ATE312352T1 - Hämatologische bestimmung und reagenz - Google Patents
Hämatologische bestimmung und reagenzInfo
- Publication number
- ATE312352T1 ATE312352T1 AT00991194T AT00991194T ATE312352T1 AT E312352 T1 ATE312352 T1 AT E312352T1 AT 00991194 T AT00991194 T AT 00991194T AT 00991194 T AT00991194 T AT 00991194T AT E312352 T1 ATE312352 T1 AT E312352T1
- Authority
- AT
- Austria
- Prior art keywords
- factor
- reagent
- coagulation
- activator
- body fluid
- Prior art date
Links
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 230000002489 hematologic effect Effects 0.000 title abstract 2
- 230000015271 coagulation Effects 0.000 abstract 3
- 238000005345 coagulation Methods 0.000 abstract 3
- GONFBOIJNUKKST-UHFFFAOYSA-N 5-ethylsulfanyl-2h-tetrazole Chemical compound CCSC=1N=NNN=1 GONFBOIJNUKKST-UHFFFAOYSA-N 0.000 abstract 2
- 210000001124 body fluid Anatomy 0.000 abstract 2
- 239000010839 body fluid Substances 0.000 abstract 2
- UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 abstract 1
- 206010053567 Coagulopathies Diseases 0.000 abstract 1
- 241000271032 Daboia russelii Species 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108010014172 Factor V Proteins 0.000 abstract 1
- 101710144447 Factor V activator Proteins 0.000 abstract 1
- 108010074105 Factor Va Proteins 0.000 abstract 1
- 108010074860 Factor Xa Proteins 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 238000003556 assay Methods 0.000 abstract 1
- 230000023555 blood coagulation Effects 0.000 abstract 1
- 239000007853 buffer solution Substances 0.000 abstract 1
- 229910001628 calcium chloride Inorganic materials 0.000 abstract 1
- 239000001110 calcium chloride Substances 0.000 abstract 1
- 239000003593 chromogenic compound Substances 0.000 abstract 1
- 230000035602 clotting Effects 0.000 abstract 1
- 230000001939 inductive effect Effects 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 150000003904 phospholipids Chemical class 0.000 abstract 1
- 108090001115 snake venom factor V activator Proteins 0.000 abstract 1
- 239000002821 viper venom Substances 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
- G01N2333/4609—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
- G01N2333/4613—Snake venom
- G01N2333/4616—Snake venom from Russell's viper
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/745—Assays involving non-enzymic blood coagulation factors
- G01N2333/7456—Factor V
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
- G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
- G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
- G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
- G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
- G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
- G01N2333/96433—Serine endopeptidases (3.4.21)
- G01N2333/96441—Serine endopeptidases (3.4.21) with definite EC number
- G01N2333/96444—Factor X (3.4.21.6)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP1999/009952 WO2001044493A2 (en) | 1999-12-15 | 1999-12-15 | Hematological assay and reagent |
| PCT/EP2000/012753 WO2001044819A2 (en) | 1999-12-15 | 2000-12-14 | Hematological assay and reagent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE312352T1 true ATE312352T1 (de) | 2005-12-15 |
Family
ID=8167528
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT00991194T ATE312352T1 (de) | 1999-12-15 | 2000-12-14 | Hämatologische bestimmung und reagenz |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6994984B2 (de) |
| EP (1) | EP1240528B1 (de) |
| JP (1) | JP4762472B2 (de) |
| AT (1) | ATE312352T1 (de) |
| AU (2) | AU2431800A (de) |
| CA (1) | CA2392350C (de) |
| DE (1) | DE60024669T2 (de) |
| ES (1) | ES2254260T3 (de) |
| WO (2) | WO2001044493A2 (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6680177B2 (en) * | 2001-12-07 | 2004-01-20 | Cardiovascular Diagnostics, Inc. | Low molecular weight heparin assay, system and reagent therefor |
| US7358337B2 (en) * | 2002-08-16 | 2008-04-15 | International Technidyne Corporation | Assay for low molecular weight heparin |
| WO2005031303A2 (en) * | 2003-09-22 | 2005-04-07 | University Of North Carolina At Chapel Hill | Soluble phospholipids for use in clotting factor assays |
| CA2566411A1 (en) | 2004-05-11 | 2005-11-24 | Heptest Laboratories, Inc. | Compositions, kit and one-step method for monitoring compounds having anti-factor xa and/or anti factor iia activities |
| GB2433592A (en) * | 2005-12-23 | 2007-06-27 | Pentapharm Ag | Assay for thrombin inhibitors |
| EP1918718A1 (de) | 2006-10-31 | 2008-05-07 | Roche Diagnostics GmbH | Verfahren und Vorrichtungen zur elektrochemischen Bestimmung von Faktor Xa-Inhibitoren in Blutproben |
| EP2333555A1 (de) | 2009-12-09 | 2011-06-15 | Siemens Healthcare Diagnostics Products GmbH | Heterogener Gerinnungstest |
| JP2011133396A (ja) * | 2009-12-25 | 2011-07-07 | Sysmex Corp | 活性化部分トロンボプラスチン時間測定試薬、活性化部分トロンボプラスチン時間測定方法、及び血液凝固抑制物質の有無の判定方法 |
| EP2484775A1 (de) * | 2011-02-07 | 2012-08-08 | Siemens Healthcare Diagnostics Products GmbH | Heparin-insensitives Verfahren zur Bestimmung von direkten Gerinnungsfaktorinhibitoren |
| RU2517116C2 (ru) * | 2012-07-03 | 2014-05-27 | Государственное бюджетное учреждение Санкт-Петербургский научно-исследовательский институт скорой помощи им. И.И. Джанелидзе | Способ оценки состояния свертывающей системы крови у пациентов, находящихся в критическом состоянии |
| US10001495B2 (en) | 2012-07-25 | 2018-06-19 | Bioverativ Therapeutics Inc. | Blood factor monitoring assay and uses thereof |
| ES2680932T3 (es) * | 2013-05-14 | 2018-09-11 | Struszym, S.L. | Métodos de determinación de actividades de los factores de coagulación |
| US20160305966A1 (en) | 2013-12-09 | 2016-10-20 | Dsm Ip Assets B.V. | Identification of anticoagulants in a sample |
| EP3209323B1 (de) | 2014-10-23 | 2024-06-12 | Q-Sera Pty Ltd | Verbesserte gerinnungszusammensetzung |
| JP6873833B2 (ja) * | 2017-06-09 | 2021-05-19 | シスメックス株式会社 | 血液検体の判定方法、血液検体分析装置及びコンピュータプログラム |
| JP7110360B2 (ja) | 2017-10-09 | 2022-08-01 | テルモ ビーシーティー バイオテクノロジーズ，エルエルシー | 凍結乾燥方法 |
| CN108982865B (zh) * | 2018-08-16 | 2021-05-11 | 上海原科实业发展有限公司 | 一种血栓弹力图法肝素定量检测试剂盒及其制备方法 |
| CN109082458B (zh) * | 2018-08-16 | 2024-02-23 | 上海原科实业发展有限公司 | 一种血栓弹力图法定量检测口服凝血因子Xa抑制剂试剂盒及其制备方法 |
| CN109709344A (zh) * | 2018-12-29 | 2019-05-03 | 贵州金玖生物技术有限公司 | 一种活化凝血检测试剂、其制备方法及其应用 |
| CA3130700A1 (en) | 2019-03-14 | 2020-09-17 | Terumo Bct Biotechnologies, Llc | Lyophilization container fill fixture, system and method of use |
| CN110244066A (zh) * | 2019-07-01 | 2019-09-17 | 北京乐普医疗科技有限责任公司 | 一种干式电化学法凝血酶原时间检测卡及制备方法 |
| CN110887970B (zh) * | 2019-11-29 | 2023-10-31 | 北京赛科希德科技股份有限公司 | 抽提缓冲液、兔脑抽提液、pt检测试剂及pt检测试剂盒 |
| US20240044921A1 (en) * | 2020-12-28 | 2024-02-08 | Fujimori Kogyo Co., Ltd. | Method for evaluating blood coagulation performance, and method for inspecting risk of thrombosis |
| JPWO2022145477A1 (de) * | 2020-12-28 | 2022-07-07 | ||
| WO2022212162A1 (en) * | 2021-03-31 | 2022-10-06 | Haemonetics Corporation | Hemostasis measurement device quality control formulations |
| CN114703252B (zh) * | 2022-06-02 | 2022-11-04 | 深圳市帝迈生物技术有限公司 | 一种用于检测血浆中水蛭素、比伐卢定、达比加群含量的试剂盒 |
| WO2024163247A1 (en) * | 2023-02-01 | 2024-08-08 | Haemonetics Corporation | Disposable cartridge for classification of anticoagulant and method of use |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3516579A1 (de) | 1984-11-19 | 1986-05-22 | Boehringer Mannheim Gmbh, 6800 Mannheim | Gerinnungstest auf teststreifen |
| US5164598A (en) | 1985-08-05 | 1992-11-17 | Biotrack | Capillary flow device |
| US4756884A (en) | 1985-08-05 | 1988-07-12 | Biotrack, Inc. | Capillary flow device |
| US4946775A (en) * | 1985-09-05 | 1990-08-07 | Yin E Thye | Composition, kit and method for assaying heparin and a method for making the composition |
| DE3616496A1 (de) | 1986-05-16 | 1987-11-19 | Boehringer Mannheim Gmbh | Analyseelement zur bestimmung von gerinnungsparametern |
| US5110727A (en) | 1987-04-03 | 1992-05-05 | Cardiovascular Diagnostics, Inc. | Method for performing coagulation assays accurately, rapidly and simply, using dry chemical reagents and paramagnetic particles |
| US5266462A (en) * | 1992-06-03 | 1993-11-30 | Baxter Diagnostics Inc. | Measurement of platelet activities |
| WO1999002992A1 (en) * | 1997-07-11 | 1999-01-21 | The Mount Sinai School Of Medicine Of The City University Of New York | Assays for diagnosis of thrombophilic disease |
-
1999
- 1999-12-15 WO PCT/EP1999/009952 patent/WO2001044493A2/en active Application Filing
- 1999-12-15 AU AU24318/00A patent/AU2431800A/en not_active Abandoned
-
2000
- 2000-12-14 US US10/168,473 patent/US6994984B2/en not_active Expired - Lifetime
- 2000-12-14 DE DE60024669T patent/DE60024669T2/de not_active Expired - Lifetime
- 2000-12-14 AT AT00991194T patent/ATE312352T1/de not_active IP Right Cessation
- 2000-12-14 CA CA2392350A patent/CA2392350C/en not_active Expired - Lifetime
- 2000-12-14 EP EP00991194A patent/EP1240528B1/de not_active Expired - Lifetime
- 2000-12-14 JP JP2001545856A patent/JP4762472B2/ja not_active Expired - Lifetime
- 2000-12-14 ES ES00991194T patent/ES2254260T3/es not_active Expired - Lifetime
- 2000-12-14 AU AU31593/01A patent/AU776845B2/en not_active Expired
- 2000-12-14 WO PCT/EP2000/012753 patent/WO2001044819A2/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| EP1240528A2 (de) | 2002-09-18 |
| EP1240528B1 (de) | 2005-12-07 |
| WO2001044819A2 (en) | 2001-06-21 |
| AU776845B2 (en) | 2004-09-23 |
| US20030104508A1 (en) | 2003-06-05 |
| WO2001044819A3 (en) | 2001-12-06 |
| AU2431800A (en) | 2001-06-25 |
| DE60024669D1 (de) | 2006-01-12 |
| CA2392350C (en) | 2010-11-02 |
| WO2001044493A2 (en) | 2001-06-21 |
| US6994984B2 (en) | 2006-02-07 |
| DE60024669T2 (de) | 2006-09-28 |
| ES2254260T3 (es) | 2006-06-16 |
| AU3159301A (en) | 2001-06-25 |
| JP2003517610A (ja) | 2003-05-27 |
| JP4762472B2 (ja) | 2011-08-31 |
| CA2392350A1 (en) | 2001-06-21 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1240528 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |