[go: up one dir, main page]

ATE366814T1 - Gl50 moleküle, sowie verwendungen derselben - Google Patents

Gl50 moleküle, sowie verwendungen derselben

Info

Publication number
ATE366814T1
ATE366814T1 AT00965251T AT00965251T ATE366814T1 AT E366814 T1 ATE366814 T1 AT E366814T1 AT 00965251 T AT00965251 T AT 00965251T AT 00965251 T AT00965251 T AT 00965251T AT E366814 T1 ATE366814 T1 AT E366814T1
Authority
AT
Austria
Prior art keywords
nucleic acid
acid molecules
polypeptides
expression vectors
molecules
Prior art date
Application number
AT00965251T
Other languages
English (en)
Inventor
Vincent Ling
Kyriaki Dunussi-Joannopolulos
Original Assignee
Genetics Inst Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genetics Inst Llc filed Critical Genetics Inst Llc
Application granted granted Critical
Publication of ATE366814T1 publication Critical patent/ATE366814T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00965251T 1999-09-21 2000-09-21 Gl50 moleküle, sowie verwendungen derselben ATE366814T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15504399P 1999-09-21 1999-09-21

Publications (1)

Publication Number Publication Date
ATE366814T1 true ATE366814T1 (de) 2007-08-15

Family

ID=22553907

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00965251T ATE366814T1 (de) 1999-09-21 2000-09-21 Gl50 moleküle, sowie verwendungen derselben

Country Status (10)

Country Link
US (4) US6521749B1 (de)
EP (1) EP1218504B1 (de)
JP (1) JP4737905B2 (de)
AT (1) ATE366814T1 (de)
AU (1) AU7599500A (de)
DE (1) DE60035517T2 (de)
DK (1) DK1218504T3 (de)
ES (1) ES2290052T3 (de)
PT (1) PT1218504E (de)
WO (1) WO2001021796A2 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7112655B1 (en) 1997-02-27 2006-09-26 Japan Tobacco, Inc. JTT-1 protein and methods of inhibiting lymphocyte activation
JP3521382B2 (ja) 1997-02-27 2004-04-19 日本たばこ産業株式会社 細胞間接着及びシグナル伝達を媒介する細胞表面分子
US7435796B1 (en) 1999-02-03 2008-10-14 Amgen Inc. Antibodies which bind B7RP1
US7708993B2 (en) * 1999-02-03 2010-05-04 Amgen Inc. Polypeptides involved in immune response
US8624010B1 (en) 1999-02-03 2014-01-07 Steven K. Yoshinaga Nucleic acids encoding B7RP1
AU773954B2 (en) * 1999-02-03 2004-06-10 Amgen, Inc. Novel Polypeptides involved in immune response
JP3871503B2 (ja) 1999-08-30 2007-01-24 日本たばこ産業株式会社 免疫性疾患治療剤
JP4210454B2 (ja) 2001-03-27 2009-01-21 日本たばこ産業株式会社 炎症性腸疾患治療剤
JP3597140B2 (ja) 2000-05-18 2004-12-02 日本たばこ産業株式会社 副刺激伝達分子ａｉｌｉｍに対するヒトモノクローナル抗体及びその医薬用途
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
AU2002242175A1 (en) * 2001-02-16 2002-09-04 Brigham And Women's Hospital Methods for modulating an immune response by modulating the interaction between ctla4 and pp2a
JP4212278B2 (ja) 2001-03-01 2009-01-21 日本たばこ産業株式会社 移植片拒絶反応抑制剤
US7235631B2 (en) * 2002-02-07 2007-06-26 Mayo Foundation For Medical Education And Research ICOS mutants
US20040102398A1 (en) * 2002-11-23 2004-05-27 Isis Pharmaceuticals Inc. Modulation of B7H expression
AT500650B1 (de) 2003-04-17 2009-11-15 Altropus Gmbh Immunogener rekombinanter antikörper
SG196835A1 (en) 2005-07-18 2014-02-13 Amgen Inc Human anti-b7rp1 neutralizing antibodies
ES2651946T3 (es) 2008-06-30 2018-01-30 Institut National De La Sante Et De La Recherche Medicale Utilización de péptidos CD31 en el tratamiento de trastornos trombóticos y autoinmunes
AU2010282340B2 (en) * 2009-08-13 2016-12-22 The Johns Hopkins University Methods of modulating immune function
EP3375791A1 (de) 2009-09-30 2018-09-19 Memorial Sloan Kettering Cancer Center Kombinationsimmuntherapie zur behandlung von krebs
WO2011097477A1 (en) * 2010-02-04 2011-08-11 The Trustees Of The University Of Pennsylvania Icos critically regulates the expansion and function of inflammatory human th17 cells
CN102675470B (zh) * 2012-04-01 2015-06-17 江苏省弗泰生物科技有限公司 SCF-Fc融合蛋白
US9458246B2 (en) 2013-03-13 2016-10-04 Amgen Inc. Proteins specific for BAFF and B7RP1
PH12022550138A1 (en) 2013-03-13 2023-03-06 Amgen Inc Proteins specific for baff and b7rp1 and uses thereof
CN104232667A (zh) * 2014-09-16 2014-12-24 宁夏医科大学 FcRn介导的抗细粒棘球蚴靶向黏膜疫苗载体的构建方法
MA53297A (fr) 2015-03-23 2022-05-04 Jounce Therapeutics Inc Anticorps anti-icos
EP3875477A1 (de) 2015-04-17 2021-09-08 Alpine Immune Sciences, Inc. Immunmodulatorische proteine mit einstellbaren affinitäten
JP2018534927A (ja) 2015-10-22 2018-11-29 ジョンス セラピューティクス， インコーポレイテッド Ｉｃｏｓ発現を決定する遺伝子シグネチャー
SG10201912046VA (en) * 2016-02-26 2020-02-27 Scm Lifescience Co Ltd Pharmaceutical composition for preventing or treating regulatory t cell-mediated diseases
KR20230051601A (ko) 2016-04-15 2023-04-18 알파인 이뮨 사이언시즈, 인코포레이티드 Icos 리간드 변이체 면역조절 단백질 및 그의 용도
US11753458B2 (en) 2017-10-10 2023-09-12 Alpine Immune Sciences, Inc. CTLA-4 variant immunomodulatory proteins and uses thereof
CA3078517A1 (en) 2017-10-18 2019-04-25 Alpine Immune Sciences, Inc. Variant icos ligand immunomodulatory proteins and related compositions and methods
WO2019178113A1 (en) * 2018-03-12 2019-09-19 Board Of Regents, The University Of Texas System Immuno-exosomes and methods of use thereof
EP3860653A1 (de) 2018-10-05 2021-08-11 INSERM (Institut National de la Santé et de la Recherche Médicale) Verfahren und systeme zur steuerung der agonistischen eigenschaften von variablen antikörperdomänen durch licht
KR20220088752A (ko) 2019-10-28 2022-06-28 메드임뮨 리미티드 흉선 기질 림포포이에틴 (tslp)-결합 항체들의 건조 분말 제형 및 이의 사용 방법
EP4507779A1 (de) 2022-04-14 2025-02-19 Institut National de la Santé et de la Recherche Médicale Verfahren zur kontrolle der tumorzellabtötung durch licht

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4837306A (en) 1985-02-25 1989-06-06 The Ontario Cancer Institute Method for selecting hybridomas producing antibodies specific to the P-glycoprotein cell suface antigen and a cDNA clone encoding the C-terminal portion of the antigen
US5580756A (en) 1990-03-26 1996-12-03 Bristol-Myers Squibb Co. B7Ig fusion protein
US6130316A (en) * 1993-07-26 2000-10-10 Dana Farber Cancer Institute Fusion proteins of novel CTLA4/CD28 ligands and uses therefore
JP3521382B2 (ja) 1997-02-27 2004-04-19 日本たばこ産業株式会社 細胞間接着及びシグナル伝達を媒介する細胞表面分子
WO1999015553A2 (de) 1997-09-23 1999-04-01 Bundesrepublik Deutschland Letztvertreten Durch Den Direktor Des Robert-Koch-Instituts Ko-stimulierendes polypeptid von t-zellen, monoklonale antikörper sowie die herstellung und deren verwendung
AU773954B2 (en) * 1999-02-03 2004-06-10 Amgen, Inc. Novel Polypeptides involved in immune response

Also Published As

Publication number Publication date
JP2003510047A (ja) 2003-03-18
US20100055091A1 (en) 2010-03-04
EP1218504B1 (de) 2007-07-11
AU7599500A (en) 2001-04-24
US20040054158A1 (en) 2004-03-18
ES2290052T3 (es) 2008-02-16
US7521532B2 (en) 2009-04-21
JP4737905B2 (ja) 2011-08-03
DE60035517D1 (de) 2007-08-23
PT1218504E (pt) 2007-10-22
WO2001021796A3 (en) 2001-08-09
DK1218504T3 (da) 2007-11-12
US7976840B2 (en) 2011-07-12
WO2001021796A2 (en) 2001-03-29
DE60035517T2 (de) 2008-03-20
US20060099635A1 (en) 2006-05-11
WO2001021796A9 (en) 2002-12-05
US6521749B1 (en) 2003-02-18
EP1218504A2 (de) 2002-07-03
US7601813B2 (en) 2009-10-13

Similar Documents

Publication Publication Date Title
FR19C1020I1 (fr) Nouvelles molecules b7-4 et leurs utilisations
ATE366814T1 (de) Gl50 moleküle, sowie verwendungen derselben
WO2003042362A3 (en) PGC-1β, A NOVEL PGC-1 HOMOLOGUE AND USES THEREFOR
EP1412374A4 (de) Neue pgc-1-isoformen und deren verwendungen
WO2002016591A3 (en) Human transporter family members and uses thereof
AU2001280639A1 (en) 13237,18480,2245 or 16228 human protein kinase molecules and uses therefor
EP1900816A3 (de) GL50-Moleküle und Verwendungen davon
WO2001066764A3 (en) 16835, a human phospholipase c and uses thereof
WO2001090146A3 (en) 57256 and 58289, human transporters and uses thereof
DE60124910D1 (de) Menschliche twik-8 moleküle und ihre verwendung
WO2001074854A3 (en) 32449, a putative human transporter and uses thereof
DE60234047D1 (de) 15603, ein mitglied der humanen ionenkanal-familie
WO2001079293A3 (en) Human cadherin molecules and uses therefor
AU2002352068A1 (en) 2150, a human protein kinase family member and uses therefor
WO2001079497A3 (en) 33556, a human transporter and uses thereof
WO2002008397A3 (en) A human atpase and uses therefor
WO2002026802A3 (en) M32404, a novel human trypsin and uses thereof
WO2001081559A3 (en) 26335, a novel human serine/threonine dehydratase and uses thereof
WO2003042371A3 (en) 55053, a novel human eukaryotic kinase and uses therefor
WO2003091448A3 (en) 696803, a human transporter family member and uses therefor
DK1297151T3 (da) Nye 14911-proteinkinasemolekyler og anvendelser deraf
WO2002006465A3 (en) 7677, a novel human atpase family member and uses therefor
WO2002018577A3 (en) 48921, a novel human gtp releasing factor and uses therefor
WO2002057292A3 (en) 15569, a novel human g protein coupled receptor and uses therefor
WO2002000861A3 (en) Human beta-ketoacyl synthase (46619) and uses thereof

Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee