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ATE541919T1 - Herstellung eines proteins in serumfreier zellkultur, die ein proteinhydrolysat aus pflanzen enthält - Google Patents

Herstellung eines proteins in serumfreier zellkultur, die ein proteinhydrolysat aus pflanzen enthält

Info

Publication number
ATE541919T1
ATE541919T1 AT06708017T AT06708017T ATE541919T1 AT E541919 T1 ATE541919 T1 AT E541919T1 AT 06708017 T AT06708017 T AT 06708017T AT 06708017 T AT06708017 T AT 06708017T AT E541919 T1 ATE541919 T1 AT E541919T1
Authority
AT
Austria
Prior art keywords
cell culture
protein
serum
cells
production
Prior art date
Application number
AT06708017T
Other languages
English (en)
Inventor
Ida Knudsen
Original Assignee
Novo Nordisk Healthcare Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36607297&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE541919(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novo Nordisk Healthcare Ag filed Critical Novo Nordisk Healthcare Ag
Application granted granted Critical
Publication of ATE541919T1 publication Critical patent/ATE541919T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6437—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0043—Medium free of human- or animal-derived components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21021—Coagulation factor VIIa (3.4.21.21)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/76—Undefined extracts from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00—Genetically modified cells
    • C12N2510/02—Cells for production

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT06708017T 2005-02-11 2006-02-06 Herstellung eines proteins in serumfreier zellkultur, die ein proteinhydrolysat aus pflanzen enthält ATE541919T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200500204 2005-02-11
PCT/EP2006/050669 WO2006084826A1 (en) 2005-02-11 2006-02-06 Production of a polypeptide in a serum-free cell culture liquid containing plant protein hydrolysate

Publications (1)

Publication Number Publication Date
ATE541919T1 true ATE541919T1 (de) 2012-02-15

Family

ID=36607297

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06708017T ATE541919T1 (de) 2005-02-11 2006-02-06 Herstellung eines proteins in serumfreier zellkultur, die ein proteinhydrolysat aus pflanzen enthält

Country Status (7)

Country Link
US (1) US8530192B2 (de)
EP (1) EP1851305B1 (de)
JP (2) JP5523674B2 (de)
CN (1) CN101120085B (de)
AT (1) ATE541919T1 (de)
ES (1) ES2380485T3 (de)
WO (1) WO2006084826A1 (de)

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Publication number Priority date Publication date Assignee Title
AU2007294731B2 (en) 2006-09-13 2014-04-17 Abbvie Inc. Cell culture improvements
US8911964B2 (en) 2006-09-13 2014-12-16 Abbvie Inc. Fed-batch method of making human anti-TNF-alpha antibody
AU2007323978B2 (en) 2006-11-08 2012-08-16 Wyeth Llc Rationally designed media for cell culture
BR122019022434B8 (pt) * 2007-12-27 2021-07-27 Baxalta GmbH método para cultivar células de mamífero que secretam proteína heteróloga em um sobrenadante de cultura celular
SG195577A1 (en) 2008-10-20 2013-12-30 Abbott Lab Viral inactivation during purification of antibodies
TW201024318A (en) 2008-10-20 2010-07-01 Abbott Lab Isolation and purification of antibodies using protein A affinity chromatography
CA2742107A1 (en) * 2008-11-12 2010-05-20 Baxter International Inc. Method of producing serum-free insulin-free factor vii
FR2948381B1 (fr) * 2009-07-24 2013-07-12 Oncobiotek Procede d'obtention de myofibroblastes.
CA2829180C (en) * 2010-03-05 2019-01-15 Newagriculture, Inc. Leaf protein-lipid-soluble material complexes
EP2702077A2 (de) 2011-04-27 2014-03-05 AbbVie Inc. Verfahren zur steuerung des galactosylierungsprofil von rekombinant exprimierten proteinen
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9334319B2 (en) 2012-04-20 2016-05-10 Abbvie Inc. Low acidic species compositions
US9505833B2 (en) 2012-04-20 2016-11-29 Abbvie Inc. Human antibodies that bind human TNF-alpha and methods of preparing the same
WO2013158273A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Methods to modulate c-terminal lysine variant distribution
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
WO2014035475A1 (en) 2012-09-02 2014-03-06 Abbvie Inc. Methods to control protein heterogeneity
US8921526B2 (en) 2013-03-14 2014-12-30 Abbvie, Inc. Mutated anti-TNFα antibodies and methods of their use
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
BR112015022529A2 (pt) * 2013-03-15 2017-07-18 Genentech Inc meios de cultura de células e processos de produção de anticorpo
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
US20150139988A1 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
CN108624549B (zh) * 2017-03-23 2020-11-20 上海奥浦迈生物科技有限公司 一种cho dg44培养基及其应用
WO2020117949A1 (en) * 2018-12-06 2020-06-11 Inventprise, Llc Bacterial growth on non-animal derived media
RU2741088C1 (ru) * 2019-12-30 2021-01-22 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Композиция на основе гидролизата белка гороха для повышения специфической продуктивности клеточных линий продуцентов и способ её получения
RU2741086C1 (ru) * 2019-12-31 2021-01-22 Федеральное государственное бюджетное учреждение науки институт биоорганической химии им. академиков М.М. Шемякина и Ю.А. Овчинникова Российской академии наук (ИБХ РАН) Композиция на основе гидролизата белка подсолнечника для повышения специфической продуктивности клеточных линий продуцентов и способ её получения

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
AT407255B (de) * 1997-06-20 2001-02-26 Immuno Ag Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons
US6406909B1 (en) * 1998-07-10 2002-06-18 Chugai Seiyaku Kabushiki Kaisha Serum-free medium for culturing animal cells
AT409379B (de) 1999-06-02 2002-07-25 Baxter Ag Medium zur protein- und serumfreien kultivierung von zellen
DE59913565D1 (de) * 1999-08-05 2006-07-27 Baxter Ag Rekombinanter stabiler zellklon, seine herstellung und verwendung
BRPI0109494B8 (pt) * 2000-03-22 2021-05-25 Octagene Gmbh muteína de fator viii, sequência de dna, vetor, processo para produção da muteína de fator viii, composição farmacêutica e uso da muteína do fator viii
EP1325147A2 (de) 2000-10-02 2003-07-09 Novo Nordisk A/S Serumfreie herstellung von rekombinantem faktor vii in säugetierzelle in industriellem umfang
BR0212780A (pt) * 2001-10-02 2004-10-13 Novo Nordisk Healthcare Ag Métodos para produzir polipeptìdeos em células eucarióticas, para cultivar células eucarióticas e para colher polipeptìdeos produzidos por células eucarióticas

Also Published As

Publication number Publication date
JP2014110794A (ja) 2014-06-19
US20080254514A1 (en) 2008-10-16
EP1851305A1 (de) 2007-11-07
JP5523674B2 (ja) 2014-06-18
ES2380485T3 (es) 2012-05-14
CN101120085B (zh) 2011-06-08
WO2006084826A1 (en) 2006-08-17
JP2008529511A (ja) 2008-08-07
EP1851305B1 (de) 2012-01-18
US8530192B2 (en) 2013-09-10
CN101120085A (zh) 2008-02-06

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