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ATE374034T1 - Konditioniertes medium und diffusionsfähiges biologisches material gewonnen durch inkubierung von eingeschlossenen zellen - Google Patents

Konditioniertes medium und diffusionsfähiges biologisches material gewonnen durch inkubierung von eingeschlossenen zellen

Info

Publication number
ATE374034T1
ATE374034T1 AT03018701T AT03018701T ATE374034T1 AT E374034 T1 ATE374034 T1 AT E374034T1 AT 03018701 T AT03018701 T AT 03018701T AT 03018701 T AT03018701 T AT 03018701T AT E374034 T1 ATE374034 T1 AT E374034T1
Authority
AT
Austria
Prior art keywords
conditioned medium
encapled
diffusive
incubation
cells
Prior art date
Application number
AT03018701T
Other languages
English (en)
Inventor
Kanti Jain
Albert Rubin
Shirin Asina
Barry Smith
Kurt Stenzal
Original Assignee
Rogosin Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/745,063 external-priority patent/US5888497A/en
Application filed by Rogosin Inst filed Critical Rogosin Inst
Application granted granted Critical
Publication of ATE374034T1 publication Critical patent/ATE374034T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/22—Urine; Urinary tract, e.g. kidney or bladder; Intraglomerular mesangial cells; Renal mesenchymal cells; Adrenal gland
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/126—Immunoprotecting barriers, e.g. jackets, diffusion chambers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Dispersion Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicinal Preparation (AREA)
AT03018701T 1996-04-03 1997-03-21 Konditioniertes medium und diffusionsfähiges biologisches material gewonnen durch inkubierung von eingeschlossenen zellen ATE374034T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62559596A 1996-04-03 1996-04-03
US08/745,063 US5888497A (en) 1996-04-03 1996-11-07 Agarose coated agarose beads containing cancer cells that produce material which suppresses cancer cell proliferation

Publications (1)

Publication Number Publication Date
ATE374034T1 true ATE374034T1 (de) 2007-10-15

Family

ID=27089961

Family Applications (2)

Application Number Title Priority Date Filing Date
AT97915180T ATE250858T1 (de) 1996-04-03 1997-03-21 Implantierbare agarose-kollagenkügelchen enthaltende zellen, die ein diffusionsfähiges biologisches produkt bilden und ihre verwendung
AT03018701T ATE374034T1 (de) 1996-04-03 1997-03-21 Konditioniertes medium und diffusionsfähiges biologisches material gewonnen durch inkubierung von eingeschlossenen zellen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT97915180T ATE250858T1 (de) 1996-04-03 1997-03-21 Implantierbare agarose-kollagenkügelchen enthaltende zellen, die ein diffusionsfähiges biologisches produkt bilden und ihre verwendung

Country Status (16)

Country Link
EP (2) EP1382346B1 (de)
JP (2) JP3765039B2 (de)
CN (2) CN1296477C (de)
AT (2) ATE250858T1 (de)
AU (1) AU722109C (de)
CA (1) CA2250880C (de)
DE (2) DE69725317T2 (de)
DK (2) DK0914043T3 (de)
ES (2) ES2290390T3 (de)
FI (1) FI120332B (de)
HK (2) HK1019037A1 (de)
IL (1) IL126442A0 (de)
NO (1) NO320334B1 (de)
NZ (2) NZ331960A (de)
PT (1) PT914043E (de)
WO (1) WO1997036495A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7297331B2 (en) 1996-04-03 2007-11-20 The Rogosin Institute Beads containing restricted cancer cells producing material suppressing cancer cell proliferation
US6303151B1 (en) * 1996-04-03 2001-10-16 The Rogosin Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
US6224912B1 (en) * 1996-04-03 2001-05-01 The Rogo Institute Cancer-cell proliferation-suppressing material produced by cancer cells restricted by entrapment
NO983911D0 (no) 1998-08-26 1998-08-26 Norsk Hydro As Alginatkapsler til bruk ved behandling av hjernesvulst
AU2003264652B2 (en) * 1998-11-09 2006-09-14 The Rogosin Institute Compositions of restricted cells capable of rapid growth which produce proliferation suppressive materials, and uses thereof
US8257715B1 (en) 2004-08-26 2012-09-04 University Of Notre Dame Tissue vaccines and uses thereof
US8778360B2 (en) * 2005-10-27 2014-07-15 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US8778362B2 (en) 2005-10-27 2014-07-15 University Of Notre Dame Anti-tumor/cancer heterologous acellular collagenous preparations and uses thereof
US9308252B2 (en) 2005-10-27 2016-04-12 Cook Biotech, Inc. Extracellular matrix materials as vaccine adjuvants for diseases associated with infectious pathogens or toxins
US8802113B2 (en) 2005-10-27 2014-08-12 University Of Notre Dame Extracellular matrix cancer vaccine adjuvant
US9283266B2 (en) 2008-02-28 2016-03-15 University Of Notre Dame Metastasis inhibition preparations and methods
US8846059B2 (en) 2009-12-08 2014-09-30 University Of Notre Dame Extracellular matrix adjuvant and methods for prevention and/or inhibition of ovarian tumors and ovarian cancer
NZ624195A (en) * 2012-01-31 2015-07-31 Rogosin Inst Improved method for manufacture of macrobeads
EP3746785A4 (de) 2018-02-02 2022-05-11 Wake Forest University Health Sciences, Inc. Mit einer immuntherapie verwandte organoide und verfahren zur herstellung und verwendung davon

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE441009B (sv) * 1982-03-08 1985-09-02 Kjell Nilsson Sett att immobilisera levande biomaterial i perlformiga polymerer
US4798786A (en) * 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
CA1196862A (en) * 1983-06-01 1985-11-19 Anthony M.F. Sun Microencapsulation of living tissue and cells
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
SE8604684L (sv) * 1986-11-03 1988-05-04 Excorim Kommanditbolag Sett att belegga fasta partiklar med en hydrofil gel samt genom settet belagda partiklar
JP2691557B2 (ja) * 1988-04-15 1997-12-17 興研株式会社 人の悪性腫瘍細胞増殖抑制剤
US5053332A (en) * 1989-07-24 1991-10-01 Cook Richard B Agarose beads, preferably incorporating biological materials
US5241051A (en) * 1992-04-24 1993-08-31 Research Development Foundation Oncoinhibin
NZ329619A (en) * 1994-01-13 1999-09-29 Rogosin Inst Use of macroencapsulated secretory cells in agarose coated collagen gel material to treat diseases related to secretory cell failure
US5651980A (en) * 1994-04-15 1997-07-29 Biohybrid Technologies, Inc. Methods of use of uncoated gel particles

Also Published As

Publication number Publication date
EP0914043A4 (de) 2001-08-29
FI120332B (fi) 2009-09-30
CN1296477C (zh) 2007-01-24
CN1215309A (zh) 1999-04-28
ES2206696T3 (es) 2004-05-16
EP0914043B1 (de) 2003-10-01
AU722109B2 (en) 2000-07-20
CN1495253A (zh) 2004-05-12
IL126442A0 (en) 1999-08-17
AU2218897A (en) 1997-10-22
NZ337109A (en) 2004-12-24
NO984627L (no) 1998-11-30
CA2250880C (en) 2008-01-15
CN1119080C (zh) 2003-08-27
DE69725317T2 (de) 2004-07-29
JP2001503380A (ja) 2001-03-13
NO984627D0 (no) 1998-10-02
FI981957L (fi) 1998-12-02
AU722109C (en) 2001-07-19
ATE250858T1 (de) 2003-10-15
DE69738170D1 (de) 2007-11-08
JP4480152B2 (ja) 2010-06-16
DE69725317D1 (de) 2003-11-06
PT914043E (pt) 2004-02-27
NZ331960A (en) 1999-10-28
DE69738170T2 (de) 2008-01-24
HK1019037A1 (en) 2000-01-21
NO320334B1 (no) 2005-11-21
EP1382346B1 (de) 2007-09-26
DK0914043T3 (da) 2004-02-09
FI981957A0 (fi) 1998-09-11
HK1066026A1 (en) 2005-03-11
JP2005104987A (ja) 2005-04-21
ES2290390T3 (es) 2008-02-16
EP1382346A1 (de) 2004-01-21
JP3765039B2 (ja) 2006-04-12
CA2250880A1 (en) 1997-10-09
EP0914043A1 (de) 1999-05-12
DK1382346T3 (da) 2008-01-28
WO1997036495A1 (en) 1997-10-09

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