ATE495196T1 - Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizität - Google Patents
Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizitätInfo
- Publication number
- ATE495196T1 ATE495196T1 AT04820430T AT04820430T ATE495196T1 AT E495196 T1 ATE495196 T1 AT E495196T1 AT 04820430 T AT04820430 T AT 04820430T AT 04820430 T AT04820430 T AT 04820430T AT E495196 T1 ATE495196 T1 AT E495196T1
- Authority
- AT
- Austria
- Prior art keywords
- peptide
- carrier conjugate
- producing
- peptide carrier
- high immunogenicity
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 7
- 230000005847 immunogenicity Effects 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 abstract 2
- 101000597577 Gluconacetobacter diazotrophicus (strain ATCC 49037 / DSM 5601 / CCUG 37298 / CIP 103539 / LMG 7603 / PAl5) Outer membrane protein Proteins 0.000 abstract 1
- 230000001268 conjugating effect Effects 0.000 abstract 1
- 230000002349 favourable effect Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US53086703P | 2003-12-18 | 2003-12-18 | |
| PCT/EP2004/014160 WO2005058968A1 (en) | 2003-12-18 | 2004-12-10 | A method to make a peptide-carrier conjugate with a high immunogenicity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE495196T1 true ATE495196T1 (de) | 2011-01-15 |
Family
ID=34700173
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04820430T ATE495196T1 (de) | 2003-12-18 | 2004-12-10 | Verfahren zur herstellung eines peptid-träger- konjugats mit hoher immunogenizität |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US20090104220A1 (de) |
| EP (1) | EP1704167B1 (de) |
| AT (1) | ATE495196T1 (de) |
| DE (1) | DE602004031051D1 (de) |
| WO (1) | WO2005058968A1 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2567030C (en) | 2004-06-01 | 2015-10-06 | Elisabetta Bianchi | Stable peptide mimetic of hiv gp41 fusion intermediate |
| WO2009111865A1 (en) * | 2008-03-12 | 2009-09-17 | Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Health | Reagents and methods for detecting influenza virus proteins |
| EP2763696B1 (de) | 2011-10-07 | 2018-09-19 | iSD Immunotech ApS | Identifizierung der immunsuppressiven domänen bei fusionsproteinen von behüllten rna-viren |
| CN102964432B (zh) * | 2012-11-22 | 2014-02-05 | 中国科学院微生物研究所 | 抑制a型流感病毒m1蛋白发生磷酸化的方法及其应用 |
| EP3906931A3 (de) * | 2013-04-10 | 2022-02-23 | iSD Immunotech ApS | Verwendung von immunsuppressiven domänen als arzneimittel |
| US10039816B2 (en) * | 2014-04-30 | 2018-08-07 | Massachusetts Institute Of Technology | Siderophore-based immunization against gram-negative bacteria |
| US9815886B2 (en) | 2014-10-28 | 2017-11-14 | Adma Biologics, Inc. | Compositions and methods for the treatment of immunodeficiency |
| US10259865B2 (en) | 2017-03-15 | 2019-04-16 | Adma Biologics, Inc. | Anti-pneumococcal hyperimmune globulin for the treatment and prevention of pneumococcal infection |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL98845A0 (en) * | 1990-07-19 | 1992-07-15 | Merck & Co Inc | Coconjugate vaccines comprising immunogenic protein,hiv related peptides,and anionic moieties,their preparation and pharmaceutical compositions containing them |
| CA2071088A1 (en) * | 1991-06-19 | 1992-12-20 | Emilio A. Emini | Conjugates of the class ii protein of the outer membrane of neisseria meningitidis and of hiv-1 related peptides, and vaccines containing same |
| GB2271995A (en) * | 1992-10-15 | 1994-05-04 | Merck & Co Inc | HIV peptide conjugated via anionic spacer to protein |
| US5274122A (en) * | 1992-10-15 | 1993-12-28 | Merck & Co., Inc. | Acidic derivatives of homocysteine thiolactone |
| GB2294047A (en) * | 1994-10-14 | 1996-04-17 | Merck & Co Inc | Synthetic peptides for use as epitopes specific for HIV |
| EP1290230A4 (de) * | 2000-06-02 | 2004-10-20 | Merck & Co Inc | Hepatitis c virus konjugate |
-
2004
- 2004-12-10 DE DE602004031051T patent/DE602004031051D1/de not_active Expired - Lifetime
- 2004-12-10 WO PCT/EP2004/014160 patent/WO2005058968A1/en active Application Filing
- 2004-12-10 EP EP04820430A patent/EP1704167B1/de not_active Expired - Lifetime
- 2004-12-10 US US10/583,491 patent/US20090104220A1/en not_active Abandoned
- 2004-12-10 AT AT04820430T patent/ATE495196T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| WO2005058968A1 (en) | 2005-06-30 |
| EP1704167B1 (de) | 2011-01-12 |
| DE602004031051D1 (de) | 2011-02-24 |
| US20090104220A1 (en) | 2009-04-23 |
| EP1704167A1 (de) | 2006-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |