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ATE319827T1 - Polypeptid, das die differenzierung unterdrueckt - Google Patents

Polypeptid, das die differenzierung unterdrueckt

Info

Publication number
ATE319827T1
ATE319827T1 AT96938478T AT96938478T ATE319827T1 AT E319827 T1 ATE319827 T1 AT E319827T1 AT 96938478 T AT96938478 T AT 96938478T AT 96938478 T AT96938478 T AT 96938478T AT E319827 T1 ATE319827 T1 AT E319827T1
Authority
AT
Austria
Prior art keywords
polypeptide
differentiation
suppresses differentiation
supression
efficacious
Prior art date
Application number
AT96938478T
Other languages
English (en)
Inventor
Seiji Sakano
Akira Itoh
Original Assignee
Asahi Chemical Ind
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Chemical Ind filed Critical Asahi Chemical Ind
Application granted granted Critical
Publication of ATE319827T1 publication Critical patent/ATE319827T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT96938478T 1995-11-17 1996-11-15 Polypeptid, das die differenzierung unterdrueckt ATE319827T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP29961195 1995-11-17
JP31181195 1995-11-30

Publications (1)

Publication Number Publication Date
ATE319827T1 true ATE319827T1 (de) 2006-03-15

Family

ID=26561997

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96938478T ATE319827T1 (de) 1995-11-17 1996-11-15 Polypeptid, das die differenzierung unterdrueckt

Country Status (7)

Country Link
US (5) US6337387B1 (de)
EP (1) EP0861894B1 (de)
JP (1) JP4283891B2 (de)
AT (1) ATE319827T1 (de)
AU (1) AU716889B2 (de)
DE (1) DE69635899T2 (de)
WO (1) WO1997019172A1 (de)

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US5786158A (en) * 1992-04-30 1998-07-28 Yale University Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
US20050112121A1 (en) * 1992-04-30 2005-05-26 Yale University Therapeutic and diagnostic methods and compositions based on notch proteins and nucleic acids
WO2000053753A2 (en) * 1999-03-08 2000-09-14 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
WO2000032221A2 (en) * 1998-12-01 2000-06-08 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
DE69638023D1 (de) 1995-06-28 2009-10-22 Univ Yale Nukleotid- und proteinsequenzen von delta-genen von vertebraten und darauf basierende methoden
US5780300A (en) * 1995-09-29 1998-07-14 Yale University Manipulation of non-terminally differentiated cells using the notch pathway
AU716889B2 (en) * 1995-11-17 2000-03-09 Asahi Kasei Kogyo Kabushiki Kaisha Differentiation-suppressive polypeptide
US6716974B1 (en) * 1996-05-31 2004-04-06 Maine Medical Center Research Institute Therapeutic and diagnostic methods and compositions based on jagged/notch proteins and nucleic acids
DE69736109T2 (de) 1996-07-16 2007-01-04 Asahi Kasei Kabushiki Kaisha Differenzierungsinhibitor
IL129531A0 (en) * 1996-11-07 2000-02-29 Lorantis Ltd Ligands to notch proteins
US6887475B1 (en) 1996-11-07 2005-05-03 Lorantis Limited Notch
US6121045A (en) * 1997-04-04 2000-09-19 Millennium Biotherapeutics, Inc. Human Delta3 nucleic acid molecules
DE69836131T3 (de) * 1997-04-04 2017-06-14 Millennium Pharmaceuticals, Inc. Neue menschliche delta3-zusammensetzung und deren therapeutische und diagnostische verwendungen
US20060122373A1 (en) 1997-04-04 2006-06-08 Millennium Pharmaceuticals, Inc. Delta3, FTHMA-070, Tango85, Tango77, SPOIL,NEOKINE, Tango129 and integrin alpha subunit protein and nucleic acid molecules and uses thereof
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US6136952A (en) * 1997-06-25 2000-10-24 University Of Washington Human jagged polypeptide, encoding nucleic acids and methods of use
US6692919B1 (en) 1997-07-23 2004-02-17 Yale University Activated forms of notch and methods based thereon
US6436650B1 (en) 1997-07-23 2002-08-20 Yale University Activated forms of notch and methods based thereon
EP1518930B1 (de) * 1998-10-13 2007-05-30 Genentech, Inc. Verfahren und Zusammenstzung zur Hemmung des Wachtums von neoplastischen Zellen
JP4493854B2 (ja) * 1998-12-23 2010-06-30 リジェネロン・ファーマシューティカルズ・インコーポレイテッド リガンドの生物学的活性を増強する方法
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US5869282A (en) * 1991-12-11 1999-02-09 Imperial Cancer Research Technology, Ltd. Nucleotide and protein sequences of the serrate gene and methods based thereon
WO1993012141A1 (en) * 1991-12-11 1993-06-24 Yale University Nucleotide and protein sequences of the serrate gene and methods based thereon
US5864020A (en) 1994-07-20 1999-01-26 Genentech, Inc. HTK ligand
WO1996011212A1 (fr) 1994-10-07 1996-04-18 Asahi Kasei Kogyo Kabushiki Kaisha Nouveau ligand de tyrosine kinase de type recepteur
DE69638023D1 (de) * 1995-06-28 2009-10-22 Univ Yale Nukleotid- und proteinsequenzen von delta-genen von vertebraten und darauf basierende methoden
AU716889B2 (en) * 1995-11-17 2000-03-09 Asahi Kasei Kogyo Kabushiki Kaisha Differentiation-suppressive polypeptide

Also Published As

Publication number Publication date
US7198918B2 (en) 2007-04-03
AU716889B2 (en) 2000-03-09
US7253265B2 (en) 2007-08-07
US20050164348A1 (en) 2005-07-28
EP0861894B1 (de) 2006-03-08
US6337387B1 (en) 2002-01-08
DE69635899D1 (de) 2006-05-04
US20050130271A1 (en) 2005-06-16
EP0861894A1 (de) 1998-09-02
US20050130268A1 (en) 2005-06-16
DE69635899T2 (de) 2006-11-23
EP0861894A4 (de) 2002-08-07
JP4283891B2 (ja) 2009-06-24
US20020128197A1 (en) 2002-09-12
WO1997019172A1 (fr) 1997-05-29
US7179622B2 (en) 2007-02-20
US7141379B2 (en) 2006-11-28
AU7587696A (en) 1997-06-11

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