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AU722147B2 - N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics - Google Patents

N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics Download PDF

Info

Publication number
AU722147B2
AU722147B2 AU44638/97A AU4463897A AU722147B2 AU 722147 B2 AU722147 B2 AU 722147B2 AU 44638/97 A AU44638/97 A AU 44638/97A AU 4463897 A AU4463897 A AU 4463897A AU 722147 B2 AU722147 B2 AU 722147B2
Authority
AU
Australia
Prior art keywords
general formula
compound
disorders
disease
piperidine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU44638/97A
Other languages
English (en)
Other versions
AU4463897A (en
Inventor
Gihad Dargazanli
Jonathan Frost
Pascal George
Patrick Lardenois
Pascale Magat
Maria-Carmen Renones
Johannes Schoemaker
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Publication of AU4463897A publication Critical patent/AU4463897A/en
Application granted granted Critical
Publication of AU722147B2 publication Critical patent/AU722147B2/en
Assigned to SANOFI-SYNTHELABO reassignment SANOFI-SYNTHELABO Amend patent request/document other than specification (104) Assignors: SYNTHELABO
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AU44638/97A 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics Ceased AU722147B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (fr) 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
FR96/11925 1996-10-01
PCT/FR1997/001692 WO1998014444A1 (fr) 1996-10-01 1997-09-26 Derives de n-(benzothiazol-2-yl)piperidine-1-ethanamine, leur preparation et leur application en therapeutique

Publications (2)

Publication Number Publication Date
AU4463897A AU4463897A (en) 1998-04-24
AU722147B2 true AU722147B2 (en) 2000-07-20

Family

ID=9496217

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44638/97A Ceased AU722147B2 (en) 1996-10-01 1997-09-26 N-(benzothiazol-2-yl) piperidine-1-ethanamine derivatives, their preparation and application in therapeutics

Country Status (23)

Country Link
EP (1) EP0929550A1 (bg)
JP (1) JP2001501217A (bg)
KR (1) KR20000048767A (bg)
CN (1) CN1230959A (bg)
AR (1) AR009105A1 (bg)
AU (1) AU722147B2 (bg)
BG (1) BG103271A (bg)
BR (1) BR9711842A (bg)
CA (1) CA2266510A1 (bg)
CO (1) CO4650030A1 (bg)
CZ (1) CZ112699A3 (bg)
EE (1) EE9900135A (bg)
FR (1) FR2753970B1 (bg)
HU (1) HUP9904091A3 (bg)
IL (1) IL128902A (bg)
NO (1) NO991581L (bg)
NZ (1) NZ334553A (bg)
PL (1) PL332648A1 (bg)
SK (1) SK42299A3 (bg)
TR (1) TR199900634T2 (bg)
TW (1) TW438800B (bg)
WO (1) WO1998014444A1 (bg)
ZA (1) ZA978772B (bg)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
CZ2003182A3 (cs) 2000-06-21 2003-06-18 F. Hoffmann-La Roche Ag Deriváty benzothiazolu
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
RU2006117631A (ru) * 2003-10-24 2007-12-10 Ф.Хоффманн-Ля Рош Аг (Ch) Антагонисты рецептора ссr3
PT1753760E (pt) 2004-05-24 2008-02-12 Hoffmann La Roche '' - metoxi - 7 - morfolin - 4 - il - benzotiazol - 2 - il) - amida do ácido 4 - hidroxi - 4 - metil - piperidina - 1 - carboxílico''
JP4633123B2 (ja) 2004-11-05 2011-02-16 エフ．ホフマン−ラ ロシュ アーゲー イソニコチン酸誘導体の製造方法
EP1863818B1 (en) 2005-03-23 2010-03-10 F.Hoffmann-La Roche Ag Acetylenyl-pyrazolo-pvrimidine derivatives as mglur2 antagonists
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법

Also Published As

Publication number Publication date
FR2753970B1 (fr) 1998-10-30
BR9711842A (pt) 1999-08-24
IL128902A (en) 2001-07-24
NO991581L (no) 1999-06-01
BG103271A (bg) 2000-05-31
NZ334553A (en) 2000-11-24
SK42299A3 (en) 1999-12-10
TR199900634T2 (xx) 1999-06-21
NO991581D0 (no) 1999-03-30
EE9900135A (et) 1999-12-15
AU4463897A (en) 1998-04-24
AR009105A1 (es) 2000-03-08
CA2266510A1 (en) 1998-04-09
ZA978772B (en) 1998-03-27
CO4650030A1 (es) 1998-09-03
HUP9904091A2 (hu) 2000-05-28
CN1230959A (zh) 1999-10-06
HUP9904091A3 (en) 2000-07-28
KR20000048767A (ko) 2000-07-25
CZ112699A3 (cs) 1999-06-16
IL128902A0 (en) 2000-02-17
FR2753970A1 (fr) 1998-04-03
JP2001501217A (ja) 2001-01-30
WO1998014444A1 (fr) 1998-04-09
EP0929550A1 (fr) 1999-07-21
TW438800B (en) 2001-06-07
PL332648A1 (en) 1999-09-27

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Legal Events

Date Code Title Description
TC Change of applicant's name (sec. 104)

Owner name: SANOFI-SYNTHELABO

Free format text: FORMER NAME: SYNTHELABO

FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired