ATE370140T1 - Kondensierte bicyclische pyrimidinderivate - Google Patents
Kondensierte bicyclische pyrimidinderivateInfo
- Publication number
- ATE370140T1 ATE370140T1 AT03712828T AT03712828T ATE370140T1 AT E370140 T1 ATE370140 T1 AT E370140T1 AT 03712828 T AT03712828 T AT 03712828T AT 03712828 T AT03712828 T AT 03712828T AT E370140 T1 ATE370140 T1 AT E370140T1
- Authority
- AT
- Austria
- Prior art keywords
- ring
- bicyclic pyrimidine
- pyrimidine derivatives
- condensed bicyclic
- receptor antagonist
- Prior art date
Links
- CZPWVGJYEJSRLH-UHFFFAOYSA-N Pyrimidine Chemical class C1=CN=CN=C1 CZPWVGJYEJSRLH-UHFFFAOYSA-N 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 abstract 1
- 102000002002 Neurokinin-1 Receptors Human genes 0.000 abstract 1
- 108010040718 Neurokinin-1 Receptors Proteins 0.000 abstract 1
- 125000004448 alkyl carbonyl group Chemical group 0.000 abstract 1
- 125000004390 alkyl sulfonyl group Chemical group 0.000 abstract 1
- -1 bicyclic pyrimidine derivative Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 239000002464 receptor antagonist Substances 0.000 abstract 1
- 229940044551 receptor antagonist Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000001424 substituent group Chemical group 0.000 abstract 1
- 239000002462 tachykinin receptor antagonist Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/14—Antitussive agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/10—Drugs for disorders of the urinary system of the bladder
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Immunology (AREA)
- Rheumatology (AREA)
- Otolaryngology (AREA)
- Physical Education & Sports Medicine (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002084759 | 2002-03-26 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE370140T1 true ATE370140T1 (de) | 2007-09-15 |
Family
ID=28449223
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03712828T ATE370140T1 (de) | 2002-03-26 | 2003-03-24 | Kondensierte bicyclische pyrimidinderivate |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US7064119B2 (de) |
| EP (1) | EP1496059B1 (de) |
| JP (1) | JP4402959B2 (de) |
| KR (1) | KR20040093182A (de) |
| CN (1) | CN1330654C (de) |
| AT (1) | ATE370140T1 (de) |
| AU (1) | AU2003221205B2 (de) |
| BR (1) | BR0308844A (de) |
| CA (1) | CA2479277A1 (de) |
| DE (1) | DE60315626T2 (de) |
| DK (1) | DK1496059T3 (de) |
| MX (1) | MXPA04009300A (de) |
| NO (1) | NO20044331L (de) |
| NZ (1) | NZ535183A (de) |
| PT (1) | PT1496059E (de) |
| WO (1) | WO2003080619A1 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007509184A (ja) * | 2003-10-27 | 2007-04-12 | ノバルティス アクチエンゲゼルシャフト | 尿失禁の処置におけるニューロキニンアンタゴニストの使用 |
| US8102868B2 (en) * | 2006-01-05 | 2012-01-24 | Folusha Forte B.V., Llc | Interleaved and directional wireless mesh network |
| US20070297366A1 (en) * | 2006-01-05 | 2007-12-27 | Robert Osann | Synchronized wireless mesh network |
| US20070183439A1 (en) * | 2006-01-05 | 2007-08-09 | Osann Robert Jr | Combined directional and mobile interleaved wireless mesh network |
| TW200914457A (en) * | 2007-05-31 | 2009-04-01 | Kyowa Hakko Kogyo Kk | Pyrimidodiazepinone derivative |
| CN115368363B (zh) * | 2021-05-17 | 2024-02-20 | 中山大学 | 一种手性或消旋的嘧啶并二氮杂环庚酮类化合物及其制备方法和应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5770590A (en) | 1995-03-24 | 1998-06-23 | Takeda Chemical Industries, Ltd. | Cyclic compounds, their prudiction and use |
| JP2976097B2 (ja) * | 1995-03-24 | 1999-11-10 | 武田薬品工業株式会社 | 環状化合物、その製造法および剤 |
| JP3993264B2 (ja) | 1995-03-24 | 2007-10-17 | 武田薬品工業株式会社 | 環状化合物、その製造法および剤 |
| JP2002348289A (ja) | 2001-03-19 | 2002-12-04 | Takeda Chem Ind Ltd | ３環性複素環化合物、その製造法および用途 |
-
2003
- 2003-03-24 BR BR0308844-8A patent/BR0308844A/pt not_active IP Right Cessation
- 2003-03-24 CN CNB038120410A patent/CN1330654C/zh not_active Expired - Fee Related
- 2003-03-24 DK DK03712828T patent/DK1496059T3/da active
- 2003-03-24 EP EP03712828A patent/EP1496059B1/de not_active Expired - Lifetime
- 2003-03-24 WO PCT/JP2003/003488 patent/WO2003080619A1/ja not_active Ceased
- 2003-03-24 NZ NZ535183A patent/NZ535183A/xx unknown
- 2003-03-24 JP JP2003578373A patent/JP4402959B2/ja not_active Expired - Fee Related
- 2003-03-24 PT PT03712828T patent/PT1496059E/pt unknown
- 2003-03-24 AU AU2003221205A patent/AU2003221205B2/en not_active Ceased
- 2003-03-24 AT AT03712828T patent/ATE370140T1/de not_active IP Right Cessation
- 2003-03-24 US US10/509,224 patent/US7064119B2/en not_active Expired - Fee Related
- 2003-03-24 KR KR10-2004-7015036A patent/KR20040093182A/ko not_active Ceased
- 2003-03-24 DE DE60315626T patent/DE60315626T2/de not_active Expired - Fee Related
- 2003-03-24 CA CA002479277A patent/CA2479277A1/en not_active Abandoned
- 2003-03-24 MX MXPA04009300A patent/MXPA04009300A/es active IP Right Grant
-
2004
- 2004-10-12 NO NO20044331A patent/NO20044331L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| EP1496059B1 (de) | 2007-08-15 |
| US20050159409A1 (en) | 2005-07-21 |
| CN1656098A (zh) | 2005-08-17 |
| WO2003080619A1 (en) | 2003-10-02 |
| KR20040093182A (ko) | 2004-11-04 |
| US7064119B2 (en) | 2006-06-20 |
| PT1496059E (pt) | 2007-10-29 |
| CA2479277A1 (en) | 2003-10-02 |
| JPWO2003080619A1 (ja) | 2005-07-21 |
| CN1330654C (zh) | 2007-08-08 |
| AU2003221205B2 (en) | 2008-09-18 |
| AU2003221205A1 (en) | 2003-10-08 |
| EP1496059A1 (de) | 2005-01-12 |
| NO20044331L (no) | 2004-10-25 |
| NZ535183A (en) | 2006-03-31 |
| BR0308844A (pt) | 2005-01-04 |
| DE60315626T2 (de) | 2008-06-05 |
| JP4402959B2 (ja) | 2010-01-20 |
| MXPA04009300A (es) | 2005-01-25 |
| DK1496059T3 (da) | 2007-12-03 |
| EP1496059A4 (de) | 2006-02-08 |
| DE60315626D1 (de) | 2007-09-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |