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ATE329691T1 - Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte - Google Patents

Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte

Info

Publication number
ATE329691T1
ATE329691T1 AT00991793T AT00991793T ATE329691T1 AT E329691 T1 ATE329691 T1 AT E329691T1 AT 00991793 T AT00991793 T AT 00991793T AT 00991793 T AT00991793 T AT 00991793T AT E329691 T1 ATE329691 T1 AT E329691T1
Authority
AT
Austria
Prior art keywords
nucleic acid
treating
integrated microfluidic
thermocycling reaction
microfluidic plate
Prior art date
Application number
AT00991793T
Other languages
English (en)
Inventor
Nigel Eric Tooke
Per Andersson
Original Assignee
Gyros Patent Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/010347 external-priority patent/WO2000040750A1/en
Priority claimed from GBGB0011425.6A external-priority patent/GB0011425D0/en
Application filed by Gyros Patent Ab filed Critical Gyros Patent Ab
Application granted granted Critical
Publication of ATE329691T1 publication Critical patent/ATE329691T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0631—Purification arrangements, e.g. solid phase extraction [SPE]
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B01L2300/0806—Standardised forms, e.g. compact disc [CD] format
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B01L2300/087—Multiple sequential chambers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0415—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic
    • B01L2400/0421—Moving fluids with specific forces or mechanical means specific forces electrical forces, e.g. electrokinetic electrophoretic flow
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/088—Passive control of flow resistance by specific surface properties
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Saccharide Compounds (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Cereal-Derived Products (AREA)
AT00991793T 1999-12-23 2000-12-20 Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte ATE329691T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1999/010347 WO2000040750A1 (en) 1998-12-30 1999-12-23 Method for sequencing dna using a microfluidic device
GBGB0011425.6A GB0011425D0 (en) 1999-12-23 2000-05-12 Integrated microfluidic disc

Publications (1)

Publication Number Publication Date
ATE329691T1 true ATE329691T1 (de) 2006-07-15

Family

ID=26070393

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00991793T ATE329691T1 (de) 1999-12-23 2000-12-20 Verfahren zur behandlung einer matrixnukleinsäure unter verwendung einer integrierten mikrofluidischen platte

Country Status (5)

Country Link
JP (1) JP4791670B2 (de)
AT (1) ATE329691T1 (de)
AU (1) AU3537001A (de)
DE (1) DE60028819T2 (de)
WO (1) WO2001047638A2 (de)

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US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
WO2002046721A2 (en) 2000-12-08 2002-06-13 Burstein Technologies, Inc. Optical discs for measuring analytes
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
WO2002075312A1 (en) 2001-03-19 2002-09-26 Gyros Ab Characterization of reaction variables
US6726820B1 (en) 2001-09-19 2004-04-27 Applera Corporation Method of separating biomolecule-containing samples with a microdevice with integrated memory
US20080288178A1 (en) 2001-08-24 2008-11-20 Applera Corporation Sequencing system with memory
WO2003018198A1 (en) 2001-08-28 2003-03-06 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
ATE477054T1 (de) 2001-09-17 2010-08-15 Gyros Patent Ab Einen kontrollierten strom in einer mikrofluidvorrichtung ermöglichende funktionseinheit
WO2003044481A2 (en) 2001-11-20 2003-05-30 Burstein Technologies, Inc. Optical bio-discs and microfluidic devices for analysis of cells
US6532997B1 (en) 2001-12-28 2003-03-18 3M Innovative Properties Company Sample processing device with integral electrophoresis channels
US7662340B2 (en) * 2001-12-28 2010-02-16 Hitachi High-Technologies Corporation Extractor chemical analyzer and chemical analyzing method
JP4895504B2 (ja) * 2002-04-30 2012-03-14 ユィロス・パテント・アクチボラグ 集中マイクロ流体デバイス（ｅａ）
US7005265B1 (en) 2002-06-20 2006-02-28 Wenhong Fan Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
JP2004354364A (ja) 2002-12-02 2004-12-16 Nec Corp 微粒子操作ユニット、それを搭載したチップと検出装置、ならびにタンパク質の分離、捕獲、および検出方法
US7390464B2 (en) 2003-06-19 2008-06-24 Burstein Technologies, Inc. Fluidic circuits for sample preparation including bio-discs and methods relating thereto
US7238269B2 (en) * 2003-07-01 2007-07-03 3M Innovative Properties Company Sample processing device with unvented channel
US7776272B2 (en) 2003-10-03 2010-08-17 Gyros Patent Ab Liquid router
US7837947B2 (en) 2003-12-12 2010-11-23 3M Innovative Properties Company Sample mixing on a microfluidic device
SE0400181D0 (sv) 2004-01-29 2004-01-29 Gyros Ab Segmented porous and preloaded microscale devices
US7187286B2 (en) 2004-03-19 2007-03-06 Applera Corporation Methods and systems for using RFID in biological field
TWI295730B (en) * 2004-11-25 2008-04-11 Ind Tech Res Inst Microfluidic chip for sample assay and method thereof
US7947235B2 (en) 2005-04-14 2011-05-24 Gyros Ab Microfluidic device with finger valves
US10816563B2 (en) 2005-05-25 2020-10-27 Boehringer Ingelheim Vetmedica Gmbh System for operating a system for the integrated and automated analysis of DNA or protein
DK1883474T3 (da) 2005-05-25 2021-06-21 Boehringer Ingelheim Vetmedica Gmbh System til integreret og automatiseret dna- eller proteinanalyse og fremgangsmåde til at drive et sådan system
US20090075801A1 (en) * 2007-09-19 2009-03-19 Dalibor Hodko Counter-centrifugal force device
US20130149710A1 (en) 2010-09-07 2013-06-13 The Arizona Board Of Regents On Behalf Of The University Of Arizona Microdroplet-manipulation systems and methods for automated execution of molecular biological protocols
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
EP3523035B1 (de) 2016-10-07 2020-07-29 Boehringer Ingelheim Vetmedica GmbH Analysevorrichtung und verfahren zum testen einer probe
JP2019537706A (ja) 2016-10-07 2019-12-26 ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーＢｏｅｈｒｉｎｇｅｒ Ｉｎｇｅｌｈｅｉｍ Ｖｅｔｍｅｄｉｃａ ＧｍｂＨ サンプルを検査するための方法及び分析システム
EP3746222A1 (de) 2018-01-30 2020-12-09 Life Technologies Corporation Instrumente, vorrichtungen und verbrauchsmaterialien zur verwendung in einem workflow eines intelligenten molekulardiagnostischen analysesystems

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JP2002503331A (ja) * 1995-12-05 2002-01-29 ガメラ バイオサイエンス コーポレイション 機内に搭載された情報科学を備えた超微量液体素子工学システムにおいて液体移動を推進するために求心性加速を使用するための装置及び方法
GB2337113B (en) * 1997-02-28 2001-03-21 Burstein Lab Inc Laboratory in a disk
US6013513A (en) * 1997-10-30 2000-01-11 Motorola, Inc. Molecular detection apparatus
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems
JP3623479B2 (ja) * 1999-06-22 2005-02-23 テカン トレーディング アーゲー 小型化されたインビトロ増幅アッセイを行うための装置および方法

Also Published As

Publication number Publication date
DE60028819D1 (de) 2006-07-27
DE60028819T2 (de) 2007-01-11
JP2003520582A (ja) 2003-07-08
WO2001047638A3 (en) 2002-05-30
WO2001047638A2 (en) 2001-07-05
AU3537001A (en) 2001-07-09
JP4791670B2 (ja) 2011-10-12

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