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BR0205990A - Um sistema implantável de liberação unidirecional de agentes terapêuticos para tecidos - Google Patents

Um sistema implantável de liberação unidirecional de agentes terapêuticos para tecidos

Info

Publication number
BR0205990A
BR0205990A BR0205990-8A BR0205990A BR0205990A BR 0205990 A BR0205990 A BR 0205990A BR 0205990 A BR0205990 A BR 0205990A BR 0205990 A BR0205990 A BR 0205990A
Authority
BR
Brazil
Prior art keywords
tissue
implantable
delivery system
organ
agents
Prior art date
Application number
BR0205990-8A
Other languages
English (en)
Inventor
Ricardo Azevedo Ponte Carvalho
A Linn Murphree
Edward E Schmitt
Original Assignee
Ricardo Azevedo Ponte Carvalho
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ricardo Azevedo Ponte Carvalho filed Critical Ricardo Azevedo Ponte Carvalho
Publication of BR0205990A publication Critical patent/BR0205990A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0048Eye, e.g. artificial tears
    • A61K9/0051Ocular inserts, ocular implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067Means for introducing or releasing pharmaceutical products into the body
    • A61F2250/0068Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

"UM SISTEMA IMPLANTáVEL DE LIBERAçãO UNIDIRECIONAL DE AGENTES TERAPêUTICOS PARA TECIDO". Um dispositivo selável de liberação de drogas, cirurgicamente implantável, que uma vez expondo o seu conteúdo, aúavés de uma janela ou porto de interface, à superfície de órgão ou tecido, permite a difusão seletiva, controlada, e unidirecional do agente para um tecido ou órgão. O dispositivo protege órgãos, tecido, ou estruturas adjacentes de níveis altos e desnecessários do agente liberado. Métodos inovadores de liberação de quimioterapêuticos ou agentes bioativos a órgão ou tecidos de mamíferos através de um dispositivo cirurgicamente implantável por meio de um mecanismo protegido e seletivo de difusão, são descritos, assim como os métodos para se conseguir as propriedades selantes do dispositivo.
BR0205990-8A 2001-08-29 2002-08-28 Um sistema implantável de liberação unidirecional de agentes terapêuticos para tecidos BR0205990A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US31595201P 2001-08-29 2001-08-29
PCT/US2002/027434 WO2003020172A1 (en) 2001-08-29 2002-08-28 An implantable and sealable system for unidirectional delivery of therapeutic agents to targeted tissues

Publications (1)

Publication Number Publication Date
BR0205990A true BR0205990A (pt) 2004-01-13

Family

ID=23226807

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0205990-8A BR0205990A (pt) 2001-08-29 2002-08-28 Um sistema implantável de liberação unidirecional de agentes terapêuticos para tecidos

Country Status (12)

Country Link
US (1) US7195774B2 (pt)
EP (1) EP1420716B1 (pt)
JP (2) JP2005501602A (pt)
CN (1) CN1578647B (pt)
AU (1) AU2002324811B2 (pt)
BR (1) BR0205990A (pt)
CA (1) CA2456025C (pt)
ES (1) ES2393101T3 (pt)
PT (1) PT1420716E (pt)
RU (1) RU2311892C2 (pt)
WO (1) WO2003020172A1 (pt)
ZA (1) ZA200304159B (pt)

Families Citing this family (183)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1154691A4 (en) * 1999-01-05 2004-07-07 Massachusetts Eye & Ear Infirm TARGETED ADMINISTRATION OF REGULATED RELEASE MEDICINE TO RETINA AND CHOROID THROUGH SCLEROTIC
US7943162B2 (en) * 1999-10-21 2011-05-17 Alcon, Inc. Drug delivery device
FR2822049B1 (fr) * 2001-03-13 2003-08-01 Dbv Medica 1 Patch destine notamment a depister l'etat de sensibilisation d'un sujet a un allergene, procede de fabrication et utilisation
US7635488B2 (en) * 2001-03-13 2009-12-22 Dbv Technologies Patches and uses thereof
US7431710B2 (en) 2002-04-08 2008-10-07 Glaukos Corporation Ocular implants with anchors and methods thereof
EP1387671A1 (en) 2001-05-03 2004-02-11 MASSACHUSETTS EYE & EAR INFIRMARY Implantable drug delivery device and use thereof
EP2316394B1 (en) 2001-06-12 2016-11-23 The Johns Hopkins University Reservoir device for intraocular drug delivery
US7749528B2 (en) 2001-08-29 2010-07-06 Ricardo Azevedo Pontes De Carvalho Implantable and sealable medical device for unidirectional delivery of therapeutic agents to tissues
JP2005501602A (ja) 2001-08-29 2005-01-20 カルバーリョ、リカルド エイ.ピー. デ 治療薬を組織に一方向送達するための封鎖可能な移殖型装置
MXPA04008903A (es) 2002-03-11 2004-11-26 Alcon Inc Sistema de suministro de farmaco implantable.
AU2003217531A1 (en) * 2002-05-02 2003-11-17 Massachusetts Eye And Ear Infirmary Ocular drug delivery systems and use thereof
AU2003279055A1 (en) * 2002-09-29 2004-04-19 Surmodics, Inc. Methods for treatment and/or prevention of retinal disease
WO2004073551A2 (en) * 2003-02-18 2004-09-02 Massachusetts Eye And Ear Infirmary Transscleral drug delivery device and related methods
US20040225250A1 (en) 2003-05-05 2004-11-11 Michael Yablonski Internal shunt and method for treating glaucoma
US8715243B2 (en) * 2003-06-16 2014-05-06 Ethicon Endo-Surgery, Inc. Injection port applier with downward force actuation
US7561916B2 (en) 2005-06-24 2009-07-14 Ethicon Endo-Surgery, Inc. Implantable medical device with indicator
US7862546B2 (en) * 2003-06-16 2011-01-04 Ethicon Endo-Surgery, Inc. Subcutaneous self attaching injection port with integral moveable retention members
US8007474B2 (en) * 2003-06-16 2011-08-30 Ethicon Endo-Surgery, Inc. Implantable medical device with reversible attachment mechanism and method
CA2536454C (en) 2003-08-26 2013-03-26 Vista Scientific Ocular drug delivery device
US7897384B2 (en) * 2003-09-08 2011-03-01 Ethicon, Inc. Chondrocyte therapeutic delivery system
US7927599B2 (en) * 2003-09-08 2011-04-19 Ethicon, Inc. Chondrocyte therapeutic delivery system
US8257963B2 (en) * 2007-06-01 2012-09-04 Depuy Mitek, Inc. Chondrocyte container and method of use
ATE513571T1 (de) * 2003-09-15 2011-07-15 Allergan Inc Implantierbares vorrichtungsbefestigungssystem
US7291125B2 (en) * 2003-11-14 2007-11-06 Transcend Medical, Inc. Ocular pressure regulation
US8162897B2 (en) * 2003-12-19 2012-04-24 Ethicon Endo-Surgery, Inc. Audible and tactile feedback
US20050137538A1 (en) * 2003-12-22 2005-06-23 Bausch & Lomb Incorporated Drug delivery device
MXPA06003001A (es) * 2004-01-23 2006-06-23 Inamed Medical Products Corp Sistema de fijacion de dispositivo implantable y metodos de uso del mismo.
