ATE344289T1 - Polyethylenglykol-aldehydderivate - Google Patents

Polyethylenglykol-aldehydderivate

Info

Publication number: ATE344289T1
Authority: AT; Austria
Prior art keywords: polyethylene glycol; aldehyde derivatives; glycol aldehyde; derivatives; polyethylene
Prior art date: 2002-07-24

Application number

AT03766194T

Other languages

English (en)

Inventor

Chee-Youb Won

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-07-24

Filing date

2003-07-16

Publication date

2006-11-15

2003-07-16 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2006-11-15 Application granted granted Critical

2006-11-15 Publication of ATE344289T1 publication Critical patent/ATE344289T1/de

Classifications

- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/321—Polymers modified by chemical after-treatment with inorganic compounds
- C08G65/324—Polymers modified by chemical after-treatment with inorganic compounds containing oxygen
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
- C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
- C08G65/2615—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen the other compounds containing carboxylic acid, ester or anhydride groups
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
- C08G65/2618—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen
- C08G65/2621—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups
- C08G65/2624—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing nitrogen containing amine groups containing aliphatic amine groups
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
- C08G65/331—Polymers modified by chemical after-treatment with organic compounds containing oxygen

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicinal Chemistry (AREA)
Polymers & Plastics (AREA)
General Chemical & Material Sciences (AREA)
Inorganic Chemistry (AREA)
Polyethers (AREA)
Medicinal Preparation (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Hydrogenated Pyridines (AREA)
Saccharide Compounds (AREA)

AT03766194T 2002-07-24 2003-07-16 Polyethylenglykol-aldehydderivate ATE344289T1 (de)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US39819602P	2002-07-24	2002-07-24

Publications (1)

Publication Number	Publication Date
ATE344289T1 true ATE344289T1 (de)	2006-11-15

Family

ID=31495721

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03766194T ATE344289T1 (de)	2002-07-24	2003-07-16	Polyethylenglykol-aldehydderivate

Country Status (28)

Country	Link
US (2)	US7273909B2 (de)
EP (1)	EP1539857B1 (de)
JP (1)	JP4071238B2 (de)
KR (1)	KR100615753B1 (de)
CN (1)	CN1671769B (de)
AR (1)	AR040607A1 (de)
AT (1)	ATE344289T1 (de)
AU (1)	AU2003250971B2 (de)
BR (1)	BR0312863B1 (de)
CA (1)	CA2493221C (de)
DE (1)	DE60309482T2 (de)
DK (1)	DK1539857T3 (de)
ES (1)	ES2274277T3 (de)
GT (1)	GT200300154A (de)
HR (1)	HRP20050026A2 (de)
IL (1)	IL165920A0 (de)
JO (1)	JO2400B1 (de)
MX (1)	MXPA05000799A (de)
NO (1)	NO336974B1 (de)
PA (1)	PA8577601A1 (de)
PE (1)	PE20040703A1 (de)
PL (1)	PL214871B1 (de)
PT (1)	PT1539857E (de)
RU (1)	RU2288212C2 (de)
TW (1)	TWI276647B (de)
UY (1)	UY27902A1 (de)
WO (1)	WO2004013205A1 (de)
ZA (1)	ZA200410296B (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MXPA05002632A (es)	2002-09-09	2005-09-20	Nektar Therapeutics Al Corp	Metodo para preparar derivados de polimeros solubles en agua que portan un acido carboxilico terminal.
CA2498167C (en)	2002-09-09	2012-03-20	Nektar Therapeutics Al, Corporation	Water-soluble polymer alkanals
US20050214250A1 (en)	2003-11-06	2005-09-29	Harris J M	Method of preparing carboxylic acid functionalized polymers
US7989554B2 (en) *	2006-01-10	2011-08-02	Enzon Pharmaceuticals, Inc.	Reacting polyalkylene oxide with base, tertiary alkyl haloacetate, then acid to prepare polyalkylene oxide carboxylic acid
US20090252703A1 (en) *	2006-10-19	2009-10-08	Gegg Jr Colin V	Use of alcohol co-solvents to improve pegylation reaction yields
WO2008048079A1 (en) *	2006-10-20	2008-04-24	Postech Academy-Industry Foundation	Long acting formulation of biopharmaceutical
US8247493B2 (en) *	2007-10-22	2012-08-21	Postech Academy-Industry Foundation	Long acting formulation of biopharmaceutical
KR100967833B1 (ko) *	2008-05-20	2010-07-05	아이디비켐(주)	고순도의 폴리에틸렌글리콜 알데하이드 유도체의 제조방법
JP5766118B2 (ja) *	2008-09-11	2015-08-19	ウェルズファーゴバンクナショナルアソシエイション	ポリマー性アルファ−ヒドロキシアルデヒドおよびケトン反応剤ならびに抱合方法
EP2592103A1 (de)	2011-11-08	2013-05-15	Adriacell S.p.A.	Polymeraldehydderivate
BR112015032200A2 (pt) *	2013-06-24	2017-11-21	Hanwha Chemical Corp	conjugado anticorpo-droga com estabilidade melhorada, método de preparação, composição farmacêutica e uso do mesmo
KR102247701B1 (ko) *	2016-02-26	2021-05-03	한미정밀화학주식회사	폴리에틸렌글리콜 디알데히드 유도체의 제조방법
AR107823A1 (es) *	2016-03-07	2018-06-06	Hanmi Pharm Ind Co Ltd	Derivados de polietilenglicol y uso de los mismos
JP7377195B2 (ja)	2017-09-29	2023-11-09	ハンミファーマシューティカルカンパニーリミテッド	リンカーとして非ペプチド性重合体結合脂肪酸誘導体化合物を含むタンパク質結合体及びその製造方法
EP4448556A1 (de)	2021-12-16	2024-10-23	RDP Pharma AG	Zellpenetrierende polypeptide (cpps) und deren verwendung in der humantherapie
EP4480497A1 (de)	2023-06-21	2024-12-25	RDP Pharma AG	Biokonjugate für die onkologie

