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ATE58537T1 - Verfahren zur herstellung von imidazopyridinen. - Google Patents

Verfahren zur herstellung von imidazopyridinen.

Info

Publication number
ATE58537T1
ATE58537T1 AT87401353T AT87401353T ATE58537T1 AT E58537 T1 ATE58537 T1 AT E58537T1 AT 87401353 T AT87401353 T AT 87401353T AT 87401353 T AT87401353 T AT 87401353T AT E58537 T1 ATE58537 T1 AT E58537T1
Authority
AT
Austria
Prior art keywords
imidazopyridines
preparation
Prior art date
Application number
AT87401353T
Other languages
English (en)
Inventor
Guy Rossey
David Long
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Application granted granted Critical
Publication of ATE58537T1 publication Critical patent/ATE58537T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT87401353T 1986-06-27 1987-06-17 Verfahren zur herstellung von imidazopyridinen. ATE58537T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8609330A FR2600650B1 (fr) 1986-06-27 1986-06-27 Procede de preparation d'imidazopyridines et composes intermediaires
EP87401353A EP0251859B1 (de) 1986-06-27 1987-06-17 Verfahren zur Herstellung von Imidazopyridinen

Publications (1)

Publication Number Publication Date
ATE58537T1 true ATE58537T1 (de) 1990-12-15

Family

ID=9336785

Family Applications (1)

Application Number Title Priority Date Filing Date
AT87401353T ATE58537T1 (de) 1986-06-27 1987-06-17 Verfahren zur herstellung von imidazopyridinen.

Country Status (21)

Country Link
US (1) US4794185A (de)
EP (1) EP0251859B1 (de)
JP (1) JPH0653740B2 (de)
KR (1) KR940006594B1 (de)
AR (1) AR243188A1 (de)
AT (1) ATE58537T1 (de)
AU (1) AU7477287A (de)
CA (1) CA1324138C (de)
DE (1) DE3766300D1 (de)
DK (1) DK169505B1 (de)
ES (1) ES2019646B3 (de)
FI (1) FI872850A7 (de)
FR (1) FR2600650B1 (de)
GR (1) GR3001118T3 (de)
HU (1) HU204826B (de)
IE (1) IE60467B1 (de)
IL (1) IL82982A (de)
NO (1) NO167392C (de)
NZ (1) NZ220853A (de)
PT (1) PT85188B (de)
ZA (1) ZA874643B (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2032455T3 (es) * 1986-01-22 1993-02-16 Synthelabo Procedimiento para preparar derivados de 3-acilaminometil-imidazo (-1,2-a)piridinas.
FR2615513B1 (fr) * 1987-05-21 1989-07-13 Synthelabo Derives d'acylaminomethyl-3 tetrahydro-5,6,7,8 imidazo(1,2-a)pyridines, leur preparation et leur application en therapeutique
WO1999063977A2 (en) 1998-06-09 1999-12-16 Takeda Chemical Industries, Ltd. Pharmaceutical combination comprising a tricyclic compound and at least one of zolpidem, zopiclone, triazolam and brotizolam for treating or preventing sleep disorders
ES2151834B1 (es) * 1998-08-06 2001-08-16 Sint Quimica Sa Procedimiento para preparar n,n,6-trimetil-2-(4-metilfenil)-imidazo-(1,2-a)-piridina-3-acetamida y sus sales.
ES2195510T3 (es) 1999-03-25 2003-12-01 Synthon Bv Derivados de imidazopiridina y procedimiento para prepararlos.
DE60020814T2 (de) * 1999-03-25 2006-05-04 Synthon B.V. Zolpidem salze
US6333345B1 (en) * 1999-05-14 2001-12-25 Sepracor, Inc. Methods of using and compositions comprising N-desmethylzolpidem
US6399621B1 (en) 1999-08-10 2002-06-04 American Cyanamid Company N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1, 5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
US6485746B1 (en) 2000-08-25 2002-11-26 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US20030091632A1 (en) * 1999-08-26 2003-05-15 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto
US6384221B1 (en) * 1999-09-02 2002-05-07 Neurocrine Biosciences, Inc. Polymorphs of N-methyl-N-(3-{3-[2-thienylcarbonyl]-pyrazol-[1,5-α]-pyrimidin-7-yl}phenyl)acetamide and compositions and methods related thereto
AU5066101A (en) * 2000-04-13 2001-10-30 Synthon B.V. Modified release formulations containing a hypnotic agent
ES2248321T3 (es) * 2000-04-24 2006-03-16 Teva Pharmaceutical Industries Ltd. Hemitartrato de zolpidem.
EP1604663A1 (de) * 2000-04-24 2005-12-14 Teva Pharmaceutical Industries Ltd Zolpidem Hemitartrat Solvat Form H
IT1318624B1 (it) 2000-07-14 2003-08-27 Dinamite Dipharma S P A In For Processo per la preparazione di 2-fenil-imidazo (1,2-a)piridin-3-acetammidi.
WO2002014306A1 (en) * 2000-08-17 2002-02-21 Cilag Ag Process for the preparation of imidazopyridines
US6596731B2 (en) 2001-03-27 2003-07-22 Hoffmann-La Roche Inc. Substituted imidazo[1,2-A] pyridine derivatives
DE10121638A1 (de) * 2001-05-03 2002-11-14 Boehringer Ingelheim Pharma Verfahren zur Herstellung von Imidazopyridinen
US20020183522A1 (en) 2001-05-03 2002-12-05 Markus Sauter Process for preparing zolpidem
DE60320808D1 (de) * 2002-07-15 2008-06-19 Scinopharm Taiwan Ltd Verfahren zur herstellung von imidazo(1,2-a)pyridin-3-acetamiden
JP2006516139A (ja) * 2002-12-18 2006-06-22 マリンクロッド・インコーポレイテッド ヘテロアリールアセトアミド化合物の合成
US20040241100A1 (en) * 2003-03-17 2004-12-02 Fabre Kramer Pharmaceutical, Inc. Nasally administrable compositions of zolpidem and methods of use
GB0311457D0 (en) * 2003-05-19 2003-06-25 Sciencom Ltd New therapeutic use
DK1691811T3 (da) 2003-12-11 2014-10-20 Sunovion Pharmaceuticals Inc Kombination af et sedativ og en neurotransmittermodulator og fremgangsmåder til forbedring af søvnkvaliteten og behandling af depression
ATE451371T1 (de) * 2004-06-22 2009-12-15 Mallinckrodt Inc Synthese von heteroarylacetamiden aus reaktionsmischungen mit reduziertem wassergehalt
WO2006008636A2 (en) * 2004-07-16 2006-01-26 Ranbaxy Laboratories Limited Processes for the preparation of zolpidem and its hemitartrate
EP2258359A3 (de) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenese durch Modulation des Muscarinrezeptors mit Sabcomelin
EP2275096A3 (de) 2005-08-26 2011-07-13 Braincells, Inc. Neurogenese durch modulation des Muscarinrezeptors
JP2009510163A (ja) * 2005-10-03 2009-03-12 マリンクロッド・インコーポレイテッド ヘミ酒石酸および酒石酸ゾルピデム多形の製造方法
AU2006303000A1 (en) * 2005-10-17 2007-04-26 Mallinckrodt Inc. Polymorph transformation of Zolpidem in tablet matrix
EP1940389A2 (de) 2005-10-21 2008-07-09 Braincells, Inc. Modulation von neurogenese durch pde-hemmung
JP2009513672A (ja) 2005-10-31 2009-04-02 ブレインセルス，インコーポレイティド 神経発生のｇａｂａ受容体媒介調節
DE602006008339D1 (en) 2005-11-18 2009-09-17 Synhton B V Zolpidemtabletten
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
EP2382975A3 (de) 2006-05-09 2012-02-29 Braincells, Inc. Neurogenese mittels Angiotensin-Modulation
CA2651862A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. 5 ht receptor mediated neurogenesis
KR20090064418A (ko) * 2006-09-08 2009-06-18 브레인셀즈 인코퍼레이션 4-아실아미노피리딘 유도체 포함 조합물
US20080145425A1 (en) * 2006-12-15 2008-06-19 Pliva Research & Development Limited Pharmaceutical composition of zolpidem
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
CN103360387B (zh) * 2012-03-28 2016-12-14 江苏豪森药业集团有限公司 一种制备化合物唑吡坦的方法
KR101704589B1 (ko) * 2016-07-12 2017-02-08 주식회사 뉴트라팜텍 후박 추출물 및 신이 추출물의 혼합물을 유효성분으로 함유하는 치주조직 성장 촉진용 및 치주염 예방 또는 치료용 약학적 조성물
CN107793415A (zh) * 2016-12-01 2018-03-13 湖南省食品药品检验研究院 酒石酸唑吡坦杂质的合成方法
CN106749237A (zh) * 2016-12-28 2017-05-31 江苏豪森药业集团有限公司 酒石酸唑吡坦及其中间体的制备方法
CN114057727B (zh) * 2020-07-31 2024-02-27 株洲千金药业股份有限公司 一种唑吡坦中间体的合成方法
CN114057725B (zh) * 2020-07-31 2024-01-16 株洲千金药业股份有限公司 一种酒石酸唑吡坦的合成方法
CN114057726A (zh) * 2020-07-31 2022-02-18 株洲千金药业股份有限公司 一种唑吡坦盐酸盐的合成方法
CN114249668B (zh) * 2020-09-25 2024-08-23 鲁南制药集团股份有限公司 一种唑吡坦中间体n,n-二甲基-2-氧乙酰胺的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GR68765B (de) * 1979-06-20 1982-02-17 Rohm & Haas
FR2492382A1 (fr) * 1980-10-22 1982-04-23 Synthelabo Derives d'imidazo (1,2-a) pyridine, leur preparation et leur application en therapeutique