US9498457B2 (en) 2004-04-30 2016-11-22 Allergan, Inc. Hypotensive prostamide-containing biodegradable intraocular implants and related implants
US7799336B2 (en) 2004-04-30 2010-09-21 Allergan, Inc. Hypotensive lipid-containing biodegradable intraocular implants and related methods
US7993634B2 (en) 2004-04-30 2011-08-09 Allergan, Inc. Oil-in-oil emulsified polymeric implants containing a hypotensive lipid and related methods
US8722097B2 (en) 2004-04-30 2014-05-13 Allergan, Inc. Oil-in-water method for making polymeric implants containing a hypotensive lipid
US20050245905A1 (en) * 2004-04-30 2005-11-03 Schmidt Steven P Local drug-delivery system
WO2006002366A2 (en) * 2004-06-24 2006-01-05 Surmodics, Inc. Biodegradable ocular devices, methods and systems
CA2572592C (en) * 2004-07-02 2015-09-08 Eliot Lazar Treatment medium delivery device and methods for delivery of such treatment mediums to the eye using such a delivery device
US20060110428A1 (en) 2004-07-02 2006-05-25 Eugene Dejuan Methods and devices for the treatment of ocular conditions
US20060067980A1 (en) * 2004-09-30 2006-03-30 Bausch & Lomb Incorporated Capsule for encasing tablets for surgical insertion into the human body
US20060163111A1 (en) * 2004-12-23 2006-07-27 Baril Daniel J Device holder apparatus
EP1868661A1 (en) * 2005-04-08 2007-12-26 SurModics, Inc. Sustained release implants for subretinal delivery
US7918844B2 (en) 2005-06-24 2011-04-05 Ethicon Endo-Surgery, Inc. Applier for implantable medical device
US7651483B2 (en) * 2005-06-24 2010-01-26 Ethicon Endo-Surgery, Inc. Injection port
US20070212397A1 (en) * 2005-09-15 2007-09-13 Roth Daniel B Pharmaceutical delivery device and method for providing ocular treatment
WO2007052730A1 (ja) * 2005-10-31 2007-05-10 Nagasaki University 硝子体内注射用固定具
JP2009513290A (ja) * 2005-10-31 2009-04-02 生立生物科技股▲分▼有限公司 強膜バックリングバンドとその製造方法
JP5180834B2 (ja) 2005-11-29 2013-04-10 スミスクライン ビーチャム コーポレーション 治療方法
EP1979023B1 (en) 2006-01-17 2015-07-22 Transcend Medical, Inc. Glaucoma treatment device
US9084662B2 (en) * 2006-01-17 2015-07-21 Transcend Medical, Inc. Drug delivery treatment device
DE602007012417D1 (de) * 2006-03-14 2011-03-24 Univ Southern California Mems-Vorrichtung zur Wirkstofffreisetzung
US8216603B2 (en) * 2006-05-04 2012-07-10 Herbert Edward Kaufman Method, device, and system for delivery of therapeutic agents to the eye
US20080286337A1 (en) * 2007-05-15 2008-11-20 Boston Foundation For Sight Method of treating a disease in an eye using a scleral lens
US20080287915A1 (en) * 2007-05-15 2008-11-20 Boston Foundation For Sight Tissue engineering system with scleral lens
US20080286338A1 (en) * 2007-05-15 2008-11-20 Boston Foundation For Sight Drug delivery system with scleral lens
JP5328788B2 (ja) * 2007-07-17 2013-10-30 トランセンド・メディカル・インコーポレイテッド ヒドロゲルの拡張能力を備えた眼内植込み体
DE102007044116A1 (de) * 2007-09-16 2009-04-02 Leica Biosystems Nussloch Gmbh Gewebeinfiltrationsvorrichtung
US8480638B2 (en) * 2007-10-04 2013-07-09 Aciont, Inc. Intraocular iontophoretic device and associated methods
WO2009052187A2 (en) * 2007-10-15 2009-04-23 Stokes John P Convergent well irradiating plaque for choroidal melanoma
WO2009064497A1 (en) * 2007-11-15 2009-05-22 The University Of North Carolina At Chapel Hill Prostatic acid phosphatase for the treatment of pain
FR2924349B1 (fr) 2007-12-03 2010-01-01 Dbv Tech Methode de desensibilitation aux allergenes
FR2924350B1 (fr) * 2007-12-03 2010-08-13 Dbv Tech Procede et compositions pour la vaccination par voie cutanee
JP5542691B2 (ja) * 2007-12-20 2014-07-09 ユニバーシティ オブ サザン カリフォルニア 治療薬を送達するための装置および方法
JP2011509120A (ja) 2008-01-03 2011-03-24 ユニバーシティ オブ サザン カリフォルニア 埋め込み可能な薬物送達デバイス、及び当該デバイスを補充するための装置および方法
FR2926466B1 (fr) * 2008-01-23 2010-11-12 Dbv Tech Procede de fabrication de patchs par electrospray
GB2494723B (en) * 2008-03-07 2013-05-08 Milwaukee Electric Tool Corp Visual inspection device
US9023063B2 (en) 2008-04-17 2015-05-05 Apollo Endosurgery, Inc. Implantable access port device having a safety cap
BRPI0910460A2 (pt) * 2008-04-17 2018-02-14 Allergan Inc dispositivo de porta de acesso implantável e sistema de fixação
CN103394142B (zh) 2008-05-08 2015-08-19 迷你泵有限责任公司 可植入药物传送装置与用于填充该装置的设备和方法
EP2323716B1 (en) 2008-05-08 2015-03-04 MiniPumps, LLC Drug-delivery pumps
JP5719767B2 (ja) * 2008-05-08 2015-05-20 ミニパンプス, エルエルシー 埋込型ポンプおよびそのためのカニューレ
US9333297B2 (en) 2008-05-08 2016-05-10 Minipumps, Llc Drug-delivery pump with intelligent control
US9877973B2 (en) 2008-05-12 2018-01-30 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
CA2723588A1 (en) 2008-05-12 2009-11-19 University Of Utah Research Foundation Intraocular drug delivery device and associated uses
US9095404B2 (en) 2008-05-12 2015-08-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10588855B2 (en) 2008-05-12 2020-03-17 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US10064819B2 (en) 2008-05-12 2018-09-04 University Of Utah Research Foundation Intraocular drug delivery device and associated methods
US8562586B2 (en) * 2008-08-26 2013-10-22 Massachusetts Institute Of Technology Devices and systems for local delivery of inotropic agents to the epicardium
US8968210B2 (en) 2008-10-01 2015-03-03 Covidien LLP Device for needle biopsy with integrated needle protection
US9186128B2 (en) 2008-10-01 2015-11-17 Covidien Lp Needle biopsy device
US11298113B2 (en) 2008-10-01 2022-04-12 Covidien Lp Device for needle biopsy with integrated needle protection
US9782565B2 (en) 2008-10-01 2017-10-10 Covidien Lp Endoscopic ultrasound-guided biliary access system
US9332973B2 (en) 2008-10-01 2016-05-10 Covidien Lp Needle biopsy device with exchangeable needle and integrated needle protection
CA2743871C (en) 2008-11-14 2016-10-11 Histogen, Inc. Extracellular matrix compositions for the treatment of cancer
WO2010088258A2 (en) * 2009-01-28 2010-08-05 Transcend Medical, Inc. Ocular implant with stiffness qualities, methods of implantation and system
US8399006B2 (en) 2009-01-29 2013-03-19 Forsight Vision4, Inc. Posterior segment drug delivery
US8623395B2 (en) 2010-01-29 2014-01-07 Forsight Vision4, Inc. Implantable therapeutic device
US10206813B2 (en) 2009-05-18 2019-02-19 Dose Medical Corporation Implants with controlled drug delivery features and methods of using same
EP3412260B1 (en) 2009-05-18 2020-08-26 Dose Medical Corporation Drug eluting ocular implant
KR101429881B1 (ko) 2009-06-03 2014-08-13 포사이트 비젼4, 인크. 전안부 약물 전달
JP5758388B2 (ja) 2009-08-18 2015-08-05 ミニパンプス, エルエルシー 適応制御を有する電解質薬物送達ポンプ
US8715158B2 (en) * 2009-08-26 2014-05-06 Apollo Endosurgery, Inc. Implantable bottom exit port
US8506532B2 (en) * 2009-08-26 2013-08-13 Allergan, Inc. System including access port and applicator tool
US8708979B2 (en) 2009-08-26 2014-04-29 Apollo Endosurgery, Inc. Implantable coupling device
WO2011031299A1 (en) * 2009-08-28 2011-03-17 Mount Sinai School Of Medicine Of New York University Intrapericardial injections
US20120232102A1 (en) 2009-09-30 2012-09-13 Chun-Fang Xu Methods Of Administration And Treatment
US20110105990A1 (en) * 2009-11-04 2011-05-05 Silvestrini Thomas A Zonal drug delivery device and method
US8529492B2 (en) 2009-12-23 2013-09-10 Trascend Medical, Inc. Drug delivery devices and methods
US10166142B2 (en) 2010-01-29 2019-01-01 Forsight Vision4, Inc. Small molecule delivery with implantable therapeutic device
US20110196195A1 (en) * 2010-02-05 2011-08-11 Allergan, Inc. Implantable subcutaneous access port
US8882728B2 (en) * 2010-02-10 2014-11-11 Apollo Endosurgery, Inc. Implantable injection port
US20110270021A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Electronically enhanced access port for a fluid filled implant
US20110270025A1 (en) 2010-04-30 2011-11-03 Allergan, Inc. Remotely powered remotely adjustable gastric band system
US8992415B2 (en) 2010-04-30 2015-03-31 Apollo Endosurgery, Inc. Implantable device to protect tubing from puncture
WO2011146483A1 (en) 2010-05-17 2011-11-24 Aerie Pharmaceuticals, Inc. Drug delivery devices for delivery of ocular therapeutic agents
WO2012019176A2 (en) 2010-08-05 2012-02-09 Forsight Vision4 Inc. Implantable therapeutic device
WO2012019139A1 (en) 2010-08-05 2012-02-09 Forsight Vision4, Inc. Combined drug delivery methods and apparatus
AU2011285545B2 (en) 2010-08-05 2014-03-13 Forsight Vision4, Inc. Injector apparatus and method for drug delivery
WO2012021814A2 (en) 2010-08-13 2012-02-16 Wake Forest University Health Sciences Methods for making a tissue engineered muscle repair (temr) construct in vitro for implantation in vivo
US20120041258A1 (en) 2010-08-16 2012-02-16 Allergan, Inc. Implantable access port system
US20120065460A1 (en) 2010-09-14 2012-03-15 Greg Nitka Implantable access port system
US20120083767A1 (en) 2010-10-01 2012-04-05 The Johns Hopkins University Implantable bioreactor for delivery of paracrine factors
CA2818612C (en) 2010-11-19 2020-12-29 Forsight Vision4, Inc. Therapeutic agent formulations for implanted devices
US9919099B2 (en) 2011-03-14 2018-03-20 Minipumps, Llc Implantable drug pumps and refill devices therefor
US9603997B2 (en) 2011-03-14 2017-03-28 Minipumps, Llc Implantable drug pumps and refill devices therefor
US10286146B2 (en) 2011-03-14 2019-05-14 Minipumps, Llc Implantable drug pumps and refill devices therefor
US8821373B2 (en) 2011-05-10 2014-09-02 Apollo Endosurgery, Inc. Directionless (orientation independent) needle injection port
US10245178B1 (en) 2011-06-07 2019-04-02 Glaukos Corporation Anterior chamber drug-eluting ocular implant
EP4249059A3 (en) 2011-06-28 2023-11-29 ForSight Vision4, Inc. An apparatus for collecting a sample of fluid from a reservoir chamber of a therapeutic device for the eye
US8801597B2 (en) 2011-08-25 2014-08-12 Apollo Endosurgery, Inc. Implantable access port with mesh attachment rivets
JP6185470B2 (ja) * 2011-09-09 2017-08-23 エンドールミナル サイエンシーズ プロプライエタリー リミテッド 血管内装置を制御下でシール付けするための手段
US9102105B2 (en) 2011-09-13 2015-08-11 Vista Scientific Llc Method for forming an ocular drug delivery device
CN103917202B (zh) 2011-09-14 2016-06-29 弗赛特影像5股份有限公司 眼插入件装置和方法
US9883968B2 (en) 2011-09-16 2018-02-06 Forsight Vision4, Inc. Fluid exchange apparatus and methods
US9199069B2 (en) 2011-10-20 2015-12-01 Apollo Endosurgery, Inc. Implantable injection port
US8858421B2 (en) 2011-11-15 2014-10-14 Apollo Endosurgery, Inc. Interior needle stick guard stems for tubes
US9089395B2 (en) 2011-11-16 2015-07-28 Appolo Endosurgery, Inc. Pre-loaded septum for use with an access port
IN2014DN06472A (pt) * 2012-01-27 2015-06-12 Ecole Polytech
US10010448B2 (en) 2012-02-03 2018-07-03 Forsight Vision4, Inc. Insertion and removal methods and apparatus for therapeutic devices
US10085633B2 (en) 2012-04-19 2018-10-02 Novartis Ag Direct visualization system for glaucoma treatment
US9241832B2 (en) 2012-04-24 2016-01-26 Transcend Medical, Inc. Delivery system for ocular implant
EP3228286A1 (en) 2012-09-17 2017-10-11 Novartis AG Expanding ocular impant devices
US20140100530A1 (en) 2012-10-05 2014-04-10 Miguel A. Linares Attachable uterine device with integrated and time release medicinal administering component and insertion tool for implanting such a device
