ATE414095T1 - NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE - Google Patents

NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE

Info

Publication number: ATE414095T1
Authority: AT; Austria
Prior art keywords: compounds; production; products containing; medicinal products; glycoside derivatives
Prior art date: 2002-07-11

Application number

AT03763662T

Other languages

German (de)

Inventor

Heiner Glombik

Wendelin Frick

Hubert Heuer

Werner Kramer

Harm Brummerhop

Oliver Plettenburg

Original Assignee

Sanofi Aventis Deutschland

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-11

Filing date

2003-06-27

Publication date

2008-11-15

2003-06-27 Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland

2008-11-15 Application granted granted Critical

2008-11-15 Publication of ATE414095T1 publication Critical patent/ATE414095T1/en

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Engineering & Computer Science (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Molecular Biology (AREA)
Diabetes (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Epidemiology (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Biochemistry (AREA)
Physical Education & Sports Medicine (AREA)
Rheumatology (AREA)
Biotechnology (AREA)
Genetics & Genomics (AREA)
Obesity (AREA)
Virology (AREA)
Psychiatry (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Urology & Nephrology (AREA)
Pulmonology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Immunology (AREA)
Orthopedic Medicine & Surgery (AREA)
Ophthalmology & Optometry (AREA)
Child & Adolescent Psychology (AREA)

AT03763662T 2002-07-11 2003-06-27 NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE ATE414095T1 (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
DE10231370A DE10231370B4 (en)	2002-07-11	2002-07-11	Thiophene glycoside derivatives, medicaments containing these compounds and methods of making these medicaments

Publications (1)

Publication Number	Publication Date
ATE414095T1 true ATE414095T1 (en)	2008-11-15

Family

ID=30009905

Family Applications (4)

Application Number	Title	Priority Date	Filing Date
AT08008079T ATE479697T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
AT03763662T ATE414095T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
AT08009226T ATE477265T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
AT08008232T ATE477266T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
AT08008079T ATE479697T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE

Family Applications After (2)

Application Number	Title	Priority Date	Filing Date
AT08009226T ATE477265T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
AT08008232T ATE477266T1 (en)	2002-07-11	2003-06-27	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE

Country Status (39)

Country	Link
US (2)	US7101856B2 (en)
EP (4)	EP1964845B1 (en)
JP (1)	JP4511927B2 (en)
KR (1)	KR20050021452A (en)
CN (2)	CN100384863C (en)
AR (1)	AR040474A1 (en)
AT (4)	ATE479697T1 (en)
AU (1)	AU2003246620B2 (en)
BR (1)	BR0312513A (en)
CA (1)	CA2493391C (en)
CR (1)	CR7718A (en)
CY (1)	CY1108754T1 (en)
DE (5)	DE10231370B4 (en)
DK (1)	DK1523488T3 (en)
EC (1)	ECSP055531A (en)
ES (1)	ES2316818T3 (en)
HN (1)	HN2003000215A (en)
HR (1)	HRP20050014A2 (en)
IL (2)	IL166058A0 (en)
JO (1)	JO2707B1 (en)
MA (1)	MA27366A1 (en)
ME (1)	MEP60708A (en)
MX (1)	MXPA05000044A (en)
MY (1)	MY137039A (en)
NO (1)	NO20050649L (en)
OA (1)	OA12880A (en)
PA (1)	PA8577101A1 (en)
PE (1)	PE20040655A1 (en)
PL (1)	PL372931A1 (en)
PT (1)	PT1523488E (en)
RS (1)	RS51002B (en)
RU (1)	RU2317300C2 (en)
SI (1)	SI1523488T1 (en)
TN (1)	TNSN05007A1 (en)
TW (1)	TWI318981B (en)
UA (1)	UA78823C2 (en)
UY (1)	UY27891A1 (en)
WO (1)	WO2004007517A1 (en)
ZA (1)	ZA200409779B (en)

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Publication number	Publication date
JO2707B1 (en)	2014-03-15
WO2004007517A1 (en)	2004-01-22
PT1523488E (en)	2009-01-30
ECSP055531A (en)	2005-03-10
PA8577101A1 (en)	2004-02-07
RU2317300C2 (en)	2008-02-20
MY137039A (en)	2008-12-31
SI1523488T1 (en)	2009-04-30
DE50313056D1 (en)	2010-10-14
TWI318981B (en)	2010-01-01
CN100384863C (en)	2008-04-30
JP4511927B2 (en)	2010-07-28
ES2316818T3 (en)	2009-04-16
US20060293252A1 (en)	2006-12-28
UA78823C2 (en)	2007-04-25
EP1964844B1 (en)	2010-09-01
DE50312984D1 (en)	2010-09-23
EP1967523B1 (en)	2010-08-11
ATE477265T1 (en)	2010-08-15
TNSN05007A1 (en)	2007-05-14
CY1108754T1 (en)	2014-04-09
EP1964845A1 (en)	2008-09-03
UY27891A1 (en)	2003-12-31
HK1080482A1 (en)	2006-04-28
IL166058A0 (en)	2006-01-15
KR20050021452A (en)	2005-03-07
IL191926A0 (en)	2008-12-29
OA12880A (en)	2006-09-15
MEP60708A (en)	2011-05-10
US7101856B2 (en)	2006-09-05
CA2493391C (en)	2010-06-15
ZA200409779B (en)	2006-06-28
US20040138143A1 (en)	2004-07-15
MXPA05000044A (en)	2005-04-08
RU2005103602A (en)	2005-07-20
AU2003246620A1 (en)	2004-02-02
EP1964844A1 (en)	2008-09-03
DE50310783D1 (en)	2008-12-24
NO20050649L (en)	2005-04-01
MA27366A1 (en)	2005-06-01
HN2003000215A (en)	2004-07-27
ATE477266T1 (en)	2010-08-15
EP1523488A1 (en)	2005-04-20
PL372931A1 (en)	2005-08-08
EP1964845B1 (en)	2010-08-11
CR7718A (en)	2006-05-11
AR040474A1 (en)	2005-04-06
EP1967523A1 (en)	2008-09-10
DE10231370B4 (en)	2006-04-06
DK1523488T3 (en)	2009-03-16
CN101240000A (en)	2008-08-13
CN1668628A (en)	2005-09-14
ATE479697T1 (en)	2010-09-15
TW200410979A (en)	2004-07-01
DE10231370A1 (en)	2004-02-05
RS51002B (en)	2010-10-31
DE50312983D1 (en)	2010-09-23
EP1523488B1 (en)	2008-11-12
CA2493391A1 (en)	2004-01-22
US7666848B2 (en)	2010-02-23
RS115004A (en)	2007-02-05
BR0312513A (en)	2005-04-12
JP2005536497A (en)	2005-12-02
AU2003246620B2 (en)	2009-03-19
PE20040655A1 (en)	2004-11-15
HRP20050014A2 (en)	2006-04-30

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ATE479697T1 (en)	2010-09-15	NEW THIOPHENE GLYCOSIDE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
ATE342899T1 (en)	2006-11-15	DIPHENYLAZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
ATE338039T1 (en)	2006-09-15	DIPHENYLAZETIDINONE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THEIR USE
DE59909418D1 (en)	2004-06-09	ARYL-SUBSTITUTED PROPANOLAMINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS AND THE USE THEREOF
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ATE350378T1 (en)	2007-01-15	BICYCLIC HETEROCYCLES, MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS, THEIR USE AND METHOD FOR THEIR PRODUCTION
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