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BG108486A - Самоемулгиращи се препарати на инхибитори на протеин, пренасящ холестеролестер - Google Patents

Самоемулгиращи се препарати на инхибитори на протеин, пренасящ холестеролестер Download PDF

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Publication number
BG108486A
BG108486A BG108486A BG10848603A BG108486A BG 108486 A BG108486 A BG 108486A BG 108486 A BG108486 A BG 108486A BG 10848603 A BG10848603 A BG 10848603A BG 108486 A BG108486 A BG 108486A
Authority
BG
Bulgaria
Prior art keywords
substituted
optionally
trifluoromethyl
carbon atoms
alkyl
Prior art date
Application number
BG108486A
Other languages
Bulgarian (bg)
English (en)
Inventor
Michael GUMKOWSKI
Sharad Murdande
Michael Perlman
Franco LOMBARDO
Original Assignee
Pfizer Products Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Products Inc. filed Critical Pfizer Products Inc.
Publication of BG108486A publication Critical patent/BG108486A/bg

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Colloid Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Steroid Compounds (AREA)
BG108486A 2001-06-21 2003-12-22 Самоемулгиращи се препарати на инхибитори на протеин, пренасящ холестеролестер BG108486A (bg)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US30002801P 2001-06-21 2001-06-21

Publications (1)

Publication Number Publication Date
BG108486A true BG108486A (bg) 2005-03-31

Family

ID=23157363

Family Applications (1)

Application Number Title Priority Date Filing Date
BG108486A BG108486A (bg) 2001-06-21 2003-12-22 Самоемулгиращи се препарати на инхибитори на протеин, пренасящ холестеролестер

Country Status (33)

Country Link
US (2) US6962931B2 (fr)
EP (1) EP1453544A2 (fr)
JP (1) JP2005500314A (fr)
KR (1) KR20040015746A (fr)
CN (1) CN1635911A (fr)
AP (1) AP2002002559A0 (fr)
AR (1) AR034599A1 (fr)
BG (1) BG108486A (fr)
BR (1) BR0210505A (fr)
CA (1) CA2455288A1 (fr)
CR (1) CR7163A (fr)
CZ (1) CZ20033341A3 (fr)
EA (1) EA200301139A1 (fr)
EC (1) ECSP034875A (fr)
EE (1) EE200400024A (fr)
GT (1) GT200200124A (fr)
HN (1) HN2002000153A (fr)
HU (1) HUP0400263A2 (fr)
IL (1) IL158765A0 (fr)
IS (1) IS7014A (fr)
MA (1) MA27034A1 (fr)
MX (1) MXPA04000014A (fr)
NO (1) NO20035632L (fr)
OA (1) OA12619A (fr)
PA (1) PA8548601A1 (fr)
PE (1) PE20030128A1 (fr)
PL (1) PL368850A1 (fr)
SK (1) SK15172003A3 (fr)
SV (1) SV2003001103A (fr)
TN (1) TNSN03139A1 (fr)
UY (1) UY27344A1 (fr)
WO (1) WO2003000295A2 (fr)
ZA (1) ZA200308561B (fr)

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PA8548601A1 (es) 2003-09-05
ECSP034875A (es) 2004-01-28
IL158765A0 (en) 2004-05-12
OA12619A (en) 2006-06-12
US20030022944A1 (en) 2003-01-30
NO20035632L (no) 2004-02-18
IS7014A (is) 2003-10-31
EE200400024A (et) 2004-06-15
WO2003000295A2 (fr) 2003-01-03
PE20030128A1 (es) 2003-02-28
CN1635911A (zh) 2005-07-06
NO20035632D0 (no) 2003-12-17
ZA200308561B (en) 2004-11-17
SV2003001103A (es) 2003-03-18
CA2455288A1 (fr) 2003-01-03
JP2005500314A (ja) 2005-01-06
BR0210505A (pt) 2004-05-18
AR034599A1 (es) 2004-03-03
CZ20033341A3 (cs) 2004-10-13
US20060014788A1 (en) 2006-01-19
MXPA04000014A (es) 2004-05-21
PL368850A1 (en) 2005-04-04
UY27344A1 (es) 2003-01-31
HN2002000153A (es) 2002-11-05
EP1453544A2 (fr) 2004-09-08
US6962931B2 (en) 2005-11-08
CR7163A (es) 2004-02-23
SK15172003A3 (en) 2004-11-03
MA27034A1 (fr) 2004-12-20
AP2002002559A0 (en) 2002-06-30
EA200301139A1 (ru) 2004-12-30
WO2003000295A3 (fr) 2004-05-27
TNSN03139A1 (fr) 2005-12-23
KR20040015746A (ko) 2004-02-19
GT200200124A (es) 2003-09-22
HUP0400263A2 (hu) 2005-03-29

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