BR0212036A - Composições farmacêuticas compreendendo conjugados de polissacarìdeos para a inibição da metástase ou prevenção da recorrência de tumor maligno - Google Patents
Composições farmacêuticas compreendendo conjugados de polissacarìdeos para a inibição da metástase ou prevenção da recorrência de tumor malignoInfo
- Publication number
- BR0212036A BR0212036A BR0212036-4A BR0212036A BR0212036A BR 0212036 A BR0212036 A BR 0212036A BR 0212036 A BR0212036 A BR 0212036A BR 0212036 A BR0212036 A BR 0212036A
- Authority
- BR
- Brazil
- Prior art keywords
- malignant tumor
- pharmaceutical compositions
- inhibiting metastasis
- preventing recurrence
- polysaccharide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001249717 | 2001-08-21 | ||
PCT/JP2002/008309 WO2003015826A1 (en) | 2001-08-21 | 2002-08-16 | Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence of maligant tumor |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0212036A true BR0212036A (pt) | 2004-08-17 |
Family
ID=19078678
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR0212036-4A BR0212036A (pt) | 2001-08-21 | 2002-08-16 | Composições farmacêuticas compreendendo conjugados de polissacarìdeos para a inibição da metástase ou prevenção da recorrência de tumor maligno |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1418947A1 (es) |
KR (1) | KR20040027972A (es) |
CN (1) | CN100372570C (es) |
AR (1) | AR035137A1 (es) |
AU (1) | AU2002328093B2 (es) |
BR (1) | BR0212036A (es) |
CA (1) | CA2457056C (es) |
HU (1) | HUP0401351A3 (es) |
IL (1) | IL160148A0 (es) |
MX (1) | MXPA04001599A (es) |
NO (1) | NO20041194L (es) |
NZ (1) | NZ530947A (es) |
PL (1) | PL368319A1 (es) |
RU (1) | RU2275913C2 (es) |
TW (1) | TWI313609B (es) |
UA (1) | UA75450C2 (es) |
WO (1) | WO2003015826A1 (es) |
ZA (1) | ZA200400917B (es) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TW200306314A (en) * | 2002-04-16 | 2003-11-16 | Tanabe Seiyaku Co | Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation |
FR2914305B1 (fr) | 2007-03-29 | 2009-07-03 | Proteins & Peptides Man | Dextran fonctionnalise par des amino-acides hydrophobes. |
KR102140055B1 (ko) | 2008-07-16 | 2020-07-31 | 칠드런'즈 메디컬 센터 코포레이션 | 마이크로채널을 갖는 기관 모방 장치 및 그 사용 및 제조 방법 |
RU2631807C2 (ru) * | 2011-06-02 | 2017-09-26 | Президент Энд Феллоуз Ов Харвард Колледж | Способы и применение систем культуры ткани ex vivo |
PL221351B1 (pl) | 2012-03-14 | 2016-03-31 | Politechnika Warszawska | Sposób otrzymywania nanocząstek polisacharydowych |
KR102052319B1 (ko) | 2012-10-11 | 2019-12-05 | 다이이찌 산쿄 가부시키가이샤 | 항체-약물 콘주게이트 |
EP2910573B1 (en) * | 2012-10-19 | 2020-02-19 | Daiichi Sankyo Company, Limited | Antibody-drug conjugate produced by binding through linker having hydrophilic structure |
CN110464847B (zh) | 2014-01-31 | 2024-02-09 | 第一三共株式会社 | 抗her2抗体-药物偶联物 |
SG11201708242YA (en) | 2015-05-04 | 2017-11-29 | Pfizer | Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof |
CN107922477B (zh) | 2015-06-29 | 2022-11-01 | 第一三共株式会社 | 用于选择性制造抗体-药物缀合物的方法 |
WO2018110515A1 (ja) | 2016-12-12 | 2018-06-21 | 第一三共株式会社 | 抗体-薬物コンジュゲートと免疫チェックポイント阻害剤の組み合わせ |
AU2018210081A1 (en) | 2017-01-17 | 2019-08-08 | Daiichi Sankyo Company, Limited | Anti-GPR20 antibody and anti-GPR20 antibody-drug conjugate |
TWI855528B (zh) | 2017-05-15 | 2024-09-11 | 日商第一三共股份有限公司 | 抗體-藥物結合物之製造方法 |
AU2018327170B2 (en) | 2017-08-31 | 2021-03-11 | Daiichi Sankyo Company, Limited | Novel method for producing antibody-drug conjugate |
CN111051330A (zh) | 2017-08-31 | 2020-04-21 | 第一三共株式会社 | 抗体-药物缀合物的改进制备方法 |
HRP20230787T1 (hr) | 2018-05-18 | 2023-10-27 | Glycotope Gmbh | Anti-muc1 antitijelo |
US12220604B2 (en) | 2018-07-31 | 2025-02-11 | Daiichi Sankyo Company, Limited | Treatment of metastatic brain tumor by administration of an antibody-drug conjugate |
CN109481691A (zh) * | 2018-11-20 | 2019-03-19 | 珠海天香苑生物科技发展股份有限公司 | 吉西他滨-羧甲基多糖共轭物、制备方法及其用途 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5688931A (en) * | 1993-02-26 | 1997-11-18 | Drug Delivery System Institute, Ltd. | Polysaccharide derivatives and drug carriers |
SG50747A1 (en) * | 1995-08-02 | 1998-07-20 | Tanabe Seiyaku Co | Comptothecin derivatives |
CA2192725C (en) * | 1995-12-28 | 2004-04-20 | Kenji Tsujihara | Camptothecin derivatives |
EP0895784B1 (en) * | 1996-04-15 | 2005-11-23 | Asahi Kasei Kabushiki Kaisha | Drug complexes comprising taxane compounds or steroids |
TW527183B (en) * | 1996-06-06 | 2003-04-11 | Daiichi Seiyaku Co | Drug complex |
CN1058038C (zh) * | 1996-12-31 | 2000-11-01 | 中国科学院感光化学研究所 | 低收缩性光固化涂层材料及其制法和用途 |
CN1250293C (zh) * | 1998-05-22 | 2006-04-12 | 第一制药株式会社 | 药物复合物 |
-
2002
- 2002-08-14 TW TW091118260A patent/TWI313609B/zh not_active IP Right Cessation
- 2002-08-15 AR ARP020103077A patent/AR035137A1/es unknown
- 2002-08-16 CN CNB028163176A patent/CN100372570C/zh not_active Expired - Fee Related
- 2002-08-16 HU HU0401351A patent/HUP0401351A3/hu unknown
- 2002-08-16 UA UA2004032071A patent/UA75450C2/uk unknown
- 2002-08-16 PL PL02368319A patent/PL368319A1/xx not_active Application Discontinuation
- 2002-08-16 IL IL16014802A patent/IL160148A0/xx unknown
- 2002-08-16 KR KR10-2004-7002566A patent/KR20040027972A/ko not_active Application Discontinuation
- 2002-08-16 BR BR0212036-4A patent/BR0212036A/pt not_active IP Right Cessation
- 2002-08-16 EP EP02762786A patent/EP1418947A1/en not_active Withdrawn
- 2002-08-16 CA CA002457056A patent/CA2457056C/en not_active Expired - Fee Related
- 2002-08-16 MX MXPA04001599A patent/MXPA04001599A/es unknown
- 2002-08-16 AU AU2002328093A patent/AU2002328093B2/en not_active Ceased
- 2002-08-16 NZ NZ530947A patent/NZ530947A/en not_active IP Right Cessation
- 2002-08-16 WO PCT/JP2002/008309 patent/WO2003015826A1/en active IP Right Grant
- 2002-08-16 RU RU2004108141/15A patent/RU2275913C2/ru not_active IP Right Cessation
-
2004
- 2004-02-04 ZA ZA200400917A patent/ZA200400917B/en unknown
- 2004-03-19 NO NO20041194A patent/NO20041194L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
PL368319A1 (en) | 2005-03-21 |
HUP0401351A2 (hu) | 2004-12-28 |
IL160148A0 (en) | 2004-07-25 |
CN100372570C (zh) | 2008-03-05 |
AU2002328093B2 (en) | 2005-05-05 |
RU2004108141A (ru) | 2005-04-20 |
CA2457056A1 (en) | 2003-02-27 |
MXPA04001599A (es) | 2004-07-08 |
RU2275913C2 (ru) | 2006-05-10 |
AR035137A1 (es) | 2004-04-14 |
EP1418947A1 (en) | 2004-05-19 |
ZA200400917B (en) | 2004-08-25 |
CN1545423A (zh) | 2004-11-10 |
KR20040027972A (ko) | 2004-04-01 |
NZ530947A (en) | 2006-04-28 |
NO20041194L (no) | 2004-03-19 |
HUP0401351A3 (en) | 2011-02-28 |
TWI313609B (en) | 2009-08-21 |
WO2003015826A1 (en) | 2003-02-27 |
UA75450C2 (en) | 2006-04-17 |
CA2457056C (en) | 2008-07-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BR0212036A (pt) | Composições farmacêuticas compreendendo conjugados de polissacarìdeos para a inibição da metástase ou prevenção da recorrência de tumor maligno | |
ATE532790T1 (de) | Einschlussverbindung mit cucurbiturilderivaten als wirtsmolekül, und diese enthaltende pharmazeutische zusammensetzung | |
DE60037020D1 (en) | Anilinochinazoline als protein-tyrosin-kinasehemmer | |
BR9807824A (pt) | Derivados de n-hidróxi-beta-sulfonil-propionamida e seu uso como inibidores de metaloproteinases de matriz | |
NO20042298L (no) | Farmasoytiske preparater og deres anvendelser | |
TR199900049T2 (xx) | Protein tirozin kinaz inhibit�rleri olarak bisiklik heteroaromatik bile�ikler. | |
TR200500745T2 (tr) | Damar gelişimi inhibitörleri olarak kuinazolin türevleri. | |
TR200200717T2 (tr) | Terapötik kinazolin türevleri. | |
BR0115427A (pt) | Composto, composição farmacêutica, métodos para inibir a liberação de peptìdeo beta-amilóide e/ou sua sìntese, para tratar a doença de alzheimer, e para prevenir a doença e o progresso da doença de alzheimer, e, uso de um composto | |
EE200400033A (et) | Vähelahustuvaid ja/või happetundlikke ravimeid janeutraliseeritud happelisi polümeere sisaldavad farmatseutilised kompositsioonid | |
BR0107147A (pt) | Composições farmacêuticas de drogas anti-tuberculosas e processo para as suas preparações | |
WO2003053368A3 (en) | Chalcone derivatives and their use to treat diseases | |
BRPI0203172B8 (pt) | composição farmacêutica para acondroplasia | |
BR0315580A (pt) | Derivados de metileno uréia | |
BRPI0110024B8 (pt) | derivados de ecteinascidina antitumorais, composição farmacêutica que os compreende e uso dos mesmos | |
BRPI0410669A (pt) | inibidores de caspase e usos dos mesmo | |
WO2000045800A3 (en) | Immunosurpressive effects of pteridine derivatives | |
BR0314797A (pt) | Derivados da pirimidineamida e o uso dos mesmos | |
ATE422356T1 (de) | Pharmazeutische zubereitungen | |
ATE249842T1 (de) | Zielgerichte arzneimittel abgabe für zulphonamide-derivate | |
DK1290011T3 (da) | Melphalan-derivater og deres anvendelse som cancer-kemoterapeutiske lægemidler | |
TR199900336T2 (xx) | EAA antagonistleri olarak tetrahidrokinolin t�revleri. | |
BR0008297A (pt) | Uso de 4,6-o-(benzilideno-d1) -d-glucopiranose, 4,6-o-benzilideno-l-glucopiranose, e/ou 4,6-o-(benzilideno-d1) -l-glucopiranose, ou um sal farmacêutico aceitável dos mesmos, derivado de benzaldeìdo composição farmacêutica, e, processo para a fabricação da mesma | |
BR0208017A (pt) | Combinação compreendendo combretastatina e agentes anticâncer | |
WO2001042243A3 (en) | Protein kinase inhibitors |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25D | Requested change of name of applicant approved |
Owner name: MITSUBISHI TANABE PHARMA CORPORATION (JP) Free format text: ALTERADO DE: TANABE SEIYAKU CO., LTD. |
|
B06F | Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette] | ||
B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 9A ANUIDADE(S) |
|
B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2116 DE 26/07/2011. |
|
B15K | Others concerning applications: alteration of classification |
Ipc: A61K 47/61 (2017.01), A61K 47/65 (2017.01), A61P 3 |