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BR0107667A - Composto de linezolida em forma de cristal que e farmaceuticamente útil como agente antibacteriano e método de preparação do mesmo - Google Patents

Composto de linezolida em forma de cristal que e farmaceuticamente útil como agente antibacteriano e método de preparação do mesmo

Info

Publication number
BR0107667A
BR0107667A BR0107667-1A BR0107667A BR0107667A BR 0107667 A BR0107667 A BR 0107667A BR 0107667 A BR0107667 A BR 0107667A BR 0107667 A BR0107667 A BR 0107667A
Authority
BR
Brazil
Prior art keywords
antibacterial agent
preparing
pharmaceutically useful
compound
crystal
Prior art date
Application number
BR0107667-1A
Other languages
English (en)
Inventor
Michael S Bergren
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22658183&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0107667(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of BR0107667A publication Critical patent/BR0107667A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

"COMPOSTO DE LINEZOLIDA EM FORMA DE CRISTAL QUE é FARMACEUTICAMENTE úTIL COMO AGENTE ANTIBACTERIANO E MéTODO DE PREPARAçãO DO MESMO". A invenção é uma nova forma de cristal (Forma II) de um composto conhecido, linezolida que é útil como agente antibacteriano.
BR0107667-1A 2000-02-02 2001-01-29 Composto de linezolida em forma de cristal que e farmaceuticamente útil como agente antibacteriano e método de preparação do mesmo BR0107667A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US17983700P 2000-02-02 2000-02-02
PCT/US2001/000657 WO2001057035A1 (en) 2000-02-02 2001-01-29 Linezolid-crystal form ii

Publications (1)

Publication Number Publication Date
BR0107667A true BR0107667A (pt) 2002-10-08

Family

ID=22658183

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0107667-1A BR0107667A (pt) 2000-02-02 2001-01-29 Composto de linezolida em forma de cristal que e farmaceuticamente útil como agente antibacteriano e método de preparação do mesmo

Country Status (31)

Country Link
EP (1) EP1255754B1 (pt)
JP (1) JP5235256B2 (pt)
KR (3) KR100864745B1 (pt)
CN (1) CN1221547C (pt)
AR (1) AR027261A1 (pt)
AT (1) ATE297920T1 (pt)
AU (1) AU782138B2 (pt)
BR (1) BR0107667A (pt)
CA (1) CA2395603C (pt)
CO (1) CO5261555A1 (pt)
CZ (1) CZ302292B6 (pt)
DE (1) DE60111497T2 (pt)
DK (1) DK1255754T3 (pt)
EA (1) EA004434B1 (pt)
EE (1) EE05197B1 (pt)
ES (1) ES2242728T3 (pt)
HK (1) HK1051196A1 (pt)
HU (1) HUP0301076A3 (pt)
IL (1) IL151010A0 (pt)
MX (1) MXPA02007471A (pt)
MY (1) MY122829A (pt)
NO (2) NO323459B1 (pt)
NZ (1) NZ520541A (pt)
PE (1) PE20011086A1 (pt)
PL (1) PL356433A1 (pt)
PT (1) PT1255754E (pt)
SI (1) SI1255754T1 (pt)
SK (1) SK287025B6 (pt)
TW (1) TWI297687B (pt)
WO (1) WO2001057035A1 (pt)
ZA (1) ZA200205162B (pt)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100490643B1 (ko) * 2002-10-29 2005-05-19 한국과학기술연구원 새로운 메틸리덴 피페리딘일 옥사졸리딘온 유도체 및이들의 제조방법
ES2331001T3 (es) 2003-10-16 2009-12-18 Symed Labs Limited Forma cristalina de linezolid.
DE602004009344T2 (de) 2004-04-19 2008-07-10 Symed Labs Ltd., Hyderabad Neues verfahren zur herstellung von linezolid und verwandten verbindungen
US20060142283A1 (en) * 2004-06-29 2006-06-29 Judith Aronhime Crystalline form IV of linezolid
EP1745028A2 (en) * 2004-06-29 2007-01-24 Teva Pharmaceutical Industries Ltd Solid forms of linezolid and processes for preparation thereof
WO2006091731A2 (en) 2005-02-24 2006-08-31 Teva Pharmaceutical Industries Ltd. Processes for the preparation of linezolid intermediate
US20070112057A1 (en) * 2005-06-22 2007-05-17 Santiago Ini Polymorphic forms of tegaserod maleate
AU2006277017A1 (en) * 2005-07-20 2007-02-15 Teva Pharmaceutical Industries Ltd. Stable pharmaceutical composition comprising linezolid form IV
WO2007102082A1 (en) * 2006-03-09 2007-09-13 Glenmark Pharmaceuticals Limited High oxazolidinone content solid dosage forms
JP5302200B2 (ja) * 2006-10-23 2013-10-02 コンサート ファーマシューティカルズ インコーポレイテッド オキサゾリジノン誘導体および使用方法
WO2011050826A1 (en) 2009-10-28 2011-05-05 Synthon B.V. Process for making crystalline form a of linezolid
CN103025730A (zh) 2010-04-30 2013-04-03 印第安纳大学研究及科技有限公司 制备利奈唑胺的方法
CN103140487A (zh) 2010-08-11 2013-06-05 斯索恩有限公司 制备利奈唑胺的方法
EP2603506A1 (en) 2010-08-11 2013-06-19 Synthon BV Process for making linezolid
CN103402990A (zh) * 2011-02-24 2013-11-20 李药业有限公司 无水利奈唑胺晶型-ii
WO2012119653A1 (en) 2011-03-09 2012-09-13 Synthon Bv Process for making crystalline form a of linezolid
CN102731341A (zh) * 2011-04-13 2012-10-17 上海医药工业研究院 用于制备利奈唑胺的中间体及其制备方法
CN102766106A (zh) * 2011-05-03 2012-11-07 江苏豪森医药集团有限公司 利奈唑胺的新晶型及其制备方法
CN102399200B (zh) * 2011-12-14 2013-12-04 浙江新东港药业股份有限公司 一种利用悬浮结晶法制备利奈唑胺晶型ⅰ的方法
EP2852580A1 (en) 2012-01-24 2015-04-01 Jubilant Life Sciences Ltd. Improved process for the preparation of stable crystalline form-i of linezolid, substantially free of residual solvent
WO2013120496A1 (en) 2012-02-14 2013-08-22 Pharmathen S.A. Process for the preparation of linezolid in crystalline form and salts thereof
CN102643245A (zh) * 2012-04-10 2012-08-22 杭州华东医药集团生物工程研究所有限公司 一种利奈唑胺晶型及其制备方法
WO2014071990A1 (en) 2012-11-09 2014-05-15 Synthon Bv Process for making linezolid
EP3541442B1 (en) 2016-11-16 2022-01-19 Persica Pharmaceuticals Ltd. Antibiotic formulations for lower back pain
US11517574B2 (en) 2017-11-16 2022-12-06 Persica Pharmaceuticals Ltd. Linezolid formulations

