[go: up one dir, main page]

ATE290323T1 - Fraktionierung von proteinhaltigen mischungen - Google Patents

Fraktionierung von proteinhaltigen mischungen

Info

Publication number
ATE290323T1
ATE290323T1 AT02745177T AT02745177T ATE290323T1 AT E290323 T1 ATE290323 T1 AT E290323T1 AT 02745177 T AT02745177 T AT 02745177T AT 02745177 T AT02745177 T AT 02745177T AT E290323 T1 ATE290323 T1 AT E290323T1
Authority
AT
Austria
Prior art keywords
adsorbent
protein
fractionation
density
mixture
Prior art date
Application number
AT02745177T
Other languages
English (en)
Inventor
Allan Otto Fog Lihme
Marie Bendix Hansen
Inga Vaarst Andersen
Morten Aae Olander
Original Assignee
Upfront Chromatography As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upfront Chromatography As filed Critical Upfront Chromatography As
Application granted granted Critical
Publication of ATE290323T1 publication Critical patent/ATE290323T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1807—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using counter-currents, e.g. fluidised beds
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23J—PROTEIN COMPOSITIONS FOR FOODSTUFFS; WORKING-UP PROTEINS FOR FOODSTUFFS; PHOSPHATIDE COMPOSITIONS FOR FOODSTUFFS
    • A23J1/00—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites
    • A23J1/20—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey
    • A23J1/205—Obtaining protein compositions for foodstuffs; Bulk opening of eggs and separation of yolks from whites from milk, e.g. casein; from whey from whey, e.g. lactalbumine
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/265—Adsorption chromatography
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/42—Selective adsorption, e.g. chromatography characterised by the development mode, e.g. by displacement or by elution
    • B01D15/424—Elution mode
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28011—Other properties, e.g. density, crush strength
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28052—Several layers of identical or different sorbents stacked in a housing, e.g. in a column
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3268—Macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3291—Characterised by the shape of the carrier, the coating or the obtained coated product
    • B01J20/3293—Coatings on a core, the core being particle or fiber shaped, e.g. encapsulated particles, coated fibers
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1864—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns
    • B01D15/1871—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns using two or more columns placed in series

Landscapes

  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02745177T 2001-06-01 2002-05-31 Fraktionierung von proteinhaltigen mischungen ATE290323T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA200100869 2001-06-01
PCT/DK2002/000375 WO2002096215A1 (en) 2001-06-01 2002-05-31 Fractionation of protein containing mixtures

Publications (1)

Publication Number Publication Date
ATE290323T1 true ATE290323T1 (de) 2005-03-15

Family

ID=8160544

Family Applications (3)

Application Number Title Priority Date Filing Date
AT05076246T ATE455468T1 (de) 2001-06-01 2002-05-31 Fraktionierung von proteinhaltigen mischungen
AT05075201T ATE515950T1 (de) 2001-06-01 2002-05-31 Fraktionierung von proteinhaltigen mischungen
AT02745177T ATE290323T1 (de) 2001-06-01 2002-05-31 Fraktionierung von proteinhaltigen mischungen

Family Applications Before (2)

Application Number Title Priority Date Filing Date
AT05076246T ATE455468T1 (de) 2001-06-01 2002-05-31 Fraktionierung von proteinhaltigen mischungen
AT05075201T ATE515950T1 (de) 2001-06-01 2002-05-31 Fraktionierung von proteinhaltigen mischungen

Country Status (8)

Country Link
US (2) US7812138B2 (de)
EP (4) EP1584242B1 (de)
AT (3) ATE455468T1 (de)
AU (1) AU2002316806B2 (de)
DE (2) DE60203176T2 (de)
DK (4) DK2272378T3 (de)
NZ (1) NZ530152A (de)
WO (1) WO2002096215A1 (de)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1584242B1 (de) * 2001-06-01 2010-01-20 Upfront Chromatography A/S Fraktionierung von proteinhaltigen Mischungen
DK1480524T3 (da) 2002-03-07 2013-07-15 Upfront Chromatography As Fremgangsmåde til isolering af lactoferrin
US20070092960A1 (en) * 2003-03-21 2007-04-26 Upfront Chromatography A/S Method for high throughput volumes in the fractionation of bio-molecules by chromatographic systems
AU2012202835B2 (en) * 2004-06-07 2015-02-19 Evolve Biologics Inc. Isolation of plasma or serum proteins
AU2015200328B2 (en) * 2004-06-07 2016-10-06 Evolve Biologics Inc. Isolation of plasma or serum proteins
WO2005121165A1 (en) * 2004-06-07 2005-12-22 Avt Plasma Limited Process for protein isolation
ES2454566T3 (es) * 2004-06-07 2014-04-10 Therapure Biopharma Inc. Aislamiento de proteínas de plasma o suero
SE0502485L (sv) * 2005-11-09 2007-05-10 Peter Viberg Partiklar
US8815551B2 (en) * 2007-01-15 2014-08-26 Upfront Chromatography A/S Production of biofuel and protein from a raw material
EP2115000A1 (de) * 2007-01-29 2009-11-11 Upfront Chromatography A/S Isolierung und aufreinigung von minimal denaturierten kartoffelproteinen und peptiden
DE102007012439A1 (de) * 2007-03-15 2008-09-18 Emsland-Stärke GmbH Verfahren zur Gewinnung pflanzlicher Proteine und/oder Peptide, danach hergestellte Proteine und/oder Peptide und Verwendung derselben
JP5888481B2 (ja) * 2007-03-28 2016-03-22 ディーピーエックス ホールディングス ビー．ブイ． 膨張床カラムおよび使い捨て可能なクロマトグラフィー
KR101593247B1 (ko) 2007-12-03 2016-02-11 디피엑스 홀딩스 비.브이. 비드 제조 시스템 및 방법
US20110160636A1 (en) * 2008-09-10 2011-06-30 Rekha Bansal Device and method for inhibiting complement activation
EP2355664B8 (de) * 2008-09-30 2014-09-10 Upfront Chromatography A/S Verfahren zur Bereitstellung eines beta-Lactoglobulinprodukts und eines alpha-angereicherten Molkenproteinisolats
EP2198946B8 (de) * 2008-12-22 2019-08-07 Glatt Systemtechnik GmbH Absorbierende verbundwerkstoffkügelchen, verfahren zu ihrer herstellung und gastrennungsverfahren
GB201202762D0 (en) 2012-02-17 2012-04-04 Autology Health Ltd High efficiency cell capture
US9351978B2 (en) 2012-02-29 2016-05-31 Mead Johnson Nutrition Company Neurogenesis screening method and uses thereof
BR112015008661A2 (pt) 2012-10-23 2017-07-04 Upfront Chromatography As processos de separação para proteína de soja
CN105188872B (zh) * 2013-03-15 2019-01-15 葛兰素史克知识产权第二有限公司 用于纯化抗体的方法
US9661868B2 (en) * 2013-07-16 2017-05-30 Mead Johnson Nutrition Company Expanded bed adsorption methods for isolation of basic milk proteins including lactoferrin
US9226914B2 (en) 2013-07-16 2016-01-05 Mead Johnson Nutrition Company Methods for promoting neuronal development and/or health
US9241923B2 (en) 2013-07-16 2016-01-26 Mead Johnson Nutrition Company Methods for promoting neuronal development and/or health
US9609888B2 (en) 2013-07-31 2017-04-04 Mead Johnson Nutrition Company Nutritional compositions containing synergistic combination and uses thereof
US10709770B2 (en) 2013-07-31 2020-07-14 Mead Johnson Nutrition Company Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
WO2015050744A2 (en) 2013-10-03 2015-04-09 Mjn U.S. Holdings Llc Neurogenesis screening method and uses thereof
CZ2013885A3 (cs) * 2013-11-15 2015-08-19 Univerzita PalackĂ©ho Způsob separace syrovátkových proteinů z mléčného média a zařízení k provádění tohoto způsobu
US20150157048A1 (en) 2013-12-11 2015-06-11 Mead Johnson Nutrition Company Nutritional compositions containing stearidonic acid and uses thereof
US10028519B2 (en) 2014-03-05 2018-07-24 Mead Johnson Nutrition Company Nutritional compositions containing ceramide and uses thereof
US20150290261A1 (en) 2014-04-10 2015-10-15 Mead Johnson Nutrition Company Methods of use for probiotics and prebiotics
US20150305359A1 (en) 2014-04-24 2015-10-29 Mead Johnson Nutrition Company Nutritional compositions directed to subjects having cow's milk protein allergies
US20150305385A1 (en) 2014-04-25 2015-10-29 Mead Johnson Nutrition Company Pediatric nutritional composition with human milk oligosaccahrides, prebiotics and probiotics
JP6700197B2 (ja) 2014-04-30 2020-05-27 ノヴォ ノルディスク アー／エス カプリル酸を用いてタンパク質を精製する方法
US20160015068A1 (en) 2014-07-16 2016-01-21 Mead Johnson Nutrition Company Nutritional formulas containing oil blends and uses thereof
US20160029682A1 (en) 2014-08-01 2016-02-04 Mead Johnson Nutrition Company Hydrolyzed lactose-containing nutritional compositions and uses thereof
US20160095339A1 (en) 2014-10-01 2016-04-07 Mead Johnson Nutrition Company Nutritional composition for gastrointestinal environment to provide improved microbiome and metabolic profile
CN106793793A (zh) * 2014-10-06 2017-05-31 预层析股份有限公司 来自含有聚集的酪蛋白的混合物的可溶性蛋白的分离
CA2962136A1 (en) 2014-11-07 2016-05-12 Mjn U.S. Holdings Llc Nutritional compositions containing a prebiotic and lactoferrin and uses thereof
DK3097787T3 (en) 2015-05-24 2019-03-11 Dmk Deutsches Milchkontor Gmbh PROCEDURE FOR OBTAINING LACTOPEROXIDASE FROM MILK
DK3097788T3 (en) 2015-05-26 2019-01-28 Dmk Deutsches Milchkontor Gmbh PROCEDURE FOR EXPLORING LACTOFERRIN FROM MILK
US10525016B2 (en) 2015-06-03 2020-01-07 Mead Johnson Nutrition Company Nutritional compositions containing an elevated level of inositol and uses thereof
US10582714B2 (en) 2015-07-10 2020-03-10 Mead Johnson Nutrition Company Nutritional compositions and methods for promoting cognitive development
US20170006897A1 (en) 2015-07-10 2017-01-12 Mead Johnson Nutrition Company Nutritional compositions and methods for promoting cognitive development
US10617701B2 (en) 2015-07-10 2020-04-14 Mead Johnson Nutrition Company Nutritional compositions containing phosphatidylethanolamine, sphingomyelin and docosahexaenoic acid
US20170020950A1 (en) 2015-07-23 2017-01-26 Mead Johnson Nutrition Company Methods for modulating kinases
US9730969B2 (en) 2015-11-06 2017-08-15 Mead Johnson Nutrition Company Nutritional compositions for promoting gut barrier function and ameliorating visceral pain
US10034937B2 (en) 2015-12-04 2018-07-31 Mead Johnson Nutrition Company Synergistic nutritional compositions and uses thereof
EP3225114B1 (de) 2016-03-30 2019-09-11 DMK Deutsches Milchkontor GmbH Verfahren zur herstellung demineralisierte molkepulver
US20180064739A1 (en) 2016-09-06 2018-03-08 Mead Johnson Nutrition Company Nutritional composition with human milk oligosaccharides and uses thereof
KR102489451B1 (ko) 2016-09-07 2023-01-16 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 항체를 정제하는 방법
US20180103675A1 (en) 2016-10-14 2018-04-19 Mead Johnson Nutrition Company Personalized pediatric nutrition products comprising human milk oligosaccharides
US20180133287A1 (en) 2016-11-14 2018-05-17 Mead Johnson Nutrition Company Nutritional compositions providing dietary management of colic
US20180153951A1 (en) 2016-12-05 2018-06-07 Mead Johnson Nutrition Company Methods for Inducing Adipocyte Browning, Improving Metabolic Flexibility, and Reducing Detrimental White Adipocyte Tissue Deposition and Dysfunction
US10980269B2 (en) 2016-12-12 2021-04-20 Mead Johnson Nutrition Company Protein hydrolysates and methods of making same
US20180161292A1 (en) 2016-12-12 2018-06-14 Mead Johnson Nutrition Company Nutritional compositions containing butyrate and uses thereof
US20180160714A1 (en) 2016-12-12 2018-06-14 Mead Johnson Nutrition Company Nutritional compositions containing butyrate and uses thereof
US20180168215A1 (en) 2016-12-21 2018-06-21 Mead Johnson Nutrition Company Nutritional compositions containing inositol and uses thereof
US20180333426A1 (en) 2017-05-17 2018-11-22 Mead Johnson Nutrition Company Nutritional composition with human milk oligosaccharides and uses thereof
US20180332881A1 (en) 2017-05-17 2018-11-22 Mead Johnson Nutrition Company Preterm infant formula containing butyrate and uses thereof
DK201700721A1 (en) * 2017-12-17 2019-06-27 Upfront Chromatography A/S ADSORBENT COMPRISING METAL DIOXIDE
US20190208807A1 (en) 2018-01-05 2019-07-11 Mead Johnson Nutrition Company Nutritional compositions containing milk-derived peptides and uses thereof
CN108408910A (zh) * 2018-03-23 2018-08-17 江苏和合水环境有限公司 组合式浮床净水装置
GB2573538B (en) 2018-05-09 2023-01-04 Mjn Us Holdings Llc Pediatric nutritional compositions and methods for infants delivered by C-section

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1586364A (en) 1976-06-17 1981-03-18 Atomic Energy Authority Uk Porous inorganic materials
JPS5931040B2 (ja) * 1980-09-12 1984-07-30 株式会社日立製作所 放射性廃棄物の造粒装置
US4452773A (en) * 1982-04-05 1984-06-05 Canadian Patents And Development Limited Magnetic iron-dextran microspheres
EP0203163A4 (de) 1984-11-28 1987-09-10 University Patents Inc Affinitätsschromotographie unter verwendung trockener kalziumalginat-magnetit-scheidemittel in einem magnetisch stabilisierten wirbelbett.
FR2575666B1 (fr) * 1985-01-04 1989-08-18 Centre Nat Rech Scient Procede et dispositif pour la separation chromatographique de macromolecules biologiques
IE61701B1 (en) * 1986-07-17 1994-11-30 Morinaga Milk Industry Co Ltd Process for producing bovine lactoferrin in high purity
DK165090D0 (da) 1990-07-09 1990-07-09 Kem En Tec As Konglomererede partikler
DK52791D0 (da) 1991-03-22 1991-03-22 Kem En Tec As Adsorptionsmatricer
SE9101149D0 (sv) 1991-04-17 1991-04-17 Pharmacia Lkb Biotech Beads for down stream processing
DK0620709T3 (da) * 1992-01-15 1995-12-04 Campina Melkunie Bv Fremgangsmåde til isolering af lactoferrin og lactoperoxidase fra mælk og mælkeprodukter
JPH05202098A (ja) * 1992-01-29 1993-08-10 Snow Brand Milk Prod Co Ltd 乳質原料から生理活性物質の製造法
SE9503926D0 (sv) * 1995-11-07 1995-11-07 Pharmacia Biotech Ab Adsorptionsförfarande och separationsmedium
EP0921855B1 (de) 1996-08-30 2003-11-19 Upfront Chromatography A/S Isolierung von immunglobulinen
SE9700383D0 (sv) 1997-02-04 1997-02-04 Pharmacia Biotech Ab An adsorption/separation method and a medium for adsorption/separation
KR20010030665A (ko) * 1997-09-22 2001-04-16 세프라겐 코포레이션 유장 단백질의 순차적 분리법 및 그의 제제
WO1999065586A2 (en) 1998-06-18 1999-12-23 Upfront Chromatography A/S Expanded bed adsorption system
US5986063A (en) * 1998-07-31 1999-11-16 Wisconsin Alumni Research Foundation Isolating β-lactoglobulin and α-lactalbumin by eluting from a cation exchanger without sodium chloride
AU3418900A (en) 1999-03-26 2000-10-16 Upfront Chromatography A/S Fluidised bed purification of bio-macromolecules such as plasmid dna, chromosomal dna, rna, viral dna, bacteria and viruses
US6783962B1 (en) * 1999-03-26 2004-08-31 Upfront Chromatography Particulate material for purification of bio-macromolecules
WO2001085329A2 (en) 2000-05-12 2001-11-15 Upfront Chromatography A/S A bed adsorption system
JP2004516896A (ja) * 2000-12-29 2004-06-10 アップフロント・クロマトグラフィー・アー／エス 細胞外体液からの特異的生体高分子物質の体外捕獲
EP1584242B1 (de) * 2001-06-01 2010-01-20 Upfront Chromatography A/S Fraktionierung von proteinhaltigen Mischungen
DK1480524T3 (da) * 2002-03-07 2013-07-15 Upfront Chromatography As Fremgangsmåde til isolering af lactoferrin

Also Published As

Publication number Publication date
DE60203176D1 (de) 2005-04-14
EP1552752B1 (de) 2011-07-13
ATE515950T1 (de) 2011-07-15
DK1552752T3 (da) 2011-10-03
EP1584242B1 (de) 2010-01-20
EP1401289A1 (de) 2004-03-31
EP1552752A2 (de) 2005-07-13
DE60203176T2 (de) 2006-04-27
AU2002316806B2 (en) 2007-10-25
DK1401289T3 (da) 2005-07-18
EP2272378B1 (de) 2014-08-06
US7956166B2 (en) 2011-06-07
DE60235206D1 (de) 2010-03-11
US20080182979A1 (en) 2008-07-31
US20050065329A1 (en) 2005-03-24
DK1584242T3 (da) 2010-05-25
EP2272378A1 (de) 2011-01-12
EP1584242A1 (de) 2005-10-12
WO2002096215A1 (en) 2002-12-05
EP1401289B1 (de) 2005-03-09
US7812138B2 (en) 2010-10-12
DK2272378T3 (da) 2014-10-06
ATE455468T1 (de) 2010-02-15
EP1552752A3 (de) 2005-10-12
NZ530152A (en) 2005-07-29

Similar Documents

Publication Publication Date Title
ATE455468T1 (de) Fraktionierung von proteinhaltigen mischungen
ATE161866T1 (de) Selektive, die porengrösse betreffende chemische modifikation poröser materialien
KR970020161A (ko) 다층 흡착 베드를 사용하는 흡착 방법 및 장치
TW351678B (en) Method for fractionating a solution to fractionate a solution
DE3886370D1 (de) Integriertes Verfahren für die Entfernung von Schwefelverbindungen aus Fluidströmen.
DE69111917D1 (de) Druckwechsel-Adsorptionsverfahren zur Trennung von Gasgemischen.
DE69106100D1 (de) Verfahren zur Trennung durch Adsorption und Adsorber.
DE69127657D1 (de) Proteinreinigungsmethode
DE60334909D1 (de) Poröse perlen und herstellungsverfahren dafür
TW327611B (en) Process for purifying fluids by temperature swing adsorption process
DE69531051D1 (de) Zeolitisches Sorptionsmittel zur selektiven Adsorption von Stickstoff in Lufttrennungsverfahren
KR890006277A (ko) 자기적으로 안정화된 유동화베드에서의 동일이동성 집속
DE69125764D1 (de) Verfahren zur Herstellung des Von Willebrand-Faktors von höchster Reinheit
EP0810027A4 (de) Adsorbens für tumornecrosisfactor alpha, methode zur entfernung durch adsorption und adsorptionsvorrichtung unter verwendung des adsorben
ATE368506T1 (de) Gastrennkörper und verfahren zur herstellung desselben
DE59204385D1 (de) Verfahren zur Sauerstoffanreicherung.
ATE332187T1 (de) Verfahren zum herstellen eines adsorbens zum absenken der konzentration von fibrinogen und/oder fibrin, adsorbens und verwendung des adsorbens zur herstellung eines adsorbers
ATE242782T1 (de) Verfahren zur herstellung von peptiden aus biologischen flüssigkeiten und nach diesem verfahren herstellbare peptide
DK0691393T3 (da) Fremgangsmåde til tørring af en gas-eller væskeformig blanding ved hjælp af adsorber bestående af aluminiumoxid og en molek
DK0415079T5 (da) Formede organosiloxanamin-copolykondensater, fremgangsmåde til deres fremstilling og deres anvendelse
ATE142345T1 (de) Bioysnthetische gehirnruckenmarkflussigkeitskontrolle und verfahren zu deren herstellung
AU2433484A (en) Method for producing cellular material of the mixed porous/ capillary type of which the permeability may be modified as desired.
SE8302589L (sv) Gasseparationsforfarande
DE69514671D1 (de) Gips und asche enthaltende granulate zur anreicherung von böden und verfahren zur herstellung dieser granulate
ES2127695A1 (es) Procedimiento para la reduccion del contenido de factor plaquetar 4 en proteinas plasmaticas que poseen afinidad a heparina.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties