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HUP0401351A3 - Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence ofmaligant tumor - Google Patents

Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence ofmaligant tumor

Info

Publication number
HUP0401351A3
HUP0401351A3 HU0401351A HUP0401351A HUP0401351A3 HU P0401351 A3 HUP0401351 A3 HU P0401351A3 HU 0401351 A HU0401351 A HU 0401351A HU P0401351 A HUP0401351 A HU P0401351A HU P0401351 A3 HUP0401351 A3 HU P0401351A3
Authority
HU
Hungary
Prior art keywords
ofmaligant
metastsis
recurrence
tumor
inhibiting
Prior art date
Application number
HU0401351A
Other languages
Hungarian (hu)
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Publication of HUP0401351A2 publication Critical patent/HUP0401351A2/en
Publication of HUP0401351A3 publication Critical patent/HUP0401351A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
HU0401351A 2001-08-21 2002-08-16 Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence ofmaligant tumor HUP0401351A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001249717 2001-08-21
PCT/JP2002/008309 WO2003015826A1 (en) 2001-08-21 2002-08-16 Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence of maligant tumor

Publications (2)

Publication Number Publication Date
HUP0401351A2 HUP0401351A2 (en) 2004-12-28
HUP0401351A3 true HUP0401351A3 (en) 2011-02-28

Family

ID=19078678

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0401351A HUP0401351A3 (en) 2001-08-21 2002-08-16 Pharmaceutical compositions comprising polysaccharide conjugates for inhibiting the metastsis or preventing the recurrence ofmaligant tumor

Country Status (18)

Country Link
EP (1) EP1418947A1 (en)
KR (1) KR20040027972A (en)
CN (1) CN100372570C (en)
AR (1) AR035137A1 (en)
AU (1) AU2002328093B2 (en)
BR (1) BR0212036A (en)
CA (1) CA2457056C (en)
HU (1) HUP0401351A3 (en)
IL (1) IL160148A0 (en)
MX (1) MXPA04001599A (en)
NO (1) NO20041194L (en)
NZ (1) NZ530947A (en)
PL (1) PL368319A1 (en)
RU (1) RU2275913C2 (en)
TW (1) TWI313609B (en)
UA (1) UA75450C2 (en)
WO (1) WO2003015826A1 (en)
ZA (1) ZA200400917B (en)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200306314A (en) * 2002-04-16 2003-11-16 Tanabe Seiyaku Co Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation
RU2283848C1 (en) * 2005-06-16 2006-09-20 Институт нефтехимии и катализа РАН Республика Башкортостан Method for production of alginic acid conjugates
FR2914305B1 (en) * 2007-03-29 2009-07-03 Proteins & Peptides Man DEXTRAN FUNCTIONALIZED BY HYDROPHOBIC AMINO ACIDS
RU2320334C1 (en) * 2006-08-07 2008-03-27 Государственное образовательное учреждение высшего профессионального образования "Нижегородская государственная медицинская академия Федерального Агентства по здравоохранению и социальному развитию" (ГОУ ВПО НижГМА Росздрава) Preparation for inhibiting tumor growth and method for inhibiting tumor growth in experiment
RU2359975C2 (en) * 2007-04-04 2009-06-27 Институт нефтехимии и катализа РАН Method for production of modified arabinogalactan
KR20240093594A (en) 2008-07-16 2024-06-24 칠드런'즈 메디컬 센터 코포레이션 Method of causing mechanical movements within a microfluidic device and microfluidic device
AU2012262139B2 (en) * 2011-06-02 2017-02-23 Children's Medical Center Corporation Methods and uses for ex vivo tissue culture systems
PL221351B1 (en) 2012-03-14 2016-03-31 Politechnika Warszawska Method for obtaining polysaccharide nanoparticles
US10195288B2 (en) 2012-10-11 2019-02-05 Daiichi Sankyo Company, Limited Antibody-drug conjugate
WO2014061277A1 (en) 2012-10-19 2014-04-24 第一三共株式会社 Antibody-drug conjugate produced by binding through linker having hydrophilic structure
EP3973995A1 (en) 2014-01-31 2022-03-30 Daiichi Sankyo Company, Limited Anti-her2 antibody-drug conjugate
NZ736238A (en) 2015-05-04 2022-07-01 Pfizer Group b streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof
ES2938186T3 (en) 2015-06-29 2023-04-05 Daiichi Sankyo Co Ltd Method for the selective manufacture of an antibody-drug conjugate
EP3552626A4 (en) 2016-12-12 2020-06-10 Daiichi Sankyo Company, Limited Combination of antibody-drug conjugate and immune checkpoint inhibitor
BR112019012847A2 (en) 2017-01-17 2019-12-10 Daiichi Sankyo Co Ltd antibody or antibody functional fragment, polynucleotide, expression vector, host cells, method for producing an antibody of interest or antibody functional fragment and for producing an antibody-drug conjugate, antibody-drug conjugate, pharmaceutical composition , antitumor drug; and, method of treating a tumor.
TW202532104A (en) 2017-05-15 2025-08-16 日商第一三共股份有限公司 Antibody-drug conjugates and use thereof
CN117838881A (en) 2017-08-31 2024-04-09 第一三共株式会社 New method for preparing antibody-drug conjugates
JP7366745B2 (en) 2017-08-31 2023-10-23 第一三共株式会社 Improved manufacturing method for antibody-drug conjugates
PT3794042T (en) 2018-05-18 2024-06-14 Daiichi Sankyo Co Ltd Anti-muc1 antibody-drug conjugate
AU2019311596A1 (en) 2018-07-27 2021-01-28 Daiichi Sankyo Company, Limited Protein recognizing drug moiety of antibody-drug conjugate
WO2020027100A1 (en) 2018-07-31 2020-02-06 第一三共株式会社 Treatment of metastatic brain tumor by administration of antibody-drug conjugate
CN109481691A (en) * 2018-11-20 2019-03-19 珠海天香苑生物科技发展股份有限公司 Gemcitabine-carboxymethyl polysaccharide conjugate, preparation method and its usage

