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BE1010962A4 - Nouveaux derives de 2,3-benzodiazepine. - Google Patents

Nouveaux derives de 2,3-benzodiazepine. Download PDF

Info

Publication number
BE1010962A4
BE1010962A4 BE9700308A BE9700308A BE1010962A4 BE 1010962 A4 BE1010962 A4 BE 1010962A4 BE 9700308 A BE9700308 A BE 9700308A BE 9700308 A BE9700308 A BE 9700308A BE 1010962 A4 BE1010962 A4 BE 1010962A4
Authority
BE
Belgium
Prior art keywords
group
hydrogen
formula
methyl
dihydro
Prior art date
Application number
BE9700308A
Other languages
English (en)
French (fr)
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU9600871A external-priority patent/HU9600871D0/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Application granted granted Critical
Publication of BE1010962A4 publication Critical patent/BE1010962A4/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/02—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BE9700308A 1996-04-04 1997-04-03 Nouveaux derives de 2,3-benzodiazepine. BE1010962A4 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9600871A HU9600871D0 (en) 1996-04-04 1996-04-04 New 2,3-benzodiazepine derivatives

Publications (1)

Publication Number Publication Date
BE1010962A4 true BE1010962A4 (fr) 1999-03-02

Family

ID=89993864

Family Applications (1)

Application Number Title Priority Date Filing Date
BE9700308A BE1010962A4 (fr) 1996-04-04 1997-04-03 Nouveaux derives de 2,3-benzodiazepine.

Country Status (11)

Country Link
KR (1) KR970069997A (es)
AT (1) ATE254608T1 (es)
AU (1) AU720745B2 (es)
BE (1) BE1010962A4 (es)
DE (1) DE59711013D1 (es)
ES (1) ES2127699B1 (es)
IT (1) IT1290453B1 (es)
NZ (1) NZ314517A (es)
UA (1) UA45358C2 (es)
YU (1) YU13197A (es)
ZA (1) ZA972746B (es)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322346A (en) * 1978-10-19 1982-03-30 Jeno Korosi 5H-2,3-Benzodiazepine derivatives
EP0492485A1 (en) * 1990-12-21 1992-07-01 Gyogyszerkutato Intezet N-Acyl-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for preparing same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU186760B (en) * 1981-03-12 1985-09-30 Gyogyszerkutato Intezet Process for preparing 3,4-dihydro-5h-2,3-aenzodiazepine derivatives
HU208429B (en) * 1991-05-03 1993-10-28 Gyogyszerkutato Intezet Process for producing 1-/3-chloro-phenyl/-4-methyl-7,8-dimethoxy-5h-2,3-benzodiazepine of high purity
DE69534407T2 (de) * 1994-08-31 2006-03-16 Eli Lilly And Co., Indianapolis Dihydro-2,3-Benzodiazepinderivate

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4322346A (en) * 1978-10-19 1982-03-30 Jeno Korosi 5H-2,3-Benzodiazepine derivatives
EP0492485A1 (en) * 1990-12-21 1992-07-01 Gyogyszerkutato Intezet N-Acyl-2,3-benzodiazepine derivatives, pharmaceutical compositions containing them and process for preparing same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
VIZI E S ET AL: "2,3-Benzodiazepines (GYKI 52466 and analogs): Negative allosteric modulators of AMPA receptors", CNS DRUG REV. (CDREFB,1080563X);96; VOL.2 (1); PP.91-126, HUNGARIAN ACADEMY SCIENCES;INSTITUTE EXPERIMENTAL MEDICINE; BUDAPEST; H-1450; HUNG. (HU), XP002035188 *

Also Published As

Publication number Publication date
IT1290453B1 (it) 1998-12-03
ITMI970776A1 (it) 1998-10-04
YU13197A (sh) 1999-09-27
UA45358C2 (uk) 2002-04-15
ES2127699B1 (es) 2000-01-16
KR970069997A (ko) 1997-11-07
DE59711013D1 (de) 2003-12-24
ZA972746B (en) 1998-10-09
ES2127699A1 (es) 1999-04-16
AU720745B2 (en) 2000-06-08
AU1773497A (en) 1997-10-09
NZ314517A (en) 2000-03-27
ATE254608T1 (de) 2003-12-15

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: EGIS GYOGYSZERGYAR RT

Effective date: 20010430