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AU2002320124B2 - Compact automated radionuclide separator - Google Patents

Compact automated radionuclide separator Download PDF

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Publication number
AU2002320124B2
AU2002320124B2 AU2002320124A AU2002320124A AU2002320124B2 AU 2002320124 B2 AU2002320124 B2 AU 2002320124B2 AU 2002320124 A AU2002320124 A AU 2002320124A AU 2002320124 A AU2002320124 A AU 2002320124A AU 2002320124 B2 AU2002320124 B2 AU 2002320124B2
Authority
AU
Australia
Prior art keywords
radionuclides
automatically separating
separation
parent
separation column
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
AU2002320124A
Other languages
English (en)
Other versions
AU2002320124A1 (en
Inventor
John J. Hines
John E. Young
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PG Research Foundation Inc
Original Assignee
PG Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by PG Research Foundation Inc filed Critical PG Research Foundation Inc
Publication of AU2002320124A1 publication Critical patent/AU2002320124A1/en
Application granted granted Critical
Publication of AU2002320124B2 publication Critical patent/AU2002320124B2/en
Anticipated expiration legal-status Critical
Expired legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/04—Preparation or injection of sample to be analysed
    • G01N30/06—Preparation
    • G01N30/08—Preparation using an enricher
    • G01N2030/085—Preparation using an enricher using absorbing precolumn
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8804—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 automated systems
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/26—Conditioning of the fluid carrier; Flow patterns
    • G01N30/38—Flow patterns
    • G01N30/46—Flow patterns using more than one column
    • G01N30/468—Flow patterns using more than one column involving switching between different column configurations
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/86—Signal analysis
    • G01N30/8651—Recording, data aquisition, archiving and storage
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/0005—Isotope delivery systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S422/00—Chemical apparatus and process disinfecting, deodorizing, preserving, or sterilizing
    • Y10S422/903—Radioactive material apparatus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Toys (AREA)
  • Circuits Of Receivers In General (AREA)
AU2002320124A 2001-06-22 2002-06-21 Compact automated radionuclide separator Expired AU2002320124B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US30013401P 2001-06-22 2001-06-22
US60/300,134 2001-06-22
PCT/US2002/019609 WO2003000375A1 (fr) 2001-06-22 2002-06-21 Separateur de radionucleides compact et automatique

Publications (2)

Publication Number Publication Date
AU2002320124A1 AU2002320124A1 (en) 2003-06-19
AU2002320124B2 true AU2002320124B2 (en) 2006-12-14

Family

ID=23157852

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2002320124A Expired AU2002320124B2 (en) 2001-06-22 2002-06-21 Compact automated radionuclide separator

Country Status (11)

Country Link
US (1) US6770195B2 (fr)
EP (1) EP1404429B1 (fr)
JP (1) JP4309254B2 (fr)
CN (1) CN1306981C (fr)
AT (1) ATE408818T1 (fr)
AU (1) AU2002320124B2 (fr)
CA (1) CA2451154C (fr)
DE (1) DE60228960D1 (fr)
EA (1) EA005712B1 (fr)
WO (1) WO2003000375A1 (fr)
ZA (1) ZA200309765B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6998052B2 (en) * 2002-04-12 2006-02-14 Pg Research Foundation Multicolumn selectivity inversion generator for production of ultrapure radionuclides
US7087206B2 (en) * 2002-04-12 2006-08-08 Pg Research Foundation Multicolumn selectivity inversion generator for production of high purity actinium for use in therapeutic nuclear medicine
EP1772157A1 (fr) * 2005-10-06 2007-04-11 Karl-Heinz Jansen Assemblage modulaire et synthése pour la production des radiopharmaceutiques et des nucleides
US7402251B2 (en) * 2005-12-28 2008-07-22 Mann Welding Company Chromatography column and method of operation
KR100742639B1 (ko) * 2006-01-19 2007-07-25 한국원자력안전기술원 방사성핵종 분리용 다수 시료 동시자동분리장치 및 그를이용한 우라늄 （ｕ） 자동분리방법
US7554098B2 (en) * 2007-04-20 2009-06-30 Battelle Memorial Institute Medical isotope generator systems
JP5570989B2 (ja) * 2007-08-31 2014-08-13 アムジエン・インコーポレーテツド 固体タンパク質製剤
FR2990956B1 (fr) * 2012-05-24 2014-07-04 Areva Med Sas Procede et appareil pour la production de plomb 212 a usage medical
CA2928838C (fr) * 2013-10-30 2022-05-17 NorthStar Medical Radioisotopes LLC Systeme de traitement et de tracage de radionucleides
CN104268374B (zh) * 2014-09-09 2017-07-28 中国核电工程有限公司 计算长寿命放射性核素的短半衰期子核岸边沉积外照射剂量的方法
US20160223205A1 (en) * 2015-01-30 2016-08-04 Oscar Yonghwan CHOI Timer device for stove
CN106732481B (zh) * 2017-01-10 2019-04-05 苏州大学 一种高锝酸根吸附剂及其合成方法与在处理放射性废水中的应用
EP3773996A4 (fr) 2018-03-26 2022-03-30 Triumf Systèmes, appareil et procédés pour séparer de l'actinium, du radium et du thorium
CN109521457B (zh) * 2018-09-25 2022-10-21 中国辐射防护研究院 一种基于信息准则的γ辐射源项划分方法及系统
CN116594053B (zh) * 2023-07-18 2024-01-19 清华大学 放射性溶液中超铀α核素、90Sr和137Cs的组分离系统及装置

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59145022A (ja) * 1983-02-08 1984-08-20 Japan Atom Energy Res Inst リチウム同位体を分離する方法
US4762617A (en) * 1987-01-15 1988-08-09 The United States Of America As Represented By The United States Department Of Energy Size-exclusion chromatography system for macromolecular interaction analysis
US5110474A (en) * 1990-04-09 1992-05-05 Arch Development Corporation Method for liquid chromatographic extraction of strontium from acid solutions
US5368736A (en) * 1993-07-26 1994-11-29 The United States Of America As Represented By The United States Department Of Energy Process for the separation and purification of yttrium-90 for medical applications
CA2146177C (fr) * 1995-04-03 2000-09-05 Adrian P. Wade Reseau d'analyse de flux intelligent
US5774782A (en) * 1996-05-22 1998-06-30 Lockheed Martin Energy Systems, Inc. Technetium-99m generator system
EP0979513A4 (fr) 1996-08-26 2002-04-10 Arch Dev Corp PROCEDE ET APPAREILLAGE DESTINES A PRODUIRE DU Bi-212 ET UNE UTILISATION DE CEUX-CI
US5729821A (en) * 1996-12-10 1998-03-17 Lockheed Martin Energy Research Coirporation Concentration of perrhenate and pertechnetate solutions
EP0984978A4 (fr) * 1997-03-14 2002-01-09 Transgenomic Inc Affichage de separations polyonucleotidiques sous la forme d'un arrangement de bandes
US5854968A (en) * 1997-06-09 1998-12-29 Arch Development Corporation Process and apparatus for the production of BI-213 cations
EP1073609A4 (fr) * 1998-03-30 2002-08-28 Sloan Kettering Inst Cancer Generateur de bismuth-213 et ses utilisations
US6153154A (en) * 1998-05-27 2000-11-28 Battelle Memorial Institute Method for sequential injection of liquid samples for radioisotope separations
ES2203856T3 (es) * 1998-06-22 2004-04-16 European Community Metodo y aparato para la preparacion de bi-213 para uso terapeutico humano.
US6245305B1 (en) * 1998-11-10 2001-06-12 Battelle Memorial Institute Method of separating and purifying gadolinium-153
US6157036A (en) * 1998-12-02 2000-12-05 Cedars-Sinai Medical Center System and method for automatically eluting and concentrating a radioisotope
CA2393849A1 (fr) * 1999-12-22 2001-06-28 Transgenomic, Inc. Systeme et procede de chromatographie de polynucleotides par ions apparies automatisee
ATE527038T1 (de) * 2001-06-22 2011-10-15 Pg Res Foundation Inc Automatisiertes system und verfahren zur trennung von radionukliden

Also Published As

Publication number Publication date
CN1306981C (zh) 2007-03-28
CN1518475A (zh) 2004-08-04
US6770195B2 (en) 2004-08-03
ZA200309765B (en) 2004-09-28
US20020195391A1 (en) 2002-12-26
ATE408818T1 (de) 2008-10-15
CA2451154A1 (fr) 2003-01-03
EP1404429B1 (fr) 2008-09-17
EP1404429A4 (fr) 2005-02-02
WO2003000375A1 (fr) 2003-01-03
EA005712B1 (ru) 2005-04-28
EA200301245A1 (ru) 2004-06-24
EP1404429A1 (fr) 2004-04-07
CA2451154C (fr) 2012-02-07
DE60228960D1 (de) 2008-10-30
JP2005500517A (ja) 2005-01-06
JP4309254B2 (ja) 2009-08-05

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
MK14 Patent ceased section 143(a) (annual fees not paid) or expired