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5688931A (en) * 1993-02-26 1997-11-18 Drug Delivery System Institute, Ltd. Polysaccharide derivatives and drug carriers
SG50747A1 (en) * 1995-08-02 1998-07-20 Tanabe Seiyaku Co Comptothecin derivatives
CA2192725C (en) * 1995-12-28 2004-04-20 Kenji Tsujihara Camptothecin derivatives
EP0895784B1 (en) * 1996-04-15 2005-11-23 Asahi Kasei Kabushiki Kaisha Drug complexes comprising taxane compounds or steroids
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
CN1058038C (en) * 1996-12-31 2000-11-01 中国科学院感光化学研究所 Low contract photo-solidification cladding material, its prepn. method and use
US6835807B1 (en) * 1998-05-22 2004-12-28 Daiichi Pharmaceuticals Co., Ltd. Drug complex and drug delivery system

Also Published As

Publication number Publication date
RU2004108141A (en) 2005-04-20
ZA200400917B (en) 2004-08-25
BR0212036A (en) 2004-08-17
NZ530947A (en) 2006-04-28
CN1545423A (en) 2004-11-10
MXPA04001599A (en) 2004-07-08
AU2002328093B2 (en) 2005-05-05
CA2457056A1 (en) 2003-02-27
AR035137A1 (en) 2004-04-14
TWI313609B (en) 2009-08-21
EP1418947A1 (en) 2004-05-19
HUP0401351A2 (en) 2004-12-28
CA2457056C (en) 2008-07-22
WO2003015826A1 (en) 2003-02-27
NO20041194L (en) 2004-03-19
RU2275913C2 (en) 2006-05-10
UA75450C2 (en) 2006-04-17
KR20040027972A (en) 2004-04-01
CN100372570C (en) 2008-03-05
PL368319A1 (en) 2005-03-21
IL160148A0 (en) 2004-07-25

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: MITSUBISHI TANABE PHARMA CORPORATION, JP

Free format text: FORMER OWNER(S): TANABE SEIYAKU CO., LTD., JP

FD9A Lapse of provisional protection due to non-payment of fees