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SK283420B6 (sk) * 1992-05-08 2003-07-01 Pharmacia & Upjohn Company Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny
MY115155A (en) * 1993-09-09 2003-04-30 Upjohn Co Substituted oxazine and thiazine oxazolidinone antimicrobials.
US5688792A (en) * 1994-08-16 1997-11-18 Pharmacia & Upjohn Company Substituted oxazine and thiazine oxazolidinone antimicrobials
CA2248143C (en) * 1996-04-11 2008-10-07 Bruce A. Pearlman Process to prepare oxazolidinones
PL199355B1 (pl) * 1997-11-07 2008-09-30 Upjohn Co Drugorzędowy (S)-alkohol i sposób jego wytwarzania oraz sposób wytwarzania (S)-3-karboaminoalkoholu

Also Published As

Publication number Publication date
JP2003522175A (ja) 2003-07-22
TWI297687B (en) 2008-06-11
AU782138B2 (en) 2005-07-07
ES2242728T3 (es) 2005-11-16
MY122829A (en) 2006-05-31
PL356433A1 (en) 2004-06-28
NO20023654D0 (no) 2002-08-01
HK1051196A1 (en) 2003-07-25
KR100864745B1 (ko) 2008-10-22
KR20080044358A (ko) 2008-05-20
PE20011086A1 (es) 2001-10-04
SI1255754T1 (sl) 2005-12-31
NZ520541A (en) 2004-02-27
NO20023654L (no) 2002-08-01
CN1221547C (zh) 2005-10-05
CA2395603A1 (en) 2001-08-09
EP1255754B1 (en) 2005-06-15
EA200200819A1 (ru) 2003-02-27
KR20020072300A (ko) 2002-09-14
EP1255754A1 (en) 2002-11-13
CZ302292B6 (cs) 2011-02-09
DK1255754T3 (da) 2005-08-22
DE60111497D1 (de) 2005-07-21
KR100781815B1 (ko) 2007-12-03
PT1255754E (pt) 2005-11-30
JP5235256B2 (ja) 2013-07-10
AU3275501A (en) 2001-08-14
HUP0301076A2 (hu) 2003-08-28
CN1394207A (zh) 2003-01-29
SK9942002A3 (en) 2002-11-06
CZ20022635A3 (cs) 2002-10-16
SK287025B6 (sk) 2009-10-07
AR027261A1 (es) 2003-03-19
ATE297920T1 (de) 2005-07-15
NO323459B1 (no) 2007-05-14
KR20070087178A (ko) 2007-08-27
EE200200420A (et) 2003-12-15
WO2001057035A1 (en) 2001-08-09
CA2395603C (en) 2010-03-23
EA004434B1 (ru) 2004-04-29
IL151010A0 (en) 2003-02-12
ZA200205162B (en) 2003-09-29
EE05197B1 (et) 2009-08-17
CO5261555A1 (es) 2003-03-31
NO20065836L (no) 2002-08-01
MXPA02007471A (es) 2002-12-13
DE60111497T2 (de) 2006-05-18
HUP0301076A3 (en) 2004-06-28

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Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]

Free format text: DE ACORDO COM ART. 34 " II " DA LPI ( LEI 9279, DE 14/05/96 ) , O EXAME FICA SUSPENSO PARA QUE O REQUERENTE APRESENTE DOCUMENTOS NECESSARIOS A REGULARIZACAO DO PROCESSO E EXAME DO PEDIDO.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.