ATE386105T1 - Chimäre humane papillomavirus (hpv) l1 moleküle und deren verwendungen - Google Patents
Chimäre humane papillomavirus (hpv) l1 moleküle und deren verwendungenInfo
- Publication number
- ATE386105T1 ATE386105T1 AT01942170T AT01942170T ATE386105T1 AT E386105 T1 ATE386105 T1 AT E386105T1 AT 01942170 T AT01942170 T AT 01942170T AT 01942170 T AT01942170 T AT 01942170T AT E386105 T1 ATE386105 T1 AT E386105T1
- Authority
- AT
- Austria
- Prior art keywords
- hpv
- molecules
- human papillomavirus
- chimeric human
- proteins
- Prior art date
Links
- 241000701806 Human papillomavirus Species 0.000 title 2
- 239000003153 chemical reaction reagent Substances 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 208000009608 Papillomavirus Infections Diseases 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000005875 antibody response Effects 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
- C07K16/084—Papovaviridae, e.g. papillomavirus, polyomavirus, SV40, BK virus, JC virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5258—Virus-like particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/14011—Baculoviridae
- C12N2710/14111—Nucleopolyhedrovirus, e.g. autographa californica nucleopolyhedrovirus
- C12N2710/14141—Use of virus, viral particle or viral elements as a vector
- C12N2710/14143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20023—Virus like particles [VLP]
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US21283900P | 2000-06-21 | 2000-06-21 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE386105T1 true ATE386105T1 (de) | 2008-03-15 |
Family
ID=22792617
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01942170T ATE386105T1 (de) | 2000-06-21 | 2001-06-12 | Chimäre humane papillomavirus (hpv) l1 moleküle und deren verwendungen |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US6908613B2 (de) |
| EP (1) | EP1292328B1 (de) |
| AT (1) | ATE386105T1 (de) |
| AU (2) | AU2001275458B2 (de) |
| CA (1) | CA2411945C (de) |
| CY (1) | CY1108106T1 (de) |
| DE (1) | DE60132770T2 (de) |
| DK (1) | DK1292328T3 (de) |
| ES (1) | ES2301551T3 (de) |
| PT (1) | PT1292328E (de) |
| WO (1) | WO2001097840A1 (de) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CZ301212B6 (cs) | 1998-10-16 | 2009-12-09 | Smithkline Beecham Biologicals S. A. | Vakcinacní prostredek |
| US6908613B2 (en) * | 2000-06-21 | 2005-06-21 | Medimmune, Inc. | Chimeric human papillomavirus (HPV) L1 molecules and uses therefor |
| DE10137102A1 (de) | 2001-07-30 | 2003-02-27 | Deutsches Krebsforsch | Polyvalente Vakzine gegen durch Papillomaviren verursachte Erkrankungen, Verfahren zu deren Herstellung und deren Verwendung |
| GB0206359D0 (en) * | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| GB0206360D0 (en) * | 2002-03-18 | 2002-05-01 | Glaxosmithkline Biolog Sa | Viral antigens |
| US7858098B2 (en) * | 2002-12-20 | 2010-12-28 | Glaxosmithkline Biologicals, S.A. | Vaccine |
| EP1572233B1 (de) * | 2002-12-20 | 2011-03-30 | GlaxoSmithKline Biologicals s.a. | Verwendung von HPV16 und HPV18 VLPs als Vakzine gegen eine oder mehrere onkogene HPV des Typus 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66, 68 |
| WO2004062584A2 (en) * | 2003-01-10 | 2004-07-29 | Regents Of The University Of Colorado | Therapeutic and prophylactic vaccine for the treatment and prevention of papillomavirus infection |
| US20060029612A1 (en) * | 2004-04-15 | 2006-02-09 | Large Scale Biology Corporation | Prevention and treatment of recurrent respiratory papillomatosis |
| US7758866B2 (en) * | 2004-06-16 | 2010-07-20 | Glaxosmithkline Biologicals, S.A. | Vaccine against HPV16 and HPV18 and at least another HPV type selected from HPV 31, 45 or 52 |
| RU2420313C2 (ru) * | 2004-06-16 | 2011-06-10 | ГлаксоСмитКлайн Байолоджикалз с.а. | Вакцина против вирусов папилломы человека hpv 16 и hpv 18 и по меньшей мере еще одного типа hpv, выбранного из hpv 31, 45 или 52 |
| KR101187625B1 (ko) * | 2004-09-10 | 2012-10-05 | 도쿠리츠다이가쿠호징 가나자와다이가쿠 | 경구 투여 백신 |
| JP4182074B2 (ja) * | 2005-03-03 | 2008-11-19 | ファナック株式会社 | ハンド及びハンドリングロボット |
| US20060240456A1 (en) * | 2005-03-22 | 2006-10-26 | Liaohai Chen | Nanosized biological container and manufacture thereof |
| AR054259A1 (es) * | 2005-04-26 | 2007-06-13 | Glaxosmithkline Biolog Sa | Vacuna contra virus de papiloma humano (hpv) |
| JP2008539182A (ja) * | 2005-04-26 | 2008-11-13 | グラクソスミスクライン バイオロジカルズ ソシエテ アノニム | ワクチン |
| AU2006295040A1 (en) * | 2005-09-08 | 2007-04-05 | Kentucky Bioprocessing, Llc | Modified tobacco mosaic virus particles as scaffolds for display of protein antigens for vaccine applications |
| US8450056B2 (en) | 2008-05-02 | 2013-05-28 | University Of Rochester | Arrayed imaging reflectometry (AIR) sensor chip comprising virus-like particles suitable for the detection of antiviral immune responses |
| WO2010125201A1 (en) | 2009-05-01 | 2010-11-04 | Redbiotec Ag | Recombinant virus-like particles encoded by multi-gene vector |
| CN114174320B (zh) * | 2019-07-19 | 2024-05-24 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒18型l1蛋白 |
| CN114127127B (zh) * | 2019-07-19 | 2024-04-09 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒35型l1蛋白 |
| WO2021013063A1 (zh) * | 2019-07-19 | 2021-01-28 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒16型l1蛋白 |
| AU2020317321B2 (en) * | 2019-07-19 | 2023-07-27 | Sinocelltech Ltd. | Polyvalent immunogenicity composition for human papillomavirus |
| CN114127100B (zh) * | 2019-07-19 | 2024-04-02 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒39型l1蛋白 |
| CA3147850A1 (en) * | 2019-07-19 | 2021-01-28 | Sinocelltech Ltd. | Chimeric papillomavirus l1 protein |
| WO2021013069A1 (zh) * | 2019-07-19 | 2021-01-28 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒11型l1蛋白 |
| CN114127093B (zh) * | 2019-07-19 | 2024-04-12 | 神州细胞工程有限公司 | 嵌合的人乳头瘤病毒45型l1蛋白 |
| CN110646612A (zh) * | 2019-09-30 | 2020-01-03 | 源道隆（苏州）医学科技有限公司 | 一种用于检测血清hpv抗体的试剂及试剂盒 |
| TWI858159B (zh) * | 2020-10-13 | 2024-10-11 | 大陸商神州細胞工程有限公司 | 人乳頭瘤病毒多價免疫原性組合物 |
| PH12023551919A1 (en) * | 2021-01-14 | 2023-12-04 | Sinocelltech Ltd | Stable preparation of human papillomavirus virus-like particle vaccine |
| CN117737311B (zh) * | 2024-02-20 | 2024-04-19 | 湖南派智生物科技有限公司 | 检测犬乳头瘤病毒的通用引物对、试剂、试剂盒及应用 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5618536A (en) | 1992-09-03 | 1997-04-08 | The United States Of America As Represented By The Department Of Health And Human Services | Chimeric papillomavirus-like particles |
| DE59511047D1 (de) | 1994-10-07 | 2006-06-14 | Univ Loyola Chicago | Papillomavirusähnliche partikel, fusionsproteine sowie verfahren zu deren herstellung |
| WO1997004076A1 (en) * | 1995-07-19 | 1997-02-06 | Merck & Co., Inc. | Synthetic hpv11 virus-like particles |
| AUPO390396A0 (en) * | 1996-11-29 | 1996-12-19 | Csl Limited | Novel promiscuous T helper cell epitopes |
| FR2767217B1 (fr) * | 1997-08-06 | 1999-11-12 | Conception Organisation Logist | Systeme de lecture et d'authentification d'un code magnetique |
| US6228368B1 (en) * | 1997-10-06 | 2001-05-08 | Loyola University Of Chicago | Papilloma virus capsomere formulations and method of use |
| DE69930960T2 (de) * | 1998-12-17 | 2007-04-19 | Merck & Co., Inc. | Synthetische virus-ähnliche partikel mit heterologen epitopen. |
| US6908613B2 (en) * | 2000-06-21 | 2005-06-21 | Medimmune, Inc. | Chimeric human papillomavirus (HPV) L1 molecules and uses therefor |
-
2001
- 2001-06-08 US US09/876,256 patent/US6908613B2/en not_active Expired - Lifetime
- 2001-06-12 WO PCT/US2001/018774 patent/WO2001097840A1/en active IP Right Grant
- 2001-06-12 AU AU2001275458A patent/AU2001275458B2/en not_active Expired
- 2001-06-12 AT AT01942170T patent/ATE386105T1/de active
- 2001-06-12 DK DK01942170T patent/DK1292328T3/da active
- 2001-06-12 EP EP01942170A patent/EP1292328B1/de not_active Expired - Lifetime
- 2001-06-12 PT PT01942170T patent/PT1292328E/pt unknown
- 2001-06-12 AU AU7545801A patent/AU7545801A/xx active Pending
- 2001-06-12 ES ES01942170T patent/ES2301551T3/es not_active Expired - Lifetime
- 2001-06-12 CA CA2411945A patent/CA2411945C/en not_active Expired - Lifetime
- 2001-06-12 DE DE60132770T patent/DE60132770T2/de not_active Expired - Lifetime
-
2005
- 2005-06-16 US US11/154,791 patent/US7390487B2/en not_active Expired - Lifetime
-
2008
- 2008-05-06 CY CY20081100480T patent/CY1108106T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE60132770D1 (de) | 2008-03-27 |
| US20040224305A1 (en) | 2004-11-11 |
| CA2411945C (en) | 2015-05-26 |
| AU2001275458B2 (en) | 2004-08-19 |
| AU7545801A (en) | 2002-01-02 |
| WO2001097840A1 (en) | 2001-12-27 |
| EP1292328A1 (de) | 2003-03-19 |
| US7390487B2 (en) | 2008-06-24 |
| CA2411945A1 (en) | 2001-12-27 |
| CY1108106T1 (el) | 2014-02-12 |
| DK1292328T3 (da) | 2008-06-16 |
| DE60132770T2 (de) | 2009-05-07 |
| US6908613B2 (en) | 2005-06-21 |
| ES2301551T3 (es) | 2008-07-01 |
| EP1292328A4 (de) | 2005-01-26 |
| EP1292328B1 (de) | 2008-02-13 |
| US20060127979A1 (en) | 2006-06-15 |
| PT1292328E (pt) | 2008-05-19 |
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| Date | Code | Title | Description |
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