HUE046128T2 (hu) 2012-10-26 2020-02-28 Forsight Vision5 Inc Szemészeti rendszer gyógyszer szembe való késleltetett kibocsátására
US9763829B2 (en) 2012-11-14 2017-09-19 Novartis Ag Flow promoting ocular implant
US9968603B2 (en) 2013-03-14 2018-05-15 Forsight Vision4, Inc. Systems for sustained intraocular delivery of low solubility compounds from a port delivery system implant
EP4302736A3 (en) 2013-03-28 2024-04-03 ForSight Vision4, Inc. Ophthalmic implant for delivering therapeutic substances
US9987163B2 (en) 2013-04-16 2018-06-05 Novartis Ag Device for dispensing intraocular substances
WO2014179568A2 (en) 2013-05-02 2014-11-06 Odin Biotech Two-layer ocular implant
JP6655610B2 (ja) 2014-05-29 2020-02-26 グローコス コーポレーション 制御された薬物送達機能を備えるインプラント及びそれを使用する方法
ES2803102T3 (es) 2014-07-15 2021-01-22 Forsight Vision4 Inc Dispositivo de administración de implante ocular
CA2957548A1 (en) 2014-08-08 2016-02-11 Forsight Vision4, Inc. Stable and soluble formulations of receptor tyrosine kinase inhibitors, and methods of preparation thereof
US10912933B2 (en) * 2014-08-19 2021-02-09 The Regents Of The University Of California Implants for localized drug delivery and methods of use thereof
CN114587774B (zh) 2014-11-10 2024-07-19 弗赛特影像4股份有限公司 治疗眼睛的系统
US9615927B2 (en) * 2015-03-31 2017-04-11 Depuy Ireland Unlimited Company Orthopaedic surgical instrument system and method for protecting a femoral stem taper
EP3283004A4 (en) 2015-04-13 2018-12-05 Forsight Vision5, Inc. Ocular insert composition of semi-crystalline or crystalline pharmaceutically active agent
US10010502B2 (en) 2015-05-19 2018-07-03 Amorphex Therapeutics Llc Device that delivers a sustained low-dose of a myopia-suppressing drug, while preserving pupillary function and accommodation
CN106620893B (zh) 2015-07-23 2021-07-30 爱博诺德(北京)医疗科技股份有限公司 用于眼部疾病光治疗的材料
WO2017040853A1 (en) 2015-09-02 2017-03-09 Glaukos Corporation Drug delivery implants with bi-directional delivery capacity
WO2017049248A1 (en) * 2015-09-16 2017-03-23 Orange County Glaucoma, Pc Shunt for vascular flow enhancement
US11564833B2 (en) 2015-09-25 2023-01-31 Glaukos Corporation Punctal implants with controlled drug delivery features and methods of using same
CN113069681B (zh) 2015-11-20 2022-12-23 弗赛特影像4股份有限公司 制造用于缓释药物递送的治疗装置的方法
CN107007891B (zh) * 2016-01-27 2023-09-19 上海交通大学医学院附属第九人民医院 一种密闭的带有组织再生室的组织器官的再生装置
JP6781973B2 (ja) * 2016-01-29 2020-11-11 学校法人東京女子医科大学 腎臓病進行抑制細胞シート組成物、その製造方法、及び、それを用いた腎臓病進行抑制方法
CN105997338B (zh) * 2016-03-09 2019-04-26 泰山医学院 经玻璃体纳米材料给药系统
AU2017246889B2 (en) 2016-04-05 2021-12-16 Forsight Vision4, Inc. Implantable ocular drug delivery devices
AU2017252294B2 (en) 2016-04-20 2021-12-02 Glaukos Corporation Bioresorbable ocular drug delivery device
JP2019530556A (ja) * 2016-09-30 2019-10-24 リンセラ コーポレイション 二重領域眼球用デバイスによる高精度薬物送達
US20180092776A1 (en) * 2016-09-30 2018-04-05 Sara Heikali Method and device for treating and managing diseased ocular tissue
AU2018372806B2 (en) 2017-11-21 2024-05-30 Forsight Vision4, Inc. Fluid exchange apparatus for expandable port delivery system and methods of use
WO2019195860A2 (en) 2018-04-04 2019-10-10 Vdyne, Llc Devices and methods for anchoring transcatheter heart valve
CN108815687B (zh) * 2018-04-27 2020-07-28 河南中医药大学 一种食管癌化疗装置
CN111989068B (zh) 2018-05-24 2024-10-25 塞拉尼斯伊娃高性能聚合物公司 用于持续释放大分子药物化合物的可植入器件
EP3803866A4 (en) 2018-05-24 2022-03-16 Nureva Inc. METHOD, APPARATUS, AND COMPUTER READABLE MATERIALS FOR MANAGING SEMI-CONSTANT (PERSISTENT) SOUND SOURCES IN MICROPHONE CATCH/HOME AREAS
MX2020012458A (es) 2018-05-24 2021-04-28 Celanese Eva Performance Polymers Llc Dispositivo implantable para liberacion sostenida de un compuesto de farmaco macromolecular.
CN108785791B (zh) * 2018-06-08 2020-12-18 谢博宇 能够阻止血栓形成以及阻止继发感染的双腔静脉输液港
US11278437B2 (en) 2018-12-08 2022-03-22 Vdyne, Inc. Compression capable annular frames for side delivery of transcatheter heart valve replacement
US11071627B2 (en) 2018-10-18 2021-07-27 Vdyne, Inc. Orthogonally delivered transcatheter heart valve frame for valve in valve prosthesis
US12186187B2 (en) 2018-09-20 2025-01-07 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US10321995B1 (en) 2018-09-20 2019-06-18 Vdyne, Llc Orthogonally delivered transcatheter heart valve replacement
US11344413B2 (en) 2018-09-20 2022-05-31 Vdyne, Inc. Transcatheter deliverable prosthetic heart valves and methods of delivery
US10595994B1 (en) 2018-09-20 2020-03-24 Vdyne, Llc Side-delivered transcatheter heart valve replacement
US11109969B2 (en) 2018-10-22 2021-09-07 Vdyne, Inc. Guidewire delivery of transcatheter heart valve
US11253359B2 (en) 2018-12-20 2022-02-22 Vdyne, Inc. Proximal tab for side-delivered transcatheter heart valves and methods of delivery
US11185409B2 (en) 2019-01-26 2021-11-30 Vdyne, Inc. Collapsible inner flow control component for side-delivered transcatheter heart valve prosthesis
US11273032B2 (en) 2019-01-26 2022-03-15 Vdyne, Inc. Collapsible inner flow control component for side-deliverable transcatheter heart valve prosthesis
CA3132162A1 (en) 2019-03-05 2020-09-10 Vdyne, Inc. Tricuspid regurgitation control devices for orthogonal transcatheter heart valve prosthesis
US11076956B2 (en) 2019-03-14 2021-08-03 Vdyne, Inc. Proximal, distal, and anterior anchoring tabs for side-delivered transcatheter mitral valve prosthesis
US11173027B2 (en) 2019-03-14 2021-11-16 Vdyne, Inc. Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same
CN109907861B (zh) * 2019-04-22 2021-03-02 清华大学深圳研究生院 一种多功能性角膜植片
WO2020227249A1 (en) 2019-05-04 2020-11-12 Vdyne, Inc. Cinch device and method for deployment of a side-delivered prosthetic heart valve in a native annulus
EP3969070A4 (en) * 2019-05-13 2022-07-06 University of Pittsburgh - of the Commonwealth System of Higher Education POLYMER-BASED IMPLANT FOR RETINAL THERAPY AND METHODS OF MAKING AND USING THE SAME
AU2020334080A1 (en) 2019-08-20 2022-03-24 Vdyne, Inc. Delivery and retrieval devices and methods for side-deliverable transcatheter prosthetic valves
CA3152632A1 (en) 2019-08-26 2021-03-04 Vdyne, Inc. Side-deliverable transcatheter prosthetic valves and methods for delivering and anchoring the same
US11234813B2 (en) 2020-01-17 2022-02-01 Vdyne, Inc. Ventricular stability elements for side-deliverable prosthetic heart valves and methods of delivery
CN113616855A (zh) * 2021-08-05 2021-11-09 苏州大学 一种储药植入体及制备方法
USD1033637S1 (en) 2022-01-24 2024-07-02 Forsight Vision4, Inc. Fluid exchange device

Family Cites Families (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2071223A5 (en) * 1969-12-28 1971-09-17 Rosen Hyman Contact lens - for medicament application
US4144317A (en) * 1975-05-30 1979-03-13 Alza Corporation Device consisting of copolymer having acetoxy groups for delivering drugs
US4309776A (en) * 1980-05-13 1982-01-12 Ramon Berguer Intravascular implantation device and method of using the same
US4768523A (en) * 1981-04-29 1988-09-06 Lifecore Biomedical, Inc. Hydrogel adhesive
US4378016A (en) * 1981-07-15 1983-03-29 Biotek, Inc. Artificial endocrine gland containing hormone-producing cells
