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BG103271A - Производни на n-(бензотиазол-2-ил) пиперидин-1-етанамин, метод за тяхното получаване и използванетоим като терапевтични средства - Google Patents

Производни на n-(бензотиазол-2-ил) пиперидин-1-етанамин, метод за тяхното получаване и използванетоим като терапевтични средства

Info

Publication number
BG103271A
BG103271A BG103271A BG10327199A BG103271A BG 103271 A BG103271 A BG 103271A BG 103271 A BG103271 A BG 103271A BG 10327199 A BG10327199 A BG 10327199A BG 103271 A BG103271 A BG 103271A
Authority
BG
Bulgaria
Prior art keywords
ethaneamines
benzothiazol
piperidine
derivatives
preparation
Prior art date
Application number
BG103271A
Other languages
English (en)
Inventor
Gihad Dargazanli
Pascal George
Patrick Lardenois
Jonathan Frost
Johannes Schoemaker
Maria-Carmen Renones
Pascale Magat
Original Assignee
Sanofi-Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi-Synthelabo filed Critical Sanofi-Synthelabo
Publication of BG103271A publication Critical patent/BG103271A/bg

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Изобретението се отнася до съединения с обща формулa, в която n има стойност 0, 1, 2 или 3, R1 означава водород или халоген, или метилова група, или метоксигрупа, R2 е водород или метилова група, R3 означава водород или един или два халогенни атома.
BG103271A 1996-10-01 1999-03-22 Производни на n-(бензотиазол-2-ил) пиперидин-1-етанамин, метод за тяхното получаване и използванетоим като терапевтични средства BG103271A (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (fr) 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique
PCT/FR1997/001692 WO1998014444A1 (fr) 1996-10-01 1997-09-26 Derives de n-(benzothiazol-2-yl)piperidine-1-ethanamine, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
BG103271A true BG103271A (bg) 2000-05-31

Family

ID=9496217

Family Applications (1)

Application Number Title Priority Date Filing Date
BG103271A BG103271A (bg) 1996-10-01 1999-03-22 Производни на n-(бензотиазол-2-ил) пиперидин-1-етанамин, метод за тяхното получаване и използванетоим като терапевтични средства

Country Status (23)

Country Link
EP (1) EP0929550A1 (bg)
JP (1) JP2001501217A (bg)
KR (1) KR20000048767A (bg)
CN (1) CN1230959A (bg)
AR (1) AR009105A1 (bg)
AU (1) AU722147B2 (bg)
BG (1) BG103271A (bg)
BR (1) BR9711842A (bg)
CA (1) CA2266510A1 (bg)
CO (1) CO4650030A1 (bg)
CZ (1) CZ112699A3 (bg)
EE (1) EE9900135A (bg)
FR (1) FR2753970B1 (bg)
HU (1) HUP9904091A3 (bg)
IL (1) IL128902A (bg)
NO (1) NO991581L (bg)
NZ (1) NZ334553A (bg)
PL (1) PL332648A1 (bg)
SK (1) SK42299A3 (bg)
TR (1) TR199900634T2 (bg)
TW (1) TW438800B (bg)
WO (1) WO1998014444A1 (bg)
ZA (1) ZA978772B (bg)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
CZ2003182A3 (cs) 2000-06-21 2003-06-18 F. Hoffmann-La Roche Ag Deriváty benzothiazolu
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
RU2006117631A (ru) * 2003-10-24 2007-12-10 Ф.Хоффманн-Ля Рош Аг (Ch) Антагонисты рецептора ссr3
PT1753760E (pt) 2004-05-24 2008-02-12 Hoffmann La Roche '' - metoxi - 7 - morfolin - 4 - il - benzotiazol - 2 - il) - amida do ácido 4 - hidroxi - 4 - metil - piperidina - 1 - carboxílico''
JP4633123B2 (ja) 2004-11-05 2011-02-16 エフ．ホフマン−ラ ロシュ アーゲー イソニコチン酸誘導体の製造方法
EP1863818B1 (en) 2005-03-23 2010-03-10 F.Hoffmann-La Roche Ag Acetylenyl-pyrazolo-pvrimidine derivatives as mglur2 antagonists
ES2340321T3 (es) 2005-09-27 2010-06-01 F.Hoffmann-La Roche Ag Oxadiazolilpirazolo-pirimidinas, como antagonistas de mglur2.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법

Also Published As

Publication number Publication date
FR2753970B1 (fr) 1998-10-30
BR9711842A (pt) 1999-08-24
IL128902A (en) 2001-07-24
NO991581L (no) 1999-06-01
NZ334553A (en) 2000-11-24
SK42299A3 (en) 1999-12-10
TR199900634T2 (xx) 1999-06-21
NO991581D0 (no) 1999-03-30
EE9900135A (et) 1999-12-15
AU4463897A (en) 1998-04-24
AR009105A1 (es) 2000-03-08
CA2266510A1 (en) 1998-04-09
ZA978772B (en) 1998-03-27
CO4650030A1 (es) 1998-09-03
HUP9904091A2 (hu) 2000-05-28
CN1230959A (zh) 1999-10-06
HUP9904091A3 (en) 2000-07-28
KR20000048767A (ko) 2000-07-25
CZ112699A3 (cs) 1999-06-16
IL128902A0 (en) 2000-02-17
FR2753970A1 (fr) 1998-04-03
JP2001501217A (ja) 2001-01-30
WO1998014444A1 (fr) 1998-04-09
EP0929550A1 (fr) 1999-07-21
AU722147B2 (en) 2000-07-20
TW438800B (en) 2001-06-07
PL332648A1 (en) 1999-09-27

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