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ATE347598T1 - Transformierte linie der hefe candida utilis und die dadurch möglich expression eines heterogens - Google Patents

Transformierte linie der hefe candida utilis und die dadurch möglich expression eines heterogens

Info

Publication number
ATE347598T1
ATE347598T1 AT95919636T AT95919636T ATE347598T1 AT E347598 T1 ATE347598 T1 AT E347598T1 AT 95919636 T AT95919636 T AT 95919636T AT 95919636 T AT95919636 T AT 95919636T AT E347598 T1 ATE347598 T1 AT E347598T1
Authority
AT
Austria
Prior art keywords
heterogene
candida utilis
transformed line
possible expression
resulting possible
Prior art date
Application number
AT95919636T
Other languages
English (en)
Inventor
Keiji Kondo
Susumu Kajiwara
Norihiko Misawa
Original Assignee
Kirin Brewery
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kirin Brewery filed Critical Kirin Brewery
Application granted granted Critical
Publication of ATE347598T1 publication Critical patent/ATE347598T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/40—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Candida
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT95919636T 1994-05-25 1995-05-25 Transformierte linie der hefe candida utilis und die dadurch möglich expression eines heterogens ATE347598T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP13501594 1994-05-25
JP28582394 1994-10-26
JP7129287A JPH08173170A (ja) 1994-05-25 1995-04-28 キャンディダ・ユティリス酵母の形質転換系、およびそれによる異種遺伝子の発現

Publications (1)

Publication Number Publication Date
ATE347598T1 true ATE347598T1 (de) 2006-12-15

Family

ID=27315910

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95919636T ATE347598T1 (de) 1994-05-25 1995-05-25 Transformierte linie der hefe candida utilis und die dadurch möglich expression eines heterogens

Country Status (11)

Country Link
US (1) US5849524A (de)
EP (2) EP1792993A1 (de)
JP (4) JPH08173170A (de)
KR (2) KR100263962B1 (de)
AT (1) ATE347598T1 (de)
AU (1) AU699864B2 (de)
CA (1) CA2168037C (de)
DE (1) DE69535326T2 (de)
FI (1) FI121013B (de)
NO (1) NO960247L (de)
WO (1) WO1995032289A1 (de)

Families Citing this family (33)

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Publication number Priority date Publication date Assignee Title
US6642021B2 (en) 1996-03-29 2003-11-04 University Of Maryland Methods of producing carotenoids by the expression of plant ε-cyclase genes
JP4158863B2 (ja) 1996-08-23 2008-10-01 キリンホールディングス株式会社 酵母ベクターおよびそれを用いたタンパク質の製造法
CU22722A1 (es) * 1996-10-03 2002-02-28 Ct Ingenieria Genetica Biotech Sistema de transformación para la expresión de genes heterólogos en la levadura candida utilis
DE19736343B4 (de) 1997-08-21 2006-02-09 Forschungszentrum Jülich GmbH Verfahren zur Erhöhung der Genexpression von Saccharose Synthase
WO1999057279A1 (en) * 1998-05-07 1999-11-11 Doosan Corporation Plasmid for gene expression in pichia ciferrii and transformation method using the same
JP2000342263A (ja) * 1999-06-02 2000-12-12 Japan Energy Corp ハイグロマイシン耐性遺伝子及び形質転換されたＣａｎｄｉｄａ属酵母
DE19963690A1 (de) * 1999-11-23 2001-06-13 Rhein Biotech Proz & Prod Gmbh Vektoren und Verfahren zur Herstellung rekombinanter Proteine in Pilzen
CN1301747A (zh) * 1999-12-27 2001-07-04 上海博德基因开发有限公司 一种新的多肽——核糖体s19e蛋白10和编码这种多肽的多核苷酸
US7141410B2 (en) * 2000-11-22 2006-11-28 Natureworks Llc Methods and materials for the production of organic products in cells of Candida species
JP2002325573A (ja) * 2001-04-27 2002-11-12 Japan Science & Technology Corp ベクター
US6645739B2 (en) * 2001-07-26 2003-11-11 Phoenix Pharmacologies, Inc. Yeast expression systems, methods of producing polypeptides in yeast, and compositions relating to same
JP4649109B2 (ja) * 2001-11-23 2011-03-09 カーギル ダウ エルエルシー カンジダ菌種の細胞における有機生成物の産生のための方法及び材料
BRPI0311517A2 (pt) 2002-05-30 2016-06-28 Cargill Dow Llc processo de fermentação empregando taxas de absorção de oxigênio específicas como um controle de processo
JP4587750B2 (ja) * 2004-09-13 2010-11-24 株式会社興人 転写活性化タンパク質をコードするキャンディダユティリス由来の遺伝子
JP4671394B2 (ja) * 2004-09-13 2011-04-13 株式会社興人 キャンディダ・ユティリス由来のプロモーターｄｎａ
JP4563228B2 (ja) * 2004-09-13 2010-10-13 株式会社興人 キャンディダ・ユティリス由来のａｒｓ遺伝子
AU2006227165B2 (en) 2005-03-18 2011-11-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
WO2008042338A2 (en) 2006-09-28 2008-04-10 Microbia, Inc. Production of carotenoids in oleaginous yeast and fungi
JP5030067B2 (ja) 2006-09-29 2012-09-19 国立大学法人 奈良先端科学技術大学院大学 新規アルカンポリオール脱水素酵素
US20090277974A1 (en) * 2008-05-06 2009-11-12 Samino Citrawireja Lawn And Garden Sprinkler Housing
WO2010024445A1 (ja) 2008-09-01 2010-03-04 ダイセル化学工業株式会社 光学活性なアミン誘導体を製造するための方法
US20110287494A1 (en) 2008-09-01 2011-11-24 Daicel Chemical Industries Ltd Process for production of optically active amine derivative
WO2010095750A1 (ja) * 2009-02-23 2010-08-26 キリンホールディングス株式会社 キシロースを炭素源として使用しうる、キャンディダ・ユティリスによる物質の製造法
US8158391B2 (en) 2009-05-06 2012-04-17 Dna Twopointo, Inc. Production of an α-carboxyl-ω-hydroxy fatty acid using a genetically modified Candida strain
US8597923B2 (en) * 2009-05-06 2013-12-03 SyntheZyme, LLC Oxidation of compounds using genetically modified Candida
WO2011052718A1 (ja) 2009-10-30 2011-05-05 ダイセル化学工業株式会社 １，３－ブタンジオール生産機能を付与された遺伝子組換え微生物及びその利用
CN103348014B (zh) 2010-10-05 2020-11-03 味之素株式会社 含有γ-Glu-Abu的酵母和酵母提取物以及它们的制备方法
WO2015005378A1 (ja) 2013-07-12 2015-01-15 味の素株式会社 Ａｂｕ、γ－Ｇｌｕ－Ａｂｕ、及び／又はγ－Ｇｌｕ－Ａｂｕ－Ｇｌｙを高含有する酵母
CA2996028A1 (en) 2015-08-24 2017-03-02 Ajinomoto Co., Inc. Method for producing phytosphingosine or sphinganine
EP3341488A1 (de) 2015-08-24 2018-07-04 Ajinomoto Co., Inc. Verfahren zur herstellung von sphingoid-base oder sphingolipid
CN112575013B (zh) * 2020-12-24 2022-05-17 广东省微生物研究所（广东省微生物分析检测中心） 基因gnatb作为筛选标记基因在抗性筛选中的应用
EP4281575A1 (de) 2021-01-20 2023-11-29 Ajinomoto Co., Inc. Verfahren zur herstellung von phytosphingosin oder phytoceramid
EP4281574A1 (de) 2021-01-20 2023-11-29 Ajinomoto Co., Inc. Verfahren zur herstellung von phytosphingosin oder phytoceramid

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1341116C (en) * 1983-02-22 2000-10-17 Rae Lyn Burke Yeast expression systems with vectors having gapdh or pyk promoters and synthesis or foreign protein
JPS59162884A (ja) * 1983-03-09 1984-09-13 Kohjin Co Ltd 新規な雑種プラスミドおよびそれを含有する微生物
GB8314961D0 (en) * 1983-05-31 1983-07-06 Kingsman A J Dna sequence
JPS60210815A (ja) * 1984-04-04 1985-10-23 Hitachi Ltd 変圧器鉄心
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
JPS6442673A (en) 1987-08-11 1989-02-14 Seiko Epson Corp Printer
JP3036002B2 (ja) 1990-07-06 2000-04-24 東洋紡績株式会社 キャンデイダ・ユテイリス由来のａｄｅ１遺伝子を含有するｄｎａ断片
FR2679253B1 (fr) * 1991-07-15 1994-09-02 Pasteur Institut Proteines de resistance a la cycloheximide. utilisation comme marqueur de selection par exemple pour controler le transfert d'acides nucleiques.
JP2984143B2 (ja) * 1992-05-15 1999-11-29 キッコーマン株式会社 新規なウリカーゼ遺伝子、新規な組み換え体ｄｎａ及びウリカーゼの製造法
JPH0614865A (ja) 1992-07-02 1994-01-25 Asahi Optical Co Ltd 内視鏡の先端部
DE4226971C2 (de) * 1992-08-14 1997-01-16 Widmar Prof Dr Tanner Modifizierte Pilzzellen und Verfahren zur Herstellung rekombinanter Produkte

Also Published As

Publication number Publication date
CA2168037A1 (en) 1995-11-30
JP4017966B2 (ja) 2007-12-05
JPH08173170A (ja) 1996-07-09
KR100263962B1 (ko) 2000-08-16
AU2537795A (en) 1995-12-18
JP3385027B2 (ja) 2003-03-10
EP1792993A1 (de) 2007-06-06
AU699864B2 (en) 1998-12-17
WO1995032289A1 (en) 1995-11-30
DE69535326T2 (de) 2007-06-21
NO960247L (no) 1996-03-22
KR100320905B1 (ko) 2002-01-23
FI960331A0 (fi) 1996-01-24
NO960247D0 (no) 1996-01-22
JP2003174879A (ja) 2003-06-24
FI960331L (fi) 1996-03-20
JP4623925B2 (ja) 2011-02-02
US5849524A (en) 1998-12-15
EP0717107B1 (de) 2006-12-06
JP2003144185A (ja) 2003-05-20
DE69535326D1 (de) 2007-01-18
FI121013B (fi) 2010-06-15
CA2168037C (en) 2003-07-01
EP0717107A1 (de) 1996-06-19
EP0717107A4 (de) 2002-05-22

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