ATE282594T1 - Verfahren zur herstellung von (+)-trans-4-p- fluorophenyl-3-hydroxymethyl-1-methylpiperidin - Google Patents
Verfahren zur herstellung von (+)-trans-4-p- fluorophenyl-3-hydroxymethyl-1-methylpiperidinInfo
- Publication number
- ATE282594T1 ATE282594T1 AT01901146T AT01901146T ATE282594T1 AT E282594 T1 ATE282594 T1 AT E282594T1 AT 01901146 T AT01901146 T AT 01901146T AT 01901146 T AT01901146 T AT 01901146T AT E282594 T1 ATE282594 T1 AT E282594T1
- Authority
- AT
- Austria
- Prior art keywords
- fluorophenyl
- trans
- methylpiperidine
- hydroxymethyl
- producing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/34—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
- C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hydrogenated Pyridines (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2001/000049 WO2002053537A1 (en) | 2001-01-04 | 2001-01-04 | Process for preparing (±) trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE282594T1 true ATE282594T1 (de) | 2004-12-15 |
Family
ID=8164242
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01901146T ATE282594T1 (de) | 2001-01-04 | 2001-01-04 | Verfahren zur herstellung von (+)-trans-4-p- fluorophenyl-3-hydroxymethyl-1-methylpiperidin |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6881845B2 (de) |
| EP (1) | EP1347960B1 (de) |
| JP (1) | JP2004520333A (de) |
| KR (1) | KR20030067742A (de) |
| AT (1) | ATE282594T1 (de) |
| BR (1) | BR0116721A (de) |
| CA (1) | CA2433605A1 (de) |
| DE (1) | DE60107292T2 (de) |
| DK (1) | DK1347960T3 (de) |
| ES (1) | ES2232588T3 (de) |
| IL (1) | IL156768A0 (de) |
| MX (1) | MXPA03006057A (de) |
| NO (1) | NO20033049L (de) |
| NZ (1) | NZ526874A (de) |
| PT (1) | PT1347960E (de) |
| TW (1) | TW593279B (de) |
| WO (1) | WO2002053537A1 (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2001290873B2 (en) * | 2000-09-11 | 2006-07-27 | Sepracor Inc. | Ligands for monoamine receptors and transporters, and methods of use thereof (neurotransmission) |
| DE10240026A1 (de) * | 2002-08-27 | 2004-03-11 | Merck Patent Gmbh | Verfahren zur Herstellung von Monoalkylaminoketonen |
| WO2004043921A1 (en) * | 2002-11-11 | 2004-05-27 | Natco Pharma Limited | Novel process for the preparation of 4-aryl-3-hydroxymethyl-1-methylpiperidines. |
| WO2005063707A1 (en) * | 2003-12-26 | 2005-07-14 | Natco Pharma Limited | Enantiospecific process for the preparation of paroxetine intermediate |
| WO2007089193A1 (en) * | 2006-02-02 | 2007-08-09 | Astrazeneca Ab | A process for preparing 2-hydroxy-3- [5- (morpholin-4-ylmethyl)pyridin-2-yl] lh-indole-5-carbonitrile as a free base or salts thereof |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| WO2022269643A1 (en) * | 2021-06-25 | 2022-12-29 | Vihita Chem Private Limited | An improved process for the preparation of intermediate for paroxetine |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1422263A (en) * | 1973-01-30 | 1976-01-21 | Ferrosan As | 4-phenyl-piperidine compounds |
| DE3680184D1 (de) * | 1985-08-10 | 1991-08-14 | Beecham Group Plc | Verfahren zur herstellung von arylpiperidincarbinol. |
| DK715988D0 (da) * | 1988-12-22 | 1988-12-22 | Ferrosan As | Etherifikation og dealkylering af piperidin-derivater samt intermediater |
| WO1996036636A1 (en) * | 1995-05-17 | 1996-11-21 | Novo Nordisk A/S | Process for preparing 4-aryl-piperidine derivatives |
| EP1384720A1 (de) | 1996-06-13 | 2004-01-28 | SUMIKA FINE CHEMICALS Co., Ltd. | Verfahren zur Trocknung von Paroxetinhydrochlorid |
| JP2002514222A (ja) * | 1997-05-29 | 2002-05-14 | スミスクライン・ビーチャム・コーポレイション | 新規方法 |
| WO2000026187A1 (en) * | 1998-11-02 | 2000-05-11 | Synthon B.V. | Process for producing 4-arylpiperidine-3-carbinols and related compounds |
-
2001
- 2001-01-04 DE DE60107292T patent/DE60107292T2/de not_active Expired - Fee Related
- 2001-01-04 NZ NZ526874A patent/NZ526874A/en unknown
- 2001-01-04 IL IL15676801A patent/IL156768A0/xx unknown
- 2001-01-04 BR BR0116721-9A patent/BR0116721A/pt not_active IP Right Cessation
- 2001-01-04 AT AT01901146T patent/ATE282594T1/de not_active IP Right Cessation
