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BR0314265A - Dispositivo médico implantável com um revestimento de fosfato de cálcio e processo de revestir um dispositivo médico implantável e um dispositivo implantável de tecido macio com um revestimento de fosfato de cálcio - Google Patents

Dispositivo médico implantável com um revestimento de fosfato de cálcio e processo de revestir um dispositivo médico implantável e um dispositivo implantável de tecido macio com um revestimento de fosfato de cálcio

Info

Publication number
BR0314265A
BR0314265A BR0314265-5A BR0314265A BR0314265A BR 0314265 A BR0314265 A BR 0314265A BR 0314265 A BR0314265 A BR 0314265A BR 0314265 A BR0314265 A BR 0314265A
Authority
BR
Brazil
Prior art keywords
calcium phosphate
implantable medical
coating
medical device
deposition process
Prior art date
Application number
BR0314265-5A
Other languages
English (en)
Inventor
Tomasz Troczynsky
Dorna Hakimi
Buhsung Hyun
Mehrdad Keshmiri
Mao-Jung Maurice Lien
Arc Rajtar
Douglas Smith
Pui Hung Manus Tsui
Quanzu Yang
Original Assignee
Univ British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=31994107&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0314265(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ British Columbia filed Critical Univ British Columbia
Publication of BR0314265A publication Critical patent/BR0314265A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08Materials for coatings
    • A61L31/082Inorganic materials
    • A61L31/086Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28Materials for coating prostheses
    • A61L27/30Inorganic materials
    • A61L27/32Phosphorus-containing materials, e.g. apatite
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/56Porous materials, e.g. foams or sponges
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146Porous materials, e.g. foams or sponges

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Transplantation (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Surgery (AREA)
  • Vascular Medicine (AREA)
  • Materials For Medical Uses (AREA)

Abstract

"DISPOSITIVO MéDICO IMPLANTáVEL COM UM REVESTIMENTO DE FOSFATO DE CáLCIO E PROCESSO DE REVESTIR UM DISPOSITIVO MéDICO IMPLANTáVEL E UM DISPOSITIVO IMPLANTáVEL DE TECIDO MACIO COM UM REVESTIMENTO DE FOSFATO DE CáLCIO". Esta invenção refere-se a dispositivos médicos implantáveis revestidos de fosfato de cálcio inéditos. Os revestimentos de fosfato de cálcio são destinados a minimizar a resposta imune ao implante (por exemplo, restenose em procedimentos de colocação de stent) e podem é usados para armazenar e liberar um agente medicinalmente ativo de uma maneira controlada. Estes revestimentos podem é aplicados a qualquer dispositivo médico implantável e são úteis para um número procedimentos médicos, incluindo (mas não de modo limitativo) angioplastia por balão, em colocação de stent cardiovascular, colocação de stent e cateterização ureteral. Os revestimentos de fosfato de cálcio podem é aplicados a um substrato como um ou mais revestimentos por um processo de deposição sol-gel, um processo de deposição aerossol-gel, um processo de deposição biomimético, um processo de deposição de cimento de fosfato de cálcio, um processo de deposição eletroforético ou um processo de deposição eletroquímico. O revestimento pode conter e eluir uma droga de uma maneira projetada.
BR0314265-5A 2002-09-13 2003-09-12 Dispositivo médico implantável com um revestimento de fosfato de cálcio e processo de revestir um dispositivo médico implantável e um dispositivo implantável de tecido macio com um revestimento de fosfato de cálcio BR0314265A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41030702P 2002-09-13 2002-09-13
PCT/CA2003/001405 WO2004024201A2 (en) 2002-09-13 2003-09-12 Calcium phosphate coated implantable medical devices and processes for making same

Publications (1)

Publication Number Publication Date
BR0314265A true BR0314265A (pt) 2005-07-26

Family

ID=31994107

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0314265-5A BR0314265A (pt) 2002-09-13 2003-09-12 Dispositivo médico implantável com um revestimento de fosfato de cálcio e processo de revestir um dispositivo médico implantável e um dispositivo implantável de tecido macio com um revestimento de fosfato de cálcio

Country Status (7)

Country Link
US (1) US20060134160A1 (pt)
EP (1) EP1551470A2 (pt)
JP (1) JP2006501887A (pt)
AU (1) AU2003266882A1 (pt)
BR (1) BR0314265A (pt)
CA (1) CA2498743A1 (pt)
WO (1) WO2004024201A2 (pt)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080011613A1 (en) * 2004-07-21 2008-01-17 Rizhi Wang Method of electrolytically depositing a pharmaceutical coating onto a conductive osteal implant
FR2876315A1 (fr) * 2004-10-08 2006-04-14 Rhodia Chimie Sa Produit comprenant un support et un revetement comprenant une couche de matiere minerale, son procede de preparation et une utilisation
AT501408B1 (de) 2004-12-07 2011-03-15 Physikalisches Buero Steinmueller Gmbh Biologische oberflächen
US20060199876A1 (en) * 2005-03-04 2006-09-07 The University Of British Columbia Bioceramic composite coatings and process for making same
US20060216327A1 (en) * 2005-03-28 2006-09-28 Bacterin, Inc. Multilayer coating for releasing biologically-active agents and method of making
US8455088B2 (en) 2005-12-23 2013-06-04 Boston Scientific Scimed, Inc. Spun nanofiber, medical devices, and methods
US8007854B2 (en) 2006-01-04 2011-08-30 The University Of Connecticut Ceramic coating and method of preparation thereof
CA2648670A1 (en) * 2006-04-27 2007-11-08 Miv Therapeutics Inc. Electrolyte solution and method for electrolytic co-deposition of thin film calcium phosphate and drug composites
US9155646B2 (en) * 2006-04-27 2015-10-13 Brs Holdings, Llc Composite stent with bioremovable ceramic flakes
US9101505B2 (en) 2006-04-27 2015-08-11 Brs Holdings, Llc Composite stent
CA2651982C (en) * 2006-05-17 2014-07-15 Debiotech S.A. Anisotropic nanoporous coating for medical implants
FR2902014B1 (fr) * 2006-06-09 2011-07-08 Ricol Jean Paul Gilbert Procede de fabrication d'un materiau biocompatible implantable a taux de cristallinite controle et materiau biocompatible implantable obtenu par un tel procede
FR2902013B1 (fr) * 2006-06-09 2009-01-23 Ricol Jean Paul Gilbert Procede de fabrication d'un materiau biocompatible implantable a reseau mixte pseudo-cristallin et materiau susceptible d'etre obtenu par un tel procede
US20100198345A1 (en) * 2006-06-20 2010-08-05 The University Of British Columbia Calcium phosphate coated implantable medical devices, and electrophoretic deposition processes for making same
WO2007147246A1 (en) * 2006-06-21 2007-12-27 The University Of British Columbia Calcium phosphate coated implantable medical devices, and electrochemical deposition processes for making same
US20070299511A1 (en) * 2006-06-27 2007-12-27 Gale David C Thin stent coating
US20080124373A1 (en) * 2006-08-02 2008-05-29 Inframat Corporation Lumen - supporting devices and methods of making and using
WO2008025122A1 (en) * 2006-08-30 2008-03-06 The University Of British Columbia Bioceramic composite coatings and process for making same
WO2008030174A2 (en) * 2006-09-05 2008-03-13 Doxa Ab Implant coatings having improved haemocompatibility
US20080181928A1 (en) * 2006-12-22 2008-07-31 Miv Therapeutics, Inc. Coatings for implantable medical devices for liposome delivery
RU2447901C2 (ru) 2007-01-21 2012-04-20 Хемотек Аг Медицинский продукт для лечения обтураций просветов организма и для предупреждения угрожающих повторных обтураций
GB0702577D0 (en) * 2007-02-09 2007-03-21 Ucl Business Plc An article and a method of surface treatment of an article
US20080268018A1 (en) * 2007-04-30 2008-10-30 Pacetti Stephen D Method for forming crystallized therapeutic agents on a medical device
US9192697B2 (en) 2007-07-03 2015-11-24 Hemoteq Ag Balloon catheter for treating stenosis of body passages and for preventing threatening restenosis
US20090099651A1 (en) * 2007-10-10 2009-04-16 Miv Therapeutics, Inc. Lipid coatings for implantable medical devices
CA2702209A1 (en) * 2007-10-10 2009-04-16 Miv Therapeutics Inc. Calcium phosphate coated stents comprising cobalt chromium alloy
US9149563B2 (en) 2007-11-06 2015-10-06 The University Of Connecticut Calcium phosphate/structural protein composites and method of preparation thereof
EP2211763A4 (en) * 2007-11-06 2013-02-13 Univ Connecticut CERAMIC / STRUCTURE PROTEIN COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
JP2009201639A (ja) * 2008-02-27 2009-09-10 Univ Kinki インプラント
KR100992891B1 (ko) * 2008-03-28 2010-11-09 한국기계연구원 약물 함유 생체 활성 세라믹 복합 코팅층 및 이의 제조방법
US9114125B2 (en) * 2008-04-11 2015-08-25 Celonova Biosciences, Inc. Drug eluting expandable devices
WO2009132411A1 (en) * 2008-04-28 2009-11-05 The University Of British Columbia Polymer-free drug delivery system for implantable medical devices
US8632843B2 (en) * 2008-11-24 2014-01-21 Promimic Ab Methods and systems of controlled coating of nanoparticles onto micro-rough implant surfaces and associated implants
DE102009001895A1 (de) * 2009-03-26 2010-09-30 Biotronik Vi Patent Ag Medizinisches Implantat zur Medikamentenfreisetzung mit poröser Oberfläche
US8556957B2 (en) 2009-06-18 2013-10-15 Medtronic Vascular, Inc. Biodegradable medical device with hydroxyapatite filaments and biodegradable polymer fibers
US10369256B2 (en) 2009-07-10 2019-08-06 Boston Scientific Scimed, Inc. Use of nanocrystals for drug delivery from a balloon
JP5933434B2 (ja) 2009-07-17 2016-06-08 ボストン サイエンティフィック サイムド,インコーポレイテッドBoston Scientific Scimed,Inc. 薬剤送達バルーンの製造方法
US9399086B2 (en) 2009-07-24 2016-07-26 Warsaw Orthopedic, Inc Implantable medical devices
DE102010025533B4 (de) 2010-06-29 2014-09-04 Heraeus Medical Gmbh Verfahren zur knochenwachstumsfördernden Beschichtung
EP2611476B1 (en) 2010-09-02 2016-08-10 Boston Scientific Scimed, Inc. Coating process for drug delivery balloons using heat-induced rewrap memory
IT1402560B1 (it) * 2010-11-09 2013-09-13 Chemical Ct S R L Elettrodeposizione di idrossiapatite nanometrica su impianti protesici e processo elettrolitico per la sua realizzazione
DE102010055561B4 (de) 2010-12-23 2015-12-31 Heraeus Medical Gmbh Beschichtungsverfahren und Beschichtungsvorrichtung
WO2013022458A1 (en) 2011-08-05 2013-02-14 Boston Scientific Scimed, Inc. Methods of converting amorphous drug substance into crystalline form
US9056152B2 (en) 2011-08-25 2015-06-16 Boston Scientific Scimed, Inc. Medical device with crystalline drug coating
WO2013123018A1 (en) 2012-02-13 2013-08-22 Cook Medical Technologies Llc Medical devices for collecting pathogenic cells
WO2013142763A1 (en) 2012-03-22 2013-09-26 University Of Connecticut Biomimetic scaffold for bone regeneration
ES2717678T3 (es) 2013-04-22 2019-06-24 Stryker European Holdings I Llc Procedimiento para la carga de fármacos sobre superficies de implantes recubiertos de hidroxiapatita
US9919077B2 (en) 2013-06-21 2018-03-20 Stryker European Holdings I, Llc Co-precipitation of a therapeutic agent into hydroxyapatite coatings
US10433889B2 (en) 2013-07-11 2019-10-08 Stryker European Holdings I, Llc Fixation assembly with a flexible elongated member for securing parts of a sternum
CN103405809B (zh) * 2013-07-23 2015-01-21 东华大学 一种利用电沉积技术制备微载体/聚合物复合支架的方法
WO2015028100A1 (en) 2013-09-02 2015-03-05 Stryker Trauma Gmbh Method of manufacturing an implant for use in a surgical procedure
US9562000B2 (en) * 2014-02-14 2017-02-07 Prc-Desoto International, Inc. Amino alcohol treatment for sol-gel conversion coatings, substrates including the same, and methods of making the substrates
EP3200858A4 (en) * 2014-09-30 2018-06-13 The Spectranetics Corporation Electrodeposition coating for medical devices
CN104491934A (zh) * 2014-12-25 2015-04-08 东莞颠覆产品设计有限公司 一种具有胶原蛋白覆膜的可扩张心血管支架
EP3042622B1 (en) 2015-01-09 2018-05-09 Stryker European Holdings I, LLC Implant for bone fixation
US10806827B2 (en) 2015-06-01 2020-10-20 Colorado School Of Mines Controlled and tunable precipitation of biomimetic apatites via in situ mineralization of an organic polymeric matrix
US10926000B2 (en) 2016-05-13 2021-02-23 Colorado School Of Mines Deposition-conversion method for tunable calcium phosphate coatings on substrates and apparatus prepared thereof
EP3320868B1 (en) 2016-11-11 2019-05-01 Stryker European Holdings I, LLC Implant for bone fixation
US10596757B2 (en) 2016-12-06 2020-03-24 Northeastern University Three dimensional mineralization printer
EP3600463B1 (en) * 2017-03-23 2022-03-02 Council of Scientific and Industrial Research A process for coating a biomedical implant with a biocompatible polymer and a biomedical implant therefrom
US10537658B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same
US10537661B2 (en) 2017-03-28 2020-01-21 DePuy Synthes Products, Inc. Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same
CN108760966A (zh) * 2018-05-29 2018-11-06 四川维思达医疗器械有限公司 一种确定磷酸钙电化学涂层中电解液条件的方法
US20210338897A1 (en) * 2018-08-24 2021-11-04 Qvanteq Ag Vascular device and method for manufacturing a vascular device
JP7340798B2 (ja) * 2019-06-13 2023-09-08 国立研究開発法人物質・材料研究機構 積層体の製造方法、及び積層体
CN112587732A (zh) * 2020-11-03 2021-04-02 深圳市迈捷生命科学有限公司 一种纳米羟基磷灰石与磺化聚醚醚酮复合材料的制备方法

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH021286A (ja) * 1988-03-04 1990-01-05 Dentaru Kagaku Kk 生体材料
US5055307A (en) 1988-12-29 1991-10-08 Asahi Kagaku Kogyo Kabushiki Kaisha Slow release drug delivery granules and process for production thereof
US5205921A (en) * 1991-02-04 1993-04-27 Queen's University At Kingston Method for depositing bioactive coatings on conductive substrates
US5258044A (en) 1992-01-30 1993-11-02 Etex Corporation Electrophoretic deposition of calcium phosphate material on implants
JPH06285151A (ja) * 1993-04-01 1994-10-11 Nippon Sherwood Kk 非晶質リン酸カルシウムをコートした医療用具
GB9310194D0 (en) * 1993-05-18 1993-06-30 Millenium Bioligix Inc Assessment of osteoclast activity
DE4431862C2 (de) * 1994-09-07 1997-12-11 Dot Duennschicht Und Oberflaec Verfahren zur Beschichtung von Metall- und Keramikoberflächen mit Hydroxylapatit
JP3600676B2 (ja) * 1996-01-29 2004-12-15 ペンタックス株式会社 生体内可溶性複合体粒子
JPH1072666A (ja) * 1996-08-30 1998-03-17 Japan Steel Works Ltd:The アパタイト薄膜の成膜方法
JPH10102288A (ja) * 1996-09-24 1998-04-21 Queen Mary & Westfield College リン酸カルシウム化合物のコーティング方法
US6972130B1 (en) 1996-10-16 2005-12-06 Etex Corporation Bioceramic compositions
US6387121B1 (en) 1996-10-21 2002-05-14 Inflow Dynamics Inc. Vascular and endoluminal stents with improved coatings
CA2285430C (en) 1997-04-01 2008-11-18 Cap Biotechnology, Inc. Calcium phosphate microcarriers and microspheres
US6273913B1 (en) 1997-04-18 2001-08-14 Cordis Corporation Modified stent useful for delivery of drugs along stent strut
JPH10328292A (ja) * 1997-05-28 1998-12-15 Japan Steel Works Ltd:The 生体材料および生体材料の製造方法
US5899935A (en) * 1997-08-04 1999-05-04 Schneider (Usa) Inc. Balloon expandable braided stent with restraint
WO1999011202A1 (en) * 1997-09-05 1999-03-11 Icet, Inc. Biomimetic calcium phosphate implant coatings and methods for making the same
SE513556C2 (sv) * 1997-11-11 2000-10-02 Nobel Biocare Ab Implantatelement med tunt ytskickt applicerat genom het isostatisk pressning
US5958430A (en) 1998-02-20 1999-09-28 Battelle Memorial Institute Thin film composition with biological substance and method of making
US6139585A (en) * 1998-03-11 2000-10-31 Depuy Orthopaedics, Inc. Bioactive ceramic coating and method
US20010029351A1 (en) * 1998-04-16 2001-10-11 Robert Falotico Drug combinations and delivery devices for the prevention and treatment of vascular disease
US6113993A (en) * 1998-10-28 2000-09-05 Battelle Memorial Institute Method of coating a substrate with a calcium phosphate compound
EP1132058A1 (en) 2000-03-06 2001-09-12 Advanced Laser Applications Holding S.A. Intravascular prothesis
US6629997B2 (en) * 2000-03-27 2003-10-07 Kevin A. Mansmann Meniscus-type implant with hydrogel surface reinforced by three-dimensional mesh
US6426114B1 (en) 2000-05-02 2002-07-30 The University Of British Columbia Sol-gel calcium phosphate ceramic coatings and method of making same
US6663664B1 (en) * 2000-10-26 2003-12-16 Advanced Cardiovascular Systems, Inc. Self-expanding stent with time variable radial force
US6663662B2 (en) * 2000-12-28 2003-12-16 Advanced Cardiovascular Systems, Inc. Diffusion barrier layer for implantable devices
US6730324B2 (en) 2001-04-20 2004-05-04 The University Of British Columbia Biofunctional hydroxyapatite coatings and microspheres for in-situ drug encapsulation
ATE399571T1 (de) * 2001-06-06 2008-07-15 Biomet Merck Gmbh Apatitbeschichteter metallischer werkstoff, verfahren zu dessen herstellung sowie verwendung
CN100515504C (zh) * 2001-10-12 2009-07-22 美国英佛曼公司 涂层,涂布体及其制造方法
JP4181354B2 (ja) * 2002-08-09 2008-11-12 茂樹 本津 医療用機器

Also Published As

Publication number Publication date
US20060134160A1 (en) 2006-06-22
WO2004024201A2 (en) 2004-03-25
JP2006501887A (ja) 2006-01-19
CA2498743A1 (en) 2004-03-25
EP1551470A2 (en) 2005-07-13
WO2004024201A3 (en) 2004-07-15
AU2003266882A1 (en) 2004-04-30

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B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

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B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

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