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ATE361745T1 - Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen - Google Patents

Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen

Info

Publication number
ATE361745T1
ATE361745T1 AT02714977T AT02714977T ATE361745T1 AT E361745 T1 ATE361745 T1 AT E361745T1 AT 02714977 T AT02714977 T AT 02714977T AT 02714977 T AT02714977 T AT 02714977T AT E361745 T1 ATE361745 T1 AT E361745T1
Authority
AT
Austria
Prior art keywords
carbamat
compounds
preventing
neurodegenerative disorders
treating neurodegenerative
Prior art date
Application number
AT02714977T
Other languages
English (en)
Inventor
Carlos R Plata-Salaman
Boyu Zhao
Roy E Twyman
Original Assignee
Ortho Mcneil Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Mcneil Pharm Inc filed Critical Ortho Mcneil Pharm Inc
Application granted granted Critical
Publication of ATE361745T1 publication Critical patent/ATE361745T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/325Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Emergency Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT02714977T 2001-02-27 2002-02-21 Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen ATE361745T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27168201P 2001-02-27 2001-02-27
US10/081,764 US20020165273A1 (en) 2001-02-27 2002-02-21 Carbamate compounds for use in preventing or treating neurodegenerative disorders

Publications (1)

Publication Number Publication Date
ATE361745T1 true ATE361745T1 (de) 2007-06-15

Family

ID=26765943

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02714977T ATE361745T1 (de) 2001-02-27 2002-02-21 Carbamatverbindungen zur vorbeugung oder behandlung von neurodegenerativen störungen

Country Status (27)

Country Link
US (3) US20020165273A1 (de)
EP (1) EP1383489B1 (de)
JP (1) JP4276840B2 (de)
KR (1) KR100910928B1 (de)
CN (1) CN1235579C (de)
AR (1) AR035756A1 (de)
AT (1) ATE361745T1 (de)
BR (1) BR0207645A (de)
CA (1) CA2439295C (de)
CY (1) CY1106753T1 (de)
CZ (1) CZ301203B6 (de)
DE (1) DE60220043T2 (de)
DK (1) DK1383489T3 (de)
ES (1) ES2284845T3 (de)
HK (2) HK1060516A1 (de)
HU (1) HUP0303264A3 (de)
IL (2) IL157591A0 (de)
MX (1) MXPA03007718A (de)
MY (1) MY138156A (de)
NO (1) NO20033798L (de)
NZ (1) NZ527990A (de)
PL (1) PL364680A1 (de)
PT (1) PT1383489E (de)
RS (1) RS51055B (de)
RU (1) RU2300373C2 (de)
TW (1) TWI312679B (de)
WO (1) WO2002067925A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2580584C (en) * 2003-09-19 2015-07-28 Galileo Pharmaceuticals, Inc. Use of alpha-tocotrienol for treatment of mitochondrial diseases
ATE464044T1 (de) * 2004-09-16 2010-04-15 Janssen Pharmaceutica Nv Verwendung von 2-phenyl-1,2-ethanediol- (di)carbamaten zur behandlung von epileptogenese
EA200700871A1 (ru) * 2004-10-15 2007-10-26 Янссен Фармацевтика Н. В. Способы нейропротекции
US20070021500A1 (en) * 2005-07-12 2007-01-25 Twyman Roy E Methods for neuroprotection
KR101199499B1 (ko) * 2005-07-26 2012-11-09 얀센 파마슈티카 엔.브이. 물질 관련 장애를 치료하는 방법
EA200970355A1 (ru) * 2006-10-06 2009-12-30 Янссен Фармацевтика Нв Новый кристалл (s)-(+)-2-(2-хлорфенил)-2-гидроксиэтилкарбамата
EP2081648A2 (de) * 2006-10-30 2009-07-29 Janssen Pharmaceutica, N.V. Carbamatverbindungen zur verwendung bei der behandlung von depressionen
EA200970435A1 (ru) * 2006-10-31 2009-10-30 Янссен Фармацевтика, Н. В. Лечение общих расстройств развития
BR112013000050B1 (pt) * 2010-07-02 2021-10-19 Bio-Pharm Solutions Co., Ltd Compostos de carbamato de fenila e composição farmacêutica
US9018253B2 (en) 2010-07-02 2015-04-28 Bio-Pharm Solutions Co., Ltd. Phenylcarbamate compound and muscle relaxant containing the same
US8609849B1 (en) 2010-11-30 2013-12-17 Fox Chase Chemical Diversity Center, Inc. Hydroxylated sulfamides exhibiting neuroprotective action and their method of use
WO2013036678A1 (en) * 2011-09-07 2013-03-14 Satori Pharmaceuticals, Inc. Compounds useful for treating neurodegenerative disorders
CA2858977C (en) * 2011-12-27 2020-06-23 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compounds for use in alleviating or treating pain
US9566261B2 (en) 2013-03-12 2017-02-14 Bio-Pharm Solutions Co., Ltd. Phenyl carbamate compound and a composition for preventing or treating a memory loss-related disease comprising the same
CN109939092B (zh) 2013-03-12 2022-03-22 比皮艾思药物研发有限公司 用于预防或治疗小儿癫痫和癫痫相关综合征的苯基氨基甲酸酯化合物
BR112018067663B1 (pt) * 2016-02-29 2023-01-10 Bio-Pharm Solutions Co., Ltd Compostos derivados de sulfamato, seus usos e composição farmacêutica
US11147798B2 (en) 2016-12-14 2021-10-19 Sk Biopharmaceuticals Co., Ltd. Use of carbamate compound for prevention, alleviation, or treatment of demyelinating disease
JP7408643B2 (ja) * 2018-09-21 2024-01-05 エスケー バイオファーマスティカルズ カンパニー リミテッド カルバメート化合物及びそれを含む製剤の急性ストレス障害又は心的外傷後ストレス障害の予防、軽減又は治療のための使用
EP4204395A4 (de) * 2020-08-31 2024-08-07 Bio-Pharm Solutions Co., Ltd. Phenylalkylcarbamatverbindungen zur verwendung bei der vorbeugung oder behandlung von neurodegenerativen erkrankungen
JP7648746B2 (ja) 2020-09-10 2025-03-18 バイオ-ファーム ソリューションズ カンパニー リミテッド 精神疾患の治療又は軽減のためのスルファメート誘導体化合物

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313692A (en) * 1958-04-21 1967-04-11 Armour Pharma Method of inducing calming and muscle relaxation with carbamates
US3278380A (en) * 1962-02-06 1966-10-11 Armour Pharma Methods of calming employing diphenyl hydroxy carbamate compounds
US3265728A (en) * 1962-07-18 1966-08-09 Armour Pharma Substituted phenethyl carbamates
US5474990A (en) * 1989-10-20 1995-12-12 Olney; John W. Barbiturates as safening agents in conjunction with NMDA antagonists
US5492930A (en) * 1994-04-25 1996-02-20 Schering Corporation Method and formulation for treating CNS disorders
US5698588A (en) * 1996-01-16 1997-12-16 Yukong Limited Halogen substituted carbamate compounds from 2-phenyl-1,2-ethanediol
US5728728A (en) * 1996-04-10 1998-03-17 Kozachuk; Walter E. Methods of providing neuroprotection
US6232434B1 (en) * 1996-08-02 2001-05-15 Duke University Medical Center Polymers for delivering nitric oxide in vivo
CZ302412B6 (cs) * 2001-02-27 2011-05-04 Ortho-Mcneil Pharmaceutical, Inc. Lécivo pro prevenci nebo lécbu psychotických chorob
CZ20032300A3 (cs) * 2001-02-27 2005-01-12 Ortho-Mcneil Pharmaceutical, Inc. Léčivo pro prevenci nebo léčbu bipolárních chorob
IL157592A0 (en) * 2001-02-27 2004-03-28 Ortho Mcneil Pharm Inc Carbamate compounds for use in preventing or treating movement disorders

Also Published As

Publication number Publication date
HUP0303264A2 (hu) 2004-01-28
KR100910928B1 (ko) 2009-08-06
CA2439295A1 (en) 2002-09-06
EP1383489B1 (de) 2007-05-09
CN1235579C (zh) 2006-01-11
JP2004523555A (ja) 2004-08-05
KR20030076714A (ko) 2003-09-26
RU2003128982A (ru) 2005-03-10
CN1503667A (zh) 2004-06-09
CA2439295C (en) 2010-05-25
JP4276840B2 (ja) 2009-06-10
US20040171679A1 (en) 2004-09-02
US20020165273A1 (en) 2002-11-07
WO2002067925A1 (en) 2002-09-06
BR0207645A (pt) 2004-12-28
HK1065486A1 (en) 2005-02-25
PL364680A1 (en) 2004-12-13
HK1060516A1 (en) 2004-08-13
CY1106753T1 (el) 2012-05-23
DK1383489T3 (da) 2007-08-06
RS51055B (sr) 2010-10-31
PT1383489E (pt) 2007-06-21
CZ301203B6 (cs) 2009-12-09
TWI312679B (en) 2009-08-01
NZ527990A (en) 2006-01-27
AR035756A1 (es) 2004-07-07
RU2300373C2 (ru) 2007-06-10
DE60220043D1 (de) 2007-06-21
DE60220043T2 (de) 2008-01-10
NO20033798L (no) 2003-09-26
US20090005442A1 (en) 2009-01-01
ES2284845T3 (es) 2007-11-16
NO20033798D0 (no) 2003-08-26
IL157591A0 (en) 2004-03-28
MXPA03007718A (es) 2004-11-12
MY138156A (en) 2009-04-30
EP1383489A1 (de) 2004-01-28
IL157591A (en) 2009-12-24
CZ20032313A3 (cs) 2004-08-18
HUP0303264A3 (en) 2012-07-30
RS67403A (en) 2006-12-15

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