- 2001-01-04 PT PT01901146T patent/PT1347960E/pt unknown
- 2001-01-04 EP EP01901146A patent/EP1347960B1/de not_active Expired - Lifetime
- 2001-01-04 JP JP2002554656A patent/JP2004520333A/ja not_active Abandoned
- 2001-01-04 CA CA002433605A patent/CA2433605A1/en not_active Abandoned
- 2001-01-04 DK DK01901146T patent/DK1347960T3/da active
- 2001-01-04 WO PCT/EP2001/000049 patent/WO2002053537A1/en not_active Application Discontinuation
- 2001-01-04 US US10/250,519 patent/US6881845B2/en not_active Expired - Fee Related
- 2001-01-04 MX MXPA03006057A patent/MXPA03006057A/es not_active Application Discontinuation
- 2001-01-04 KR KR10-2003-7009058A patent/KR20030067742A/ko not_active Application Discontinuation
- 2001-01-04 ES ES01901146T patent/ES2232588T3/es not_active Expired - Lifetime
- 2001-02-27 TW TW090104450A patent/TW593279B/zh not_active IP Right Cessation
-
2003
- 2003-07-03 NO NO20033049A patent/NO20033049L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA03006057A (es) | 2004-01-26 |
| WO2002053537A1 (en) | 2002-07-11 |
| KR20030067742A (ko) | 2003-08-14 |
| DK1347960T3 (da) | 2005-03-21 |
| EP1347960B1 (de) | 2004-11-17 |
| DE60107292D1 (de) | 2004-12-23 |
| US6881845B2 (en) | 2005-04-19 |
| US20040215020A1 (en) | 2004-10-28 |
| JP2004520333A (ja) | 2004-07-08 |
| PT1347960E (pt) | 2005-03-31 |
| ES2232588T3 (es) | 2005-06-01 |
| WO2002053537A8 (en) | 2002-08-08 |
| CA2433605A1 (en) | 2002-07-11 |
| IL156768A0 (en) | 2004-02-08 |
| BR0116721A (pt) | 2003-12-23 |
| NO20033049D0 (no) | 2003-07-03 |
| EP1347960A1 (de) | 2003-10-01 |
| DE60107292T2 (de) | 2005-12-01 |
| NZ526874A (en) | 2005-07-29 |
| NO20033049L (no) | 2003-08-18 |
| TW593279B (en) | 2004-06-21 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE59108707D1 (de) | Verfahren zur Herstellung von Oxetanonen | |
| ATE410412T1 (de) | Oxopyrrolidin verbindungen, verfahren zur herstellung dieser verbindungen und deren verwendung zur herstellung von levetiracetam und analogen | |
| ATE407127T1 (de) | Verfahren zur herstellung von beraprost und dessen salzen | |
| DE69915713D1 (de) | Verfahren zur herstellung von citalopram | |
| DE60107292D1 (de) | Verfahren zur herstellung von (+)-trans-4-p-fluorophenyl-3-hydroxymethyl-1-methylpiperidin | |
| ATE457972T1 (de) | Verfahren zur herstellung von 7-amino-syn-3,5- dihydroxyheptansäurederivaten und zwischenverbindungen diesesverfahrens und deren herestellung | |
| ATE281434T1 (de) | Verfahren zur herstellung von benzoperhydroisoindolen | |
| DE60224884D1 (de) | Verfahren zur herstellung von 3, 3', 6, 6'-tetraalkylen-2, 2'-biphenolen und 3, 3', 6, 6'-tetraalkylen-5, 5'-dihalo-2, 2' biphenolen | |
| DE50309260D1 (de) | Verfahren zur herstellung von bicalutamid | |
| ATE496038T1 (de) | Verfahren zur herstellung von quetiapin | |
| ATE299851T1 (de) | Verfahren zur herstellung von zwischenprodukten | |
| ATE273278T1 (de) | Verfahren zur herstellung von 5-aminomethyl-2- chlorpyridinen | |
| DE59907056D1 (de) | Verfahren zur herstellung von cyclen | |
| ATE330612T1 (de) | Verfahren zur herstellung von benazeprilhydrochloride | |
| ATE265421T1 (de) | Verfahren zur herstellung von midodrin | |
| ATE404540T1 (de) | Verfahren zur herstellung von 1-substituierten 5- chlor-4methylpyrazolen | |
| ATE425143T1 (de) | Verfahren zur herstellung von indolen | |
| DE60229261D1 (de) | Verfahren zur herstellung von säureanhydrid | |
| DE69514512D1 (de) | Verfahren zur herstellung von benzopyranderivaten | |
| ATE297478T1 (de) | Verfahren zur herstellung von orthocarbonsäuretrialkylestern | |
| ATE309226T1 (de) | Verfahren zur herstellung von fluconazole und kristallmodifikationen davon | |
| DE50312447D1 (de) | Verfahren zur herstellung von 4,6-dichlor-5-fluorpyrimidin | |
| DE60007137D1 (de) | Verfahren zur herstellung von 2-arylvinylalkylethern und 1,4-diaryl-2-fluor-2-butenen | |
| ATE281428T1 (de) | Verfahren zur herstellung von methoxyimino- essigsäureamiden | |
| ATE325111T1 (de) | Verfahren zur herstellung von 15-pentadecanolid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1347960 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |