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ATE359997T1 - Guanidinomethylcyclohexancarbonsäure-ester derivate - Google Patents

Guanidinomethylcyclohexancarbonsäure-ester derivate

Info

Publication number
ATE359997T1
ATE359997T1 AT04003617T AT04003617T ATE359997T1 AT E359997 T1 ATE359997 T1 AT E359997T1 AT 04003617 T AT04003617 T AT 04003617T AT 04003617 T AT04003617 T AT 04003617T AT E359997 T1 ATE359997 T1 AT E359997T1
Authority
AT
Austria
Prior art keywords
guanidinomethylcyclohexanecarbonic
acid ester
ester derivatives
present
helicobacter pylori
Prior art date
Application number
AT04003617T
Other languages
English (en)
Inventor
Osamu Kamoda
Hiromichi Fujiwara
Toshiharu Yanagi
Original Assignee
Nagase Chemtex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagase Chemtex Corp filed Critical Nagase Chemtex Corp
Application granted granted Critical
Publication of ATE359997T1 publication Critical patent/ATE359997T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/94—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of polycyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
AT04003617T 1994-08-30 1995-08-30 Guanidinomethylcyclohexancarbonsäure-ester derivate ATE359997T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP24348994 1994-08-30
JP24349094 1994-08-30
JP24827094 1994-09-05
JP25265594 1994-09-09

Publications (1)

Publication Number Publication Date
ATE359997T1 true ATE359997T1 (de) 2007-05-15

Family

ID=27477919

Family Applications (3)

Application Number Title Priority Date Filing Date
AT95930012T ATE197950T1 (de) 1994-08-30 1995-08-30 Guanidylmethyl cyclohexancarbonsäure ester derivate
AT04003617T ATE359997T1 (de) 1994-08-30 1995-08-30 Guanidinomethylcyclohexancarbonsäure-ester derivate
AT99124756T ATE264291T1 (de) 1994-08-30 1995-08-30 Zwischenprodukte für die herstellung von guanidinomethylcyclohexancarbonsäure-estern

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT95930012T ATE197950T1 (de) 1994-08-30 1995-08-30 Guanidylmethyl cyclohexancarbonsäure ester derivate

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT99124756T ATE264291T1 (de) 1994-08-30 1995-08-30 Zwischenprodukte für die herstellung von guanidinomethylcyclohexancarbonsäure-estern

Country Status (13)

Country Link
US (3) US6284791B1 (de)
EP (3) EP0775692B1 (de)
JP (1) JP3739011B2 (de)
KR (2) KR100404714B1 (de)
AT (3) ATE197950T1 (de)
DE (3) DE69535475T2 (de)
DK (3) DK0775692T3 (de)
ES (3) ES2153902T3 (de)
GR (1) GR3035289T3 (de)
HK (1) HK1027092A1 (de)
PT (3) PT775692E (de)
TW (1) TW408103B (de)
WO (1) WO1996006825A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020123508A1 (en) * 1995-12-22 2002-09-05 Osamu Kamoda Cyclohexane carbocyclic ester derivative and cyclodextrin complex and composition for treatment of helicobacter pylori infections
CN1203055C (zh) * 2001-09-26 2005-05-25 朱德煦 治疗或预防细菌感染的方法和组合物
WO2007105551A1 (ja) 2006-03-10 2007-09-20 Arigen Pharmaceuticals, Inc. 抗ヘリコバクター・ピロリ作用を有する新規ピリジン誘導体
MX2011010663A (es) 2009-04-09 2011-10-28 Arigen Pharmaceuticals Inc Derivado de piridina-tio, y composicion farmaceutica que contiene el mismo y tiene accion anti-helicobacter pylori.

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US2092724A (en) * 1936-08-20 1937-09-07 Dow Chemical Co Alkyl-chloro-hydroxy-diphenyls
US2092725A (en) * 1936-10-15 1937-09-07 Dow Chemical Co Alkyl-bromo-hydroxy-diphenyls
BE509380A (de) * 1950-02-23
AU541738B2 (en) * 1979-09-20 1985-01-17 Nippon Chemiphar Co. Ltd. Cyclohexane carboxylic acid derivatives
JPS5692260A (en) 1979-12-26 1981-07-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic ester and its preparation
JPS5645454A (en) 1979-09-20 1981-04-25 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid derivative and its preparation
JPS5692261A (en) * 1979-12-26 1981-07-25 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic derivative and its preparation
JPS5716856A (en) 1980-07-04 1982-01-28 Teikoku Chem Ind Corp Ltd 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
JPS5716855A (en) 1980-07-04 1982-01-28 Teikoku Chem Ind Corp Ltd 4-guanidinomethylcyclohexanecarboxylic acid ester and its preparation
JPS5721360A (en) 1980-07-14 1982-02-04 Teikoku Chem Ind Corp Ltd Allyl 4-guanidinomethylcyclohexanecarboxylate and its preparation
JPS5735556A (en) 1980-08-08 1982-02-26 Nippon Chemiphar Co Ltd Preparation of guanidinomethylcyclohexanecarboxylic acid ester
JPS5748958A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Cyclohexanecarboxylic acid esters and their acid addition salts
JPS5748960A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS5748959A (en) 1980-09-08 1982-03-20 Nippon Chemiphar Co Ltd Preparation of cyclohexanecarboxylic acid derivative or its salt
JPS5775922A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Novel remedy for peptic ulcer
JPS5775920A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Noval remedy for peptic ulcer
JPS5775921A (en) 1980-10-29 1982-05-12 Nippon Chemiphar Co Ltd Noval remedy for peptic ulcer
JPS57122059A (en) * 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS57122061A (en) * 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxylic acid derivative and its preparation
JPS57126463A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel carboxylic ester and its preparation
JPS57126462A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel carboxylic ester and its preparation
JPS57122060A (en) 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Carboxylic acid ester and its preparation
US4465851A (en) * 1981-01-22 1984-08-14 Nippon Chemiphar Co., Ltd. Guanidinocyclohexanecarboxylic acid derivatives
JPS57122062A (en) * 1981-01-22 1982-07-29 Nippon Chemiphar Co Ltd Novel trans-4-guanidinocyclohexanecarboxylic acid derivative and its preparation
JPS57126461A (en) 1981-01-29 1982-08-06 Nippon Chemiphar Co Ltd Novel guanidino compound and its preparation
JPS57197256A (en) 1981-05-28 1982-12-03 Nippon Chemiphar Co Ltd Novel cyclohexanecarboxamide derivative and its preparation
DE3685032D1 (de) * 1985-01-09 1992-06-04 Dainippon Ink & Chemicals Substituierte fluessigkristallverbindungen.
JPS6254A (ja) 1985-03-08 1987-01-06 Kanebo Ltd 新規グアニジノメチルシクロヘキサンカルボン酸誘導体および該化合物を有効成分とする抗潰瘍薬
US4798680A (en) * 1985-10-18 1989-01-17 Canon Kabushiki Kaisha Optically active compound, process for producing same and liquid crystal composition containing same
US4844835A (en) * 1985-12-26 1989-07-04 Idenitsu Kosan Co., Ltd. Ferroelectric liquid crystal polymer
JPS62187435A (ja) * 1986-02-13 1987-08-15 Asahi Chem Ind Co Ltd ヒドロキシ芳香族カルボン酸エステルの製造方法
JPS6330462A (ja) 1986-07-24 1988-02-09 Taiyo Yakuhin Kogyo Kk 新規グアニジノメチルベンツアミド誘導体およびそれを有効成分とする抗潰瘍剤
DE3778458D1 (de) * 1986-09-04 1992-05-27 Idemitsu Kosan Co Fluessigkristallpolymere.
JPS63218652A (ja) 1987-03-09 1988-09-12 Taiyo Yakuhin Kogyo Kk 新規グアニジノメチル安息香酸誘導体およびこれを含有する消化性潰瘍治療剤
JPH04217950A (ja) 1990-03-28 1992-08-07 Asahi Chem Ind Co Ltd ヒドロキサム酸誘導体および酵素阻害剤ならびに抗潰瘍剤
JP3073006B2 (ja) 1990-11-28 2000-08-07 株式会社日立製作所 聴覚機能補助装置
EP0585130B1 (de) 1992-08-27 1998-01-28 Shiseido Company Limited Äusserliche, auf der Haut anzuwendende Depigmentierungsmittel enthaltende Zusammensetzung
JP3150780B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3150781B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3150782B2 (ja) 1992-09-01 2001-03-26 株式会社資生堂 皮膚外用剤
JP3046288B1 (ja) 1998-12-28 2000-05-29 京セラ株式会社 半導体・液晶製造装置用部材
JP3555682B2 (ja) 2002-07-09 2004-08-18 セイコーエプソン株式会社 液体吐出ヘッド

Also Published As

Publication number Publication date
ATE264291T1 (de) 2004-04-15
ES2285288T3 (es) 2007-11-16
EP0775692A4 (de) 1997-12-17
US20050075402A1 (en) 2005-04-07
EP0775692B1 (de) 2000-12-06
DK0989112T3 (da) 2004-07-12
DE69519581D1 (de) 2001-01-11
PT775692E (pt) 2001-05-31
DE69532897T2 (de) 2005-04-21
US6831190B1 (en) 2004-12-14
KR100416066B1 (ko) 2004-01-24
EP0989112A3 (de) 2000-11-15
DK1449828T3 (da) 2007-08-06
ES2153902T3 (es) 2001-03-16
PT1449828E (pt) 2007-06-01
EP0775692A1 (de) 1997-05-28
EP1449828B1 (de) 2007-04-18
DE69519581T2 (de) 2001-05-31
TW408103B (en) 2000-10-11
PT989112E (pt) 2004-08-31
ES2214802T3 (es) 2004-09-16
KR970705540A (ko) 1997-10-09
KR100404714B1 (ko) 2004-05-31
WO1996006825A1 (fr) 1996-03-07
EP0989112B1 (de) 2004-04-14
DE69535475D1 (de) 2007-05-31
DE69535475T2 (de) 2008-01-03
HK1027092A1 (en) 2003-09-17
EP1449828A3 (de) 2004-12-22
DK0775692T3 (da) 2001-03-05
ATE197950T1 (de) 2000-12-15
GR3035289T3 (en) 2001-04-30
DE69532897D1 (de) 2004-05-19
JP3739011B2 (ja) 2006-01-25
US6960681B2 (en) 2005-11-01
US6284791B1 (en) 2001-09-04
EP1449828A2 (de) 2004-08-25
EP0989112A2 (de) 2000-03-29

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