Also Published As

Publication number Publication date
HU204826B (en) 1992-02-28
IE871723L (en) 1987-12-27
ES2019646B3 (es) 1991-07-01
JPH0653740B2 (ja) 1994-07-20
EP0251859A2 (de) 1988-01-07
EP0251859B1 (de) 1990-11-22
KR940006594B1 (ko) 1994-07-23
FI872850A0 (fi) 1987-06-26
DK328187D0 (da) 1987-06-26
HUT44547A (en) 1988-03-28
PT85188B (pt) 1990-03-30
AR243188A1 (es) 1993-07-30
FR2600650B1 (fr) 1988-09-09
US4794185A (en) 1988-12-27
FI872850A7 (fi) 1987-12-28
NO167392B (no) 1991-07-22
KR880000433A (ko) 1988-03-25
DK169505B1 (da) 1994-11-14
JPS638384A (ja) 1988-01-14
AU7477287A (en) 1988-01-07
NZ220853A (en) 1989-09-27
FR2600650A1 (fr) 1987-12-31
ZA874643B (en) 1988-02-24
NO872682D0 (no) 1987-06-26
IE60467B1 (en) 1994-07-13
EP0251859A3 (en) 1989-07-19
PT85188A (fr) 1987-07-01
DE3766300D1 (de) 1991-01-03
IL82982A0 (en) 1987-12-20
DK328187A (da) 1987-12-28
GR3001118T3 (en) 1992-05-12
CA1324138C (en) 1993-11-09
NO167392C (no) 1991-10-30
IL82982A (en) 1992-03-29
NO872682L (no) 1987-12-28

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