US4479796A (en) * 1982-11-15 1984-10-30 Medtronic, Inc. Self-regenerating drug administration device
US5122127A (en) * 1985-05-01 1992-06-16 University Of Utah Apparatus and methods for use in administering medicaments by direct medicament contact to mucosal tissues
US4549529A (en) * 1985-10-11 1985-10-29 White Thomas C Myopia alleviation prosthesis
US4788971A (en) * 1987-07-13 1988-12-06 Hill Top Research, Inc. Patch system for use on the skin
US5182111A (en) * 1987-11-17 1993-01-26 Boston University Research Foundation In vivo delivery of active factors by co-cultured cell implants
US4978338A (en) * 1988-04-21 1990-12-18 Therex Corp. Implantable infusion apparatus
US5292362A (en) * 1990-07-27 1994-03-08 The Trustees Of Columbia University In The City Of New York Tissue bonding and sealing composition and method of using the same
US5411550A (en) * 1991-09-16 1995-05-02 Atrium Medical Corporation Implantable prosthetic device for the delivery of a bioactive material
US5443505A (en) * 1993-11-15 1995-08-22 Oculex Pharmaceuticals, Inc. Biocompatible ocular implants
US5445616A (en) * 1994-04-29 1995-08-29 Medtronic, Inc. Medication delivery device and method of construction
JP3251294B2 (ja) * 1994-11-10 2002-01-28 ユニヴァーシティ オブ ケンタッキー リサーチ ファウンデーション 体内に薬剤を直接送出する、移植・補充可能な放出制御装置
US5725493A (en) * 1994-12-12 1998-03-10 Avery; Robert Logan Intravitreal medicine delivery
US5558630A (en) * 1994-12-30 1996-09-24 Fisher; Bret L. Intrascleral implant and method for the regulation of intraocular pressure
US5773019A (en) * 1995-09-27 1998-06-30 The University Of Kentucky Research Foundation Implantable controlled release device to deliver drugs directly to an internal portion of the body
US5980497A (en) * 1996-03-15 1999-11-09 Yavitz; Edward Q. Membrane shield for eyes
FR2761075B1 (fr) * 1997-03-24 1999-06-11 Seguin Marie Christine Nouveaux composes a base de silicium biologiquement actifs et leurs applications therapeutiques
EP0991404A1 (en) * 1997-06-24 2000-04-12 Schering-Plough Healthcare Products, Inc. Device for delivery of dermatological ingredients
US5902598A (en) 1997-08-28 1999-05-11 Control Delivery Systems, Inc. Sustained release drug delivery devices
US6217895B1 (en) * 1999-03-22 2001-04-17 Control Delivery Systems Method for treating and/or preventing retinal diseases with sustained release corticosteroids
US7008396B1 (en) * 1999-09-03 2006-03-07 Restorvision, Inc. Ophthalmic device and method of manufacture and use
ES2315598T3 (es) * 1999-10-21 2009-04-01 Alcon, Inc. Dispositivo para la administracion de farmacos.
US6416777B1 (en) * 1999-10-21 2002-07-09 Alcon Universal Ltd. Ophthalmic drug delivery device
US6726920B1 (en) * 2000-09-22 2004-04-27 Durect Corporation Implantable drug delivery patch
US7181287B2 (en) * 2001-02-13 2007-02-20 Second Sight Medical Products, Inc. Implantable drug delivery device
EP1387671A1 (en) 2001-05-03 2004-02-11 MASSACHUSETTS EYE & EAR INFIRMARY Implantable drug delivery device and use thereof
ES2278936T3 (es) * 2001-07-23 2007-08-16 Alcon, Inc. Dispositivo de administracion de farmacos oftalmicos.
US8267995B2 (en) * 2001-08-03 2012-09-18 David Castillejos Method and intra sclera implant for treatment of glaucoma and presbyopia
JP2005501602A (ja) 2001-08-29 2005-01-20 カルバーリョ、リカルド エイ.ピー. デ 治療薬を組織に一方向送達するための封鎖可能な移殖型装置

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