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5252714A (en) *	1990-11-28	1993-10-12	The University Of Alabama In Huntsville	Preparation and use of polyethylene glycol propionaldehyde
CH690143A5 (de) *	1995-01-27	2000-05-15	Rieter Automotive Int Ag	Lambda/4-Schallabsorber.
US5672662A (en) *	1995-07-07	1997-09-30	Shearwater Polymers, Inc.	Poly(ethylene glycol) and related polymers monosubstituted with propionic or butanoic acids and functional derivatives thereof for biotechnical applications
US5990237A (en) *	1997-05-21	1999-11-23	Shearwater Polymers, Inc.	Poly(ethylene glycol) aldehyde hydrates and related polymers and applications in modifying amines
WO2000024697A1 (en) *	1998-10-26	2000-05-04	University Of Utah Research Foundation	Method for preparation of polyethylene glycol aldehyde derivatives
PE20010288A1 (es) *	1999-07-02	2001-03-07	Hoffmann La Roche	Derivados de eritropoyetina
KR100488351B1 (ko) *	2001-12-11	2005-05-11	선바이오(주)	신규한 폴리에틸렌글리콜-프로피온알데히드 유도체
WO2003049699A2 (en)	2001-12-11	2003-06-19	Sun Bio, Inc.	Novel monofunctional polyethylene glycol aldehydes

2003
- 2003-07-16 AT AT03766194T patent/ATE344289T1/de active
- 2003-07-16 CN CN038176491A patent/CN1671769B/zh not_active Expired - Fee Related
- 2003-07-16 ES ES03766194T patent/ES2274277T3/es not_active Expired - Lifetime
- 2003-07-16 RU RU2005105568/04A patent/RU2288212C2/ru not_active IP Right Cessation
- 2003-07-16 MX MXPA05000799A patent/MXPA05000799A/es active IP Right Grant
- 2003-07-16 WO PCT/EP2003/007734 patent/WO2004013205A1/en active IP Right Grant
- 2003-07-16 CA CA002493221A patent/CA2493221C/en not_active Expired - Fee Related
- 2003-07-16 AU AU2003250971A patent/AU2003250971B2/en not_active Ceased
- 2003-07-16 BR BRPI0312863-6A patent/BR0312863B1/pt not_active IP Right Cessation
- 2003-07-16 PL PL375266A patent/PL214871B1/pl unknown
- 2003-07-16 DE DE60309482T patent/DE60309482T2/de not_active Expired - Lifetime
- 2003-07-16 DK DK03766194T patent/DK1539857T3/da active
- 2003-07-16 EP EP03766194A patent/EP1539857B1/de not_active Expired - Lifetime
- 2003-07-16 KR KR1020057001223A patent/KR100615753B1/ko not_active IP Right Cessation
- 2003-07-16 PT PT03766194T patent/PT1539857E/pt unknown
- 2003-07-16 JP JP2004525223A patent/JP4071238B2/ja not_active Expired - Fee Related
- 2003-07-20 JO JO200383A patent/JO2400B1/en active
- 2003-07-21 AR AR20030102609A patent/AR040607A1/es not_active Application Discontinuation
- 2003-07-21 US US10/623,978 patent/US7273909B2/en not_active Expired - Fee Related
- 2003-07-21 PA PA20038577601A patent/PA8577601A1/es unknown
- 2003-07-21 TW TW092119827A patent/TWI276647B/zh not_active IP Right Cessation
- 2003-07-21 PE PE2003000727A patent/PE20040703A1/es not_active Application Discontinuation
- 2003-07-22 UY UY27902A patent/UY27902A1/es not_active Application Discontinuation
- 2003-07-23 GT GT200300154A patent/GT200300154A/es unknown
2004
- 2004-12-21 ZA ZA200410296A patent/ZA200410296B/en unknown
- 2004-12-22 IL IL16592004A patent/IL165920A0/xx not_active IP Right Cessation
2005
- 2005-01-03 NO NO20050019A patent/NO336974B1/no not_active IP Right Cessation
- 2005-01-11 HR HR20050026A patent/HRP20050026A2/hr not_active Application Discontinuation
2007
- 2007-03-14 US US11/724,009 patent/US20070167606A1/en not_active Abandoned

Also Published As

Publication number	Publication date
UY27902A1 (es)	2003-12-31
JP2005533913A (ja)	2005-11-10
PE20040703A1 (es)	2004-10-14
CN1671769B (zh)	2010-05-12
CN1671769A (zh)	2005-09-21
CA2493221C (en)	2008-11-18
AR040607A1 (es)	2005-04-13
EP1539857B1 (de)	2006-11-02
JO2400B1 (en)	2007-06-17
KR100615753B1 (ko)	2006-08-25
AU2003250971A1 (en)	2004-02-23
RU2288212C2 (ru)	2006-11-27
US7273909B2 (en)	2007-09-25
ZA200410296B (en)	2006-07-26
PT1539857E (pt)	2007-01-31
RU2005105568A (ru)	2005-10-20
AU2003250971B2 (en)	2008-04-03
IL165920A0 (en)	2006-01-15
WO2004013205A1 (en)	2004-02-12
PL375266A1 (en)	2005-11-28
TW200416241A (en)	2004-09-01
TWI276647B (en)	2007-03-21
DE60309482D1 (de)	2006-12-14
US20070167606A1 (en)	2007-07-19
KR20050025974A (ko)	2005-03-14
BR0312863A (pt)	2005-06-14
NO20050019L (no)	2005-02-23
JP4071238B2 (ja)	2008-04-02
PL214871B1 (pl)	2013-09-30
MXPA05000799A (es)	2005-04-19
HRP20050026A2 (en)	2006-02-28
GT200300154A (es)	2004-03-15
NO336974B1 (no)	2015-12-07
BR0312863B1 (pt)	2013-02-05
DE60309482T2 (de)	2007-06-28
US20040019157A1 (en)	2004-01-29
ES2274277T3 (es)	2007-05-16
PA8577601A1 (es)	2004-02-07
CA2493221A1 (en)	2004-02-12
EP1539857A1 (de)	2005-06-15
DK1539857T3 (da)	2007-03-12

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DK1682129T3 (da)	2007-06-11	N-thiazol-2-ylbenzamidderivater
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ATE449064T1 (de)	2009-12-15	Amidoacetonitrilderivate
IS8045A (is)	2005-09-26	Púrín-6-ón-afleiður
DE50306277D1 (de)	2007-02-22	4-alkyl-/4-alkenyl-/4-alkinylmethyl/-1-arylcyclohexylamin-derivate
NO20024789D0 (no)	2002-10-03	Stötfanger
DE502004002157D1 (de)	2007-01-11	Bewegungshemmnis

Legal Events

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2007-07-15	UEP	Publication of translation of european patent specification	Ref document number: 1539857 Country of ref document: EP

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