011-04-12 LT LTEP11715645.5T patent/LT2558105T/lt unknown
- 2011-04-12 EA EA201291031A patent/EA026567B1/ru not_active IP Right Cessation
- 2011-04-12 AU AU2011240690A patent/AU2011240690C1/en active Active
- 2011-04-12 ME MEP-2020-4A patent/ME03713B/me unknown
- 2011-04-12 SG SG10201808661XA patent/SG10201808661XA/en unknown
- 2011-04-12 PT PT117156455T patent/PT2558105T/pt unknown
- 2011-04-12 RS RS20200073A patent/RS59850B1/sr unknown
- 2011-04-12 SG SG2012075834A patent/SG184830A1/en unknown
- 2011-04-12 CN CN201180028997.6A patent/CN102939089B/zh active Active
- 2011-04-12 EP EP11715645.5A patent/EP2558105B1/en active Active
- 2011-04-12 DK DK11715645.5T patent/DK2558105T3/da active
- 2011-04-12 KR KR1020127029558A patent/KR101819699B1/ko active Active
- 2011-04-12 SI SI201131840T patent/SI2558105T1/sl unknown
- 2011-04-12 TW TW100112717A patent/TWI558724B/zh not_active IP Right Cessation
- 2011-04-12 PH PH1/2012/502041A patent/PH12012502041B1/en unknown
- 2011-04-12 ES ES11715645T patent/ES2768204T3/es active Active
- 2011-04-12 NZ NZ602826A patent/NZ602826A/en unknown
- 2011-04-12 BR BR112012026112-6A patent/BR112012026112B1/pt active IP Right Grant
- 2011-04-12 SM SM20200086T patent/SMT202000086T1/it unknown
- 2011-04-12 WO PCT/US2011/032156 patent/WO2011130302A2/en active Application Filing
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