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ATE552838T1 - Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac - Google Patents

Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac

Info

Publication number
ATE552838T1
ATE552838T1 AT04818514T AT04818514T ATE552838T1 AT E552838 T1 ATE552838 T1 AT E552838T1 AT 04818514 T AT04818514 T AT 04818514T AT 04818514 T AT04818514 T AT 04818514T AT E552838 T1 ATE552838 T1 AT E552838T1
Authority
AT
Austria
Prior art keywords
aqueous solution
bromefenac
aminoglycoside antibiotic
acceptable salt
pharmacologically acceptable
Prior art date
Application number
AT04818514T
Other languages
English (en)
Inventor
Shirou Sawa
Original Assignee
Senju Pharma Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senju Pharma Co filed Critical Senju Pharma Co
Application granted granted Critical
Publication of ATE552838T1 publication Critical patent/ATE552838T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/7036—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin having at least one amino group directly attached to the carbocyclic ring, e.g. streptomycin, gentamycin, amikacin, validamycin, fortimicins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/16—Otologicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT04818514T 2003-11-14 2004-11-12 Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac ATE552838T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003384646 2003-11-14
PCT/JP2004/016849 WO2005046700A1 (ja) 2003-11-14 2004-11-12 アミノグリコシド系抗生物質およびブロムフェナクを含有する水溶液製剤

Publications (1)

Publication Number Publication Date
ATE552838T1 true ATE552838T1 (de) 2012-04-15

Family

ID=34587329

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04818514T ATE552838T1 (de) 2003-11-14 2004-11-12 Wässrige lösung mit aminoglykosid-antibiotikum und bromfenac

Country Status (9)

Country Link
US (1) US7829544B2 (de)
EP (1) EP1683526B1 (de)
JP (1) JP4674162B2 (de)
KR (1) KR101052705B1 (de)
CN (1) CN100551378C (de)
AT (1) ATE552838T1 (de)
ES (1) ES2381672T3 (de)
PL (1) PL1683526T3 (de)
WO (1) WO2005046700A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101059711B1 (ko) * 2003-01-21 2011-08-29 센주 세이야꾸 가부시키가이샤 2-아미노-3-(4-브로모벤조일)페닐아세트산 함유 수성액제
ATE520394T1 (de) 2004-11-05 2011-09-15 Senju Pharma Co Wässrige augentropfen mit beschleunigter intraokularer migration
PL1921919T3 (pl) * 2005-07-14 2012-09-28 Lithera Inc Ulepszona lipolityczna formulacja o podtrzymywanym uwalnianiu do traktowania lokalnej tkanki tłuszczowej
EP2077830B1 (de) * 2006-10-17 2012-11-07 Lithera, Inc. Prozesse, zusammensetzungen u. formulierungen zur behandlung der schilddrüsen augenkrankheit
CN101313899B (zh) * 2007-06-01 2012-02-29 北京德众万全药物技术开发有限公司 一种含有溴芬酸钠的眼用药物组合物
BRPI0913417B1 (pt) * 2008-06-12 2021-06-08 Foresight Biotherapeutics, Inc composição oftálmica estável adequada para administração tópica ao olho compreendendo iodopovidona e um esteroide
US9132084B2 (en) * 2009-05-27 2015-09-15 Neothetics, Inc. Methods for administration and formulations for the treatment of regional adipose tissue
GB2484843A (en) * 2009-10-15 2012-04-25 Johnson Matthey Plc Polymorphs of Bromfenac sodium
CN102869363A (zh) * 2010-01-15 2013-01-09 利赛拉公司 冻干的块状制剂
CN102557976B (zh) * 2010-12-15 2015-06-10 辽宁盛京制药有限公司 溴芬酸有机盐及其制备方法、其组合物及用途
CN102526738B (zh) * 2010-12-27 2016-03-30 沈阳兴齐眼药股份有限公司 一种复方眼用制剂、其制备方法和用途
CA2824433C (en) 2011-01-18 2019-11-12 Senju Pharmaceutical Co., Ltd. Aqueous liquid bromfenac composition having preservative efficacy
JP6012231B2 (ja) * 2011-04-08 2016-10-25 ロート製薬株式会社 ブロムフェナク含有組成物
TWI604858B (zh) * 2012-03-28 2017-11-11 參天製藥股份有限公司 含有２－胺基－３－（４－溴苯甲醯基）苯基醋酸之水性組成物及其製造方法
GB201208080D0 (en) * 2012-05-09 2012-06-20 Norton Healthcare Ltd Tobramycin formulation
EP2919755B1 (de) * 2012-11-19 2018-02-21 Bausch & Lomb Incorporated Wässrige flüssigzusammensetzung mit 2-amino-3-(4-brombenzoyl-)phenylessigsäure
CN112274489A (zh) 2013-03-14 2021-01-29 红山生物医药有限公司 抗呕吐缓释固体剂型
US9675588B2 (en) * 2014-03-11 2017-06-13 Redhill Biopharma Ltd. Ondansetron extended release solid dosage forms for treating either nausea, vomiting or diarrhea symptoms
CN108056229A (zh) * 2017-12-30 2018-05-22 天津赫莱恩特生物科技有限公司 一种应用于抗生素溶液中的稳定剂组合物的制备方法
US20240082188A1 (en) * 2021-01-21 2024-03-14 Taejoon Pharmaceutical Co., Ltd. Ophthalmic composition
CN118613267A (zh) * 2022-01-21 2024-09-06 千寿美国有限公司 水性液体制剂
WO2025018419A1 (ja) * 2023-07-20 2025-01-23 センジュ ユーエスエー、インコーポレイテッド 水性液剤

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5414011A (en) * 1987-09-11 1995-05-09 Syntex (U.S.A.) Inc. Preservative system for ophthalmic formulations
CA1325382C (en) * 1988-01-27 1993-12-21 Takahiro Ogawa Locally administrable therapeutic composition for inflammatory disease
IT1216686B (it) 1988-04-01 1990-03-08 Chiesi Farma Spa Formulazioni farmaceutiche acquose di piroxicam e procedimento per laloro preparazione.
US5340572A (en) 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
ES2079320B1 (es) 1994-05-17 1996-10-16 Cusi Lab Disolucion oftalmica a base de un diclofenaco y tobramicina y sus aplicaciones.
US5475034A (en) 1994-06-06 1995-12-12 Alcon Laboratories, Inc. Topically administrable compositions containing 3-benzoylphenylacetic acid derivatives for treatment of ophthalmic inflammatory disorders
JP3170619B2 (ja) * 1995-04-20 2001-05-28 参天製薬株式会社 有機アミンを配合したプラノプロフェン点眼液
AR004214A1 (es) * 1995-10-12 1998-11-04 Otsuka Pharma Co Ltd Una preparación de gotas oftálmicas para la cura de enfermedades oftálmicas
JP3093661B2 (ja) 1995-10-12 2000-10-03 大塚製薬株式会社 眼疾患治療剤
US6440964B1 (en) * 1998-09-30 2002-08-27 Alcon Manufacturing, Ltd. Compositions and methods for treating ophthalmic and otic infections
JP2000212088A (ja) 1999-01-27 2000-08-02 Kobayashi Kako Kk 難溶性抗ウイルス剤の水溶液
AR031135A1 (es) 2000-10-10 2003-09-10 Upjohn Co Composiciones de antibiotico topico para el tratamiento de infecciones oculares

Also Published As

Publication number Publication date
US20070082857A1 (en) 2007-04-12
JPWO2005046700A1 (ja) 2007-05-24
EP1683526A1 (de) 2006-07-26
ES2381672T3 (es) 2012-05-30
JP4674162B2 (ja) 2011-04-20
CN1882349A (zh) 2006-12-20
KR20060120084A (ko) 2006-11-24
PL1683526T3 (pl) 2012-09-28
EP1683526A4 (de) 2008-04-09
WO2005046700A1 (ja) 2005-05-26
US7829544B2 (en) 2010-11-09
CN100551378C (zh) 2009-10-21
KR101052705B1 (ko) 2011-08-01
EP1683526B1 (de) 2012-04-11

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