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ATE521697T1 - Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion - Google Patents

Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion

Info

Publication number
ATE521697T1
ATE521697T1 AT03721475T AT03721475T ATE521697T1 AT E521697 T1 ATE521697 T1 AT E521697T1 AT 03721475 T AT03721475 T AT 03721475T AT 03721475 T AT03721475 T AT 03721475T AT E521697 T1 ATE521697 T1 AT E521697T1
Authority
AT
Austria
Prior art keywords
tissue
equivalents
research
eye surface
human connective
Prior art date
Application number
AT03721475T
Other languages
English (en)
Inventor
Donald Tan
Leonard Ang
Roger Beuermann
Original Assignee
Singapore Eye Res Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Singapore Eye Res Inst filed Critical Singapore Eye Res Inst
Application granted granted Critical
Publication of ATE521697T1 publication Critical patent/ATE521697T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C12N2500/10—Metals; Metal chelators
    • C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
    • C12N2500/14—Calcium; Ca chelators; Calcitonin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/70—Undefined extracts
    • C12N2500/80—Undefined extracts from animals
    • C12N2500/84—Undefined extracts from animals from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/90—Serum-free medium, which may still contain naturally-sourced components
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    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/11—Epidermal growth factor [EGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/38—Hormones with nuclear receptors
    • C12N2501/39—Steroid hormones
    • C—CHEMISTRY; METALLURGY
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    • C12N2533/00—Supports or coatings for cell culture, characterised by material
    • C12N2533/90—Substrates of biological origin, e.g. extracellular matrix, decellularised tissue
    • C12N2533/92—Amnion; Decellularised dermis or mucosa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Prostheses (AREA)
AT03721475T 2002-03-29 2003-03-28 Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion ATE521697T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36815802P 2002-03-29 2002-03-29
PCT/US2003/009392 WO2003084431A2 (en) 2002-03-29 2003-03-28 Method for growth of human conjunctival tissue equivalents for research, clinical ocular surface transplantation and tissue engineering

Publications (1)

Publication Number Publication Date
ATE521697T1 true ATE521697T1 (de) 2011-09-15

Family

ID=28791886

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03721475T ATE521697T1 (de) 2002-03-29 2003-03-28 Verfahren zum wachstum von menschlichen bindehautgewebeäquivalenten für die forschung, die klinische augenoberflächentransplantation und die geweberekonstruktion

Country Status (7)

Country Link
US (2) US7049139B2 (de)
EP (1) EP1499710B1 (de)
CN (1) CN1649998A (de)
AT (1) ATE521697T1 (de)
AU (1) AU2003224785B2 (de)
HK (1) HK1080111A1 (de)
WO (1) WO2003084431A2 (de)

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AU2003279132A1 (en) * 2002-10-04 2004-05-04 Tissuetech, Inc. Retinal pigment epithelial cell cultures on amniotic membrane and transplantation
DE102005027355A1 (de) * 2005-06-13 2006-12-14 Femtotechnologies Gmbh Verfahren zum Bearbeiten eines organischen Materials
US8338175B2 (en) * 2006-02-24 2012-12-25 Reliance Life Sciences Pvt. Ltd. Conjunctival tissue system
US8372437B2 (en) 2006-08-17 2013-02-12 Mimedx Group, Inc. Placental tissue grafts
JPWO2008105454A1 (ja) 2007-02-28 2010-06-03 千寿製薬株式会社 ラクリチン高発現細胞
US8574567B2 (en) 2007-05-03 2013-11-05 The Brigham And Women's Hospital, Inc. Multipotent stem cells and uses thereof
EP2607477B1 (de) 2007-05-03 2020-09-23 The Brigham and Women's Hospital, Inc. Multipotente stammzellen und ihre verwendung
WO2008143149A1 (ja) * 2007-05-11 2008-11-27 Dai Nippon Printing Co., Ltd. 寸法が保持された細胞シート、その製造方法、及びそのための細胞培養担体
EP3689421B1 (de) 2007-09-07 2025-02-19 MiMedx Group, Inc. Plazentagewebetransplantate und verfahren zur herstellung und verwendung davon
RU2461622C2 (ru) * 2007-11-28 2012-09-20 Огенодженесис, Инк. Биоинженерный конструкт для имплантации ткани и способ изготовления названного биоинженерного конструкта (варианты)
CN104263699A (zh) * 2014-09-19 2015-01-07 江苏华亿细胞组织工程有限公司 细胞移植用临床治疗级真皮多能干细胞规模化制备培养方法
CN104312970A (zh) * 2014-09-19 2015-01-28 朱宁文 一种细胞治疗用临床治疗级表皮干细胞应用人类细胞外基质筛选及规模化培养制备方法
KR102583179B1 (ko) * 2020-11-27 2023-09-26 (주)엑셀세라퓨틱스 칼슘, 상피세포성장인자 및 알부민을 포함하는 각질형성세포 수립 또는 배양용 배지 조성물

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Also Published As

Publication number Publication date
AU2003224785B2 (en) 2008-12-11
AU2003224785A1 (en) 2003-10-20
CN1649998A (zh) 2005-08-03
US7049139B2 (en) 2006-05-23
WO2003084431A3 (en) 2004-04-15
EP1499710A2 (de) 2005-01-26
WO2003084431A2 (en) 2003-10-16
EP1499710A4 (de) 2005-08-31
US7611895B2 (en) 2009-11-03
US20040009590A1 (en) 2004-01-15
EP1499710B1 (de) 2011-08-24
HK1080111A1 (zh) 2006-04-21
US20060177927A1 (en) 2006-08-10

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