ATE550354T1 - Humane ringspezifische bnp-antikörper - Google Patents
Humane ringspezifische bnp-antikörperInfo
- Publication number
- ATE550354T1 ATE550354T1 AT06734524T AT06734524T ATE550354T1 AT E550354 T1 ATE550354 T1 AT E550354T1 AT 06734524 T AT06734524 T AT 06734524T AT 06734524 T AT06734524 T AT 06734524T AT E550354 T1 ATE550354 T1 AT E550354T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- human ring
- bnp antibodies
- specific
- specific bnp
- Prior art date
Links
- 101500026735 Homo sapiens Brain natriuretic peptide 32 Proteins 0.000 abstract 3
- 239000012634 fragment Substances 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 238000011002 quantification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/26—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against hormones ; against hormone releasing or inhibiting factors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Endocrinology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US65382905P | 2005-02-17 | 2005-02-17 | |
US11/135,040 US7731965B2 (en) | 2005-02-17 | 2005-05-23 | Human ring specific BNP antibodies |
PCT/US2006/004318 WO2006088700A2 (en) | 2005-02-17 | 2006-02-08 | Human ring specific bnp antibodies |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE550354T1 true ATE550354T1 (de) | 2012-04-15 |
Family
ID=36716625
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06734524T ATE550354T1 (de) | 2005-02-17 | 2006-02-08 | Humane ringspezifische bnp-antikörper |
Country Status (7)
Country | Link |
---|---|
US (1) | US7731965B2 (de) |
EP (1) | EP1853629B1 (de) |
JP (1) | JP5159324B2 (de) |
AT (1) | ATE550354T1 (de) |
CA (1) | CA2598253C (de) |
ES (1) | ES2383818T3 (de) |
WO (1) | WO2006088700A2 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7731965B2 (en) | 2005-02-17 | 2010-06-08 | Abbott Lab | Human ring specific BNP antibodies |
US7939069B2 (en) | 2005-11-09 | 2011-05-10 | Abbott Laboratories | Human BNP immunospecific antibodies |
JP5364378B2 (ja) * | 2005-11-09 | 2013-12-11 | アボット・ラボラトリーズ | ヒトbnp免疫特異的抗体 |
US20080064045A1 (en) * | 2006-09-07 | 2008-03-13 | Huaiqin Wu | Biomarker fragments for the detection of human BNP |
EP2295445A1 (de) * | 2006-09-08 | 2011-03-16 | Mayo Foundation for Medical Education and Research | Aquaretische und natriuretische Polypeptide ohne Gefäßerweiterungsaktivität |
CA2667012A1 (en) * | 2006-10-26 | 2008-05-02 | Abbott Laboratories | Immunoassay of analytes in samples containing endogenous anti-analyte antibodies |
FI20075251A0 (fi) | 2007-04-13 | 2007-04-13 | Hytest Oy | Immunomääritys epästabiilien antigeenien määrittämiseksi |
WO2008137991A1 (en) * | 2007-05-08 | 2008-11-13 | Abbott Laboratories | Human b-type natriuretic peptide assay having reduced cross-reactivity with other peptide forms |
WO2010012509A1 (en) | 2008-08-01 | 2010-02-04 | Bio-Rad Pasteur | Method for the in vitro diagnosis of stroke |
WO2010012834A1 (en) * | 2008-08-01 | 2010-02-04 | Bio-Rad Pasteur | Method for the in vitro diagnosis of stroke |
FR2919611B1 (fr) * | 2007-08-03 | 2009-10-23 | Bio Rad Pasteur Sa | Nouvel epitope du bnp (1-32) et anticorps diriges contre cet epitope |
PL2222697T3 (pl) * | 2007-11-01 | 2013-05-31 | Astellas Pharma Inc | Immunosupresyjne polipeptydy i kwasy nukleinowe |
JP5795256B2 (ja) * | 2009-07-31 | 2015-10-14 | バイオ−ラッド・イノベーションズBio−Rad Innovations | 卒中のインビトロ診断のための方法 |
KR20140059249A (ko) | 2011-08-30 | 2014-05-15 | 메이오 파운데이션 포 메디칼 에쥬케이션 앤드 리써치 | 나트륨이뇨 폴리펩티드 |
US9611305B2 (en) | 2012-01-06 | 2017-04-04 | Mayo Foundation For Medical Education And Research | Treating cardiovascular or renal diseases |
JPWO2016194855A1 (ja) * | 2015-05-29 | 2018-06-07 | 株式会社 イギス | 環状ペプチド並びに該環状ペプチドを含む医薬、外用剤および化粧料 |
WO2020141157A1 (en) * | 2018-12-31 | 2020-07-09 | Hytest Ltd | Methods and biomarkers for predicting efficacy and evaluation of treatment with drugs modulating neprilysin activity. |
WO2023190560A1 (ja) * | 2022-03-31 | 2023-10-05 | デンカ株式会社 | ヒトb型ナトリウム利尿ペプチド又はその前駆体若しくは分解物を検出するための方法、組成物、及びキット |
Family Cites Families (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4399216A (en) | 1980-02-25 | 1983-08-16 | The Trustees Of Columbia University | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4634665A (en) | 1980-02-25 | 1987-01-06 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US5179017A (en) | 1980-02-25 | 1993-01-12 | The Trustees Of Columbia University In The City Of New York | Processes for inserting DNA into eucaryotic cells and for producing proteinaceous materials |
US4510245A (en) | 1982-11-18 | 1985-04-09 | Chiron Corporation | Adenovirus promoter system |
US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
AU572173B2 (en) | 1983-08-29 | 1988-05-05 | Institut De Recherches Cliniques De Montreal | Natriuretic factors |
US5168062A (en) | 1985-01-30 | 1992-12-01 | University Of Iowa Research Foundation | Transfer vectors and microorganisms containing human cytomegalovirus immediate-early promoter-regulatory DNA sequence |
US4968615A (en) | 1985-12-18 | 1990-11-06 | Ciba-Geigy Corporation | Deoxyribonucleic acid segment from a virus |
DE3750503T2 (de) | 1986-10-22 | 1995-02-09 | Abbott Lab | Chemilumineszierende Acridinium- und Phenantridiniumsalze. |
US5114923A (en) | 1988-05-31 | 1992-05-19 | California Biotechnology Inc. | Recombinant techniques for production of novel natriuretic and vasodilator peptides |
CA1339210C (en) | 1988-05-31 | 1997-08-05 | John Lewicki | Recombinant techniques for production of novel natriuretic and vasodilator peptides |
DE3905441C2 (de) | 1989-02-22 | 1994-01-20 | Minnesota Mining & Mfg | Metallische innere Umhüllung für eine elektrische Kabelverbindung |
US20020086843A1 (en) | 1989-03-01 | 2002-07-04 | Daiichi Pure Chemicals Co., Ltd. | Physiologically active polypeptide and DNA |
JP2676114B2 (ja) | 1990-04-16 | 1997-11-12 | 塩野義製薬株式会社 | hBNPを認識するモノクローナル抗体および該抗体を用いるhBNPの免疫測定法 |
US5545806A (en) | 1990-08-29 | 1996-08-13 | Genpharm International, Inc. | Ransgenic non-human animals for producing heterologous antibodies |
JP2665850B2 (ja) | 1991-11-14 | 1997-10-22 | 塩野義製薬株式会社 | hBNPのC端を認識するモノクロ−ナル抗体 |
US6090382A (en) | 1996-02-09 | 2000-07-18 | Basf Aktiengesellschaft | Human antibodies that bind human TNFα |
CA2248140C (en) | 1996-03-04 | 2005-02-01 | Ronald P. Mischak | Assay and reagents for quantifying hbnp |
CN1161609C (zh) * | 1997-09-11 | 2004-08-11 | 盐野义制药株式会社 | 哺乳类γ-BNP衍生物特异的免疫测定方法及其试剂盒 |
CA2306751C (en) | 1997-10-24 | 2006-12-12 | Shionogi & Co., Ltd. | Method for inhibiting degradation of natriuretic peptides and improved method for measuring natgriuretic peptides with the use of the same |
US6117644A (en) | 1998-06-04 | 2000-09-12 | Ottawa Heart Institute Research Corporation | Predicting and detecting cardiac allograft rejection |
DE19847690A1 (de) | 1998-10-15 | 2000-04-20 | Brahms Diagnostica Gmbh | Verfahren und Substanzen für die Diagnose und Therapie von Sepsis und sepsisähnlichen systemischen Infektionen |
JP3297392B2 (ja) | 1999-01-28 | 2002-07-02 | 沖電気工業株式会社 | 半導体記憶装置 |
US7632647B2 (en) | 2001-04-13 | 2009-12-15 | Biosite Incorporated | Use of B-type natriuretic peptide as a prognostic indicator in acute coronary syndromes |
US20030199000A1 (en) | 2001-08-20 | 2003-10-23 | Valkirs Gunars E. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US20040209307A1 (en) | 2001-08-20 | 2004-10-21 | Biosite Incorporated | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US20040219509A1 (en) | 2001-08-20 | 2004-11-04 | Biosite, Inc. | Diagnostic markers of stroke and cerebral injury and methods of use thereof |
US6461828B1 (en) | 2001-09-04 | 2002-10-08 | Syn X Pharma | Conjunctive analysis of biological marker expression for diagnosing organ failure |
US7396913B2 (en) | 2002-10-14 | 2008-07-08 | Abbott Laboratories | Erythropoietin receptor binding antibodies |
US8263325B2 (en) | 2002-11-15 | 2012-09-11 | Ottawa Heart Institute Research Corporation | Predicting, detecting and monitoring treatment of cardiomyopathies and myocarditis |
WO2004082639A2 (en) | 2003-03-19 | 2004-09-30 | Baylor College Of Medicine | Detecting coronary artery disease with bnp during stress testing |
US7341838B2 (en) | 2003-04-17 | 2008-03-11 | Biosite Incorporated | Polypeptides related to natriuretic peptides and methods of their identification and use |
US7445933B2 (en) | 2003-07-16 | 2008-11-04 | Abbott Laboratories, Inc. | Stable calibrators or controls for measuring human natriuretic peptides |
AU2005299355A1 (en) | 2004-10-27 | 2006-05-04 | Medimmune, Llc | Modulation of antibody specificity by tailoring the affinity to cognate antigens |
US7731965B2 (en) | 2005-02-17 | 2010-06-08 | Abbott Lab | Human ring specific BNP antibodies |
-
2005
- 2005-05-23 US US11/135,040 patent/US7731965B2/en active Active
-
2006
- 2006-02-08 JP JP2007556184A patent/JP5159324B2/ja not_active Expired - Fee Related
- 2006-02-08 AT AT06734524T patent/ATE550354T1/de active
- 2006-02-08 ES ES06734524T patent/ES2383818T3/es active Active
- 2006-02-08 CA CA2598253A patent/CA2598253C/en not_active Expired - Fee Related
- 2006-02-08 WO PCT/US2006/004318 patent/WO2006088700A2/en active Application Filing
- 2006-02-08 EP EP06734524A patent/EP1853629B1/de active Active
Also Published As
Publication number | Publication date |
---|---|
US7731965B2 (en) | 2010-06-08 |
CA2598253C (en) | 2013-08-06 |
CA2598253A1 (en) | 2006-08-24 |
US20060183154A1 (en) | 2006-08-17 |
WO2006088700A2 (en) | 2006-08-24 |
JP5159324B2 (ja) | 2013-03-06 |
EP1853629B1 (de) | 2012-03-21 |
ES2383818T3 (es) | 2012-06-26 |
EP1853629A2 (de) | 2007-11-14 |
WO2006088700A3 (en) | 2006-11-02 |
JP2008530207A (ja) | 2008-08-07 |
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